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GENOMICS
                      APPLICATIONS
                       PLATFORM




Friday, 27 April 12
GENESTACK PLATFORM
                  OBJECTIVE        universal genomics
                                 applications platform

                               existing tool integration
                  REASON
                              & new tool development

                                     provide full set of
                  APPROACH
                                       building blocks


Friday, 27 April 12
GENESTACK PLATFORM
                      Sharing      Public data



     Security                        Applications



                        HPC        Private data


Friday, 27 April 12
GENESTACK PLATFORM
                      DATA         private & secure
                                            sharing
                                   free public data
                               format-independent
                                 custom data types




Friday, 27 April 12
GENESTACK PLATFORM



                      efficient computation      APPLICATIONS
                      unified user interface
                      scriptable
                      trusted
                      application SDK
Friday, 27 April 12
Friday, 27 April 12
GENESTACK PLATFORM
                           FOR DEVELOPERS


        SDK & tooling
        Data and applications store
        Security audit/testing




Friday, 27 April 12
GENESTACK SERVICE
                           PUBLIC DATA

       Meta-curation
       Quality control
       NGS tools
       Free access



Friday, 27 April 12
GENESTACK SERVICE
                        END-TO-END SEQUENCING


                                        NGS service partners
                                        Data direct to cloud
                                          Curation and apps




Friday, 27 April 12
GENESTACK SERVICE
                         CLOUD DEPLOYMENT


        Cost-effective, secure
        Offsite backup
        Long term archival




Friday, 27 April 12
Friday, 27 April 12
Genestack Limited, Salisbury      Telephone +447990705531,             Registered in England
                                                                         and Wales Company
  House, Station Road, Cambridge,   Email: info@genestack.com,           No. 7778793


 GENESTACK
  CB1 2LA, United Kingdom           Twitter: @genestackltd


  www.genestack.com

 GENESTACK
 www.genestack.com

 GENOMICS                                                Universal genomics data platform. Secure hosting and team sharing of Big
                                                         Data genomics experiments. Bioinformatics applications ecosystem in the

 OPERATING
 GENOMICS                                              Universal genomics data platform. Securedata from public repositories. Data
                                                        cloud. Free access to curated genomic hosting and team sharing of Big
                                                       Data genomics application development. End-to-end sequencing service.
                                                        curation and experiments. Bioinformatics applications ecosystem in the
 SYSTEM
 OPERATING                                             cloud. Free access to curated genomic data from public repositories. Data
                                                         Applications SDK & marketplace. Fixed monthly subscription.
                                                       curation and application development. End-to-end sequencing service.
 SYSTEM                                                Applications SDK & marketplace. Fixed monthly subscription.


  Solutions to Six Problems With Genomic Data and Applications in the Enterprise

 Solutions to Six Problems With Genomic Data and Applications in the Enterprise
  1. Managing Genomic Data Storage Costs                                  Interesting: NGS produces files hundreds of gigabytes
                                                                          in size; encrypting/decrypting them is slow and CPU-
  Problem: Sequencing gets cheaper per genome,
                                                                          intensive, while bioinformatics tools can take hours or
 1. Managing Genomic Dataper dollar, but data storage
  producing more gigabases Storage Costs                               Interesting: NGS produces files hundreds of gigabytes
                                                                          days to run. We have thought of ways to maintain
  and processing costs are in fact growing. In-house                   in size; encrypting/decrypting them is slow and CPU-
 Problem: Sequencing gets cheaper per genome,                             security even for such cases.
                                                                       intensive, while bioinformatics tools can take hours or
 producing more gigabases pertake large capital
  storage and cluster solutions dollar, but data storage
  expenditures and big operating costs.                                days Using Public Data with Proprietary Kapushesky, CEO
                                                                                                         Misha Data Cost-
                                                                         3. to run. We have thought of ways to maintain
 and processing costs are in fact growing. In-house
                                                                       security even for such cases.
                                                                         effectively                     misha@genestack.com
 storage and cluster solutions take large capital
  Solution: We offer Want to taketo
 Launch fall 2012. a operating costs. manage your data
 expenditures and big
                      scalable way part in our early access programme?                         Twitter @genestackltd
                                                             3. Using Public Data with Proprietary Data Cost-
  storage and processing costs on our cloud-based                        Problem: To use data from 1000 Genomes, GEO, Ensembl
Friday, 27 April 12                                                    effectively

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Genestack Genomics Applications Platform

  • 1. GENOMICS APPLICATIONS PLATFORM Friday, 27 April 12
  • 2. GENESTACK PLATFORM OBJECTIVE universal genomics applications platform existing tool integration REASON & new tool development provide full set of APPROACH building blocks Friday, 27 April 12
  • 3. GENESTACK PLATFORM Sharing Public data Security Applications HPC Private data Friday, 27 April 12
  • 4. GENESTACK PLATFORM DATA private & secure sharing free public data format-independent custom data types Friday, 27 April 12
  • 5. GENESTACK PLATFORM efficient computation APPLICATIONS unified user interface scriptable trusted application SDK Friday, 27 April 12
  • 7. GENESTACK PLATFORM FOR DEVELOPERS SDK & tooling Data and applications store Security audit/testing Friday, 27 April 12
  • 8. GENESTACK SERVICE PUBLIC DATA Meta-curation Quality control NGS tools Free access Friday, 27 April 12
  • 9. GENESTACK SERVICE END-TO-END SEQUENCING NGS service partners Data direct to cloud Curation and apps Friday, 27 April 12
  • 10. GENESTACK SERVICE CLOUD DEPLOYMENT Cost-effective, secure Offsite backup Long term archival Friday, 27 April 12
  • 12. Genestack Limited, Salisbury Telephone +447990705531, Registered in England and Wales Company House, Station Road, Cambridge, Email: info@genestack.com, No. 7778793 GENESTACK CB1 2LA, United Kingdom Twitter: @genestackltd www.genestack.com GENESTACK www.genestack.com GENOMICS Universal genomics data platform. Secure hosting and team sharing of Big Data genomics experiments. Bioinformatics applications ecosystem in the OPERATING GENOMICS Universal genomics data platform. Securedata from public repositories. Data cloud. Free access to curated genomic hosting and team sharing of Big Data genomics application development. End-to-end sequencing service. curation and experiments. Bioinformatics applications ecosystem in the SYSTEM OPERATING cloud. Free access to curated genomic data from public repositories. Data Applications SDK & marketplace. Fixed monthly subscription. curation and application development. End-to-end sequencing service. SYSTEM Applications SDK & marketplace. Fixed monthly subscription. Solutions to Six Problems With Genomic Data and Applications in the Enterprise Solutions to Six Problems With Genomic Data and Applications in the Enterprise 1. Managing Genomic Data Storage Costs Interesting: NGS produces files hundreds of gigabytes in size; encrypting/decrypting them is slow and CPU- Problem: Sequencing gets cheaper per genome, intensive, while bioinformatics tools can take hours or 1. Managing Genomic Dataper dollar, but data storage producing more gigabases Storage Costs Interesting: NGS produces files hundreds of gigabytes days to run. We have thought of ways to maintain and processing costs are in fact growing. In-house in size; encrypting/decrypting them is slow and CPU- Problem: Sequencing gets cheaper per genome, security even for such cases. intensive, while bioinformatics tools can take hours or producing more gigabases pertake large capital storage and cluster solutions dollar, but data storage expenditures and big operating costs. days Using Public Data with Proprietary Kapushesky, CEO Misha Data Cost- 3. to run. We have thought of ways to maintain and processing costs are in fact growing. In-house security even for such cases. effectively misha@genestack.com storage and cluster solutions take large capital Solution: We offer Want to taketo Launch fall 2012. a operating costs. manage your data expenditures and big scalable way part in our early access programme? Twitter @genestackltd 3. Using Public Data with Proprietary Data Cost- storage and processing costs on our cloud-based Problem: To use data from 1000 Genomes, GEO, Ensembl Friday, 27 April 12 effectively