1. A Paradigm Shift in Healthcare: Changing Business Models and the Impact of Technology Presented By: Reenita Das Senior Vice President, Healthcare Frost & Sullivan

2. A Changing Landscape

3. Global Healthcare Conclusion Emerging Trends and Impact on Technology Setting the Context

4. Paradigm Shift in Healthcare Healthcare industry for the next decade Medicine of the past Medicine of the future

6. Economic Perspective: Healthcare Spending Set to Double By 2050 Healthcare spending will double, claiming 20 – 30% of GDP Public Per Capita Spending – India : $ 12, Vietnam : $ 42

8. Global Healthcare Conclusion Emerging Trends/ Impact on Technology Setting the Context

10. Cancer Treatment Represents the Highest Potential Projected Revenues In 2012 High Revenues Low Revenues Growth Rate (2007-2012) Low High Established Treatments Unmet Needs

11. Cancer Pipeline 2007 – Split by Phase III & I Increasing Focus on Biologics in the Future Cancer Related Drugs Constitute Half of the Current Biotech Pipeline. Phase III: 5-10 years to launch Phase I: 10-15 years to launch Cancer vaccines are an emerging technology that are likely to create the next wave of growth in the biotechnology industry because of better safety profiles and minimal side effects Other: Includes genetic disorders, skin disorders, eye conditions, growth disorders, transplantation Monoclonal Antibodies constitute half of the Phase III biotech pipeline. More Monoclonal Antibodies are likely to reach the market in the next 5-10 years. 2007

12. Diagram Gene Therapy will Drive the Market in the Longer Term. Technologies such as Pervasive computing are Important in Improving the Drug Discovery Process. Defining diseases more accurately and creating healthcare packages for patients with specific disease subtypes. Resulting in Premium Drugs and the launch of health care kiosks offering one-stop-shop services Semi Block Busters, Patent Expiration Strategies Gene Therapy Growth Rate Opportunities Biologics: Targeted Treatment Solutions, Integrated Solutions Gene therapy uses genes to treat or prevent disease. In the future, this technique will allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using drugs or surgery Genomics / Proteomics Cellomics A disease led approach creates a new discovery and development model. Technology will improve the process e.g. making in-life testing more cost efficient. This brings significant changes for pharma companies in terms of time, development costs and success rates to man. More Info Smart Tags Petaflop & Grid computing Future Technology Trends Predictive biosimulation Advanced storage solutions Pervasive computing Web-scale mining

13. New innovations in In Vitro Diagnostics like Mircoarrays and Lab-On-A-Chip have brought a revolution in the field diagnostics. Growth Rate Opportunities Preventive as well as personal care devices and Home/Self therapy devices will have a very high growth rate and opportunities in entire spectrum of the market. Intelligent/Automated devices, Robotic devices for surgery and diagnosis will reshape the modern face of the healthcare sector Tissue generated devices and site-specific drug delivery devices are being developed for more sophisticated healthcare delivery Infection control devices/Wound care Home/Self therapy devices Total disc replacement Robotic devices Advanced In Vitro Diagnostics Virtual reality Intelligent/Automated devices Electrical stimulation Site specific drug delivery Tissue generation devices Upcoming medical device technology platforms Upcoming Technologies in Medical Devices Top-10 Medical device based platforms for the next decade

14. Clinical IT Systems and Electronic Medical Records Represent the Highest Potential in the Future Projected Revenues In 2012 High Revenues Low Revenues Growth Rate (2007-2012) Low High Clinical decision support systems Image management systems EHR / PHR Financial management Resource management Clinical IT solutions EMR Declining market Mature market Emerging market Growing market Patient management systems

16. Global Healthcare Conclusion Emerging Trends and Impact on Technology Setting the Context

18. A modern healthcare system is on the horizon, experiencing a paradigm shift In Nutshell Fragmented Patient Flow Integrated & Automated From ... Invasive Diagnosis & Treatment Less Invasive, Preventative, Image Based Provider Centric Focus Patient Centric Centralized – Hospital Monitor De-Centralized–Shift to Community One Size Fits All Approach Personalized Medicine Therapeutics/Diagnostics/ Devices Tools “ Theranostics” Treating Sickness Objective Preventing Sickness – “Wellness” ...To

19. Reenita Das Senior Vice President Frost and Sullivan [email_address]