Arrhythmogenic right ventricular 2003

Arrhythmogenic right ventricular dysplasia Kumaresan Dr. Kim Vaiphei

Introduction ,[object Object],[object Object],[object Object]

Incidence/prevalence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pathophysiology ,[object Object],[object Object],[object Object]

Genetic factors ,[object Object],[object Object],[object Object],[object Object],[object Object]

Chromosomal loci and causal genes Chromosome Symbol Protein Function ARVD/C 1 14q24.3 TGF  3 TGF  3 Mitotic factor ARVD/C 2 14q42.2 RYR 2 Ryanodine receptor 2 Ca channel ARVD/C 3 1q12 ARVD/C 4 2q32.1 ARVD/C 5 3p23 ARVD/C 6 10p12 ARVD/C 7 10q22 ARVD/C 8 6p24 DSP Desmoplakin Desmosomes ARVD/C 9 12p11 PKP 2 Plakoglobin 2 Desmosomes 18q12.1 DSG 2 Desmoglein 2 Desmosomes Naxos disease 17q21 JUP Plakoglobin Desmosomes

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Autosomal recessive variant of ARVD/C ,[object Object],[object Object],[object Object],[object Object]

Etiopathogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Gross ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Histology ,[object Object],[object Object],[object Object]

Fatty infiltration ,[object Object],[object Object],[object Object],[object Object],[object Object]

Fibro-fatty infiltration ,[object Object],[object Object],[object Object],[object Object],[object Object]

Phases of ARVD ,[object Object],[object Object],[object Object]

Clinical presentation ,[object Object],[object Object],[object Object],[object Object]

Diagnosis ,[object Object],[object Object]

Diagnosis ,[object Object],[object Object],[object Object]

Diagnostic Criteria ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ECG ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RV contrast angiography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Echocardiography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Uhl’s anomaly ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pathology ,[object Object],[object Object],[object Object]

Exercise and ventricular arrhythmias ,[object Object],[object Object],[object Object],[object Object],[object Object]

Natural history ,[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]

Arrhythmogenic right ventricular 2003

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Arrhythmogenic right ventricular 2003

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