21. identify FLCs at a minimum concentration of 100-150mg/l. Insufficient to identify non secretory or oligo-secretory myeloma
22. Technique uses purified polyclonal antibodies against free k and λ light chains which are precoated to latex particles and then analyzed by nephlometric assay for quantification. Permits detection of light chain to a level of 2-4mg/l.
32. Pts got PD in control and HD in PPx group Eleven patients were randomized to receive PLEX. They noted no differences in the overall renal recovery rate however, in a subgroup analysis of the dialysis patients, renal recovery occurred only in those who received PLEX. Small study. compromised by the use of a composite outcome which disadvantaged PLEX because patient who died with improved renal function and those with eGFR <30 were considered failures. the renal pathology was not verified due to the low biopsy rate. Finally, no method was employed to assess the adequacy of treatment.
33.
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42. Mesangial & Cap loops amyloid deposits. Arteriolar wall with amyloid.