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DIGESTION
B M Subramanya Swamy M.Sc. B.Ed.
CIE Co ordinator & Examination Officer
Kanaan Global School
Jakarta
Indonesia
subramanyaswamy1591978@gmail.com
DIGESTION
Digestion
Process by which the body breaks down food
(carbohydrates, fats and proteins) into
simpler substances
These substances are absorbed and used by
cells in the body
Types of digestion
Types of digestion

Process

Mechanical



Mastication (chewing, mashing and breaking)
into smaller particles
 In the mouth, teeth cuts and grinds food.
Rolling action of tongue and secretion of
saliva rolls food into bolus
 Bolus is swallowed and transported through
pharynx to stomach by waves of rhythmic
contraction called peristalsis

Chemical



Changing food into smaller particles through
action of enzyme
 Involves hydrolysis (addition of water)
e.g. amylase converts carbohydrates into
simple sugars
THE HUMAN DIGESTIVE SYSTEM
THE WORKING OF HUMAN
DIGESTIVE SYSTEM
MOUTH
Functions : analysis material before swallowing, mechanical processing
by the teeth, tongue and palatal surfaces, lubricating, limited
digestion
TEETH
Functions :
 Grinding action (mastication) breaks down food
 Expose large area for enzyme action

child
adult
TONGUE
Functions :
 Rolls food into bolus
SALIVARY GLANDS
Secretions
Saliva contains:
 Water

Functions

Moisten and soften food
 As solvent and for hydrolysis
 Mucus
 Sticks food together to form bolus
maltose
 Salivary amylase  Starch

PHARYNX
Function : involuntary action pushes bolus into
oesophagus

Nasal cavity
Palate
Oral cavity

Tongue
Mandible

Pharynx
OESOPHAGUS
Functions :
• Walls made up of circular and longitudinal muscles
• Peristalsis transports food to the stomach

CARDIAC SPHINCTER
Function :
• Controls entry of food into the stomach
The swallowing process
Peristalsis
Characteristic

 Automatic

Length of alimentary canal made up circular and
longitudinal muscle
 Alternate contraction and relaxation of muscle


Result

Movement of food down the canal
Peristalsis
STOMACH
Secretions

Functions

Gastric juice

Muscular walls churn food into chyme
Stored food for 2 – 6 hours
Absorbs glucose and alcohol

Hydrochloric acid

Acidic medium (pH 1) for enzyme action
Kills bacteria brought in with food
Activates enzymes

Water

As solvent and for hydrolysis

Mucus

Protects stomach wall from acidic gastric juice
Lubricant for movement of food in the stomach

Pepsin

Protein

Rennin

Converts protein into insoluble curds (coagulates
milk) for hydrolysis of pepsin.

polypeptides
PHYLORIC SPHINCTER
Function : controls entry of food into duodenum
Stomach
Esophagus

Pylorus

Fundus
Body

Pyloric Den

Duodenum
Anatomy of the stomach
PANCREAS
Secretions

Functions

Pancreatic juice

Hydrolysis of food in duodenum

Amylase

Starch → maltose

Trypsin

Polypeptides → peptides

Lipase

Fats → fatty acids and glycerol

Water

As solvent for hydrolysis

Insulin

Excess glucose is converted to
glycerol in the liver
LIVER
Secretions
Dark green bile

Functions
 Provides alkaline pH
 Bile is stored in the gall bladder
 Emulsifies fats, provides increased
surface area for action of lipase
 Neutralise acidic chyme
Anatomy of the liver
Anatomy of the liver
SMALL INTESTINE
Secretion
Function

Intestinal juice
Final stage of digestion pH 8 (alkaline)

DUODENUM
Secretions

Erepsin
Lactase
Sucrase
Maltase
Water

Functions

Peptides → amino acids
Lactose → glucose and galactose
Sucrose → glucose and fructose
Maltose → sucrose
As solvent and for hydrolysis
JEJUNUM
Function : absorption of food

ILEUM
Function : absorption of food
The region of small intestine
The intestinal wall
The intestinal wall
The intestinal wall
LARGE INTESTINE
Function : absorption of water from undigested food

CAECUM AND APPENDIX
Function :
 Vestigial organs with no particular function
 Forms junction of small and large intestine

COLON
Secretion
Mucus

Function


Peristalsis compact undigested food to
form faeces
 Lubricates faeces and protects wall from
digestive juice
Large intestine
RECTUM
Function : stored faeces before defaecation
ANUS
Function : regulate emptying of rectum
What goes in must come out!
Comparison of human and herbivore digestive system
Human

Herbivore

Food

Carbohydrates, Mainly plant proteins
fats and proteins and cellulose

Alimentary canal
Stomach

Short
Simple

Long

Caecum

Very small

Large caecum with
cellulase to break down
cellulose to glucose



Several chambers
 Contains bacteria for
digestion of cellulose
ABSORPTION OF DIGESTED FOOD
 Nutrients from digested food must be moved from intestines
to the bloodstream
 This process is called absorption
 Almost all of the digested food is absorbed in the ileum
 The small intestine is about 6 -7 m long
 Water soluble end – products of digestion enter the blood
system by diffusion
 Fatty acids and glycerol are absorbed by the lacteals
 Once inside, fatty acids recombine with glycerol to form
globules of fat
 They are carried by the lymphatic system to the veins
Structure of the Villi in the Small Intestine
Structure of a villus
Adaptation of the ileum to absorb digested food
Features
Length

Adaptation
Longest part of the alimentary canal

Internal surface area Internal walls are folded to increase surface area for
absorption

Villi

Further increase surface area for absorption

Microvilli

Villus covered with epithelial cells
The plasma membrane of each cell has minute finger – like
projections (microvilli)
Further increase surface area

Movement

Villi move back and forth independently
Motion faster after meals
Absorption rate increases

Membrane

Absorption across membrane
Either by diffusion or active transport

capillary network

Dense capillary network close to epithelium
Carry away absorbed food particles quickly
Maintain concentration gradient between ileum and blood
capillaries to aid diffusion
ASSIMILATION
Assimilation  uptake and use of food within the body

Fate of end products of digestion
End – product

Fate

Glucose



Excess is converted to glycogen (insoluble granules)
and stored in the liver
 Converted back to glucose when body needs energy
and blood sugar level is low
 Further excess of glucose is stored as fats in the
adipose tissue
 Used in cellular respiration

Fats



Part of it stored as fats in adipose tissue
 Used in synthesis of cell membrane
 Utilised in respiration when glucose and glycogen is
used up
 Fats stored under skin and around organs act as
energy store and insulation
Fate of end products of digestion
End – product

Fate

Amino acids



Synthesis of proteins, enzymes and hormones
 For growth and development
 Excess amino acids are not stored in the body
 It is broken down and deaminated in the liver to form
ammonia and glycogen (glycogen is stored in the
liver)

Egestion



In the large intestine water and vitamins (synthesised
by bacteria) compact undigested food to form faeces
 Propelled along colon and rectum
LIVER
• Structure
 Large, reddish brown organ
 Located just beneath the diaphragm and
overlaps the stomach
 Plays an important role in metabolism,
homeostasis and excretion
• Anatomy
• Vessels associated with the liver
Vessels

Function

Hepatic portal vein



Hepatic artery

Carries oxygenated blood to liver

Hepatic vein

Carries blood containing waste
products away from liver

Blood capillaries of villi join to
form the hepatic portal vein
 Carries blood containing end
products of digestion from ileum
to liver
• Function of the liver
Function

Mode of action

Metabolism of glucose



Regulates the blood sugar concentration in
the body
 Excess sugars stored as glycogen granules
 This occurs in the presence of insulin
 When plasma sugar levels fall, glucagon
converts glycogen to glucose

Metabolism of amino acids



Regulates amount of amino acids in the
body
 Excess amino acids cannot be stored
 Converted during deamination into glucose
and urea
 Excess glucose is stored as glycogen
 Urea is excreted
Function

Mode of action

Production of bile



Produces bile, which is used in digestion

Storage of iron



Excretion of the bile
pigment



Synthesis of plasma
proteins



Storage of vitamins



Stores vitamin A and D

Reservoir for blood



Blood spaces and network of blood
capillaries hold a large volume of blood

Stores iron from breakdown of haemoglobin
 Used in the synthesis of new haemoglobin
Haemoglobin is broken down into bile
pigments biliverdin and bilirubin
 Both pigments are excreted into duodenum
as bile pigments
Synthesises plasma protein (fibrinogen,
serum globulin and serum) from amino acids
 They are responsible for the clotting of blood
Function

Mode of action

Source of heat energy



Metabolically active, producing a large
amount of heat energy to replace that lost by
the body
 Heat distributed to all parts of the body

Detoxification



Toxins produced bacteria in large intestines
are absorbed and converted to harmless
substances in the liver
 Liver removes about 95% of alcohol from
blood
 Alcohol oxidised in the liver to energy
 May also be converted to fats
 The other 5% lost as sweat, urine and
during breathing
DENTITION
STRUCTURE
Mechanical digestion is carried on in the mouth by the action
of the teeth and the tongue.
child
adult
Vertical section of molar

Crown

Enamel
Dentine
Gum
Pulp cavity containing
nerves and blood
vessels

Root
Jaw bone
Cementum
Tooth structure and function
Tooth structure

Components

Function

Enamel

Non – living layer of
hard calcium salts

Dentine

Softer bone – like layer Acts as a shock absorber

Pulp cavity

Contains tooth cells,
nerves and blood
capillaries

Tooth

Cement

Thin layer of bone –
like material

Covers

Root opening

Pathway for blood
capillaries and nerves

For

Protects

dentine
Forms a hard biting surface
cells divide to form
dentine
Supply food and oxygen to
cells
dentine of root
Holds root in socket
blood supply, growth and
replacement of tooth
Nerves carry messages to
and from brain
Tooth structure

Components

Function

Jaw bone with socket

Bone made of calcium Tooth fits into socket
phosphate
of jaw bone

Incisor

Single root
Sharp cutting edge

Biting of pieces of
food

Canine

Single root
Sharp and pointed

Tearing, seizing food

Premolar and molar

Wide and flat surface
Has cusps (points) or
ridges

Crushing and grinding
food
Different types of dental formula
Omnivore

Carnivore

Herbivore

Dental
formula

i:2

c:1

pm : 2

m :3

i:3

c :1

pm : 4

m: 2

i:0

c:0

pm: 3

m: 3

2

1

2

3

3

1

4

3

3

1

3

3

Mode of
nutrition

Plant and animal

Animal

Plant

Incisor

Chisel shaped

Sharp and pointed



Canine

About the same size as
incisors

Long, pointed, curved



Diastema

X

X

Upper incisor absent
 Small lower incisor,
bites against upper
horny pad
Upper canines
absent
 Lower canines have
sharp edges, bites
against upper horny
pad


Omnivore
Premolar / molar

Surface has small
cusps

Carnassial teeth

Carnivore
Surface has sharp,
pointed edges

X

Herbivore
Surface flattened
with small cusps



X

Feeding action



Upper and lower
 Upper and lower
jaw meet
jaw move up and
 Grind food with
down
lateral movements  Scissor – like
(side to side) of
action
lower jaw
 Tight jaw
attachment



Example

Adult human

Goat

Dog

Upper and lower
jaw meet
 Grind food with
lateral movements
(side to side) of
lower jaw
 Loose jaw
attachment
Tooth Decay
 Dental plaque is the result of bacteria acting on food or sugar
stuck on teeth
 Tartar is the hard deposit on the teeth caused by bacterial
plaque, calcium phosphate and calcium carbonate
 It leads to gum disease resulting in gum irritation and swollen
gum
 As the bacteria in plaque grow, it produces acid in the layer of
plaque
 This acid destroys the enamel and later, the dentine layer of
the teeth
 When the decay (cavity) spreads to the pulp cavity, the entire
tooth is affected
 The result is painful and swollen gum
Prevention of gum disease
Prevention

Action

Taking food rich in calcium,
phosphorous and vitamin D

Form strong teeth

Drinking water or using toothpaste
with added fluoride

Hardens tooth surface
Makes them less susceptible to
acids

Brushing teeth regularly

Remove food particles in teeth

Flossing teeth

Remove food lodged between
teeth

Reducing sugar in the diet

Reduce bacterial affect

Regular dental check up

Monitor health of teeth

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Digestion IGCSE

  • 1. DIGESTION B M Subramanya Swamy M.Sc. B.Ed. CIE Co ordinator & Examination Officer Kanaan Global School Jakarta Indonesia subramanyaswamy1591978@gmail.com
  • 3. Digestion Process by which the body breaks down food (carbohydrates, fats and proteins) into simpler substances These substances are absorbed and used by cells in the body
  • 4. Types of digestion Types of digestion Process Mechanical  Mastication (chewing, mashing and breaking) into smaller particles  In the mouth, teeth cuts and grinds food. Rolling action of tongue and secretion of saliva rolls food into bolus  Bolus is swallowed and transported through pharynx to stomach by waves of rhythmic contraction called peristalsis Chemical  Changing food into smaller particles through action of enzyme  Involves hydrolysis (addition of water) e.g. amylase converts carbohydrates into simple sugars
  • 6. THE WORKING OF HUMAN DIGESTIVE SYSTEM
  • 7. MOUTH Functions : analysis material before swallowing, mechanical processing by the teeth, tongue and palatal surfaces, lubricating, limited digestion
  • 8. TEETH Functions :  Grinding action (mastication) breaks down food  Expose large area for enzyme action child adult
  • 10. SALIVARY GLANDS Secretions Saliva contains:  Water Functions Moisten and soften food  As solvent and for hydrolysis  Mucus  Sticks food together to form bolus maltose  Salivary amylase  Starch 
  • 11. PHARYNX Function : involuntary action pushes bolus into oesophagus Nasal cavity Palate Oral cavity Tongue Mandible Pharynx
  • 12. OESOPHAGUS Functions : • Walls made up of circular and longitudinal muscles • Peristalsis transports food to the stomach CARDIAC SPHINCTER Function : • Controls entry of food into the stomach
  • 14. Peristalsis Characteristic  Automatic Length of alimentary canal made up circular and longitudinal muscle  Alternate contraction and relaxation of muscle  Result Movement of food down the canal
  • 16. STOMACH Secretions Functions Gastric juice Muscular walls churn food into chyme Stored food for 2 – 6 hours Absorbs glucose and alcohol Hydrochloric acid Acidic medium (pH 1) for enzyme action Kills bacteria brought in with food Activates enzymes Water As solvent and for hydrolysis Mucus Protects stomach wall from acidic gastric juice Lubricant for movement of food in the stomach Pepsin Protein Rennin Converts protein into insoluble curds (coagulates milk) for hydrolysis of pepsin. polypeptides
  • 17. PHYLORIC SPHINCTER Function : controls entry of food into duodenum
  • 19. Anatomy of the stomach
  • 20. PANCREAS Secretions Functions Pancreatic juice Hydrolysis of food in duodenum Amylase Starch → maltose Trypsin Polypeptides → peptides Lipase Fats → fatty acids and glycerol Water As solvent for hydrolysis Insulin Excess glucose is converted to glycerol in the liver
  • 21.
  • 22. LIVER Secretions Dark green bile Functions  Provides alkaline pH  Bile is stored in the gall bladder  Emulsifies fats, provides increased surface area for action of lipase  Neutralise acidic chyme
  • 23. Anatomy of the liver
  • 24. Anatomy of the liver
  • 25. SMALL INTESTINE Secretion Function Intestinal juice Final stage of digestion pH 8 (alkaline) DUODENUM Secretions Erepsin Lactase Sucrase Maltase Water Functions Peptides → amino acids Lactose → glucose and galactose Sucrose → glucose and fructose Maltose → sucrose As solvent and for hydrolysis
  • 26. JEJUNUM Function : absorption of food ILEUM Function : absorption of food
  • 27. The region of small intestine
  • 31. LARGE INTESTINE Function : absorption of water from undigested food CAECUM AND APPENDIX Function :  Vestigial organs with no particular function  Forms junction of small and large intestine COLON Secretion Mucus Function  Peristalsis compact undigested food to form faeces  Lubricates faeces and protects wall from digestive juice
  • 33. RECTUM Function : stored faeces before defaecation ANUS Function : regulate emptying of rectum
  • 34. What goes in must come out!
  • 35. Comparison of human and herbivore digestive system Human Herbivore Food Carbohydrates, Mainly plant proteins fats and proteins and cellulose Alimentary canal Stomach Short Simple Long Caecum Very small Large caecum with cellulase to break down cellulose to glucose  Several chambers  Contains bacteria for digestion of cellulose
  • 36. ABSORPTION OF DIGESTED FOOD  Nutrients from digested food must be moved from intestines to the bloodstream  This process is called absorption  Almost all of the digested food is absorbed in the ileum  The small intestine is about 6 -7 m long  Water soluble end – products of digestion enter the blood system by diffusion  Fatty acids and glycerol are absorbed by the lacteals  Once inside, fatty acids recombine with glycerol to form globules of fat  They are carried by the lymphatic system to the veins
  • 37. Structure of the Villi in the Small Intestine
  • 38. Structure of a villus
  • 39. Adaptation of the ileum to absorb digested food Features Length Adaptation Longest part of the alimentary canal Internal surface area Internal walls are folded to increase surface area for absorption Villi Further increase surface area for absorption Microvilli Villus covered with epithelial cells The plasma membrane of each cell has minute finger – like projections (microvilli) Further increase surface area Movement Villi move back and forth independently Motion faster after meals Absorption rate increases Membrane Absorption across membrane Either by diffusion or active transport capillary network Dense capillary network close to epithelium Carry away absorbed food particles quickly Maintain concentration gradient between ileum and blood capillaries to aid diffusion
  • 40. ASSIMILATION Assimilation  uptake and use of food within the body Fate of end products of digestion End – product Fate Glucose  Excess is converted to glycogen (insoluble granules) and stored in the liver  Converted back to glucose when body needs energy and blood sugar level is low  Further excess of glucose is stored as fats in the adipose tissue  Used in cellular respiration Fats  Part of it stored as fats in adipose tissue  Used in synthesis of cell membrane  Utilised in respiration when glucose and glycogen is used up  Fats stored under skin and around organs act as energy store and insulation
  • 41. Fate of end products of digestion End – product Fate Amino acids  Synthesis of proteins, enzymes and hormones  For growth and development  Excess amino acids are not stored in the body  It is broken down and deaminated in the liver to form ammonia and glycogen (glycogen is stored in the liver) Egestion  In the large intestine water and vitamins (synthesised by bacteria) compact undigested food to form faeces  Propelled along colon and rectum
  • 42. LIVER • Structure  Large, reddish brown organ  Located just beneath the diaphragm and overlaps the stomach  Plays an important role in metabolism, homeostasis and excretion
  • 44. • Vessels associated with the liver Vessels Function Hepatic portal vein  Hepatic artery Carries oxygenated blood to liver Hepatic vein Carries blood containing waste products away from liver Blood capillaries of villi join to form the hepatic portal vein  Carries blood containing end products of digestion from ileum to liver
  • 45. • Function of the liver Function Mode of action Metabolism of glucose  Regulates the blood sugar concentration in the body  Excess sugars stored as glycogen granules  This occurs in the presence of insulin  When plasma sugar levels fall, glucagon converts glycogen to glucose Metabolism of amino acids  Regulates amount of amino acids in the body  Excess amino acids cannot be stored  Converted during deamination into glucose and urea  Excess glucose is stored as glycogen  Urea is excreted
  • 46. Function Mode of action Production of bile  Produces bile, which is used in digestion Storage of iron  Excretion of the bile pigment  Synthesis of plasma proteins  Storage of vitamins  Stores vitamin A and D Reservoir for blood  Blood spaces and network of blood capillaries hold a large volume of blood Stores iron from breakdown of haemoglobin  Used in the synthesis of new haemoglobin Haemoglobin is broken down into bile pigments biliverdin and bilirubin  Both pigments are excreted into duodenum as bile pigments Synthesises plasma protein (fibrinogen, serum globulin and serum) from amino acids  They are responsible for the clotting of blood
  • 47. Function Mode of action Source of heat energy  Metabolically active, producing a large amount of heat energy to replace that lost by the body  Heat distributed to all parts of the body Detoxification  Toxins produced bacteria in large intestines are absorbed and converted to harmless substances in the liver  Liver removes about 95% of alcohol from blood  Alcohol oxidised in the liver to energy  May also be converted to fats  The other 5% lost as sweat, urine and during breathing
  • 48. DENTITION STRUCTURE Mechanical digestion is carried on in the mouth by the action of the teeth and the tongue.
  • 50. Vertical section of molar Crown Enamel Dentine Gum Pulp cavity containing nerves and blood vessels Root Jaw bone Cementum
  • 51. Tooth structure and function Tooth structure Components Function Enamel Non – living layer of hard calcium salts Dentine Softer bone – like layer Acts as a shock absorber Pulp cavity Contains tooth cells, nerves and blood capillaries Tooth Cement Thin layer of bone – like material Covers Root opening Pathway for blood capillaries and nerves For Protects dentine Forms a hard biting surface cells divide to form dentine Supply food and oxygen to cells dentine of root Holds root in socket blood supply, growth and replacement of tooth Nerves carry messages to and from brain
  • 52. Tooth structure Components Function Jaw bone with socket Bone made of calcium Tooth fits into socket phosphate of jaw bone Incisor Single root Sharp cutting edge Biting of pieces of food Canine Single root Sharp and pointed Tearing, seizing food Premolar and molar Wide and flat surface Has cusps (points) or ridges Crushing and grinding food
  • 53. Different types of dental formula Omnivore Carnivore Herbivore Dental formula i:2 c:1 pm : 2 m :3 i:3 c :1 pm : 4 m: 2 i:0 c:0 pm: 3 m: 3 2 1 2 3 3 1 4 3 3 1 3 3 Mode of nutrition Plant and animal Animal Plant Incisor Chisel shaped Sharp and pointed  Canine About the same size as incisors Long, pointed, curved  Diastema X X Upper incisor absent  Small lower incisor, bites against upper horny pad Upper canines absent  Lower canines have sharp edges, bites against upper horny pad 
  • 54. Omnivore Premolar / molar Surface has small cusps Carnassial teeth Carnivore Surface has sharp, pointed edges X Herbivore Surface flattened with small cusps  X Feeding action  Upper and lower  Upper and lower jaw meet jaw move up and  Grind food with down lateral movements  Scissor – like (side to side) of action lower jaw  Tight jaw attachment  Example Adult human Goat Dog Upper and lower jaw meet  Grind food with lateral movements (side to side) of lower jaw  Loose jaw attachment
  • 55. Tooth Decay  Dental plaque is the result of bacteria acting on food or sugar stuck on teeth  Tartar is the hard deposit on the teeth caused by bacterial plaque, calcium phosphate and calcium carbonate  It leads to gum disease resulting in gum irritation and swollen gum  As the bacteria in plaque grow, it produces acid in the layer of plaque  This acid destroys the enamel and later, the dentine layer of the teeth  When the decay (cavity) spreads to the pulp cavity, the entire tooth is affected  The result is painful and swollen gum
  • 56. Prevention of gum disease Prevention Action Taking food rich in calcium, phosphorous and vitamin D Form strong teeth Drinking water or using toothpaste with added fluoride Hardens tooth surface Makes them less susceptible to acids Brushing teeth regularly Remove food particles in teeth Flossing teeth Remove food lodged between teeth Reducing sugar in the diet Reduce bacterial affect Regular dental check up Monitor health of teeth