Non invasive detection of microaneurisms using the rtx1

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Imagine Eyes

Santé Santé & Médecine Technologie

Non invasive detection of
microaneurisms using the rtx1
M. Paques
Clinical Investigation Center 503, INSERM,
Quinze-Vingts National Eye Hospital, Paris, France
rtx1 adaptive optics retinal camera
Case report
Diabetic retinopathy

Imagine Eyes rtx1 case report -- diabetic retinopathy
Conventional angiography
Patient with diabetic
retinopathy
Conventional fluorescein
angiography shows
multiple micro-
aneurysms.
Fluorescein
angiography

Imagine Eyes rtx1 case report -- diabetic retinopathy
Adaptive optics examination
Fluorescein
angiography
Adaptive optics reveals the
same microaneurisms,
without the need for
injecting fluorescein
AO (rtx1)

Imagine Eyes rtx1 case report -- diabetic retinopathy
Adaptive optics examination
Adaptive optics detects the
same microaneurisms,
without the need for
injecting fluorescein.
Central reflex indicates
aneurisms of spherical
shape
Magnified
AO (rtx1)

Imagine Eyes rtx1 case report -- diabetic retinopathy
Conclusion
• Adaptive optics imaging enables visualizing
microscopic aneurisms in diabetic retinopathy
• Unlike fluorescein angiography, the rtx1 examination
is non invasive as it does not require the injection of
a fluorescent agent
• See also:
M. Lombardo, M. Parravano, S. Serrao, P. Ducoli, M. Stirpe, and G. Lombardo,
"Analysis of retinal capillaries in patients with type 1 diabetes and nonproliferative
diabetic retinopathy using adaptive optics imaging" Retina, vol. 33, no. 8, pp. 1630-
1639, Sep.2013

Non invasive detection of microaneurisms using the rtx1

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