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The collective centre of the Belgian technology industry



                                     le centre collectif de l’industrie technologique belge
Our centre




       Federation                                Collective centre
       for the technology industry               of the technology industry
                                                 • Nonprofit organisation
                                                 • Industry owned


                                     Mission
                                                 competitiveness of
                                     “Increase the
                                     companies of the Agoria sectors through
                                     technological innovations”


                                         © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011   2
CENG
Our technological sectors




      Aerospace Automotive Construction products
  Contracting & Maintenance Electrical engineering
        Industrial automation Mechatronical engineering

Information and communication technologies (ICT)
  Metals & materials Metal processing Mounting & cranes
        Plastics & composites Security & defence
Local presence, near the companies

    Ghent                                  Leuven
    Materials Engineering                Mechatronics
                                  Technology Coaching




    Brussels                               Hasselt
    Software Engineering & ICT    Materials Engineering
    Technology Coaching          Production Technology




                                               Liège
    Charleroi                    Additive Manufacturing
    Additive Manufacturing        Materials Engineering
    Bio-Manufacturing Platform            Nanomaterials
Additive Manufacturing Process

                                                                                               3D CAD File


       •   Basic data :
           Scan / 3D CAD files – STL


       •   Pre-treatment :                                                        3D STL File
           STL corrections, orientation, supports, 2D slicing


       •   Manufacturing :
           Full automatic

                                                                                                                Sliced File
       •   Post-treatment :
           Cleaning, sand blasting, coating, finishing

                                                                                                Σ 2D layers



                                            © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011        5
CENG
Rapid Prototyping vs Additive Manufacturing

        Rapid Prototyping                                Additive Manufacturing
        •   Stereolithography                            •     Electron Beam Melting
        •   Bi-material 3D Printing                      •     Selective Laser Melting
        •   3D Printing of wax                           •     Laser Cladding
        •   Selective Laser Sintering                    •     Hybrids of Stereolithography
        •   3D Printing of polymers / plaster


                                            Functional
                                              parts



                                        Visual               Final
                                        parts                parts




                                                 © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011   6
CENG
Sirris ADD capacities & competencies

       SIRRIS – World leader: Most complete machine park

           • 15 engineers and technicians
           • Two locations: Liège (10 p.) and Charleroi (5 p.)

       Rapid Prototyping / Tooling / Manufacturing

           •   Stereolithography (normal & hi-res)
           •   Paste polymerisation for ceramics and metals (Optoform)
           •   3D Printing of plaster and metal powder
           •   Laser sintering of polymeric powder (PA,…): P360 – P390
           •   Objet Connex 500: bi-material
           •   Laser sintering of metal powder (parts and mould inserts)
           •   Electron Beam Melting (Arcam A2)
           •   3D Printing of wax (Thermojet)
           •   Vacuum Casting of Alu, Bronze, Zamak
           •   Laser Cladding (EasyClad)
           •   Selective Laser melting (MTT)




                                                      © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011   7
CENG
Benefits of Additive Manufacturing @ Medical field

       •            Evolution of medical imagery technology
                    => Easy access to 3D world !


                    Need for custom implants !
                    Every human is different (anatomy)



                    Need of flexibility, complex structures and fast
                    response for surgery! Very small or even
                    standard (large) manufacturing series possible

                                          © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011   8
CENG
The utility of Additive Manufacturing technologies
       in the medical field

       Next generation pre-operative manufactured implants:

       • Custom implant manufacture :
            • CT-Scan
            • CAD File of the patient is produced
            • Engineer + Surgeon 3D implant approved
            • FEM analysis (when needed)
            • Custom manufacturing (low cost)
            • Surgery
            • Follow up
                                                                                                       [Sirris ADD]




                                        [Sirris ADD]
                                                                                                        [Sirris ADD]




                                                       © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011   9
CENG
ADD capacities & competencies

       Medical Additive Manufacturing Software:

        •   Materialise: Mimics
        •   Materialise: 3-matic
        •   Marcam: Autofab
        •   Able Software Corp: 3D Doctor
        •   Medicim: Maxilim
        •   ProEngineer
        •   New: Lenexa: Analyze
        •   New: Brisbane: Anatomics
        •   (…)




                                                                         [Mimics & 3-matic - Materialise]



                                            © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011   10
CENG
Indirect Manufacturing: Optoform process




                                le centre collectif de l’industrie technologique belge
CENG
Optoform
       Generalities:

       • Commercially not available any more
       • Flexible technology (hybrid SLA):
            •Development of very different materials
       • Possible materials:
            •Soft, hard, metallic and ceramic
       • ISO 13485 certified @ Sirris


       Fabrication steps:

       •   Preparation and fabrication of the bulk material
       •   CAO / CAD File processing
       •   Automated process manufacturing
       •   Cleaning and recycling of the non-used material
       •   Debinding & Sintering process
                                                                                       [Sirris ADD]




                                                          © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   12
CENG
Optoform
       Features:

       • Layer thickness: 20 - 200µm
       • Argon laser 400-800mWatt at 351nm and 365nm
       • Max. Size: 250-350-500mm
       • Several building plates with variable sizes well suited to small parts and
       expensive materials
       • Supports needed


       Material Requirements:

       • Composition :
            Resin+ Fillers (20% to 70% Vol.) + Photo-initiator + Wetting agent +
            rheological/ thixotropic Agent
       • Consistency : Firmness of a toothpaste (Bingham’s model)
       • Good Lifetime : the filler should not deposit sediment
       • No UV absorption by the filler ↔ Layer thickness
       • Support removal & cleaning: not always easy (isopropanol, water,…)



                                                         © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   13
CENG
Optoform




            [Sirris ADD]                     [Sirris ADD]




                           © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   14
CENG
Optoform
       Materials:

       • Alumina
       • Alumina with 8% of nano Zirconia
       • Hydroxyapatite
       • α & β Tri-calciumphosphate
       • Zirconia
       • SiC                                          [Sirris ADD]
       • Stainless steel
       • Titanium                                                                              [Sirris ADD]


       • Ceramics & metals need a post-process of debinding & sintering




                                       [Sirris ADD]


              [Sirris ADD]                                                      [Sirris ADD]




                                                        © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   15
CENG
Optoform & medical field: CASE STUDIES

       Ongoing statuts:

       • Porous scaffolds in Hydroxyapatite Ca5(PO4)3(OH)
       • Diameter ~= 10mm
       • Macro-porosity ~= 0,5mm
       • Tests various scaffold structures for bone integration
       • In vivo testing (rabbits & rats)
       • Field: Spinal implants & Maxillofacial Surgery
       • Spinal implants (HAP/TCP): 10.000 manufactured so far (November 2011)




              [Sirris ADD]          [Sirris ADD]       [Sirris ADD]                   [Sirris ADD]




                                                         © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   16
CENG
Optoform & medical field: CASE STUDIES




                                                            [Sirris ADD]
                            [Sirris ADD]




                                                          0,5mm


             [Sirris ADD]   [Sirris ADD]                    [Sirris ADD]




                                           © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   17
CENG
Optoform & medical field: CASE STUDIES




                [Sirris ADD]                      [Sirris ADD]




                                   © Sirris | www.sirris.be | info@sirris.be | 06/12/2011   18
CENG
Sirris Additive Manufacturing: Contact



                      Carsten ENGEL

                      R&D Biomedical Engineer


                      Mail: carsten.engel@sirris.be
                      Mobile: +32 498 91 94 50
                      Skype: Carsten-Engel

                      SIRRIS
                      Rue Auguste Piccard, 20
                      B-6041 GOSSELIES BELGIUM
                      http://www.sirris.be




                                       © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011   19
CENG

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Sirris Medical Ceramic Applications

  • 1. The collective centre of the Belgian technology industry le centre collectif de l’industrie technologique belge
  • 2. Our centre Federation Collective centre for the technology industry of the technology industry • Nonprofit organisation • Industry owned Mission competitiveness of “Increase the companies of the Agoria sectors through technological innovations” © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011 2 CENG
  • 3. Our technological sectors Aerospace Automotive Construction products Contracting & Maintenance Electrical engineering Industrial automation Mechatronical engineering Information and communication technologies (ICT) Metals & materials Metal processing Mounting & cranes Plastics & composites Security & defence
  • 4. Local presence, near the companies Ghent Leuven Materials Engineering Mechatronics Technology Coaching Brussels Hasselt Software Engineering & ICT Materials Engineering Technology Coaching Production Technology Liège Charleroi Additive Manufacturing Additive Manufacturing Materials Engineering Bio-Manufacturing Platform Nanomaterials
  • 5. Additive Manufacturing Process 3D CAD File • Basic data : Scan / 3D CAD files – STL • Pre-treatment : 3D STL File STL corrections, orientation, supports, 2D slicing • Manufacturing : Full automatic Sliced File • Post-treatment : Cleaning, sand blasting, coating, finishing Σ 2D layers © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011 5 CENG
  • 6. Rapid Prototyping vs Additive Manufacturing Rapid Prototyping Additive Manufacturing • Stereolithography • Electron Beam Melting • Bi-material 3D Printing • Selective Laser Melting • 3D Printing of wax • Laser Cladding • Selective Laser Sintering • Hybrids of Stereolithography • 3D Printing of polymers / plaster Functional parts Visual Final parts parts © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011 6 CENG
  • 7. Sirris ADD capacities & competencies SIRRIS – World leader: Most complete machine park • 15 engineers and technicians • Two locations: Liège (10 p.) and Charleroi (5 p.) Rapid Prototyping / Tooling / Manufacturing • Stereolithography (normal & hi-res) • Paste polymerisation for ceramics and metals (Optoform) • 3D Printing of plaster and metal powder • Laser sintering of polymeric powder (PA,…): P360 – P390 • Objet Connex 500: bi-material • Laser sintering of metal powder (parts and mould inserts) • Electron Beam Melting (Arcam A2) • 3D Printing of wax (Thermojet) • Vacuum Casting of Alu, Bronze, Zamak • Laser Cladding (EasyClad) • Selective Laser melting (MTT) © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011 7 CENG
  • 8. Benefits of Additive Manufacturing @ Medical field • Evolution of medical imagery technology => Easy access to 3D world ! Need for custom implants ! Every human is different (anatomy) Need of flexibility, complex structures and fast response for surgery! Very small or even standard (large) manufacturing series possible © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011 8 CENG
  • 9. The utility of Additive Manufacturing technologies in the medical field Next generation pre-operative manufactured implants: • Custom implant manufacture : • CT-Scan • CAD File of the patient is produced • Engineer + Surgeon 3D implant approved • FEM analysis (when needed) • Custom manufacturing (low cost) • Surgery • Follow up [Sirris ADD] [Sirris ADD] [Sirris ADD] © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011 9 CENG
  • 10. ADD capacities & competencies Medical Additive Manufacturing Software: • Materialise: Mimics • Materialise: 3-matic • Marcam: Autofab • Able Software Corp: 3D Doctor • Medicim: Maxilim • ProEngineer • New: Lenexa: Analyze • New: Brisbane: Anatomics • (…) [Mimics & 3-matic - Materialise] © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 25/11/2011 10 CENG
  • 11. Indirect Manufacturing: Optoform process le centre collectif de l’industrie technologique belge CENG
  • 12. Optoform Generalities: • Commercially not available any more • Flexible technology (hybrid SLA): •Development of very different materials • Possible materials: •Soft, hard, metallic and ceramic • ISO 13485 certified @ Sirris Fabrication steps: • Preparation and fabrication of the bulk material • CAO / CAD File processing • Automated process manufacturing • Cleaning and recycling of the non-used material • Debinding & Sintering process [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 12 CENG
  • 13. Optoform Features: • Layer thickness: 20 - 200µm • Argon laser 400-800mWatt at 351nm and 365nm • Max. Size: 250-350-500mm • Several building plates with variable sizes well suited to small parts and expensive materials • Supports needed Material Requirements: • Composition : Resin+ Fillers (20% to 70% Vol.) + Photo-initiator + Wetting agent + rheological/ thixotropic Agent • Consistency : Firmness of a toothpaste (Bingham’s model) • Good Lifetime : the filler should not deposit sediment • No UV absorption by the filler ↔ Layer thickness • Support removal & cleaning: not always easy (isopropanol, water,…) © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 13 CENG
  • 14. Optoform [Sirris ADD] [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 14 CENG
  • 15. Optoform Materials: • Alumina • Alumina with 8% of nano Zirconia • Hydroxyapatite • α & β Tri-calciumphosphate • Zirconia • SiC [Sirris ADD] • Stainless steel • Titanium [Sirris ADD] • Ceramics & metals need a post-process of debinding & sintering [Sirris ADD] [Sirris ADD] [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 15 CENG
  • 16. Optoform & medical field: CASE STUDIES Ongoing statuts: • Porous scaffolds in Hydroxyapatite Ca5(PO4)3(OH) • Diameter ~= 10mm • Macro-porosity ~= 0,5mm • Tests various scaffold structures for bone integration • In vivo testing (rabbits & rats) • Field: Spinal implants & Maxillofacial Surgery • Spinal implants (HAP/TCP): 10.000 manufactured so far (November 2011) [Sirris ADD] [Sirris ADD] [Sirris ADD] [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 16 CENG
  • 17. Optoform & medical field: CASE STUDIES [Sirris ADD] [Sirris ADD] 0,5mm [Sirris ADD] [Sirris ADD] [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 17 CENG
  • 18. Optoform & medical field: CASE STUDIES [Sirris ADD] [Sirris ADD] © Sirris | www.sirris.be | info@sirris.be | 06/12/2011 18 CENG
  • 19. Sirris Additive Manufacturing: Contact Carsten ENGEL R&D Biomedical Engineer Mail: carsten.engel@sirris.be Mobile: +32 498 91 94 50 Skype: Carsten-Engel SIRRIS Rue Auguste Piccard, 20 B-6041 GOSSELIES BELGIUM http://www.sirris.be © sirris 2011 Charleroi | www.sirris.be | info@sirris.be | 06/12/2011 19 CENG