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01
  WINTER


                   2005
                             Circulation
ACLS
  Template




                  Panita Worapratya
            Emergency Department
       Prince of Songkhla University
Effective Chest compression

Goals                          How to achieve

                               Push 100/min
              Push
             hard &            Deep 1/3 of chest wall
              fast

                               Fully recoil
     Fully
                               Don’t let hands off the chest wall
    recoil

                 Minimized
                interruption
                               Avoid fatique
                               Resume CPR
                               No pause for check pulse
WINTER


                       2005
                                       Circulation
ACLS     Template

Pulseless Arrest

                         Panita Worapratya
                   Emergency Department
              Prince of Songkhla University
Pulseless Arrest
•BLS algorithm, Call for help ,give CPR
•Give oxygen when avialable
•Attach moniter/ AED when avialable




 Check rhythm. Shockable ?
Pulseless Arrest
        •BLS algorithm, Call for help ,give CPR
        •Give oxygen when avialable
        •Attach moniter/ AED when avialable




         Check rhythm. Shockable ?


VF/VT                                                  Asystole/PEA



                                             Resume CPR immediately
                                             I.V/I.O access, given vasopressor
                                             • Epinephrine 1 mg I.V/ I.O q 3-5 min
                                             •Vasopressin 40 U I.V/I.O to replace
                                             epinerphine
                                             •Consider atropine 1 mg I.V/I.O for
                                             asystole or slow PEA
Pulseless Arrest
                        •BLS algorithm, Call for help ,give CPR
                        •Give oxygen when avialable
                        •Attach moniter/ AED when avialable




                         Check rhythm. Shockable ?


                VF/VT                                             Asystole/PEA


Give 1 shock
•Manual biphasic 200J
•Monophasic 300 J
•AED when avialable
Resume CPR immediately



   Check rhythm. Shockable ?
Check rhythm. Shockable ?


                VF/VT                                  Asystole/PEA



Give 1 shock
•Manual biphasic 200J
•Monophasic 300 J
•AED when avialable
Resume CPR immediately


    Check rhythm. Shockable ?


Continue CPR while defibrilator is charging
Give 1 shock
•Manual biphasic 200J
•Monophasic 300 J
•AED when avialable
Resume CPR immediately after shock
When I.V or I.O access give vasopress
Epinephrine 1 mg I.V/I.O q 3-5 min
Or one dose of vasopressin 40 U I.V/I.O
Continue CPR while defibrilator is charging
         Give 1 shock
         Resume CPR immediately after shock
         Epinephrine 1 mg I.V/I.O q 3-5 min




                  Check rhythm. Shockable ?



Continue CPR while defibrilator is charging
Give 1 shock
Resume CPR immediately after shock
Epinephrine 1 mg I.V/I.O q 3-5 min
Consider antiarrythmic drug
•Amiodarone 300 mg I.V/I.O then 150 mg I.V
•Lidocaine 1-1.5 mg/kg I.V/I.O then 0.5-7.5 mg/kg I.V/I.O
•Consider MgSO4 1-2 g I.V/I.O
•After 5 cycle of CPR , look for 6H,5T
Questions



• ชายอายุ 55 ปี เป็นโรคหัวใจอยู่เดิม ถูกนาส่งร.พ ด้วยเรื่องหมดสติ ญาติให้
  ประวัติว่าเป็นขณะออกกาลังกาย แรกรับ Unconsciousness, no
  pulse. EKG เป็นดังรูป ท่านจะให้การรักษาอย่างไร
          a.   Chest compression
          b.   Atropine 1 amp iv stat
          c.   Synchronized cardioversion 100 J
          d.   Defibrillation 200 J
          e.   Search for 6H, 5T
                              pulseless VF : Defibrillation 200 J
Questions



• หญิงอายุ 45 ปี Underlying เป็น CA breat with distance
  metastasis ญาติพบว่าตอนเช้าปลุกไม่ตื่น ตัวเย็น ซีดเขียว ไม่หายใจ
  ไม่ทราบว่าตั้งแต่เมื่อใด แรกรับ Unconsciousness, no pulse.
  EKG เป็นดังรูป ท่านจะให้การรักษาอย่างไร
         a.   Chest compression 5 cycle
         b.   Atropine 1 amp iv stat
         c.   Synchronized cardioversion 100 J
         d.   Defibrillation 200 J     Asystole : CPR 5 cycle
         e.   Search for 6H, 5T
Questions



• ขณะที่ทีมกาลัง CPR ผู้ป่วยหญิงอายุ 68 ปี ไม่ทราบประวัติ มาด้วยไม่
  รู้สึกตัว ได้ใส่ ET-Tube , i.v access, adrenaline 1 amp iv
  q 3-5 min และ High quality CPR แล้วไม่ดขึ้น EKG ยังคงเป็น
                                                  ี
  ดังรูป หลังจากท่านได้ทา Defibrillation ไปแล้ว 3 ครั้ง ท่านจะให้การ
  รักษาอย่างไรต่อ ? (อาจเลือกได้มากกว่า 1 ข้อ)
         a.   Antiarrhythmic drug       Refractory VT :
         b.   NaHCO3 50 mEq             •Amiodarone 300 mg i.v/i.o
         c.   Escalating dose epinephrine 3 mg
                                        •6H, 5T
         d.   Search for 6H, 5T
Contributing factor
    6H                        5T

•    Hypovolumia          •    Toxin
•    Hypoxia              •    Temponade (cardiac)
•    Hydrogen ion         •    Tension pneumothorax
•    Hypo/hyper kalemia   •    Thrombosis
•    Hypoglycemia         •    Trauma
•    Hypothermia
Questions
Route of drug administration


  • ผู้ป่วย cardiac arrest. EKG เป็น VF ซึ่งไม่ตอบสนองต่อการทา
    Defibrillation. พยาบาลได้พยายามเปิดเส้นเลือด 2 ครั้ง แต่ไม่เป็นผล
    ผู้ป่วยได้ใส่ ET-Tube แล้ว ท่านคิดว่าจะให้ยากู้ชีพทางใดดีที่สด
                                                                 ุ
           a.   Endotracheal
           b.   Femeral vein
           c.   Intraosseous
           d.   External jugular vein


                                           Intraosseous
Intraosseous
Site of administration

                         2 cm. above medial
                               condyle
                                                2 cm. above
                                              medial maleolous




   2 cm. below
 medial tuberosity
Questions



•   You are arrive on scene to fine CPR is in progress. Nursing staff
    report that the patient was recovering form pulmonary embolism
    and suddenly collapsed. There is no pulse or spontaneous
    respiration. High quallity CPR is in progress and effetive circulation
    is being provided with bag mask. An i.v is establish, you would
    now…?
           a. Give atropine 1 mg i.v
           b. Give NaHCO3 1 amp iv
           c. Immediate CPR
           d. Immediate endotracheal intubation
           e. Initiate transcutaneous pacing
Questions
• Following initiation of CPR and one shock for
Questions



• ผู้ป่วยชายอายุ 35 ปี เป็นช่างซ่อมเสาไฟฟ้า นาส่งร.พ เนื่องจากโดนไฟฟ้าแรงสูง
  ช๊อต และตกจากที่สูง 5 เมตร ไม่รู้สกตัว แรกรับไม่มีสัญญาณชีพ Moniter
                                    ึ
  EKG เป็นดังรูป จงให้การรักษา
           a.   Give atropine 1 mg i.v
           b.   Give epineprhine 1 mg i.v
           c.   Give Synchronized cardioversion 100 J
           d.   Immediate Defibrillation 200J
           e.   Initiate transcutaneous pacing
WINTER



                               2005
Brady &
      Template

Tacchycardia
                    Panita Worapratya
              Emergency Department
         Prince of Songkhla University
•   35 yr-old woman with palpitation, light headness and stable
    tacchycardia. EKG as picture. An IV has been established. What drug
    should be administered IV?
     o   Atropine 0.5 mg
     o   Lidocaine 1 mg/kg
     o   Epinephrine 2-10 µg/kg/min
     o   Adenosine 6 mg
WINTER
                             Template



67 Yr-old male ไม่รู้สึกตัวมา 30 min >V/S : BP 64/24,PR 30/min หลังจากท่านได้ใส่
 ท่อช่วยหายใจ เปิดเส้นเลือด ติด monitor EKG แล้ว คลื่นไฟฟ้าหัวใจเป็นดังรูปท่านคิดว่าการกระทาใด
 เหมาะสมที่สุด
   o    On external pacing
   o    Atropine 0.6 mg iv stat
   o    7.5 % NaHCO3 1 amp iv stat
   o    10% Ca-gluconate 1 amp iv stat
WINTER
                            Template



55 Yr-old female บ่นจุกแน่นหน้าอกที่ลิ้นปี่มา 1 ช.ม เป็นขณะพัก ประวัติว่าเคยไปตรวจที่คลินิค
 แพทย์บอกว่าหัวใจโต V/S : BP 140/86 PR 87/min ,regular-full peripheral
 pulse. EKG เป็นดังรูป ท่านจะทาอย่างไร
  o ให้ ASA, ISDN, Morphine
  o ให้ serial EKG ไปก่อน รอ cardiac enzyme
  o Consult cardiologist ทันที สงสัย AMI
WINTER
                       Template



58 Yr-old male บ่นแน่นหน้าอก หน้ามืดจะเป็นลม 30 นาที V/S BP 90/60 PR 33/min
 ,sweating, look anxiousness. EKG เป็นดังรูป ท่านจะทาอย่างไร
   o ให้ atropine 1 amp iv. stat
   o ให้ serial EKG รอ cardiac enzyme
   o Consult cardiologist ทันที สงสัย AMI
   o ใส่ Transcutaneous pacing
WINTER
                                 Template


61 Yr-old male หน้ามืด ขณะนั่งรับประทานอาหาร ไม่มจุกแน่นหน้าอก แต่มีใจสั่น V/S แรกรับ
                                                 ี
 BP 95/57 PR 42/min , irregular, sweating ถามตอบไม่รู้เรื่อง
  o ให้ atropine 1 amp iv. stat
  o ให้ serial EKG รอ cardiac enzyme
  o Consult cardiologist ทันที
  o ใส่ Transcutaneous pacing
WINTER
                                Template



66 Yr-old male, underlying CAD with history of coronary bypass
 graft. มาด้วยเป็นลมหมดสติ ไม่รู้สึกตัว BP วัดไม่ได้ ปลายมือปลายเท้าซีด เย็น
  o ให้ adenosine 6 mg iv stat
  o ให้ synchronized cardioversion 100 J
  o ให้ cordarone 150 mg iv stat
  o ให้ Defib 200 J
•   57 yr-old woman with palpitation, chest discomfort and tacchycardia.
    The moniter as picture. She becomes diaphoretic and BP 80/60
    mmHg. The next action is
     o   Obtain 12 lead EKG
     o   Perform immediate electrical cardioversion
     o   Establish IV and give sedation for electrical cardioversion
     o   Give amiodarone 300 mg IV push
• 27 ปีผู้ชาย อยู่ ๆ มีอาการใจสั่น หน้ามืด จะเป็นลม เหงื่อแตก ไม่เคยเป็นเช่นนี้มาก่อน
  มาที่ ER ปลายมือปลายเท้าเย็น BP 120/84 PR 210 EKG เป็นดังรูป จงให้การรักษา
     o   Adenosine 6 mg iv stat
     o   Give amiodarone 300 mg IV push
     o   Perform immediate Defibrillation
     o   Establish IV and give sedation for synchronized cardioversion
01
        WINTER
Basic   Template


EKG
                        Panita Worapratya
                  Emergency Department
             Prince of Songkhla University
Basic EKG   01
WINTER
Template
Basic EKG Analysis

•   Step 1
                 WINTER
             : Regular or not ?
                    Template
•   Step 2   : P wave ?
•   Step 3   : QRS ? (wide/narrow)
•   Step 4   : ST-segment elevation
•   Step 5   : QT segment
Step 1 : Regular or not ?
      WINTER
       Template
Rate & rhythm
                         WINTER
                            Template




• RR interval is 2 large block, rate = 150 beats/min (300/2)
• RR interval is 3 large block, rate = 100 beats/min (300/3)
• RR interval is 4 large block, rate = 75 beats/min (300/4)
Step 2 : P wave
                    WINTER
• Normal (sinus P wave) present?
                     Template


• Abnormal (non sinus P wave) present ?
Step 2 : P wave
                  WINTER
• No P wave : SVT or junctional
                   Template
Step 2 : P wave
                 WINTER
• Repalcement of P wave by other atrial wave?
                   Template
Step 3 : QRS complex
                 WINTER
                  Template
Stable
                 Wide QRS complex
V/S ?

    Unstable                          Stable




  Immediate
 Cardioversion        Consider common cause
                      •VT : Most common, especially
                      underlying heart disease
                      •SVT with pre-existing RBBB
                      •SVT with aberrant conduction
Differrentiate Wide QRS
                           WINTER
                               Wide QRS complex
                              Template
                                                             Excluded VT and
                                                                 WPW !!



             Typical RBB           Typical LBB                 IVCD
                                                                                RBB




                                                                                      LBB




                                                   •QRS wide > 0.11 s.
•QRS wide > 0.11 s         •QRS wide > 0.12 s
                                                   •Neither typical RBB nor
•rSR' or rsR' in V1        •Upright (monophasic)
                                                   LBB present
•Wide terminal S wave in   QRS in Lead I, V6       (เป็นตุด ไม่ใช่ LBB ก็ไม่ใช่ RBB ก็ไม่
                                                          ๊
Lead I, V6                 •Negative QRS in V1     เชิง)
Wide QRS differrentiation
                                                           Excluded VT and
                     Wide QRS complex                          WPW !!




                                     Modified Brugada Criteria for VT
                               Question                            Answer
                               1.    Is there AV dissociation?     Yes = VT
                               ( independent P/QRS, capture
                                     beats, fusion beat)
                               2. Is there an RS in any            No = VT
                               precordial lead?
                               3. Is there QRS onset to nadir of   Yes = VT
                               S wave > 100 msec in any
                               precordial lead?
WPW                            4. Are there morphologic criteria   Yest = VT
•Short PR                      for VT in both V1 or V6?
• Delta wave                   5. If no,                           SVT
• Wide QRS complex
Wide QRS differrentiation
                                                        Excluded VT and
                  Wide QRS complex                          WPW !!




                                  Modified Brugada Criteria for VT
                            Question                            Answer
                            1.    Is there AV dissociation?     Yes = VT
                            ( independent P/QRS, capture
                                  beats, fusion beat)
                            2. Is there an RS in any            No = VT
                            precordial lead?
AV dissociation             3. Is there QRS onset to nadir of   Yes = VT
                            S wave > 100 msec in any
                            precordial lead?
                            4. Are there morphologic criteria   Yest = VT
                            for VT in both V1 or V6?
                            5. If no,                           SVT
Wide QRS differrentiation
                                                                    Excluded VT and
                              Wide QRS complex                          WPW !!




                                              Modified Brugada Criteria for VT
                                        Question                            Answer
                                        1.    Is there AV dissociation?     Yes = VT
                                        ( independent P/QRS, capture
                                              beats, fusion beat)
                                        2. Is there an RS in any            No = VT
                                        precordial lead?
                                        3. Is there QRS onset to nadir of  Yes = VT
                                        S wave > 100 msec in any
                                                     100 % specific for VT
                                        precordial lead?
                                                       Sensitivity 26%
                                        4. Are there morphologic criteria   Yest = VT
                                        for VT in both V1 or V6?
No RS wave in any precordial leads      5. If no,                           SVT
Wide QRS differrentiation
                                              Excluded VT and
        Wide QRS complex                          WPW !!




                        Modified Brugada Criteria for VT
                  Question                            Answer
                  1.    Is there AV dissociation?     Yes = VT
                  ( independent P/QRS, capture
                        beats, fusion beat)
                  2. Is there an RS in any            No = VT
                  precordial lead?
                  3. Is there QRS onset to nadir of   Yes = VT
                  S wave > 160 msec in any
                  precordial lead?
                  4. Are there morphologic criteria   Yest = VT
                  for VT in both V1,2 or V6?
                  5. If no,                           SVT
Wide QRS differrentiation
                                              Excluded VT and
        Wide QRS complex                          WPW !!




                        Modified Brugada Criteria for VT
                  Question                            Answer
                  1.    Is there AV dissociation?     Yes = VT
                  ( independent P/QRS, capture
                        beats, fusion beat)
                  2. Is there an RS in any            No = VT
                  precordial lead?
                  3. Is there QRS onset to nadir of   Yes = VT
                  S wave > 100 msec in any
                  precordial lead?
                  4. Are there morphologic criteria   Yest = VT
                  for VT in both V1,2 or V6?
                  5. If no,                           SVT
Wide QRS differrentiation
                                              Excluded VT and
        Wide QRS complex                          WPW !!




                        Modified Brugada Criteria for VT
                  Question                            Answer
                  1.    Is there AV dissociation?     Yes = VT
                  ( independent P/QRS, capture
                        beats, fusion beat)
                  2. Is there an RS in any            No = VT
                  precordial lead?
                  3. Is there QRS onset to nadir of   Yes = VT
                  S wave > 100 msec in any
                  precordial lead?
                  4. Are there morphologic criteria   Yest = VT
                  for VT in both V1,2 or V6?
                  5. If no,                           SVT
Differrentiate Wide QRS
                           WINTER
                               Wide QRS complex
                              Template
                                                             Excluded VT and
                                                                 WPW !!



             Typical RBB           Typical LBB                 IVCD
                                                                                RBB




                                                                                      LBB




                                                   •QRS wide > 0.11 s.
•QRS wide > 0.11 s         •QRS wide > 0.12 s
                                                   •Neither typical RBB nor
•rSR' or rsR' in V1        •Upright (monophasic)
                                                   LBB present
•Wide terminal S wave in   QRS in Lead I, V6       (เป็นตุด ไม่ใช่ LBB ก็ไม่ใช่ RBB ก็ไม่
                                                          ๊
Lead I, V6                 •Negative QRS in V1     เชิง)
Step 4 : Analysis rhythm
Narrow complex
tacchycardia
                           WINTERWide QRS complex
                                 tacchycardia
                             Template
•   Sinus tacchycardia                •   Ventricular tacchycardia
•   Atrial fibrillation               •   SVT with aberrancy
•   Atrial flutter                    •   Pre-excited tacchycardia
•   AV nodal reentry
•   Accessory pathway-mediated
    tachycardia
•   Atrial tacchycardia (ectopic or
    reentrance)
•   Multifocal atrial tacchycardia
    (MAT)
•   Junctional tacchycardia
Step 4 : Analysis rhythm
Narrow complex tacchycardia

• Measure rate and rhythm
• Look for P wave & QRS relationship
   – If P > QRS : Atrial arrythmia
   – If P = QRS : Look for timing of P-wave
      • P in QRS             = AVRT
      • P fused with QRS     = AVNRT
   – If P < QRS : Junctional arrythmia
Step 4 : Analysis rhythm
Narrow complex tacchycardia

                     P > QRS
= Atrial arrythmia
Narrow complex tacchycardia
                                                                                P in QRS
                                        P = QRS                                 = AVRT




WPW : Normal electrical conduction through AV   AVRT with reentrance circuit consisting of 2 limbs,
node and accessory pathway cause slurred        the antrograde limb involve the normal QRS and
upstoke of QRS wave (delta wave                 retrograde limbs involve accessory pathway
Narrow complex tacchycardia
                                                                                   P fused with QRS
                                                P = QRS                                = AVNRT




AVNRT :Reentrance circuit around AV              These AV nodal reentry beats stimulate both the atrium and the
nodeleading to rapid stimulation of ventricle    ventricles rapidly in typically a 1 to 1 fashion with a strip of the EKG
and tacchycardia.                                shown at the bottom.
Narrow complex tacchycardia

                           P < QRS
= Junctional taccycardia
Wide complex tacchycardia




.   Monomorphic VT      Polymorphic VT
Narrow complex Bradycardia
Narrow complex Bradycardia
2nd degree AV
                                   Group of beat ?
                 block




            PR segment
   PR                       PR equal
Prolonger                    prolong


Morbitz I                   Morbitz II
WINTER



                               2005
Brady &
      Template

Tacchycardia
                    Panita Worapratya
              Emergency Department
         Prince of Songkhla University
Tacchycardia



                           •Assess & support ABCD
                           •Given oxygen
                           •Moniter EKG, BP, oxymetry
                           •Identify & treat reversible cause



                                 Is patient stable ?


             Yes                                                     Yes

•Establish AV access                                  Immediate Synchronized
•Obtain 12 Leads EKG                                  cardioversion
Is QRS narrow? (<0.12 s)                              Immediate I.V access
                                                      Expert consultation
                                                      If pulseless arrest develop, follow
                                                      guideline
Stable patient


                                       •Establish AV access
                                       •Obtain 12 Leads EKG
                                       Is QRS narrow? (<0.12 s)



                         Narrow QRS complex                      Wide QRS complex



                            Regular or not?



Regular-narrow complex                   Irregular –narrow complex
•Attempt vagal maneuver                  Possible AF, atrial flutter or MAT
•Adenosine 6 mg iv push                  Consider expert consultation
 then 12 mg iv push                      Controle rate : Diltiazem, B-blocker
may repeat 12 mg iv push at once         Caution B-blocker in CHF, Hypotension
Regular-narrow complex
                    •Attempt vagal maneuver
                    •Adenosine 6 mg iv push
                     then 12 mg iv push
                    may repeat 12 mg iv push at once



                         Does rhythm convert ?


Rhythm Convert                                    Rhythm Dose not Convert
= Possible SVT                                    = Possible atrial flutter, ectopic atrial
•Observe for recurrent                            tacchycardia, or junctional tacchycardia
•Treat recurrent with adenosine or AV             • Controle rate (diatiazem, b-blocker)
blocking agent (diltiazem/B-blocker)              • Treat underlying cause
                                                  • Expert consultation


      During evaluation consider
      =6H=                                   =5T=
      Hypovolumia                            Toxin
      Hypoxia                                Temponade
      Hydrogen ion                           Thrombosis
      Hypoglycemia                           Tension pneumothorax
      Hypo/hyper kalemia                     Trauma
      Hypothermia
Wide QRS complex



              Regular                                              Irregular




                                                If atrial fibrillation with aberrency
If ventricular tacchycardia or uncertain
                                                • Treat as irregular narrow complex
rhythm                                          tacchycardia
•Amiodarone 150 mg i.v over 10 min
                                                 If preexite atrial fibrillation (AF with
 Repeat as needed to maximum dose 2.2
                                                WPW)
g/24 hr
                                                • Expert consultation
•Prepare for synchronized cardioversion
                                                • Avoid AV nodal blocking agent
If SVT with aberrency ,
                                                (adenosine, digoxin, diltiazem,
•Give adenosine
                                                verapamil)
                                                • Consider antiarrhythmic drug
                                                (amiodarone 150 mg iv over 10 min)
                                                If recurrent polymorphic VT
                                                • Expert consultation
                                                If torsade de point give
                                                •MgSO4 1-2 g over 5-60 min then
                                                infusion
•   35 yr-old woman with palpitation, light headness and stable
    tacchycardia. EKG as picture. An IV has been established. What drug
    should be administered IV?
     o   Atropine 0.5 mg
     o   Lidocaine 1 mg/kg
     o   Epinephrine 2-10 µg/kg/min
     o   Adenosine 6 mg

                               Answer : SVT =Adenosine 6 mg
WINTER
                             Template



67 Yr-old male ไม่รู้สึกตัวมา 30 min >V/S : BP 64/24,PR 30/min หลังจากท่านได้ใส่
 ท่อช่วยหายใจ เปิดเส้นเลือด ติด monitor EKG แล้ว คลื่นไฟฟ้าหัวใจเป็นดังรูปท่านคิดว่าการกระทาใด
 เหมาะสมที่สุด
   o    On external pacing
   o    Atropine 0.6 mg iv stat
   o    7.5 % NaHCO3 1 amp iv stat
   o    10% Ca-gluconate 1 amp iv stat
WINTER
                            Template



55 Yr-old female บ่นจุกแน่นหน้าอกที่ลิ้นปี่มา 1 ช.ม เป็นขณะพัก ประวัติว่าเคยไปตรวจที่คลินิค
 แพทย์บอกว่าหัวใจโต V/S : BP 140/86 PR 87/min ,regular-full peripheral
 pulse. EKG เป็นดังรูป ท่านจะทาอย่างไร
  o ให้ ASA, ISDN, Morphine
  o ให้ serial EKG ไปก่อน รอ cardiac enzyme
  o Consult cardiologist ทันที สงสัย AMI
WINTER
                       Template



58 Yr-old male บ่นแน่นหน้าอก หน้ามืดจะเป็นลม 30 นาที V/S BP 90/60 PR 33/min
 ,sweating, look anxiousness. EKG เป็นดังรูป ท่านจะทาอย่างไร
   o ให้ atropine 1 amp iv. stat
   o ให้ serial EKG รอ cardiac enzyme
   o Consult cardiologist ทันที สงสัย AMI
   o ใส่ Transcutaneous pacing
WINTER
                                 Template


61 Yr-old male หน้ามืด ขณะนั่งรับประทานอาหาร ไม่มจุกแน่นหน้าอก แต่มีใจสั่น V/S แรกรับ
                                                 ี
 BP 95/57 PR 42/min , irregular, sweating ถามตอบไม่รู้เรื่อง
  o ให้ atropine 1 amp iv. stat
  o ให้ serial EKG รอ cardiac enzyme
  o Consult cardiologist ทันที
  o ใส่ Transcutaneous pacing
WINTER
                                Template



66 Yr-old male, underlying CAD with history of coronary bypass
 graft. มาด้วยเป็นลมหมดสติ ไม่รู้สึกตัว BP วัดไม่ได้ ปลายมือปลายเท้าซีด เย็น
  o ให้ adenosine 6 mg iv stat
  o ให้ synchronized cardioversion 100 J
  o ให้ cordarone 150 mg iv stat
  o ให้ Defib 200 J
•   57 yr-old woman with palpitation, chest discomfort and tacchycardia.
    The moniter as picture. She becomes diaphoretic and BP 80/60
    mmHg. The next action is
     o   Obtain 12 lead EKG
     o   Perform immediate electrical cardioversion
     o   Establish IV and give sedation for electrical cardioversion
     o   Give amiodarone 300 mg IV push

                Answer : VT with pulse
                            Immediate electrical cardioversion
• If the patient is monomorphic, unstable VT
  but has pulse, treat with synchronized
  cardioversion initial dose is 100J. and
  stepwise (200J, 300J, 360J)
• 27 ปีผู้ชาย อยู่ ๆ มีอาการใจสั่น หน้ามืด จะเป็นลม เหงื่อแตก ไม่เคยเป็นเช่นนี้มาก่อน
  มาที่ ER ปลายมือปลายเท้าเย็น BP 120/84 PR 210 EKG เป็นดังรูป จงให้การรักษา
     o   Adenosine 6 mg iv stat
     o   Give amiodarone 300 mg IV push
     o   Perform immediate Defibrillation
     o   Establish IV and give sedation for synchronized cardioversion
WINTER



                                  2005
Coronary
      Template

Syndrome
                       Panita Worapratya
                 Emergency Department
            Prince of Songkhla University
WINTER



                               2005
Basic EKG for
      Template

ACS
                    Panita Worapratya
              Emergency Department
         Prince of Songkhla University
EKG change during ischemia
        WINTER
         Template
EKG change during ischemia
        WINTER
         Template
EKG change during ischemia
        WINTER
         Template
         LCA origin : Lt. sinus of
              aortic valve
EKG change during ischemia
                WINTER
                  Template
                          LAD : Anteroseptal




   Distal LAD : Anastomosis
   with posterior diagonal
   branch of RCA
EKG change during ischemia
                  WINTER
                    Template




   LCx : Anterolateral wall
EKG change during ischemia
                          WINTER
                          Template
RCA : RV, inferior wall
Basic Leads group
                           WINTER
                                Template




       Wall                    EKG                Blood supply
Inferior wall   II, III, aVF         RCA or LCA
RV infarction   II, III, aVF, V4R    Prox. RCA
Basic Leads group
                        WINTER Template




     Wall               EKG                Blood supply
Inferior wall   II, III, aVF         RCA or LCA
RV infarction   II, III, aVF, V4R    Prox. RCA
Inf-Lat wall    II, III, aVF, V5-6   Dominant RCA or LCA
Basic Leads group
               WINTER
                   Template




     Wall          EKG         Blood supply
Anterior    V2-4         Mid LAD
Basic Leads group
                  WINTER
                     Template




     Wall            EKG           Blood supply
Anterior      V2-4          Mid LAD
Ant-Lat-Sep   V1-6, aVL     Prox LAD
Lateral       I, aVL,V5,6   Diagonal branch of LAD
Basic Leads group
                 WINTER
                     Template




    Wall             EKG        Blood supply
Anterior      V2-4         Mid LAD
Ant-Lat-Sep   V1-6, aVL    Prox LAD
Basic Leads group
                 WINTER
                     Template




    Wall             EKG        Blood supply
Anterior      V2-4         Mid LAD
Ant-Lat-Sep   V1-6, aVL    Prox LAD
Basic Leads group
                  WINTER
                     Template




    Wall             EKG          Blood supply
Anterior      V2-4          Mid LAD
Ant-Lat-Sep   V1-6, aVL     Prox LAD
Lateral       I, aVL,V5,6   Diagonal branch of LAD
Basic Leads group
                         WINTERTemplate



      Wall               EKG                   Blood supply
Inferior wall   II, III, aVF         RCA or LCA
RV infarction   II, III, aVF, V4R    Prox. RCA
Inf-Lat wall    II, III, aVF, V5-6   Dominant RCA or LCA
Anterior        V2-4                 Mid LAD
Ant-Lat-Sep     V1-6, aVL            Prox LAD
Lateral         I, aVL,V5,6          Diagonal branch of LAD
RCA or RCx
                        WINTER
                          Template




RCA occlusion                  RCx occlusion
•   ST elevation III > II      •   ST elevation II > III
•   ST depression in Lead I    •   ST elevate in Lead I
•   Isoelectric V4R            •   Negative V4R
Various cause of ST segment Deviation

ST elevation
                        WINTER ST depression
                            Template
                  Suggest
                    MI                  Symmetric ST
                                         inversion in
                                       contiguous leads




                                  Asymmetric ST
                   Early                                  “Scooping or strain
                                   depression in
               repolarization                                like pattern
                                    lateral leads
EKG Evolution in non-reperfused MI
           WINTER
             Template
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
             • Deep S wave in V1,V2
                                       MI   MI + RBBB   Brugada



             • Tall R in V5,V6
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis    Hyper K+

                       Template
                                         MI     MI + RBBB   Brugada



                            • Predominate negative QRS in V1
                            • QRS widening > 0.12 s
                            • Upright QRS in Lead I, V6
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
                                       MI   MI + RBBB   Brugada
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
                                       MI   MI + RBBB   Brugada
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
                                       MI   MI + RBBB   Brugada
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
                                       MI   MI + RBBB   Brugada
Morphology of ST elevate
LVH    LBB
                   WINTER
             Pericarditis   Hyper K+

                       Template
                                       MI   MI + RBBB   Brugada
Morphology of ST elevate
      WINTER
       Template
1                Chest comfort
                                          suggest of ischemia

2
     EMS careand Hosp. preparation
     • Moniter, ABC support, prepare for CPR & defibrillation
     • Administer MONA (morphine,oxygen,nitroglycerine, ASA) as needed
     • Obtain EKG, if ST-elevation
            • Notify receiving hospital
            • Begin fibrinolytic check list
     • Notify hospital to response MI.

    3
    Immediate ED assessment < 10 min                    Immediate ED general treatment
    • Check V/S, evaluate oxygen saturation             Start O2 4 L/min, maintain O2 sat > 90%
    • Obtain 12 leads EKG                               ASA 160-325 mg (if not given by EMS)
    • Brief target Hx & PE                              NTG sublingual,spray or i.v
    • Review fibrinolytic check list                    Morphine i.v if not improved by NTG
    • Obtain initial cardiac marker level, E-lyte and
    coagulopathy
    • Obtain portable CXR < 30min
4
                                         Review 12 Leads EKG


  5                                      9                                        13

                                              ST depression or dynamic T-
                                                                                   Normal or nondiagnostic ST-
    ST elevation or new LBBB                   wave, strongly suspected
                                                                                          wave change
   Strongly suspected STEMI                            ischemia
                                                                                   Intermediate or low risk
                                                  UA high risk /NSTEMI


  6                                          10                              14
 Start adjunctive treatment                  Start adjunctive treatment
         as indicated                                as indicated                  Develop High or Intermediate
• B-adrenergic receptor block            • Nitroglycerine                             risk criteria (Table 3,4)
• Clopidogrel                            • B-adrenergic blocker                                   or
• Heparin                                • Clopidogrel                                   Troponin positive
                                         • Glycoprotein Iib/IIIa            YES

                                                                                                        No
                                ≥ 12hr
  7                                          11                              15

                                                  Admit to moniter and             Consider admission to ED
      Time form onset of
                                                  risk assessment (Table              chest pain unit or
       symptoms ≤ 12 hr
                                                            3,4)                        monitered bed
                                                                                  • Serial cardiac marder
                                                                                  • Repeate EKG
                         < 12hr
                                                                                  • consider stress test
4
                                         Review 12 Leads EKG


  5                                      9                                  13

                                              ST depression or dynamic T-
                                                                             Normal or nondiagnostic ST-
    ST elevation or new LBBB                   wave, strongly suspected
                                                                                    wave change
   Strongly suspected STEMI                            ischemia
                                                                             Intermediate or low risk
                                                  UA high risk /NSTEMI


  6
 Start adjunctive treatment
         as indicated
• B-adrenergic receptor block
• Clopidogrel
• Heparin



                                ≥ 12hr
  7                                          11

                                                  Admit to moniter and
      Time form onset of
                                                  risk assessment (Table
       symptoms ≤ 12 hr
                                                            3,4)

                         < 12hr
7
         Time form onset of
          symptoms ≤ 12 hr




 8
Reperfusion therapy
•Reperfusion goal
     •Door to balloon (PCI) <
     90 min
     •Door to needle
     (fibrinolysis) 30min
•Continue adjuctive
therapy and..
     • ACE-I or ARB < 24 of
     onset
     • HMG co A reductase
     inhibitor
4
                            Review 12 Leads EKG


5                           9                                  13

                                 ST depression or dynamic T-
                                                                Normal or nondiagnostic ST-
 ST elevation or new LBBB         wave, strongly suspected
                                                                       wave change
Strongly suspected STEMI                  ischemia
                                                                Intermediate or low risk
                                     UA high risk /NSTEMI


                                10
                                Start adjunctive treatment
                                        as indicated
                            • Nitroglycerine
                            • B-adrenergic blocker
                            • Clopidogrel
                            • Glycoprotein Iib/IIIa


                                11

                                     Admit to moniter and
                                     risk assessment (Table
                                               3,4)
11

          Admit to moniter and
          risk assessment (Table
                    3,4)



12


High risk patient (table 3,4 for
risk stratification)
• Refractory ischemic chest pain
• Recurrent persistent STE
• Ventricular tacchycardia
• Hemodynamic instability
• Early invasive strategy, including
PCI and revascularization for shock
≤ 48 hr. of AMI
Continue ASA, heparin and other
therapy as indicated
• ACE-I/ ARB
• HMG co A reductase inhibitor
4
                            Review 12 Leads EKG


5                           9                                       13

                                ST depression or dynamic T-
                                                                     Normal or nondiagnostic ST-
 ST elevation or new LBBB        wave, strongly suspected
                                                                            wave change
Strongly suspected STEMI                 ischemia
                                                                     Intermediate or low risk
                                  UA high risk /NSTEMI


                                                               14
                                Start adjunctive treatment
                                        as indicated                 Develop High or Intermediate
                            • Nitroglycerine                            risk criteria (Table 3,4)
                            • B-adrenergic blocker                                  or
                            • Clopidogrel                                  Troponin positive
                            • Glycoprotein Iib/IIIa           YES

                                                                                          No
                                                               15

                                 Admit to moniter and                Consider admission to ED
                                 risk assessment (Table                 chest pain unit or
                                           3,4)                           monitered bed
                                                                    • Serial cardiac marder
                                                                    • Repeate EKG
                                                                    • consider stress test
15

     Consider admission to ED
        chest pain unit or
          monitered bed
     • Serial cardiac marder
     • Repeate EKG
     • consider stress test




     16
             Develop High or
            Intermediate risk
            criteria (Table 3,4)
                     or
            Troponin positive


      17

             If no evidence of
          ischemia or infarction,
          can discharge with F/U
Check list for STEMI fibrinolytic therapy

Step 1                Chest discomfort > 15 min, < 12 hr
                                                 YES


                       EKG show STEMI or new LBBB ?                         stop

                                                 YES

                   Are there contraindication for fibrinolysis ?
Step 2
  SBP > 180 mm Hg                                                   □ YES   □ NO
  DBP > 110 mmHg                                                    □ YES   □ NO
  ∆ Rt. VS Lt. arm SBP > 15 mmHg                                    □ YES   □ NO
  History of structural CNS disease                                 □ YES   □ NO
  Significant closed head or facial trauma < 3 mo           □ YES   □ NO
  Recent major surgery or trauma or GU/GI bleed < 6 wk              □ YES   □ NO
  Bleeding or clotting problem                                      □ YES   □ NO
  CPR > 10 min                                                      □ YES   □ NO
  Pregnant female                                                   □ YES   □ NO
  Serious systemic disease                                  □ YES   □ NO
Check list for STEMI fibrinolytic therapy



                    Are there contraindication for fibrinolysis ?
Step 2
                                                   NO



Step 3                        Is a pateint any high risk ?
                   If any of following check “YES” , consider PCI



  HR ≥ 100/min and SBP < 100 mmHg                            □ YES   □ NO
  Pulmonary edmema (rale)                                            □ YES   □ NO
  Sign of shock (cool, clamy)                                        □ YES   □ NO
  Contraindication for fibrinolytid therapy                          □ YES   □ NO
Table 3 : Likely hood of ischemic etiology (short term risk)
Part I : Chest pain patient without ST segment change
         Likelihood of ischemic etiology

                      A : High likelihood            B : Intermediate likelihood   C : Low likelihood
                      Any of following               No A with any of following    No A & B with any of following


History               • Chief complaint of Lt. arm
                      pain or discomfort plus
                      Current pain reproduce pain
                      of prior pain document
                      angina and Known CAD
                      including MI

Physical Exam         • Transient MR
                      • Hypotension
                      • Diaphoresis
                      • Pulmonary edema or rale

EKG                   • New (or persume new)
                      transient ST deviation (>0.5
                      mm) or T wave inversion (> 2
                      mm) with symptoms

Cardiac marker        • Elevate troponin I or T
                      • Elevate CK-MB
Table 3 : Likely hood of ischemic etiology (short term risk)
Part I : Chest pain patient without ST segment change
         Likelihood of ischemic etiology

                      A : High likelihood            B : Intermediate likelihood         C : Low likelihood
                      Any of following               No A with any of following          No A & B with any of following


History               • Chief complaint of Lt. arm   • Chief complaint is Lt. arm pain
                      pain or discomfort plus        or dyscomfort
                      Current pain reproduce pain    • Age > 70 yr.
                      of prior pain document         • Male sex
                      angina and Known CAD           • Diabetic mellitus
                      including MI

Physical Exam         • Transient MR                 • Extravascular disease
                      • Hypotension
                      • Diaphoresis
                      • Pulmonary edema or rale

EKG                   • New (or persume new)         • Fixd Q wave
                      transient ST deviation (>0.5   • Abnormal ST segment or T
                      mm) or T wave inversion (> 2   wave that are not new
                      mm) with symptoms

Cardiac marker        • Elevate troponin I or T      • Normal
                      • Elevate CK-MB
Table 3 : Likely hood of ischemic etiology (short term risk)
Part I : Chest pain patient without ST segment change
         Likelihood of ischemic etiology

                      A : High likelihood            B : Intermediate likelihood         C : Low likelihood
                      Any of following               No A with any of following          No A & B with any of following


History               • Chief complaint of Lt. arm   • Chief complaint is Lt. arm pain   • Probable ischemic symptoms
                      pain or discomfort plus        or dyscomfort                       • Recent cocaine use
                      Current pain reproduce pain    • Age > 70 yr.
                      of prior pain document         • Male sex
                      angina and Known CAD           • Diabetic mellitus
                      including MI

Physical Exam         • Transient MR                 • Extravascular disease             • Chest discomfort reproduce
                      • Hypotension                                                      by palpation
                      • Diaphoresis
                      • Pulmonary edema or rale

EKG                   • New (or persume new)         • Fixd Q wave                       • Normal EKG or T wave
                      transient ST deviation (>0.5   • Abnormal ST segment or T          flattening or T wave inversion
                      mm) or T wave inversion (> 2   wave that are not new               in leads which dominant R
                      mm) with symptoms                                                  wave

Cardiac marker        • Elevate troponin I or T      • Normal                            • Normal
                      • Elevate CK-MB
Table 3 : Likely hood of ischemic etiology (short term risk)
Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high
or intermediate likelihood of ischemia (column A, B in Part I)
                    High risk                          Intermediate risk      Low risk
                    Any of the following               Any of the following   Any of the following

History             • Accelerating tempo of ischemic
                    symptoms over prior 48 hr.




Character of pain   • Prolong continue > 20 min of
                    rest pain


Physical exam       • Age > 75 yr
                    • Pulmonary edema secondary to
                    ischemia
                    • New or worse MR
                    • Hypotension,
                    brady/tacchycardia
                    • S3 gallops or new or worsening
                    rale
EKG                 • Transient ST segment deviation
                    (≥ 0.5 mm with rest agina)
                    • Persume new LBBB
                    • Sustain VT

Cardiac marker      • Elevate cardiac troponin
                    • Elevate CK-MB
Table 3 : Likely hood of ischemic etiology (short term risk)
Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high
or intermediate likelihood of ischemia (column A, B in Part I)
                    High risk                             Intermediate risk                       Low risk
                    Any of the following                  Any of the following                    Any of the following

History             • Accelerating tempo of ischemic      • Prior MI or
                    symptoms over prior 48 hr.            • Peripheral artery disease or
                                                          • Cerebrovascular disease or
                                                          • CABG, prior ASA use

Character of pain   • Prolong continue > 20 min of rest   • Prolong > 20 min rest angina is now
                    pain                                  resolved (moderate to high likely
                                                          hood of CAD)
                                                          • Rest angina (<20 min) or relieved
                                                          by rest or sublingual nitroglycerine


Physical exam       • Age > 75 yr                         • Age > 70 yr
                    • Pulmonary edema secondary to
                    ischemia
                    • New or worse MR
                    • Hypotension, brady/tacchycardia
                    • S3 gallops or new or worsening
                    rale


EKG                 • Transient ST segment deviation (≥   • T wave inversion ≥ 2 mm.
                    0.5 mm with rest agina)               • Pathologic T wave or Q wave that
                    • Persume new LBBB                    are not new
                    • Sustain VT

Cardiac marker      • Elevate cardiac troponin            • Any or above , plus normal
                    • Elevate CK-MB
Table 3 : Likely hood of ischemic etiology (short term risk)
Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high
or intermediate likelihood of ischemia (column A, B in Part I)
                    High risk                             Intermediate risk                       Low risk
                    Any of the following                  Any of the following                    Any of the following

History             • Accelerating tempo of ischemic      • Prior MI or
                    symptoms over prior 48 hr.            • Peripheral artery disease or
                                                          • Cerebrovascular disease or
                                                          • CABG, prior ASA use

Character of pain   • Prolong continue > 20 min of rest   • Prolong > 20 min rest angina is now   • New onset functional angina (Class
                    pain                                  resolved (moderate to high likely       III or IV) in past 2 wk. without
                                                          hood of CAD)                            prolong rest pain (but with
                                                          • Rest angina (<20 min) or relieved     moderate to high likelihood of CAD)
                                                          by rest or sublingual nitroglycerine


Physical exam       • Age > 75 yr                         • Age > 70 yr
                    • Pulmonary edema secondary to
                    ischemia
                    • New or worse MR
                    • Hypotension, brady/tacchycardia
                    • S3 gallops or new or worsening
                    rale


EKG                 • Transient ST segment deviation (≥   • T wave inversion ≥ 2 mm.              • Normal or unchanged EKG during
                    0.5 mm with rest agina)               • Pathologic T wave or Q wave that      an episode of chest discomfort
                    • Persume new LBBB                    are not new
                    • Sustain VT

Cardiac marker      • Elevate cardiac troponin            • Any or above , plus normal            • Normal
                    • Elevate CK-MB
Table 4 : TIMI risk score for patient with UA and NSTEMI

                                         Risk factor of CAD
                                         • Family Hx of CAD
           Predictor variable            • HT
                                         • Hypercholesteralemia
                                         • D.M
Age > 65 year                            • Current smoker
≥ 3 risk factor of CAD
ASA used in Last 7 days
                                          ≥ 2 angina event in last 24 hr
Recent , severe symptoms of angina
Elevated cardiac marker
ST deviation ≥ 0.5 mm.
Prior coronary a. stenosis > 50%         •ST depression > 0.5 mm is
                                         significant
                                         •Transient ST deviation > 0.5
                                         mm < 20 min is high risk
                                         •STE > 1 mm (>20 min) =
                                         STEMI
Table 4 : TIMI risk score for patient with UA and NSTEMI

Calculated        Risk of ≥ 1        Risk status
TIMI risk        primary end
score             point in 14
                     days
0-2                  5-8%                Low
3-4                 13-20%           Intermediate
5                    26%                High
6 or 7               41%                High


                Predictor variable
Age > 65 year
≥ 3 risk factor of CAD
ASA used in Last 7 days
Recent , severe symptoms of angina
Elevated cardiac marker
ST deviation ≥ 0.5 mm.
Prior coronary a. stenosis > 50%
Case Presentation
                               WINTER
• ชายอายุ 42 ปี : 3 วันมีอาการใจสั่น แน่นหน้าอก ไม่สัมพันธ์กับการออกกาลัง
                            Template ก่อนมาร.พ เพื่อนนาส่งร.พ
  อาการเป็น ๆ หาย ๆ เจ็บหน้าอกครั้งสุดท้าย 45 นาที
 V/S : BT 36 c PR 40/min , RR 20/min, BP 69/37 mmHg
 Consciousness     พูดเป็นคา ทาตามสั่งบ้าง ไม่ทาตามสั่งบ้าง เหงื่อแตก มือเท้าเย็น
   บ่นแน่นหน้าอก
Case Presentation
A : Anxiousness.
                WINTER
                     Template
B : Lung is clear . O2 sat วัดไม่ได้
C : PR 40/min,irregular rate, no murmur. Poor
peripheral pluse, acrocyanosis.
D : E3V5M5-6 No moter weakness.
Case Presentation
  WINTER
   Template
Case Presentation
  WINTER
   Template
Case Presentation
  WINTER
   Template
Case Presentation
Initial management
                       WINTER
                         Template
    A : None
    B : O2 cannular 3 LPM
    C : Moniter EKG, I.V access
         ส่ง Lab + cardiac enzyme
         0.9 % NSS iv load 1000 ml iv freee flow 300 ml Atropine 1
    amp iv stat
         On External pacemaker
Case Presentation
                    WINTER
                       Template
หลัง Load fluid ครบ 300 ml และให้ atropine 1 amp
V/S : PR 65/min BP 72/47 , O2 sat 100%
เริ่มถามตอบไม่รู้เรื่อง มองไม่สื่อความหมาย
Mx : ET-Tube No 7.5 ขีด 23 cm.
EKG เป็นดังรูป (next slide)
Case Presentation
                       WINTER
หลัง Load fluid ครบ 300 ml และให้ atropine 1 amp
                         Template
V/S : PR 65/min BP 72/47 , O2 sat 100%
เริ่มถามตอบไม่รู้เรื่อง มองไม่สื่อความหมาย
Mx : ET-Tube No 7.5 ขีด 23 cm.
Case Presentation
  WINTER
   Template
Case Presentation

  ท่านจะทาอย่างไรต่อไป
                        WINTER
• At 19.37 หลังใส่ ET-Tube คนไข้เริ่ม unconsciousness , คลา pulse ไม่ได้
                         Template
Case Presentation
                        WINTER
• หลังจาก CPRไปได้ 2 นาที ให้ adrenaline run q 3 min คลื่นไฟฟ้า
                               Template
  หัวใจเป็นดังรูป ท่านจะทาอย่างไรต่อไป
Case Presentation
                           WINTER
• ได้ทา defibrillation x 3 ครั้ง EKG ยังคงเป็นเช่นนี้ ท่านจะทาอย่างไรต่อไป
                              Template
Case Presentation

  ท่านจะทาอย่างไรต่อไป
                         WINTER
• หลังจากท่าน ได้ check lead, ขยาย amplitude แล้ว EKG เป็นดังนี้
                           Template
Case Presentation
                                WINTER
                                   Template



หลังจากท่านได้ Defibrillation แล้ว EKG เป็นดังนี้ ท่านจะทาอย่างไร
     o Atropine 1 amp iv stat
     o External pacemaker
     o Transfer to ICU
     o Load 0.9% NSS
WINTER



                              2005
Thank You
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                   Panita Worapratya
             Emergency Department
        Prince of Songkhla University
Common cause of ST depression
03




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                                         Review 12 Leads EKG


  5                                      9                                        13

                                              ST depression or dynamic T-
                                                                                   Normal or nondiagnostic ST-
    ST elevation or new LBBB                   wave, strongly suspected
                                                                                          wave change
   Strongly suspected STEMI                            ischemia
                                                                                   Intermediate or low risk
                                                  UA high risk /NSTEMI


  6                                          10                              14
 Start adjunctive treatment                  Start adjunctive treatment
         as indicated                                as indicated                  Develop High or Intermediate
• B-adrenergic receptor block            • Nitroglycerine                             risk criteria (Table 3,4)
• Clopidogrel                            • B-adrenergic blocker                                   or
• Heparin                                • Clopidogrel                                   Troponin positive
                                         • Glycoprotein Iib/IIIa            YES

                                                                                                        No
                                ≥ 12hr
  7                                          11                              15

                                                  Admit to moniter and             Consider admission to ED
      Time form onset of
                                                  risk assessment (Table              chest pain unit or
       symptoms ≤ 12 hr
                                                            3,4)                        monitered bed
                                                                                  • Serial cardiac marder
                                                                                  • Repeate EKG
                         < 12hr
                                                                                  • consider stress test

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แนวทางการดูแลรักษาลิ้มเลือดอุดตันในปอด ในผูปวยฉุกเฉิน
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Based on the information provided:- The patient has palpitations, chest discomfort and tachycardia- The monitor shows wide-complex tachycardia (likely ventricular tachycardia)- The patient's condition is deteriorating with diaphoresis and dropping blood pressureThe immediate next step in this emergency situation should be to perform immediate electrical cardioversion to terminate the potentially life-threatening arrhythmia. Obtaining a 12-lead EKG can be done concurrently but should not delay cardioversion.The appropriate response is: "Perform immediate electrical cardioversion

  • 1. 01 WINTER 2005 Circulation ACLS Template Panita Worapratya Emergency Department Prince of Songkhla University
  • 2. Effective Chest compression Goals How to achieve Push 100/min Push hard & Deep 1/3 of chest wall fast Fully recoil Fully Don’t let hands off the chest wall recoil Minimized interruption Avoid fatique Resume CPR No pause for check pulse
  • 3. WINTER 2005 Circulation ACLS Template Pulseless Arrest Panita Worapratya Emergency Department Prince of Songkhla University
  • 4. Pulseless Arrest •BLS algorithm, Call for help ,give CPR •Give oxygen when avialable •Attach moniter/ AED when avialable Check rhythm. Shockable ?
  • 5. Pulseless Arrest •BLS algorithm, Call for help ,give CPR •Give oxygen when avialable •Attach moniter/ AED when avialable Check rhythm. Shockable ? VF/VT Asystole/PEA Resume CPR immediately I.V/I.O access, given vasopressor • Epinephrine 1 mg I.V/ I.O q 3-5 min •Vasopressin 40 U I.V/I.O to replace epinerphine •Consider atropine 1 mg I.V/I.O for asystole or slow PEA
  • 6. Pulseless Arrest •BLS algorithm, Call for help ,give CPR •Give oxygen when avialable •Attach moniter/ AED when avialable Check rhythm. Shockable ? VF/VT Asystole/PEA Give 1 shock •Manual biphasic 200J •Monophasic 300 J •AED when avialable Resume CPR immediately Check rhythm. Shockable ?
  • 7. Check rhythm. Shockable ? VF/VT Asystole/PEA Give 1 shock •Manual biphasic 200J •Monophasic 300 J •AED when avialable Resume CPR immediately Check rhythm. Shockable ? Continue CPR while defibrilator is charging Give 1 shock •Manual biphasic 200J •Monophasic 300 J •AED when avialable Resume CPR immediately after shock When I.V or I.O access give vasopress Epinephrine 1 mg I.V/I.O q 3-5 min Or one dose of vasopressin 40 U I.V/I.O
  • 8. Continue CPR while defibrilator is charging Give 1 shock Resume CPR immediately after shock Epinephrine 1 mg I.V/I.O q 3-5 min Check rhythm. Shockable ? Continue CPR while defibrilator is charging Give 1 shock Resume CPR immediately after shock Epinephrine 1 mg I.V/I.O q 3-5 min Consider antiarrythmic drug •Amiodarone 300 mg I.V/I.O then 150 mg I.V •Lidocaine 1-1.5 mg/kg I.V/I.O then 0.5-7.5 mg/kg I.V/I.O •Consider MgSO4 1-2 g I.V/I.O •After 5 cycle of CPR , look for 6H,5T
  • 9. Questions • ชายอายุ 55 ปี เป็นโรคหัวใจอยู่เดิม ถูกนาส่งร.พ ด้วยเรื่องหมดสติ ญาติให้ ประวัติว่าเป็นขณะออกกาลังกาย แรกรับ Unconsciousness, no pulse. EKG เป็นดังรูป ท่านจะให้การรักษาอย่างไร a. Chest compression b. Atropine 1 amp iv stat c. Synchronized cardioversion 100 J d. Defibrillation 200 J e. Search for 6H, 5T pulseless VF : Defibrillation 200 J
  • 10. Questions • หญิงอายุ 45 ปี Underlying เป็น CA breat with distance metastasis ญาติพบว่าตอนเช้าปลุกไม่ตื่น ตัวเย็น ซีดเขียว ไม่หายใจ ไม่ทราบว่าตั้งแต่เมื่อใด แรกรับ Unconsciousness, no pulse. EKG เป็นดังรูป ท่านจะให้การรักษาอย่างไร a. Chest compression 5 cycle b. Atropine 1 amp iv stat c. Synchronized cardioversion 100 J d. Defibrillation 200 J Asystole : CPR 5 cycle e. Search for 6H, 5T
  • 11. Questions • ขณะที่ทีมกาลัง CPR ผู้ป่วยหญิงอายุ 68 ปี ไม่ทราบประวัติ มาด้วยไม่ รู้สึกตัว ได้ใส่ ET-Tube , i.v access, adrenaline 1 amp iv q 3-5 min และ High quality CPR แล้วไม่ดขึ้น EKG ยังคงเป็น ี ดังรูป หลังจากท่านได้ทา Defibrillation ไปแล้ว 3 ครั้ง ท่านจะให้การ รักษาอย่างไรต่อ ? (อาจเลือกได้มากกว่า 1 ข้อ) a. Antiarrhythmic drug Refractory VT : b. NaHCO3 50 mEq •Amiodarone 300 mg i.v/i.o c. Escalating dose epinephrine 3 mg •6H, 5T d. Search for 6H, 5T
  • 12.
  • 13. Contributing factor 6H 5T • Hypovolumia • Toxin • Hypoxia • Temponade (cardiac) • Hydrogen ion • Tension pneumothorax • Hypo/hyper kalemia • Thrombosis • Hypoglycemia • Trauma • Hypothermia
  • 14. Questions Route of drug administration • ผู้ป่วย cardiac arrest. EKG เป็น VF ซึ่งไม่ตอบสนองต่อการทา Defibrillation. พยาบาลได้พยายามเปิดเส้นเลือด 2 ครั้ง แต่ไม่เป็นผล ผู้ป่วยได้ใส่ ET-Tube แล้ว ท่านคิดว่าจะให้ยากู้ชีพทางใดดีที่สด ุ a. Endotracheal b. Femeral vein c. Intraosseous d. External jugular vein Intraosseous
  • 15.
  • 16. Intraosseous Site of administration 2 cm. above medial condyle 2 cm. above medial maleolous 2 cm. below medial tuberosity
  • 17. Questions • You are arrive on scene to fine CPR is in progress. Nursing staff report that the patient was recovering form pulmonary embolism and suddenly collapsed. There is no pulse or spontaneous respiration. High quallity CPR is in progress and effetive circulation is being provided with bag mask. An i.v is establish, you would now…? a. Give atropine 1 mg i.v b. Give NaHCO3 1 amp iv c. Immediate CPR d. Immediate endotracheal intubation e. Initiate transcutaneous pacing
  • 18. Questions • Following initiation of CPR and one shock for
  • 19. Questions • ผู้ป่วยชายอายุ 35 ปี เป็นช่างซ่อมเสาไฟฟ้า นาส่งร.พ เนื่องจากโดนไฟฟ้าแรงสูง ช๊อต และตกจากที่สูง 5 เมตร ไม่รู้สกตัว แรกรับไม่มีสัญญาณชีพ Moniter ึ EKG เป็นดังรูป จงให้การรักษา a. Give atropine 1 mg i.v b. Give epineprhine 1 mg i.v c. Give Synchronized cardioversion 100 J d. Immediate Defibrillation 200J e. Initiate transcutaneous pacing
  • 20. WINTER 2005 Brady & Template Tacchycardia Panita Worapratya Emergency Department Prince of Songkhla University
  • 21. 35 yr-old woman with palpitation, light headness and stable tacchycardia. EKG as picture. An IV has been established. What drug should be administered IV? o Atropine 0.5 mg o Lidocaine 1 mg/kg o Epinephrine 2-10 µg/kg/min o Adenosine 6 mg
  • 22. WINTER Template 67 Yr-old male ไม่รู้สึกตัวมา 30 min >V/S : BP 64/24,PR 30/min หลังจากท่านได้ใส่ ท่อช่วยหายใจ เปิดเส้นเลือด ติด monitor EKG แล้ว คลื่นไฟฟ้าหัวใจเป็นดังรูปท่านคิดว่าการกระทาใด เหมาะสมที่สุด o On external pacing o Atropine 0.6 mg iv stat o 7.5 % NaHCO3 1 amp iv stat o 10% Ca-gluconate 1 amp iv stat
  • 23. WINTER Template 55 Yr-old female บ่นจุกแน่นหน้าอกที่ลิ้นปี่มา 1 ช.ม เป็นขณะพัก ประวัติว่าเคยไปตรวจที่คลินิค แพทย์บอกว่าหัวใจโต V/S : BP 140/86 PR 87/min ,regular-full peripheral pulse. EKG เป็นดังรูป ท่านจะทาอย่างไร o ให้ ASA, ISDN, Morphine o ให้ serial EKG ไปก่อน รอ cardiac enzyme o Consult cardiologist ทันที สงสัย AMI
  • 24. WINTER Template 58 Yr-old male บ่นแน่นหน้าอก หน้ามืดจะเป็นลม 30 นาที V/S BP 90/60 PR 33/min ,sweating, look anxiousness. EKG เป็นดังรูป ท่านจะทาอย่างไร o ให้ atropine 1 amp iv. stat o ให้ serial EKG รอ cardiac enzyme o Consult cardiologist ทันที สงสัย AMI o ใส่ Transcutaneous pacing
  • 25. WINTER Template 61 Yr-old male หน้ามืด ขณะนั่งรับประทานอาหาร ไม่มจุกแน่นหน้าอก แต่มีใจสั่น V/S แรกรับ ี BP 95/57 PR 42/min , irregular, sweating ถามตอบไม่รู้เรื่อง o ให้ atropine 1 amp iv. stat o ให้ serial EKG รอ cardiac enzyme o Consult cardiologist ทันที o ใส่ Transcutaneous pacing
  • 26. WINTER Template 66 Yr-old male, underlying CAD with history of coronary bypass graft. มาด้วยเป็นลมหมดสติ ไม่รู้สึกตัว BP วัดไม่ได้ ปลายมือปลายเท้าซีด เย็น o ให้ adenosine 6 mg iv stat o ให้ synchronized cardioversion 100 J o ให้ cordarone 150 mg iv stat o ให้ Defib 200 J
  • 27. 57 yr-old woman with palpitation, chest discomfort and tacchycardia. The moniter as picture. She becomes diaphoretic and BP 80/60 mmHg. The next action is o Obtain 12 lead EKG o Perform immediate electrical cardioversion o Establish IV and give sedation for electrical cardioversion o Give amiodarone 300 mg IV push
  • 28. • 27 ปีผู้ชาย อยู่ ๆ มีอาการใจสั่น หน้ามืด จะเป็นลม เหงื่อแตก ไม่เคยเป็นเช่นนี้มาก่อน มาที่ ER ปลายมือปลายเท้าเย็น BP 120/84 PR 210 EKG เป็นดังรูป จงให้การรักษา o Adenosine 6 mg iv stat o Give amiodarone 300 mg IV push o Perform immediate Defibrillation o Establish IV and give sedation for synchronized cardioversion
  • 29. 01 WINTER Basic Template EKG Panita Worapratya Emergency Department Prince of Songkhla University
  • 30. Basic EKG 01 WINTER Template
  • 31. Basic EKG Analysis • Step 1 WINTER : Regular or not ? Template • Step 2 : P wave ? • Step 3 : QRS ? (wide/narrow) • Step 4 : ST-segment elevation • Step 5 : QT segment
  • 32. Step 1 : Regular or not ? WINTER Template
  • 33. Rate & rhythm WINTER Template • RR interval is 2 large block, rate = 150 beats/min (300/2) • RR interval is 3 large block, rate = 100 beats/min (300/3) • RR interval is 4 large block, rate = 75 beats/min (300/4)
  • 34. Step 2 : P wave WINTER • Normal (sinus P wave) present? Template • Abnormal (non sinus P wave) present ?
  • 35. Step 2 : P wave WINTER • No P wave : SVT or junctional Template
  • 36. Step 2 : P wave WINTER • Repalcement of P wave by other atrial wave? Template
  • 37. Step 3 : QRS complex WINTER Template Stable Wide QRS complex V/S ? Unstable Stable Immediate Cardioversion Consider common cause •VT : Most common, especially underlying heart disease •SVT with pre-existing RBBB •SVT with aberrant conduction
  • 38. Differrentiate Wide QRS WINTER Wide QRS complex Template Excluded VT and WPW !! Typical RBB Typical LBB IVCD RBB LBB •QRS wide > 0.11 s. •QRS wide > 0.11 s •QRS wide > 0.12 s •Neither typical RBB nor •rSR' or rsR' in V1 •Upright (monophasic) LBB present •Wide terminal S wave in QRS in Lead I, V6 (เป็นตุด ไม่ใช่ LBB ก็ไม่ใช่ RBB ก็ไม่ ๊ Lead I, V6 •Negative QRS in V1 เชิง)
  • 39. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? 3. Is there QRS onset to nadir of Yes = VT S wave > 100 msec in any precordial lead? WPW 4. Are there morphologic criteria Yest = VT •Short PR for VT in both V1 or V6? • Delta wave 5. If no, SVT • Wide QRS complex
  • 40. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? AV dissociation 3. Is there QRS onset to nadir of Yes = VT S wave > 100 msec in any precordial lead? 4. Are there morphologic criteria Yest = VT for VT in both V1 or V6? 5. If no, SVT
  • 41. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? 3. Is there QRS onset to nadir of Yes = VT S wave > 100 msec in any 100 % specific for VT precordial lead? Sensitivity 26% 4. Are there morphologic criteria Yest = VT for VT in both V1 or V6? No RS wave in any precordial leads 5. If no, SVT
  • 42. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? 3. Is there QRS onset to nadir of Yes = VT S wave > 160 msec in any precordial lead? 4. Are there morphologic criteria Yest = VT for VT in both V1,2 or V6? 5. If no, SVT
  • 43. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? 3. Is there QRS onset to nadir of Yes = VT S wave > 100 msec in any precordial lead? 4. Are there morphologic criteria Yest = VT for VT in both V1,2 or V6? 5. If no, SVT
  • 44. Wide QRS differrentiation Excluded VT and Wide QRS complex WPW !! Modified Brugada Criteria for VT Question Answer 1. Is there AV dissociation? Yes = VT ( independent P/QRS, capture beats, fusion beat) 2. Is there an RS in any No = VT precordial lead? 3. Is there QRS onset to nadir of Yes = VT S wave > 100 msec in any precordial lead? 4. Are there morphologic criteria Yest = VT for VT in both V1,2 or V6? 5. If no, SVT
  • 45.
  • 46. Differrentiate Wide QRS WINTER Wide QRS complex Template Excluded VT and WPW !! Typical RBB Typical LBB IVCD RBB LBB •QRS wide > 0.11 s. •QRS wide > 0.11 s •QRS wide > 0.12 s •Neither typical RBB nor •rSR' or rsR' in V1 •Upright (monophasic) LBB present •Wide terminal S wave in QRS in Lead I, V6 (เป็นตุด ไม่ใช่ LBB ก็ไม่ใช่ RBB ก็ไม่ ๊ Lead I, V6 •Negative QRS in V1 เชิง)
  • 47. Step 4 : Analysis rhythm Narrow complex tacchycardia WINTERWide QRS complex tacchycardia Template • Sinus tacchycardia • Ventricular tacchycardia • Atrial fibrillation • SVT with aberrancy • Atrial flutter • Pre-excited tacchycardia • AV nodal reentry • Accessory pathway-mediated tachycardia • Atrial tacchycardia (ectopic or reentrance) • Multifocal atrial tacchycardia (MAT) • Junctional tacchycardia
  • 48. Step 4 : Analysis rhythm Narrow complex tacchycardia • Measure rate and rhythm • Look for P wave & QRS relationship – If P > QRS : Atrial arrythmia – If P = QRS : Look for timing of P-wave • P in QRS = AVRT • P fused with QRS = AVNRT – If P < QRS : Junctional arrythmia
  • 49. Step 4 : Analysis rhythm Narrow complex tacchycardia P > QRS = Atrial arrythmia
  • 50. Narrow complex tacchycardia P in QRS P = QRS = AVRT WPW : Normal electrical conduction through AV AVRT with reentrance circuit consisting of 2 limbs, node and accessory pathway cause slurred the antrograde limb involve the normal QRS and upstoke of QRS wave (delta wave retrograde limbs involve accessory pathway
  • 51. Narrow complex tacchycardia P fused with QRS P = QRS = AVNRT AVNRT :Reentrance circuit around AV These AV nodal reentry beats stimulate both the atrium and the nodeleading to rapid stimulation of ventricle ventricles rapidly in typically a 1 to 1 fashion with a strip of the EKG and tacchycardia. shown at the bottom.
  • 52. Narrow complex tacchycardia P < QRS = Junctional taccycardia
  • 53. Wide complex tacchycardia . Monomorphic VT Polymorphic VT
  • 56. 2nd degree AV Group of beat ? block PR segment PR PR equal Prolonger prolong Morbitz I Morbitz II
  • 57.
  • 58. WINTER 2005 Brady & Template Tacchycardia Panita Worapratya Emergency Department Prince of Songkhla University
  • 59. Tacchycardia •Assess & support ABCD •Given oxygen •Moniter EKG, BP, oxymetry •Identify & treat reversible cause Is patient stable ? Yes Yes •Establish AV access Immediate Synchronized •Obtain 12 Leads EKG cardioversion Is QRS narrow? (<0.12 s) Immediate I.V access Expert consultation If pulseless arrest develop, follow guideline
  • 60. Stable patient •Establish AV access •Obtain 12 Leads EKG Is QRS narrow? (<0.12 s) Narrow QRS complex Wide QRS complex Regular or not? Regular-narrow complex Irregular –narrow complex •Attempt vagal maneuver Possible AF, atrial flutter or MAT •Adenosine 6 mg iv push Consider expert consultation then 12 mg iv push Controle rate : Diltiazem, B-blocker may repeat 12 mg iv push at once Caution B-blocker in CHF, Hypotension
  • 61. Regular-narrow complex •Attempt vagal maneuver •Adenosine 6 mg iv push then 12 mg iv push may repeat 12 mg iv push at once Does rhythm convert ? Rhythm Convert Rhythm Dose not Convert = Possible SVT = Possible atrial flutter, ectopic atrial •Observe for recurrent tacchycardia, or junctional tacchycardia •Treat recurrent with adenosine or AV • Controle rate (diatiazem, b-blocker) blocking agent (diltiazem/B-blocker) • Treat underlying cause • Expert consultation During evaluation consider =6H= =5T= Hypovolumia Toxin Hypoxia Temponade Hydrogen ion Thrombosis Hypoglycemia Tension pneumothorax Hypo/hyper kalemia Trauma Hypothermia
  • 62. Wide QRS complex Regular Irregular If atrial fibrillation with aberrency If ventricular tacchycardia or uncertain • Treat as irregular narrow complex rhythm tacchycardia •Amiodarone 150 mg i.v over 10 min If preexite atrial fibrillation (AF with Repeat as needed to maximum dose 2.2 WPW) g/24 hr • Expert consultation •Prepare for synchronized cardioversion • Avoid AV nodal blocking agent If SVT with aberrency , (adenosine, digoxin, diltiazem, •Give adenosine verapamil) • Consider antiarrhythmic drug (amiodarone 150 mg iv over 10 min) If recurrent polymorphic VT • Expert consultation If torsade de point give •MgSO4 1-2 g over 5-60 min then infusion
  • 63.
  • 64. 35 yr-old woman with palpitation, light headness and stable tacchycardia. EKG as picture. An IV has been established. What drug should be administered IV? o Atropine 0.5 mg o Lidocaine 1 mg/kg o Epinephrine 2-10 µg/kg/min o Adenosine 6 mg Answer : SVT =Adenosine 6 mg
  • 65.
  • 66. WINTER Template 67 Yr-old male ไม่รู้สึกตัวมา 30 min >V/S : BP 64/24,PR 30/min หลังจากท่านได้ใส่ ท่อช่วยหายใจ เปิดเส้นเลือด ติด monitor EKG แล้ว คลื่นไฟฟ้าหัวใจเป็นดังรูปท่านคิดว่าการกระทาใด เหมาะสมที่สุด o On external pacing o Atropine 0.6 mg iv stat o 7.5 % NaHCO3 1 amp iv stat o 10% Ca-gluconate 1 amp iv stat
  • 67. WINTER Template 55 Yr-old female บ่นจุกแน่นหน้าอกที่ลิ้นปี่มา 1 ช.ม เป็นขณะพัก ประวัติว่าเคยไปตรวจที่คลินิค แพทย์บอกว่าหัวใจโต V/S : BP 140/86 PR 87/min ,regular-full peripheral pulse. EKG เป็นดังรูป ท่านจะทาอย่างไร o ให้ ASA, ISDN, Morphine o ให้ serial EKG ไปก่อน รอ cardiac enzyme o Consult cardiologist ทันที สงสัย AMI
  • 68. WINTER Template 58 Yr-old male บ่นแน่นหน้าอก หน้ามืดจะเป็นลม 30 นาที V/S BP 90/60 PR 33/min ,sweating, look anxiousness. EKG เป็นดังรูป ท่านจะทาอย่างไร o ให้ atropine 1 amp iv. stat o ให้ serial EKG รอ cardiac enzyme o Consult cardiologist ทันที สงสัย AMI o ใส่ Transcutaneous pacing
  • 69. WINTER Template 61 Yr-old male หน้ามืด ขณะนั่งรับประทานอาหาร ไม่มจุกแน่นหน้าอก แต่มีใจสั่น V/S แรกรับ ี BP 95/57 PR 42/min , irregular, sweating ถามตอบไม่รู้เรื่อง o ให้ atropine 1 amp iv. stat o ให้ serial EKG รอ cardiac enzyme o Consult cardiologist ทันที o ใส่ Transcutaneous pacing
  • 70. WINTER Template 66 Yr-old male, underlying CAD with history of coronary bypass graft. มาด้วยเป็นลมหมดสติ ไม่รู้สึกตัว BP วัดไม่ได้ ปลายมือปลายเท้าซีด เย็น o ให้ adenosine 6 mg iv stat o ให้ synchronized cardioversion 100 J o ให้ cordarone 150 mg iv stat o ให้ Defib 200 J
  • 71. 57 yr-old woman with palpitation, chest discomfort and tacchycardia. The moniter as picture. She becomes diaphoretic and BP 80/60 mmHg. The next action is o Obtain 12 lead EKG o Perform immediate electrical cardioversion o Establish IV and give sedation for electrical cardioversion o Give amiodarone 300 mg IV push Answer : VT with pulse Immediate electrical cardioversion
  • 72. • If the patient is monomorphic, unstable VT but has pulse, treat with synchronized cardioversion initial dose is 100J. and stepwise (200J, 300J, 360J)
  • 73. • 27 ปีผู้ชาย อยู่ ๆ มีอาการใจสั่น หน้ามืด จะเป็นลม เหงื่อแตก ไม่เคยเป็นเช่นนี้มาก่อน มาที่ ER ปลายมือปลายเท้าเย็น BP 120/84 PR 210 EKG เป็นดังรูป จงให้การรักษา o Adenosine 6 mg iv stat o Give amiodarone 300 mg IV push o Perform immediate Defibrillation o Establish IV and give sedation for synchronized cardioversion
  • 74. WINTER 2005 Coronary Template Syndrome Panita Worapratya Emergency Department Prince of Songkhla University
  • 75. WINTER 2005 Basic EKG for Template ACS Panita Worapratya Emergency Department Prince of Songkhla University
  • 76. EKG change during ischemia WINTER Template
  • 77. EKG change during ischemia WINTER Template
  • 78. EKG change during ischemia WINTER Template LCA origin : Lt. sinus of aortic valve
  • 79. EKG change during ischemia WINTER Template LAD : Anteroseptal Distal LAD : Anastomosis with posterior diagonal branch of RCA
  • 80. EKG change during ischemia WINTER Template LCx : Anterolateral wall
  • 81. EKG change during ischemia WINTER Template RCA : RV, inferior wall
  • 82. Basic Leads group WINTER Template Wall EKG Blood supply Inferior wall II, III, aVF RCA or LCA RV infarction II, III, aVF, V4R Prox. RCA
  • 83. Basic Leads group WINTER Template Wall EKG Blood supply Inferior wall II, III, aVF RCA or LCA RV infarction II, III, aVF, V4R Prox. RCA Inf-Lat wall II, III, aVF, V5-6 Dominant RCA or LCA
  • 84. Basic Leads group WINTER Template Wall EKG Blood supply Anterior V2-4 Mid LAD
  • 85. Basic Leads group WINTER Template Wall EKG Blood supply Anterior V2-4 Mid LAD Ant-Lat-Sep V1-6, aVL Prox LAD Lateral I, aVL,V5,6 Diagonal branch of LAD
  • 86. Basic Leads group WINTER Template Wall EKG Blood supply Anterior V2-4 Mid LAD Ant-Lat-Sep V1-6, aVL Prox LAD
  • 87. Basic Leads group WINTER Template Wall EKG Blood supply Anterior V2-4 Mid LAD Ant-Lat-Sep V1-6, aVL Prox LAD
  • 88. Basic Leads group WINTER Template Wall EKG Blood supply Anterior V2-4 Mid LAD Ant-Lat-Sep V1-6, aVL Prox LAD Lateral I, aVL,V5,6 Diagonal branch of LAD
  • 89. Basic Leads group WINTERTemplate Wall EKG Blood supply Inferior wall II, III, aVF RCA or LCA RV infarction II, III, aVF, V4R Prox. RCA Inf-Lat wall II, III, aVF, V5-6 Dominant RCA or LCA Anterior V2-4 Mid LAD Ant-Lat-Sep V1-6, aVL Prox LAD Lateral I, aVL,V5,6 Diagonal branch of LAD
  • 90. RCA or RCx WINTER Template RCA occlusion RCx occlusion • ST elevation III > II • ST elevation II > III • ST depression in Lead I • ST elevate in Lead I • Isoelectric V4R • Negative V4R
  • 91. Various cause of ST segment Deviation ST elevation WINTER ST depression Template Suggest MI Symmetric ST inversion in contiguous leads Asymmetric ST Early “Scooping or strain depression in repolarization like pattern lateral leads
  • 92. EKG Evolution in non-reperfused MI WINTER Template
  • 93. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template • Deep S wave in V1,V2 MI MI + RBBB Brugada • Tall R in V5,V6
  • 94. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada • Predominate negative QRS in V1 • QRS widening > 0.12 s • Upright QRS in Lead I, V6
  • 95. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada
  • 96. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada
  • 97. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada
  • 98. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada
  • 99. Morphology of ST elevate LVH LBB WINTER Pericarditis Hyper K+ Template MI MI + RBBB Brugada
  • 100. Morphology of ST elevate WINTER Template
  • 101. 1 Chest comfort suggest of ischemia 2 EMS careand Hosp. preparation • Moniter, ABC support, prepare for CPR & defibrillation • Administer MONA (morphine,oxygen,nitroglycerine, ASA) as needed • Obtain EKG, if ST-elevation • Notify receiving hospital • Begin fibrinolytic check list • Notify hospital to response MI. 3 Immediate ED assessment < 10 min Immediate ED general treatment • Check V/S, evaluate oxygen saturation Start O2 4 L/min, maintain O2 sat > 90% • Obtain 12 leads EKG ASA 160-325 mg (if not given by EMS) • Brief target Hx & PE NTG sublingual,spray or i.v • Review fibrinolytic check list Morphine i.v if not improved by NTG • Obtain initial cardiac marker level, E-lyte and coagulopathy • Obtain portable CXR < 30min
  • 102. 4 Review 12 Leads EKG 5 9 13 ST depression or dynamic T- Normal or nondiagnostic ST- ST elevation or new LBBB wave, strongly suspected wave change Strongly suspected STEMI ischemia Intermediate or low risk UA high risk /NSTEMI 6 10 14 Start adjunctive treatment Start adjunctive treatment as indicated as indicated Develop High or Intermediate • B-adrenergic receptor block • Nitroglycerine risk criteria (Table 3,4) • Clopidogrel • B-adrenergic blocker or • Heparin • Clopidogrel Troponin positive • Glycoprotein Iib/IIIa YES No ≥ 12hr 7 11 15 Admit to moniter and Consider admission to ED Time form onset of risk assessment (Table chest pain unit or symptoms ≤ 12 hr 3,4) monitered bed • Serial cardiac marder • Repeate EKG < 12hr • consider stress test
  • 103. 4 Review 12 Leads EKG 5 9 13 ST depression or dynamic T- Normal or nondiagnostic ST- ST elevation or new LBBB wave, strongly suspected wave change Strongly suspected STEMI ischemia Intermediate or low risk UA high risk /NSTEMI 6 Start adjunctive treatment as indicated • B-adrenergic receptor block • Clopidogrel • Heparin ≥ 12hr 7 11 Admit to moniter and Time form onset of risk assessment (Table symptoms ≤ 12 hr 3,4) < 12hr
  • 104. 7 Time form onset of symptoms ≤ 12 hr 8 Reperfusion therapy •Reperfusion goal •Door to balloon (PCI) < 90 min •Door to needle (fibrinolysis) 30min •Continue adjuctive therapy and.. • ACE-I or ARB < 24 of onset • HMG co A reductase inhibitor
  • 105. 4 Review 12 Leads EKG 5 9 13 ST depression or dynamic T- Normal or nondiagnostic ST- ST elevation or new LBBB wave, strongly suspected wave change Strongly suspected STEMI ischemia Intermediate or low risk UA high risk /NSTEMI 10 Start adjunctive treatment as indicated • Nitroglycerine • B-adrenergic blocker • Clopidogrel • Glycoprotein Iib/IIIa 11 Admit to moniter and risk assessment (Table 3,4)
  • 106. 11 Admit to moniter and risk assessment (Table 3,4) 12 High risk patient (table 3,4 for risk stratification) • Refractory ischemic chest pain • Recurrent persistent STE • Ventricular tacchycardia • Hemodynamic instability • Early invasive strategy, including PCI and revascularization for shock ≤ 48 hr. of AMI Continue ASA, heparin and other therapy as indicated • ACE-I/ ARB • HMG co A reductase inhibitor
  • 107. 4 Review 12 Leads EKG 5 9 13 ST depression or dynamic T- Normal or nondiagnostic ST- ST elevation or new LBBB wave, strongly suspected wave change Strongly suspected STEMI ischemia Intermediate or low risk UA high risk /NSTEMI 14 Start adjunctive treatment as indicated Develop High or Intermediate • Nitroglycerine risk criteria (Table 3,4) • B-adrenergic blocker or • Clopidogrel Troponin positive • Glycoprotein Iib/IIIa YES No 15 Admit to moniter and Consider admission to ED risk assessment (Table chest pain unit or 3,4) monitered bed • Serial cardiac marder • Repeate EKG • consider stress test
  • 108. 15 Consider admission to ED chest pain unit or monitered bed • Serial cardiac marder • Repeate EKG • consider stress test 16 Develop High or Intermediate risk criteria (Table 3,4) or Troponin positive 17 If no evidence of ischemia or infarction, can discharge with F/U
  • 109. Check list for STEMI fibrinolytic therapy Step 1 Chest discomfort > 15 min, < 12 hr YES EKG show STEMI or new LBBB ? stop YES Are there contraindication for fibrinolysis ? Step 2 SBP > 180 mm Hg □ YES □ NO DBP > 110 mmHg □ YES □ NO ∆ Rt. VS Lt. arm SBP > 15 mmHg □ YES □ NO History of structural CNS disease □ YES □ NO Significant closed head or facial trauma < 3 mo □ YES □ NO Recent major surgery or trauma or GU/GI bleed < 6 wk □ YES □ NO Bleeding or clotting problem □ YES □ NO CPR > 10 min □ YES □ NO Pregnant female □ YES □ NO Serious systemic disease □ YES □ NO
  • 110. Check list for STEMI fibrinolytic therapy Are there contraindication for fibrinolysis ? Step 2 NO Step 3 Is a pateint any high risk ? If any of following check “YES” , consider PCI HR ≥ 100/min and SBP < 100 mmHg □ YES □ NO Pulmonary edmema (rale) □ YES □ NO Sign of shock (cool, clamy) □ YES □ NO Contraindication for fibrinolytid therapy □ YES □ NO
  • 111. Table 3 : Likely hood of ischemic etiology (short term risk) Part I : Chest pain patient without ST segment change Likelihood of ischemic etiology A : High likelihood B : Intermediate likelihood C : Low likelihood Any of following No A with any of following No A & B with any of following History • Chief complaint of Lt. arm pain or discomfort plus Current pain reproduce pain of prior pain document angina and Known CAD including MI Physical Exam • Transient MR • Hypotension • Diaphoresis • Pulmonary edema or rale EKG • New (or persume new) transient ST deviation (>0.5 mm) or T wave inversion (> 2 mm) with symptoms Cardiac marker • Elevate troponin I or T • Elevate CK-MB
  • 112. Table 3 : Likely hood of ischemic etiology (short term risk) Part I : Chest pain patient without ST segment change Likelihood of ischemic etiology A : High likelihood B : Intermediate likelihood C : Low likelihood Any of following No A with any of following No A & B with any of following History • Chief complaint of Lt. arm • Chief complaint is Lt. arm pain pain or discomfort plus or dyscomfort Current pain reproduce pain • Age > 70 yr. of prior pain document • Male sex angina and Known CAD • Diabetic mellitus including MI Physical Exam • Transient MR • Extravascular disease • Hypotension • Diaphoresis • Pulmonary edema or rale EKG • New (or persume new) • Fixd Q wave transient ST deviation (>0.5 • Abnormal ST segment or T mm) or T wave inversion (> 2 wave that are not new mm) with symptoms Cardiac marker • Elevate troponin I or T • Normal • Elevate CK-MB
  • 113. Table 3 : Likely hood of ischemic etiology (short term risk) Part I : Chest pain patient without ST segment change Likelihood of ischemic etiology A : High likelihood B : Intermediate likelihood C : Low likelihood Any of following No A with any of following No A & B with any of following History • Chief complaint of Lt. arm • Chief complaint is Lt. arm pain • Probable ischemic symptoms pain or discomfort plus or dyscomfort • Recent cocaine use Current pain reproduce pain • Age > 70 yr. of prior pain document • Male sex angina and Known CAD • Diabetic mellitus including MI Physical Exam • Transient MR • Extravascular disease • Chest discomfort reproduce • Hypotension by palpation • Diaphoresis • Pulmonary edema or rale EKG • New (or persume new) • Fixd Q wave • Normal EKG or T wave transient ST deviation (>0.5 • Abnormal ST segment or T flattening or T wave inversion mm) or T wave inversion (> 2 wave that are not new in leads which dominant R mm) with symptoms wave Cardiac marker • Elevate troponin I or T • Normal • Normal • Elevate CK-MB
  • 114. Table 3 : Likely hood of ischemic etiology (short term risk) Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high or intermediate likelihood of ischemia (column A, B in Part I) High risk Intermediate risk Low risk Any of the following Any of the following Any of the following History • Accelerating tempo of ischemic symptoms over prior 48 hr. Character of pain • Prolong continue > 20 min of rest pain Physical exam • Age > 75 yr • Pulmonary edema secondary to ischemia • New or worse MR • Hypotension, brady/tacchycardia • S3 gallops or new or worsening rale EKG • Transient ST segment deviation (≥ 0.5 mm with rest agina) • Persume new LBBB • Sustain VT Cardiac marker • Elevate cardiac troponin • Elevate CK-MB
  • 115. Table 3 : Likely hood of ischemic etiology (short term risk) Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high or intermediate likelihood of ischemia (column A, B in Part I) High risk Intermediate risk Low risk Any of the following Any of the following Any of the following History • Accelerating tempo of ischemic • Prior MI or symptoms over prior 48 hr. • Peripheral artery disease or • Cerebrovascular disease or • CABG, prior ASA use Character of pain • Prolong continue > 20 min of rest • Prolong > 20 min rest angina is now pain resolved (moderate to high likely hood of CAD) • Rest angina (<20 min) or relieved by rest or sublingual nitroglycerine Physical exam • Age > 75 yr • Age > 70 yr • Pulmonary edema secondary to ischemia • New or worse MR • Hypotension, brady/tacchycardia • S3 gallops or new or worsening rale EKG • Transient ST segment deviation (≥ • T wave inversion ≥ 2 mm. 0.5 mm with rest agina) • Pathologic T wave or Q wave that • Persume new LBBB are not new • Sustain VT Cardiac marker • Elevate cardiac troponin • Any or above , plus normal • Elevate CK-MB
  • 116. Table 3 : Likely hood of ischemic etiology (short term risk) Part II : Risk of death or non fatal MI over the short term in Patient with chest pain with high or intermediate likelihood of ischemia (column A, B in Part I) High risk Intermediate risk Low risk Any of the following Any of the following Any of the following History • Accelerating tempo of ischemic • Prior MI or symptoms over prior 48 hr. • Peripheral artery disease or • Cerebrovascular disease or • CABG, prior ASA use Character of pain • Prolong continue > 20 min of rest • Prolong > 20 min rest angina is now • New onset functional angina (Class pain resolved (moderate to high likely III or IV) in past 2 wk. without hood of CAD) prolong rest pain (but with • Rest angina (<20 min) or relieved moderate to high likelihood of CAD) by rest or sublingual nitroglycerine Physical exam • Age > 75 yr • Age > 70 yr • Pulmonary edema secondary to ischemia • New or worse MR • Hypotension, brady/tacchycardia • S3 gallops or new or worsening rale EKG • Transient ST segment deviation (≥ • T wave inversion ≥ 2 mm. • Normal or unchanged EKG during 0.5 mm with rest agina) • Pathologic T wave or Q wave that an episode of chest discomfort • Persume new LBBB are not new • Sustain VT Cardiac marker • Elevate cardiac troponin • Any or above , plus normal • Normal • Elevate CK-MB
  • 117. Table 4 : TIMI risk score for patient with UA and NSTEMI Risk factor of CAD • Family Hx of CAD Predictor variable • HT • Hypercholesteralemia • D.M Age > 65 year • Current smoker ≥ 3 risk factor of CAD ASA used in Last 7 days ≥ 2 angina event in last 24 hr Recent , severe symptoms of angina Elevated cardiac marker ST deviation ≥ 0.5 mm. Prior coronary a. stenosis > 50% •ST depression > 0.5 mm is significant •Transient ST deviation > 0.5 mm < 20 min is high risk •STE > 1 mm (>20 min) = STEMI
  • 118. Table 4 : TIMI risk score for patient with UA and NSTEMI Calculated Risk of ≥ 1 Risk status TIMI risk primary end score point in 14 days 0-2 5-8% Low 3-4 13-20% Intermediate 5 26% High 6 or 7 41% High Predictor variable Age > 65 year ≥ 3 risk factor of CAD ASA used in Last 7 days Recent , severe symptoms of angina Elevated cardiac marker ST deviation ≥ 0.5 mm. Prior coronary a. stenosis > 50%
  • 119. Case Presentation WINTER • ชายอายุ 42 ปี : 3 วันมีอาการใจสั่น แน่นหน้าอก ไม่สัมพันธ์กับการออกกาลัง Template ก่อนมาร.พ เพื่อนนาส่งร.พ อาการเป็น ๆ หาย ๆ เจ็บหน้าอกครั้งสุดท้าย 45 นาที V/S : BT 36 c PR 40/min , RR 20/min, BP 69/37 mmHg Consciousness พูดเป็นคา ทาตามสั่งบ้าง ไม่ทาตามสั่งบ้าง เหงื่อแตก มือเท้าเย็น บ่นแน่นหน้าอก
  • 120. Case Presentation A : Anxiousness. WINTER Template B : Lung is clear . O2 sat วัดไม่ได้ C : PR 40/min,irregular rate, no murmur. Poor peripheral pluse, acrocyanosis. D : E3V5M5-6 No moter weakness.
  • 121. Case Presentation WINTER Template
  • 122. Case Presentation WINTER Template
  • 123. Case Presentation WINTER Template
  • 124. Case Presentation Initial management WINTER Template A : None B : O2 cannular 3 LPM C : Moniter EKG, I.V access ส่ง Lab + cardiac enzyme 0.9 % NSS iv load 1000 ml iv freee flow 300 ml Atropine 1 amp iv stat On External pacemaker
  • 125. Case Presentation WINTER Template หลัง Load fluid ครบ 300 ml และให้ atropine 1 amp V/S : PR 65/min BP 72/47 , O2 sat 100% เริ่มถามตอบไม่รู้เรื่อง มองไม่สื่อความหมาย Mx : ET-Tube No 7.5 ขีด 23 cm. EKG เป็นดังรูป (next slide)
  • 126. Case Presentation WINTER หลัง Load fluid ครบ 300 ml และให้ atropine 1 amp Template V/S : PR 65/min BP 72/47 , O2 sat 100% เริ่มถามตอบไม่รู้เรื่อง มองไม่สื่อความหมาย Mx : ET-Tube No 7.5 ขีด 23 cm.
  • 127. Case Presentation WINTER Template
  • 128. Case Presentation ท่านจะทาอย่างไรต่อไป WINTER • At 19.37 หลังใส่ ET-Tube คนไข้เริ่ม unconsciousness , คลา pulse ไม่ได้ Template
  • 129. Case Presentation WINTER • หลังจาก CPRไปได้ 2 นาที ให้ adrenaline run q 3 min คลื่นไฟฟ้า Template หัวใจเป็นดังรูป ท่านจะทาอย่างไรต่อไป
  • 130. Case Presentation WINTER • ได้ทา defibrillation x 3 ครั้ง EKG ยังคงเป็นเช่นนี้ ท่านจะทาอย่างไรต่อไป Template
  • 131. Case Presentation ท่านจะทาอย่างไรต่อไป WINTER • หลังจากท่าน ได้ check lead, ขยาย amplitude แล้ว EKG เป็นดังนี้ Template
  • 132. Case Presentation WINTER Template หลังจากท่านได้ Defibrillation แล้ว EKG เป็นดังนี้ ท่านจะทาอย่างไร o Atropine 1 amp iv stat o External pacemaker o Transfer to ICU o Load 0.9% NSS
  • 133. WINTER 2005 Thank You Template Panita Worapratya Emergency Department Prince of Songkhla University
  • 134.
  • 135.
  • 136. Common cause of ST depression
  • 138. 04 Bullet points are like this Text and lines are like this Hyperlinks like this Visited hyperlinks like this Text box PowerPoint styles
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  • 140. 4 Review 12 Leads EKG 5 9 13 ST depression or dynamic T- Normal or nondiagnostic ST- ST elevation or new LBBB wave, strongly suspected wave change Strongly suspected STEMI ischemia Intermediate or low risk UA high risk /NSTEMI 6 10 14 Start adjunctive treatment Start adjunctive treatment as indicated as indicated Develop High or Intermediate • B-adrenergic receptor block • Nitroglycerine risk criteria (Table 3,4) • Clopidogrel • B-adrenergic blocker or • Heparin • Clopidogrel Troponin positive • Glycoprotein Iib/IIIa YES No ≥ 12hr 7 11 15 Admit to moniter and Consider admission to ED Time form onset of risk assessment (Table chest pain unit or symptoms ≤ 12 hr 3,4) monitered bed • Serial cardiac marder • Repeate EKG < 12hr • consider stress test