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Chest Pain
Causes of Chest Pain
• Central chest pain
• Peripheral chest pain
Central chest pain

• Anxiety emotion (may also cause peripheral
    chest pain)
•    Cardiac cause
       - Myocardial ischaemia (angina)
       - Myocardial infarction
       - Myocarditis
       - Pericarditis
       - Mitral valve prolapse syndrome
• Aortic
     -Aortic dissection
      -Aortic Aneurysm
• oesophageal
     - Oesophagitis
     - Oesophageal spasm
     - Mallory-weiss syndrome
• Massive pulmonary embolism
• Mediastinal
     - Tracheitis
     - malignancy
Pheripheral chest pain
• lungs / pleura.
     - pulmonary
       infarct        -   malignancy
     - pneumonia      -   TB
     - pneumothorax   -   connective tissue
                          d/s
• Musculoskeletal
 - osteoarthritis
 - Rib fracture/ injury
 - intercostal m/s injury
 - costochondritis (Tietze's syndrome)
 - Epidemic myalgia (Bornholm d/s)
• Neurologial
 - PID
 - Herpes zoster
 - Thoraeic outlet syndrome
Enquire about chest pain


•   Site of origin of pain
•   Duration
•   Radiation
•   Character of the pain & severity
•   Pattern of onset
•   Aggravating factor relieving factor
•   Associated features
Site of origin of pain

Angina - Pain is characteristics central &
           retrosternal diffuse
        - because of the derivation of nerve
           supply to the heart & mediasinum
Pleural or lung d/s musculo skeletal and
  Anxiety
        - Peripheral localised
Radiation
ischaemic pain - radiate to neck, jaw &
                upper & even lower arms
              - sometime only at the site of
              radiation or in the back
Non Cardiac chest pain
              - other or no radiation
Character

Ishaemic cardiac Pain
• typically dull, constricting choking or heavy
  & is usually described as squeezing,
  crushing, burning or aching .
• The sensation can be described as
  breathlessness or like indigestion
• patient typicaly use characteristic hand
  gesture (eg. open hand or clenched fist)
  when describing ischaemic pain.

Non cardiac pain
 - sharp , stabbing , pricking or knife-like
Aggravating Factor
Angina    - Exertion
          - Emotion, excitement
          - Cold weather
          - Exercise after meal.
Pleural, pericardial pain
          - breathing coughing or movement
Musculoskeletal pain
          - Specific movement
            (bending, stretching, turning)
Relieving Factor

Angina   - Rest
         - Glyceryl trinitrate
         - warm up before exercise
Non cardiac pain
         - Not relieved by rest
         - Slow or no response to nitrate
Pattern of onset

MI   - typically take several minutes or even
       longer to develop.
Angina -build up gradually in proportion
           to the intensity of exertion
Aortic dissection, PE, Pneumothorax
           -very sudden onset
Associated features
MI, PE, Aortic dissection
          - Accompanied by autonomic
           disturbance including sweating,
            nausea and vomiting
MI,Angina
          - Breathlessness due to
            pulmonary congestion arising
            from transient ischaemic left
      ventricular dysfunction
Non cardiac pain
          - Respiratory , GI, locomotor or
            psychological
Severity Of Angina

• Canadian Cardiovascular Society:
 functional classification of stable angina
Grade 1 - Ordinary physical activity such
         as walking and climbing stairs,
         does not cause angina. Angina
         with strenous or rapid or
         prolonged exertion at work or
         recreation
Grade 2 - Slight limitation of ordinary activity.
               Walking or climbing stairs rapidly,
               walking uphill, walking or stair
               climbing after meals in cold ,in
 wind, or           when under emotional
 stress, or only          during the few hours
 after awakening.
Grade 3 - Marked limitation of ordinary
          physical activity . Walking
    one to two blocks on the level
    and climbing less than one
    flight in normal condition.
• Grade 4 – Inability to carry on any
        physical activity without
       discomfort anginal
       syndrome may be present
       at rest.
Questions –To assess the severity of
          angina
• How far can you walk on the flat before
 experiencing discomfort ?
• Do you get discomfort climbing stairs or
 hills ?
• Do you experience discomfort gardening,
 making the bed or during other household
 chores?
• Does sexual intercourse produce
 discomfort ?
• Is the discomfort influenced by
 meals ?
• Is it influenced by cold weather ?
Types of cardiac pain
Type                Cause                         Characteristic


Angina              Coronary stenosis (rarely    Precipitated by
                    aortic stenosis hypertrophic exertion, eased by rest
                    cardiomyopathy )             Characteristic
                                                 distribution
Myocardial          Coronary occlusion           Similar sites to
infarct                                          angina ,more severe
                                                 ,persists at rest.
Pericarditic pain   Pericarditis                  Sharp, raw or stabbing
                                                  Varies with movement
                                                  or breathing
Aortic pain         Dissection of the aorta       Severe ,sudden onset ,
                                                  radiates to the back
Differential diagnosis
Psycological aspects of chest
  pain
• very common
• considered if there are features of
  anxiety or neurosis
• lacks a predictable relationship with
  exercise
Psycological aspects of chest
pain

• Psychological and organic features can be
  coexist
• responsible for the death of close friend or
  relative
• Anxiety may amplify the effects of organic
  disease (create a confusing picture)
Musculosketal Chest Pain
• Common problem
• Very variable in site and intensity
• Pain may vary with posture or
  movement of the upper body
• Sometimes accompanied by local
  tenderness over a rib or costal
  cartilage
Musculosketal Chest Pain


• Numerous causes of chest wall pain
       - arthritis
       - Costochondritis
       - intercostal muscle injury
       - coxsackie viral infection
    (epidemic      myalgia or Bornholm
    disease)
•   Many minor soft tissue injury are
    related to everyday activities such as
Differential diagnosis:angina vs
 oesophageal pain
Angina                 Oesophageal pain
• Usually precipitated • Canbe worsened by
  by exertion            exertion, but often
                         present at other times
                       • Not rapidly relieved
• Rapidly relieved by    by rest
  rest
                       • Retrosternal or
• Restrosternal and      epigastric, sometimes
  radiates to arm and
                         radiates to arm or
  jaw
                         back
Differential diagnosis:angina vs
oesophageal pain
Angina                  Oesophageal pain
• seldom wakes          • Often wakes patient
  patient from sleep      from sleep
• No relation to        • Sometimes related
  heartburn (but          to heartbum
  patients often have
 'wind')
• Rapidly relieved by   • Often relieved by
 nitrates                 nitrates
• Typical duration      • Variable duration
 2-10 minutes
Differential diagnosis:angina vs
   myocardial infarction
Angina                         Myocardial infarction
Site: retrosternal, radiates   As for angina
to arm, epigastrium, neck
Precipitated by exercise or    Often no obvious
emotion                        precipitant
Relieved by rest, nitrates     Not relieved by rest,
                               nitrates
Differential diagnosis:angina vs
 myocardial infarction
Angina                Myocardial infarction
• Mild/moderate       • Usually severe (may be
  severity              silent')
• Anxiety absent or   • Severe
  mild
• No increased
  sympathetic         • Increased sympathetic
                       activity
  activation
• No nausea or
  vomiting            • Nausea and vomiting are
Characteristics of percarditic pain

Site         • -Retrosternal, may radiate
               to left shoulder or back
Prodrome     • -May be preceded by a viral
               illness
Onset        • -No obvious initial
               recipitating factor; tends to
               fluctuate in intensity
Characteristics of percarditic pain
Nature                • May be stabbing or
                       'raw'-'like sandpaper'.
                         Often described as
                       sharp,rarely as tight
                      or heavy
Made worse by         • Changes in posture,
                      respiration
Helped by
                      • Analgesics,
                         especially
Accompanied
 by                     NSAIDs
                      • Pericardial rub
Characteristics of pain caused by
dissection of aortic aneurysm
  Site          • Often first felt between
                  shoulder blades, and/or
                  retrosternally
  Onset         • Usually sudden


  Nature
                • Very severe pain, often
                  described as 'tearing' in
                  nature
Characteristics of pain caused by
 dissection of aortic aneurysm
Relieved by      • Tends to persist. Patients
                   often restless with pain
Accompanied by   • Hypertension, asymmetric
                   pulses, unexpected
                   bradycardia, early diastolic
                   murmur. syncope, focal
                   neurological symptoms and
                   signs
Central Chest Pain Causes Guide

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Central Chest Pain Causes Guide

  • 2. Causes of Chest Pain • Central chest pain • Peripheral chest pain
  • 3. Central chest pain • Anxiety emotion (may also cause peripheral chest pain) • Cardiac cause - Myocardial ischaemia (angina) - Myocardial infarction - Myocarditis - Pericarditis - Mitral valve prolapse syndrome
  • 4. • Aortic -Aortic dissection -Aortic Aneurysm • oesophageal - Oesophagitis - Oesophageal spasm - Mallory-weiss syndrome • Massive pulmonary embolism • Mediastinal - Tracheitis - malignancy
  • 5. Pheripheral chest pain • lungs / pleura. - pulmonary infarct - malignancy - pneumonia - TB - pneumothorax - connective tissue d/s
  • 6. • Musculoskeletal - osteoarthritis - Rib fracture/ injury - intercostal m/s injury - costochondritis (Tietze's syndrome) - Epidemic myalgia (Bornholm d/s)
  • 7. • Neurologial - PID - Herpes zoster - Thoraeic outlet syndrome
  • 8. Enquire about chest pain • Site of origin of pain • Duration • Radiation • Character of the pain & severity • Pattern of onset • Aggravating factor relieving factor • Associated features
  • 9. Site of origin of pain Angina - Pain is characteristics central & retrosternal diffuse - because of the derivation of nerve supply to the heart & mediasinum Pleural or lung d/s musculo skeletal and Anxiety - Peripheral localised
  • 10. Radiation ischaemic pain - radiate to neck, jaw & upper & even lower arms - sometime only at the site of radiation or in the back Non Cardiac chest pain - other or no radiation
  • 11. Character Ishaemic cardiac Pain • typically dull, constricting choking or heavy & is usually described as squeezing, crushing, burning or aching . • The sensation can be described as breathlessness or like indigestion
  • 12. • patient typicaly use characteristic hand gesture (eg. open hand or clenched fist) when describing ischaemic pain. Non cardiac pain - sharp , stabbing , pricking or knife-like
  • 13. Aggravating Factor Angina - Exertion - Emotion, excitement - Cold weather - Exercise after meal. Pleural, pericardial pain - breathing coughing or movement Musculoskeletal pain - Specific movement (bending, stretching, turning)
  • 14. Relieving Factor Angina - Rest - Glyceryl trinitrate - warm up before exercise Non cardiac pain - Not relieved by rest - Slow or no response to nitrate
  • 15. Pattern of onset MI - typically take several minutes or even longer to develop. Angina -build up gradually in proportion to the intensity of exertion Aortic dissection, PE, Pneumothorax -very sudden onset
  • 16. Associated features MI, PE, Aortic dissection - Accompanied by autonomic disturbance including sweating, nausea and vomiting MI,Angina - Breathlessness due to pulmonary congestion arising from transient ischaemic left ventricular dysfunction Non cardiac pain - Respiratory , GI, locomotor or psychological
  • 17. Severity Of Angina • Canadian Cardiovascular Society: functional classification of stable angina Grade 1 - Ordinary physical activity such as walking and climbing stairs, does not cause angina. Angina with strenous or rapid or prolonged exertion at work or recreation
  • 18. Grade 2 - Slight limitation of ordinary activity. Walking or climbing stairs rapidly, walking uphill, walking or stair climbing after meals in cold ,in wind, or when under emotional stress, or only during the few hours after awakening.
  • 19. Grade 3 - Marked limitation of ordinary physical activity . Walking one to two blocks on the level and climbing less than one flight in normal condition.
  • 20. • Grade 4 – Inability to carry on any physical activity without discomfort anginal syndrome may be present at rest.
  • 21. Questions –To assess the severity of angina • How far can you walk on the flat before experiencing discomfort ? • Do you get discomfort climbing stairs or hills ? • Do you experience discomfort gardening, making the bed or during other household chores?
  • 22. • Does sexual intercourse produce discomfort ? • Is the discomfort influenced by meals ? • Is it influenced by cold weather ?
  • 23. Types of cardiac pain Type Cause Characteristic Angina Coronary stenosis (rarely Precipitated by aortic stenosis hypertrophic exertion, eased by rest cardiomyopathy ) Characteristic distribution Myocardial Coronary occlusion Similar sites to infarct angina ,more severe ,persists at rest. Pericarditic pain Pericarditis Sharp, raw or stabbing Varies with movement or breathing Aortic pain Dissection of the aorta Severe ,sudden onset , radiates to the back
  • 24. Differential diagnosis Psycological aspects of chest pain • very common • considered if there are features of anxiety or neurosis • lacks a predictable relationship with exercise
  • 25. Psycological aspects of chest pain • Psychological and organic features can be coexist • responsible for the death of close friend or relative • Anxiety may amplify the effects of organic disease (create a confusing picture)
  • 26. Musculosketal Chest Pain • Common problem • Very variable in site and intensity • Pain may vary with posture or movement of the upper body • Sometimes accompanied by local tenderness over a rib or costal cartilage
  • 27. Musculosketal Chest Pain • Numerous causes of chest wall pain - arthritis - Costochondritis - intercostal muscle injury - coxsackie viral infection (epidemic myalgia or Bornholm disease) • Many minor soft tissue injury are related to everyday activities such as
  • 28. Differential diagnosis:angina vs oesophageal pain Angina Oesophageal pain • Usually precipitated • Canbe worsened by by exertion exertion, but often present at other times • Not rapidly relieved • Rapidly relieved by by rest rest • Retrosternal or • Restrosternal and epigastric, sometimes radiates to arm and radiates to arm or jaw back
  • 29. Differential diagnosis:angina vs oesophageal pain Angina Oesophageal pain • seldom wakes • Often wakes patient patient from sleep from sleep • No relation to • Sometimes related heartburn (but to heartbum patients often have 'wind') • Rapidly relieved by • Often relieved by nitrates nitrates • Typical duration • Variable duration 2-10 minutes
  • 30. Differential diagnosis:angina vs myocardial infarction Angina Myocardial infarction Site: retrosternal, radiates As for angina to arm, epigastrium, neck Precipitated by exercise or Often no obvious emotion precipitant Relieved by rest, nitrates Not relieved by rest, nitrates
  • 31. Differential diagnosis:angina vs myocardial infarction Angina Myocardial infarction • Mild/moderate • Usually severe (may be severity silent') • Anxiety absent or • Severe mild • No increased sympathetic • Increased sympathetic activity activation • No nausea or vomiting • Nausea and vomiting are
  • 32. Characteristics of percarditic pain Site • -Retrosternal, may radiate to left shoulder or back Prodrome • -May be preceded by a viral illness Onset • -No obvious initial recipitating factor; tends to fluctuate in intensity
  • 33. Characteristics of percarditic pain Nature • May be stabbing or 'raw'-'like sandpaper'. Often described as sharp,rarely as tight or heavy Made worse by • Changes in posture, respiration Helped by • Analgesics, especially Accompanied by NSAIDs • Pericardial rub
  • 34. Characteristics of pain caused by dissection of aortic aneurysm Site • Often first felt between shoulder blades, and/or retrosternally Onset • Usually sudden Nature • Very severe pain, often described as 'tearing' in nature
  • 35. Characteristics of pain caused by dissection of aortic aneurysm Relieved by • Tends to persist. Patients often restless with pain Accompanied by • Hypertension, asymmetric pulses, unexpected bradycardia, early diastolic murmur. syncope, focal neurological symptoms and signs