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Syphilis and neurosyphilis 101
T. Pallidum
Stages of syphilis
Primary Syphilis
Secondary syphilis
Tertiary syphilis
Congenital syphilis
The manifestations of early congenital syphilis most often occur within the first 3 to 7 weeks after birth and result from active, disseminated fetal infection and the subsequent inflammatory response. Hepatosplenomegaly/hepatitis, jaundice, lesions on the skin and/or in the mouth (Fig. 5), rhinitis, inflammation of long bones (osteochondritis, perichondritis), adenopathy, and hematologic disturbances (anemia, thrombocytopenia) are typical early manifestations of congenital syphilis. Low birth weight and failure to thrive also may occur. Necrotizing funisitis--an inflammation of the umbilical cord characterized by spiral stripes of red and blue discoloration resembling a "barber's pole"--is a specific sign of congenital syphilis.[1]
Bones in Congenital syphilis
 
Prevalnce rate in PA
types of neurosyphilis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Asymptomatic and meningeal neurosyphilis ,[object Object]
Meningeovascular syphilis ,[object Object]
General Paralysis on Insane ,[object Object]
Common neurological signs ,[object Object]
Signs of tabes dorsalis ,[object Object]
Prognosis of tabes dorsalis ,[object Object]
General paralysis of Insane ,[object Object]
Late stage of General Paralysis ,[object Object]
Neurosyphilis
Meningeal neurosyphilis
Diagnosis of neurosyphilis ,[object Object]
Tests of neurosyphilis ,[object Object],[object Object],[object Object],[object Object],[object Object]
CSF changes in neurosyphilis ,[object Object]
treatment ,[object Object],[object Object]

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