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Cerebrum
Cerebrum
• Largest part of brain
• Divided into 2 hemispheres
• Controls all conscious thoughts &
intellectual functions
• Processes somatic motor and sensory
information
External features
• Poles
• Surfaces
• Borders
• Sulci & gyri
Poles
• 3 poles
• Frontal
• Occipital
• Temporal
Surfaces
• 3 surfaces
• Superolateral surface
• Medial surface
• Inferior surface
Borders
• 3 borders
• Superomedial
• Inferolaeral
• Inferomedial
• Medial orbital
• Medial occipital
•
Gyrus & sulci
• To increase surface area
• To accommodate more neurons
• Sulcus
• Indentation (groove)
• Gyrus
• Ridge (elevation)
Fissures
• Deep groove
• Longitudinal fissure
• Separates two hemispheres
Grey & white matter
• Outside
• Cortex
• Neurons present
• White
• Axons present
Main Sulci
• On superolateral surface
• Two prominent sulci are present
• Posterior ramus of the lateral sulcus
• Central sulcus
• On medial surface - near occipital pole
• Parietooccipital sulcus
• Upper end of this sulcus reaches
superomedial border
• Small part of it can be seen on superolateral
surface
Lobes
• Frontal lobe
• Anterior to central sulcus and
• Above posterior ramus of lateral sulcus
• Parietal lobe
• Behind central sulcus
• Bounded below by posterior ramus of the
lateral sulcus and by the second
imaginary line and
• Behind by the upper part of the first
imaginary line
Lobes
• Occipital lobe
• Area lying behind the first imaginary
line connecting parieto-occipital sulcus
and pre-occipital notch
• Temporal lobe
• Below posterior ramus of the lateral
sulcus and the second imaginary line
• Separated from the occipital lobe by the
lower part of the first imaginary line
Sulci and gyri of frontal lobe
• Precentral sulcus
• Superior frontal sulcus
• Inferior frontal sulcus
• Precentral gyrus
• Superior frontal gyrus
• Middle frontal gyrus
• Inferior frontal gyrus
Sulci and gyri of parietal lobe
• Postcentral sulcus
• Intraparietal sulcus
• Postcentral gyrus
• Superior parietal lobule
• Inferior parietal lobule
• Supramarginal gyrus
• Angular gyrus
• Arcus temporo-occipitalis
Sulci and gyri of temporal lobe
• Superior temporal
sulcus
• Inferior temporal
sulcus
• Superior temporal gyrus
• Middle temporal gyrus
• Inferior temporal gyrus
• Transverse temporal gyri
Sulci & gyri of occipital lobe
• Lateral occipital sulcus
• Divides the lateral surface into
• Superior occipital gyrus
• Inferior occipital gyrus
• Lunate sulcus
• Transverse occipital sulcus
• Lies posterior to parieto-occipital sulcus
• Gyrus descendens
• Arcus parietooccipitalis
Sulci & gyri on medial surface
• Callosal sulcus
• Cingulate sulcus
• Short sulcus
• Cingulate gyrus
• Paracentral lobule
• Medial frontal gyrus
Sulci & gyri on medial surface
• Suprasplenial sulcus
• Parietooccipital sulcus
• Calcarine sulcus
• Cuneus
• Precuneus
• Isthmus
Structures in inferior surface
• In centre
• Interpeduncular fossa
• Between 2 cerebral
hemispheres
• Inferior surface of
hemisphere can be
divided into
• Orbital & tentorial
surfaces
Interpeduncular fossa
• Lies anterior to midbrain
• Boundaries
• In front by
• Optic chiasma
• Anterolatealrly by
• Right and left optic tracts
• Posterolaterally
• Crus cerebri
• Posteriorly
• Pons
Sulci & gyri on orbital surface
• Olfactory sulcus
• Antero posterior sulcus near medial border
• Olfactory bulb & tract
• Gyrus rectus
• Medial to olfactory sulcus
• Orbital sulcus
• H – shaped
• Anterior, posterior, medial & lateral orbital gyri
Sulci & gyri on tentorial surface
• Collateral sulcus
• Near medial border
• Posteriorly forms lateral boundary for Lingual gyrus
• Anteriorly forms lateral boundary for parahippocampal gyrus
• Rhinal sulcus
• Separates uncus from medial occipito temporal gyrus
• Occipitotemporal sulcus
• Lateral one
• Divides the remaining gyri into
• Medial & lateral occipito temporal gyri
Insula
• Submerged part of cerebral cortex
• Found in depth of lateral sulcus
• Surrounded by circular sulcus
Lentiform nucleus lies deep to it
Functional Areas of Cerebral Cortex
• In 1909, Brodmann’s areas
were described based on
cytoarchitecture
• Later they were found to be
functionally significant
• Cytoarchitecture is based on
• Density of different cortical
neurons and thickness of layers
•
• 6 layers are present in cortex
• Molecular –outermost
• Outer granular – stellate & granule cells
• Outer pyramidal – small & medium
• Inner granular – stellate cells
• Inner pyramidal – medium & large
• Polymorphous – Marinoti cells & multipolar
Functional areas in frontal lobe
• Primary motor
• Premotor
• Frontal eye field
• Supplementary motor
• Prefrontal
• Broca’s area
Functional areas in frontal lobe
• Precentral motor cortex (area 4)
• Infront of central sulcus including anterior
wall of central sulcus
• Anterior part of paracentral lobule
• Has large pyramidal cells of Betz
• Opposite side body is topographically
represented
• In upside down manner (head is lower and leg
is up
• Lower limb and perineum are on medial side
• Controls highly skilled voluntary
movement of opposite half of body
• Voluntary control of micturition &
defecation are in anterior part of
paracentral lobule
Functional areas in frontal lobe
• Premotor cortex (area 6)
• Lies infront of motor cortex
• In posterior parts of superior middle and
inferior frontal gyri
• Inferiorly upto lateral sucus
• Superiorly extends into medial surface
• Anterior to paracentral lobule
• Upper part – writing centre
• Lower part & around ascending ramus
of lateral sulcus
• Motor speech area (44 & 45) (Broca’s area)
Functional areas in frontal lobe
• Frontal eye field (8)
• Ability of the eyes to work together
• To follow an object
• Lies infront of upper part of premotor
area
• In posterior part of middle frontal gyrus
• Controls conjugate movements of eye
• Prefrontal cortex (9, 10 & 11)
• Essential for thought process
• Examples
• Solving mathematical problems
• Having foresight
• Giving judgments
Functional areas in frontal lobe
• Supplementary motor area (24)
• Primary motor area (6) continues on
medial surface
• Function
• Programming sequential motor
movements
• Lesion
• Results loss in coordination in
movements of two limbs
Functional areas in parietal lobe
• Primary somatosensory
• Secondary somatosensory
• Gustatory
• Association
Functional areas in parietal lobe
• Primary somatosensory area (3, 1 & 2)
• Lies in
• Posterior wall (3) and lip of central sulcus (1)
• Post central gyrus (2)
• Extends into paracentral lobule
• Receives sense of bladder & rectum fullness
• Functions
• Tactile localization between the 2 points discrimination & tactile
discrimination between 2 objects
Functional areas in parietal lobe
• Secondary somatosensory
• Lies along
• Upper lip of Posterior ramus of
lateral sulcus
• Functions
• Responds to stroking the skin
by brush or tapping
Functional areas in parietal lobe
• Somesthetic association area (5)
• Lies in
• Anterior part of superior parietal lobule
• Function
• Integrates tactile & visual stimuli
• To determine shape & size of an object
Functional areas in temporal lobe
• Primary auditory (41 & 42))
• Auditory association (22)
• Visual association
• Limbic
Functional areas in temporal lobe
• Primary auditory area (41 & 42)
• Located in
• Transverse temporal gyrus
• In floor of posterior ramus of lateral sulcus &
adjoining superior temporal gyrus
• Function
• Detecting the direction of the sound
Functional areas in temporal lobe
• Auditory association area (22)
• Lies around primary auditory area
• In middle of superior temporal gyrus
Functional areas in occipital lobe
• Primary visual cortex (17)
• Called as striate cortex
• Lies in
• Lips & walls of
• Posterior part of calcarine sulcus
Functional areas in occipital lobe
• Second visual area (18)
• Lies close to primary visual area
• Function
• Understand the written language

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Cerebrum

  • 2. Cerebrum • Largest part of brain • Divided into 2 hemispheres • Controls all conscious thoughts & intellectual functions • Processes somatic motor and sensory information
  • 3. External features • Poles • Surfaces • Borders • Sulci & gyri
  • 4. Poles • 3 poles • Frontal • Occipital • Temporal
  • 5. Surfaces • 3 surfaces • Superolateral surface • Medial surface • Inferior surface
  • 6. Borders • 3 borders • Superomedial • Inferolaeral • Inferomedial • Medial orbital • Medial occipital •
  • 7. Gyrus & sulci • To increase surface area • To accommodate more neurons • Sulcus • Indentation (groove) • Gyrus • Ridge (elevation)
  • 8. Fissures • Deep groove • Longitudinal fissure • Separates two hemispheres
  • 9. Grey & white matter • Outside • Cortex • Neurons present • White • Axons present
  • 10. Main Sulci • On superolateral surface • Two prominent sulci are present • Posterior ramus of the lateral sulcus • Central sulcus • On medial surface - near occipital pole • Parietooccipital sulcus • Upper end of this sulcus reaches superomedial border • Small part of it can be seen on superolateral surface
  • 11. Lobes • Frontal lobe • Anterior to central sulcus and • Above posterior ramus of lateral sulcus • Parietal lobe • Behind central sulcus • Bounded below by posterior ramus of the lateral sulcus and by the second imaginary line and • Behind by the upper part of the first imaginary line
  • 12. Lobes • Occipital lobe • Area lying behind the first imaginary line connecting parieto-occipital sulcus and pre-occipital notch • Temporal lobe • Below posterior ramus of the lateral sulcus and the second imaginary line • Separated from the occipital lobe by the lower part of the first imaginary line
  • 13. Sulci and gyri of frontal lobe • Precentral sulcus • Superior frontal sulcus • Inferior frontal sulcus • Precentral gyrus • Superior frontal gyrus • Middle frontal gyrus • Inferior frontal gyrus
  • 14. Sulci and gyri of parietal lobe • Postcentral sulcus • Intraparietal sulcus • Postcentral gyrus • Superior parietal lobule • Inferior parietal lobule • Supramarginal gyrus • Angular gyrus • Arcus temporo-occipitalis
  • 15. Sulci and gyri of temporal lobe • Superior temporal sulcus • Inferior temporal sulcus • Superior temporal gyrus • Middle temporal gyrus • Inferior temporal gyrus • Transverse temporal gyri
  • 16. Sulci & gyri of occipital lobe • Lateral occipital sulcus • Divides the lateral surface into • Superior occipital gyrus • Inferior occipital gyrus • Lunate sulcus • Transverse occipital sulcus • Lies posterior to parieto-occipital sulcus • Gyrus descendens • Arcus parietooccipitalis
  • 17. Sulci & gyri on medial surface • Callosal sulcus • Cingulate sulcus • Short sulcus • Cingulate gyrus • Paracentral lobule • Medial frontal gyrus
  • 18. Sulci & gyri on medial surface • Suprasplenial sulcus • Parietooccipital sulcus • Calcarine sulcus • Cuneus • Precuneus • Isthmus
  • 19. Structures in inferior surface • In centre • Interpeduncular fossa • Between 2 cerebral hemispheres • Inferior surface of hemisphere can be divided into • Orbital & tentorial surfaces
  • 20. Interpeduncular fossa • Lies anterior to midbrain • Boundaries • In front by • Optic chiasma • Anterolatealrly by • Right and left optic tracts • Posterolaterally • Crus cerebri • Posteriorly • Pons
  • 21. Sulci & gyri on orbital surface • Olfactory sulcus • Antero posterior sulcus near medial border • Olfactory bulb & tract • Gyrus rectus • Medial to olfactory sulcus • Orbital sulcus • H – shaped • Anterior, posterior, medial & lateral orbital gyri
  • 22. Sulci & gyri on tentorial surface • Collateral sulcus • Near medial border • Posteriorly forms lateral boundary for Lingual gyrus • Anteriorly forms lateral boundary for parahippocampal gyrus • Rhinal sulcus • Separates uncus from medial occipito temporal gyrus • Occipitotemporal sulcus • Lateral one • Divides the remaining gyri into • Medial & lateral occipito temporal gyri
  • 23. Insula • Submerged part of cerebral cortex • Found in depth of lateral sulcus • Surrounded by circular sulcus Lentiform nucleus lies deep to it
  • 24. Functional Areas of Cerebral Cortex • In 1909, Brodmann’s areas were described based on cytoarchitecture • Later they were found to be functionally significant • Cytoarchitecture is based on • Density of different cortical neurons and thickness of layers • • 6 layers are present in cortex • Molecular –outermost • Outer granular – stellate & granule cells • Outer pyramidal – small & medium • Inner granular – stellate cells • Inner pyramidal – medium & large • Polymorphous – Marinoti cells & multipolar
  • 25. Functional areas in frontal lobe • Primary motor • Premotor • Frontal eye field • Supplementary motor • Prefrontal • Broca’s area
  • 26. Functional areas in frontal lobe • Precentral motor cortex (area 4) • Infront of central sulcus including anterior wall of central sulcus • Anterior part of paracentral lobule • Has large pyramidal cells of Betz • Opposite side body is topographically represented • In upside down manner (head is lower and leg is up • Lower limb and perineum are on medial side • Controls highly skilled voluntary movement of opposite half of body • Voluntary control of micturition & defecation are in anterior part of paracentral lobule
  • 27. Functional areas in frontal lobe • Premotor cortex (area 6) • Lies infront of motor cortex • In posterior parts of superior middle and inferior frontal gyri • Inferiorly upto lateral sucus • Superiorly extends into medial surface • Anterior to paracentral lobule • Upper part – writing centre • Lower part & around ascending ramus of lateral sulcus • Motor speech area (44 & 45) (Broca’s area)
  • 28. Functional areas in frontal lobe • Frontal eye field (8) • Ability of the eyes to work together • To follow an object • Lies infront of upper part of premotor area • In posterior part of middle frontal gyrus • Controls conjugate movements of eye • Prefrontal cortex (9, 10 & 11) • Essential for thought process • Examples • Solving mathematical problems • Having foresight • Giving judgments
  • 29. Functional areas in frontal lobe • Supplementary motor area (24) • Primary motor area (6) continues on medial surface • Function • Programming sequential motor movements • Lesion • Results loss in coordination in movements of two limbs
  • 30. Functional areas in parietal lobe • Primary somatosensory • Secondary somatosensory • Gustatory • Association
  • 31. Functional areas in parietal lobe • Primary somatosensory area (3, 1 & 2) • Lies in • Posterior wall (3) and lip of central sulcus (1) • Post central gyrus (2) • Extends into paracentral lobule • Receives sense of bladder & rectum fullness • Functions • Tactile localization between the 2 points discrimination & tactile discrimination between 2 objects
  • 32. Functional areas in parietal lobe • Secondary somatosensory • Lies along • Upper lip of Posterior ramus of lateral sulcus • Functions • Responds to stroking the skin by brush or tapping
  • 33. Functional areas in parietal lobe • Somesthetic association area (5) • Lies in • Anterior part of superior parietal lobule • Function • Integrates tactile & visual stimuli • To determine shape & size of an object
  • 34. Functional areas in temporal lobe • Primary auditory (41 & 42)) • Auditory association (22) • Visual association • Limbic
  • 35. Functional areas in temporal lobe • Primary auditory area (41 & 42) • Located in • Transverse temporal gyrus • In floor of posterior ramus of lateral sulcus & adjoining superior temporal gyrus • Function • Detecting the direction of the sound
  • 36. Functional areas in temporal lobe • Auditory association area (22) • Lies around primary auditory area • In middle of superior temporal gyrus
  • 37. Functional areas in occipital lobe • Primary visual cortex (17) • Called as striate cortex • Lies in • Lips & walls of • Posterior part of calcarine sulcus
  • 38. Functional areas in occipital lobe • Second visual area (18) • Lies close to primary visual area • Function • Understand the written language