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SYNAPSES AND DRUGS
What is a synapse? ,[object Object],[object Object],[object Object]
A Synapse ,[object Object],[object Object]
Neurotransmitter ,[object Object],[object Object]
Cholinergic Synapses ,[object Object],[object Object],[object Object],[object Object]
What happens at a cholinergic synapse?  Stage 1 ,[object Object]
What happens at a cholinergic synapse?  Stage 2 ,[object Object]
What happens at a cholinergic synapse?  Stage 3 ,[object Object]
What happens at a cholinergic synapse?  Stage 4 ,[object Object]
What happens at a cholinergic synapse?  Stage 5 ,[object Object]
Neuromuscular Junctions ,[object Object]
Drugs ,[object Object],[object Object],[object Object]
Various effects of drugs on synapses:   DRUG ACTION EFFECT     Mimic a neurotransmitter Switch on a synapse Stimulate the release of a neurotransmitter Switch on a synapse Open a neuroreceptor channel Switch on a synapse Block a neuroreceptor channel Switch off a synapse Inhibit the breakdown enzyme Switch on a synapse Inhibit the Na + K + ATPase pump Stop action potentials Block the Na +  or K +  channels Stop action potentials
Effect of nicotine and atropine
Summary ,[object Object],[object Object],[object Object],[object Object]

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Synapses and drugs

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  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. Various effects of drugs on synapses:   DRUG ACTION EFFECT     Mimic a neurotransmitter Switch on a synapse Stimulate the release of a neurotransmitter Switch on a synapse Open a neuroreceptor channel Switch on a synapse Block a neuroreceptor channel Switch off a synapse Inhibit the breakdown enzyme Switch on a synapse Inhibit the Na + K + ATPase pump Stop action potentials Block the Na + or K + channels Stop action potentials
  • 14. Effect of nicotine and atropine
  • 15.