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Genes and Gene Expression   Macromolecules and Genetic Information
Macromolecular Synthesis ,[object Object],[object Object],[object Object],[object Object]
 
o 3 prime 5 prime
DNA  Structure : The Double Helix ,[object Object]
Complementary Strands and Bases ,[object Object],[object Object],[object Object],[object Object]
[object Object]
 
[object Object]
DNA Structure: Supercoiling ,[object Object],[object Object],[object Object]
 
Extranuclear DNA ,[object Object],[object Object],[object Object],[object Object]
Replication ,[object Object],[object Object],[object Object]
[object Object]
 
DNA Replication: The Replication Fork   ,[object Object],[object Object],[object Object],[object Object]
 
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Leading and Lagging DNA Strands
[object Object],[object Object],[object Object],[object Object]
Okazaki Fragments ,[object Object],[object Object],[object Object],3’
 
P adenine P cytosine guanine P P thymine guanine P P 5’ Okazaki Fragments P adenine P cytosine thymine 3’ P thymine P guanine adenine 3’ P thymine P guanine guanine 3’ 5’ P P thymine P guanine guanine 3’ 5’ P
Tools for Manipulating DNA,    Restriction Enzymes and Hybridization
Restriction Enzyme Digestion  ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],The Polymerase Chain Reaction (PCR)
a
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Transfer of Genetic Information
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Three Types of RNA
[object Object],[object Object],[object Object],Transcription
 
Elongation of RNA Transcript
Terminators ,[object Object],[object Object]
The Unit of Transcription ,[object Object],[object Object],[object Object]
 
Codons ,[object Object],[object Object],[object Object]
The Genetic Code  The codon AUG specifies the amino acid Methionine which always begins a protein molecule. There is no amino acid associated with the codons UAA, UAG, and UGA. These codons always end a protein molecule. Note: there are 6 codons which specify Leucine and Serine, only a single codon for Methionine and Tryptophan. All the other amino acids have at least 2 codons which specify them. First Letter   Middle Letter = U   Middle Letter = C   Middle Letter = A   Middle   Letter = G   Last Letter   U UUU - Phenylalanine  UCU - Serine  UAU - Tyrosine  UGU - Cysteine  U U UUC - Phenylalanine  UCC - Serine  UAC - Tyrosine  UGC - Cysteine  C U UUA - Leucine  UCA - Serine  UAA -  STOP   UGA -  STOP   A U UUG - Leucine  UCG - Serine  UAG -  STOP   UGG - Tryptophan  G C CUU - Leucine  CCU - Proline  CAU - Histidine  CGU - Argenine  U C CUC - Leucine  CCC - Proline  CAC - Histidine  CGC - Argenine  C C CUA - Leucine  CCA - Proline  CAA - Glutamine  CGA - Argenine  A C CUG - Leucine  CCG - Proline  CAG - Glutamine  CGG - Argenine  G A AUU - Isoleucine  ACU - Threonine  AAU - Asparagine  AGU - Serine  U A AUC - Isoleucine  ACC - Threonine  AAC - Asparagine  AGC - Serine  C A AUA - Isoleucine  ACA - Threonine  AAA - Lysine  AGA - Argenine  A A AUG - Methionine  - START   ACG - Threonine  AAG - Lysine  AGG - Argenine  G G GUU - Valine  GCU - Alanine  GAU - Aspartate  GGU - Glycine  U G GUC - Valine  GCC - Alanine  GAC - Aspartate  GGC - Glycine  C G GUA - Valine  GCA - Alanine  GAA - Glutamine  GGA - Glycine  A G GUG - Valine  GCG - Alanine  GAG - Glutamine  GGG - Glycine  G
 
 
Nonsense Codons ,[object Object],[object Object],[object Object]
 
Transfer RNA ,[object Object],[object Object]
tRNA
Ribosome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Initiation ,[object Object],[object Object]
 
[object Object],[object Object],[object Object],Translation-Elongation
 
[object Object]
Folding and Secreting  Proteins ,[object Object],[object Object]
Moving through Membrane ,[object Object],[object Object],[object Object],[object Object]

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chapter 7

  • 1. Genes and Gene Expression  Macromolecules and Genetic Information
  • 2.
  • 3.  
  • 4. o 3 prime 5 prime
  • 5.
  • 6.
  • 7.
  • 8.  
  • 9.
  • 10.
  • 11.  
  • 12.
  • 13.
  • 14.
  • 15.  
  • 16.
  • 17.  
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.  
  • 24. P adenine P cytosine guanine P P thymine guanine P P 5’ Okazaki Fragments P adenine P cytosine thymine 3’ P thymine P guanine adenine 3’ P thymine P guanine guanine 3’ 5’ P P thymine P guanine guanine 3’ 5’ P
  • 25. Tools for Manipulating DNA,   Restriction Enzymes and Hybridization
  • 26.
  • 27.
  • 28. a
  • 29.  
  • 30.
  • 31.
  • 32.
  • 33.  
  • 34. Elongation of RNA Transcript
  • 35.
  • 36.
  • 37.  
  • 38.
  • 39. The Genetic Code The codon AUG specifies the amino acid Methionine which always begins a protein molecule. There is no amino acid associated with the codons UAA, UAG, and UGA. These codons always end a protein molecule. Note: there are 6 codons which specify Leucine and Serine, only a single codon for Methionine and Tryptophan. All the other amino acids have at least 2 codons which specify them. First Letter Middle Letter = U Middle Letter = C Middle Letter = A Middle Letter = G Last Letter U UUU - Phenylalanine UCU - Serine UAU - Tyrosine UGU - Cysteine U U UUC - Phenylalanine UCC - Serine UAC - Tyrosine UGC - Cysteine C U UUA - Leucine UCA - Serine UAA - STOP UGA - STOP A U UUG - Leucine UCG - Serine UAG - STOP UGG - Tryptophan G C CUU - Leucine CCU - Proline CAU - Histidine CGU - Argenine U C CUC - Leucine CCC - Proline CAC - Histidine CGC - Argenine C C CUA - Leucine CCA - Proline CAA - Glutamine CGA - Argenine A C CUG - Leucine CCG - Proline CAG - Glutamine CGG - Argenine G A AUU - Isoleucine ACU - Threonine AAU - Asparagine AGU - Serine U A AUC - Isoleucine ACC - Threonine AAC - Asparagine AGC - Serine C A AUA - Isoleucine ACA - Threonine AAA - Lysine AGA - Argenine A A AUG - Methionine - START ACG - Threonine AAG - Lysine AGG - Argenine G G GUU - Valine GCU - Alanine GAU - Aspartate GGU - Glycine U G GUC - Valine GCC - Alanine GAC - Aspartate GGC - Glycine C G GUA - Valine GCA - Alanine GAA - Glutamine GGA - Glycine A G GUG - Valine GCG - Alanine GAG - Glutamine GGG - Glycine G
  • 40.  
  • 41.  
  • 42.
  • 43.  
  • 44.
  • 45. tRNA
  • 46.
  • 47.
  • 48.
  • 49.  
  • 50.
  • 51.  
  • 52.
  • 53.
  • 54.