8. The manifestations of early congenital syphilis most often occur within the first 3 to 7 weeks after birth and result from active, disseminated fetal infection and the subsequent inflammatory response. Hepatosplenomegaly/hepatitis, jaundice, lesions on the skin and/or in the mouth (Fig. 5), rhinitis, inflammation of long bones (osteochondritis, perichondritis), adenopathy, and hematologic disturbances (anemia, thrombocytopenia) are typical early manifestations of congenital syphilis. Low birth weight and failure to thrive also may occur. Necrotizing funisitis--an inflammation of the umbilical cord characterized by spiral stripes of red and blue discoloration resembling a "barber's pole"--is a specific sign of congenital syphilis.[1]