Malignant Melanoma

Malignant Melanoma Epidemiology, classification and surgical treatment

Incidence ,[object Object],[object Object],[object Object]

Age and Sex ,[object Object],[object Object],[object Object],[object Object],[object Object]

What’s new? ,[object Object],[object Object],[object Object],[object Object]

Survival ,[object Object],[object Object],[object Object]

Risk factors ,[object Object],[object Object],[object Object],[object Object],[object Object]

Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Biopsy ,[object Object],[object Object],[object Object],[object Object]

Pathological reporting ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clark level of invasion ,[object Object],[object Object],[object Object],[object Object],[object Object]

Breslow level of invasion ,[object Object],[object Object],[object Object],[object Object]

Histogenetic type ,[object Object],[object Object],[object Object],[object Object],[object Object]

Tests ,[object Object],[object Object],[object Object],[object Object]

ELM criteria: Results of 72 melanoma cases TnM: thin melanoma (<0.75 mm); TkM: thick melanoma (>0.75 mm) ELM criterion Present in 41 TnM n. (%) Present in 31 TkM n. (%) Pigment network 39 ( 95 ) 21 (68) Black dots 25 (61) 20 (64) Radial streaming 34 (83) 22 (71) Brown globules 32 (78) 22 (71) Diffuse gray-black blotches 25 (61) 20 (64) Gray-blue areas 10 (24) 29 ( 94 ) White scarlike areas 23 (56) 12 (39) Linear vascular pattern 6 (15) 6 (19) Dotted vascular pattern 1 (2) 14 ( 45 ) Structural asymmetry 31 (76) 27 (87)

Pigmented network + radial streaming Abnormal Vascolar pattern Thin Melanoma Thick Melanoma Gray, Blue, Shadow +

Melanoma Clinic Diagnosis Melanoma < 0,75 mm Excision (1 cm) Melanoma >0,75 mm Excision (2-3 cm) Lymph Node Biopsy Evaluation of Thickness by Epiluminescence Stereomicroscopic    

Classificazione TNM del Melanoma Stadio pT N M Ia Ib pT1 pT2 N0 M0 II pT3 N0 M0 IIIa IIIb pT4 Ogni pT N0 N1,N2 M0 IV Ogni pT Ogni N M1

pT Tumore primitivo ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

N Linfonodi regionali ,[object Object],[object Object],[object Object],[object Object],[object Object]

M Metastasi a distanza ,[object Object],[object Object],[object Object],[object Object],[object Object]

AJCC Staging System for Melanoma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Local excision (based on thickness of tumour) ,[object Object],[object Object],[object Object]

Special locations ,[object Object],[object Object],[object Object]

Regional lymph nodes ,[object Object],[object Object],[object Object]

Sentinel biopsy concept ,[object Object],[object Object],[object Object]

Adjuvant therapy ,[object Object],[object Object],[object Object]

5 year Survival ,[object Object],[object Object],[object Object],[object Object],[object Object]

Recurrences ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Distant metastases ,[object Object],[object Object],[object Object],[object Object],[object Object]

Follow-up ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Malignant Melanoma

Recommandé

Recommandé

Contenu connexe

Tendances

Tendances (20)

Similaire à Malignant Melanoma

Similaire à Malignant Melanoma (20)

Dernier

Dernier (20)

Malignant Melanoma