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The UK development of Industrial Biotechnology and Bioenergy in the context of the global Bioeconomy
Copyright © NNFCC 2014. 
the set of economic activities relating to the invention, development, production and use of biological products and processes. 
improve health outcomes, boost the productivity of agriculture and industrial processes, and enhance environmental sustainability. 
Source - OECD 
Biological Tools 
Biological Raw Materials 
The Bioeconomy 
Biobased 
Biotech
Copyright © NNFCC 2014. 
The value of biomass 
Biomass 
Functional content 
Carbon 
content 
Energy 
content 
Materials 
Chemicals 
Liquid & Gaseous Fuels 
Heat & Power 
Biorefinery operation 
Stranded assets 
Food, Feed & Medicine 
Cascading use
Copyright © NNFCC 2014. 
Attractive because it’s inherently circular 
http://www.wageningenur.nl/en/Expertise-Services/Research-Institutes/food-biobased-research/Expertise-areas/Biorefinery.htm
Copyright © NNFCC 2014. 
A major global employer
Copyright © NNFCC 2014. 
A mechanism to drive sustainable development covering Environmental, Economic and Social policy. Today’s bioeconomy in Europe 
•is worth an estimated €2 trillion 
•accounts for 22 million jobs 
•9% of total employment in the EU Each euro invested in EU-funded bioeconomy research and innovation is estimated to trigger €10 of value added in bioeconomy sectors by 2025. 
EUROPEAN BIOECONOMY 
Innovating for Sustainable Growth 
A Bioeconomy for Europe 
February 2012
Copyright © NNFCC 2014. 
Bio-based value propositions 
•New or enhanced product performance (in use phase or wider life cycle) 
•Lower cost production routes 
•Consumer desire for environmentally friendly products 
•Value created through policy intervention
Copyright © NNFCC 2014. 
Cost to develop and win marketing approval for a new drug is $2.6 billion 1 
1) Source: Tufts CSDD 
http://www.firstwordpharma.com/node/1246255#axzz3KByBqK7a 
Clear functional value in biopharma
Copyright © NNFCC 2014. 
Emotional value
Copyright © NNFCC 2014. 
Changing monetary cost base 
0 
50 
100 
150 
200 
250 
300 
Commodity Agricultural Raw Materials 
Commodity Food 
Crude Oil
Copyright © NNFCC 2014. 
Source: World Meteorological Organisation 
Policy intervention
Copyright © NNFCC 2014. 
Innovation 
Research 
Development 
Pilot 
Demonstration 
Commercialisation 
Technology Valley 
Commercialisation Valley 
Knowledge ≠ Invention ≠ Innovation
Copyright © NNFCC 2014. 
VISION UK bioscience research delivering products & processes key to the bioeconomy and driving economic growth for the UK and worldwide
Copyright © NNFCC 2014. 
Industrial Biotechnology – Multidisciplinary science 
Biological Chemistry 
Bioprocess Engineering 
Molecular Biology 
Systems Biology 
Cell Biology 
Synthetic Biology 
Bio- prospecting
Copyright © NNFCC 2014. 
Create communities and foster stakeholder engagement resulting in collaboration
Copyright © NNFCC 2014. 
£2-5M 
£5M 
£10M 
Early Stage 
Late Stage 
£250K 
£1m 
IB Catalyst Funding streams 
Proof of concept studies
Copyright © NNFCC 2014. 
IB Catalyst Round 1 
31% 
17% 
30% 
22% 
23 
FUNDED 
PROJECTS 
19% 
12% 
41% 
28% 
Fine & Specialities 
Commodities 
Peptides & Proteins 
Efficiency 
TOTAL 
GRANT VALUE 
£21.5M 
Total Project Value = £26.7M
Copyright © NNFCC 2014. 
The EU contributes €1 billion to the research and innovation program, European industries have committed to another €2.7 billion 
Bio-based Industries Public Private Partnership 
http://biconsortium.eu/
Copyright © NNFCC 2014. 
UK process development support
Copyright © NNFCC 2014. 
Making the most of Europe
Copyright © NNFCC 2014. 
The cellulosic ethanol rush 
POET-DSM, US, Operational. Capacity 20M gal (~60,000t/y) 
Beta Renewables, Italy, Operational. Capacity 40,000t/y 
Abengoa, US, Operational. Capacity 25M US gal 
DuPont, US, under construction. Capacity 30M US gal (~90,000t/y) 
GranBio, Brazil, Operational. Capacity 21.6M US gal
Copyright © NNFCC 2014. 
Image courtesy of Abengoa 
Anaerobic digestion – an integral part of cellulosic ethanol biorefineries
Copyright © NNFCC 2014. 
Image courtesy of Poet/DSM 
Biorefineries create integration potential
Copyright © NNFCC 2014. 
The Graduate (1967)
Copyright © NNFCC 2014. 
In 2011 Coca Cola distributed 
5bn plant bottle packages across 20 countries 
Image courtesy of Coca Cola
Copyright © NNFCC 2014. 
“The global bio based succinic acid market is expected to reach market volume of 710.0 kilo tons by 2020, growing at a CAGR of 45.6% during 2013- 2020” - Allied Market Research 
Operating a 13,600t/a nameplate capacity plant in Louisiana, US 
Constructing a 30,000t/a nameplate capacity plant in Ontario, Canada 
Operating a 10,000 t/a nameplate capacity plant in Cassano Spinola, Italy 
Operating a 10,000 t/a nameplate capacity plant in Montmeló, Spain
Copyright © NNFCC 2014. 
31% 
24% 
23% 
23% 
19% 
19% 
14% 
14% 
9% 
Already using some renewable feedstocks… 
Strategic commitment to use of… 
Currently investing in research &… 
Actively investigating & planning 
Currently partnering with other companies 
Considering 
Strategic interest to back-integrate &… 
Little interest at this time 
Currently investing in renewables-based… 
ICIS chemical business reader survey on sustainability 
Based on responses of 960 participants
Copyright © NNFCC 2014. 
High value products with extended value chains 
Source: European Bioplastics
Copyright © NNFCC 2014. 
The bioeconomy will take time to develop 
It’s not necessarily what you can see that’s important!
Copyright © NNFCC 2014. 
Final thought 
Ensure your terminology is understood by your audience!
Celebrating 10 years of Bioeconomy development 
NNFCC is a UK based consultancy with expertise on the conversion of biomass to bioenergy, biofuels and biobased products. 
We help industry solve complex business challenges and provide vital evidence for policy makers. 
| | www.nnfcc.com | enquiries@nnfcc.co.uk

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The UK development of industrial biotechnology and bioenergy in the context of the global bioeconomy

  • 1. The UK development of Industrial Biotechnology and Bioenergy in the context of the global Bioeconomy
  • 2. Copyright © NNFCC 2014. the set of economic activities relating to the invention, development, production and use of biological products and processes. improve health outcomes, boost the productivity of agriculture and industrial processes, and enhance environmental sustainability. Source - OECD Biological Tools Biological Raw Materials The Bioeconomy Biobased Biotech
  • 3. Copyright © NNFCC 2014. The value of biomass Biomass Functional content Carbon content Energy content Materials Chemicals Liquid & Gaseous Fuels Heat & Power Biorefinery operation Stranded assets Food, Feed & Medicine Cascading use
  • 4. Copyright © NNFCC 2014. Attractive because it’s inherently circular http://www.wageningenur.nl/en/Expertise-Services/Research-Institutes/food-biobased-research/Expertise-areas/Biorefinery.htm
  • 5. Copyright © NNFCC 2014. A major global employer
  • 6. Copyright © NNFCC 2014. A mechanism to drive sustainable development covering Environmental, Economic and Social policy. Today’s bioeconomy in Europe •is worth an estimated €2 trillion •accounts for 22 million jobs •9% of total employment in the EU Each euro invested in EU-funded bioeconomy research and innovation is estimated to trigger €10 of value added in bioeconomy sectors by 2025. EUROPEAN BIOECONOMY Innovating for Sustainable Growth A Bioeconomy for Europe February 2012
  • 7. Copyright © NNFCC 2014. Bio-based value propositions •New or enhanced product performance (in use phase or wider life cycle) •Lower cost production routes •Consumer desire for environmentally friendly products •Value created through policy intervention
  • 8. Copyright © NNFCC 2014. Cost to develop and win marketing approval for a new drug is $2.6 billion 1 1) Source: Tufts CSDD http://www.firstwordpharma.com/node/1246255#axzz3KByBqK7a Clear functional value in biopharma
  • 9. Copyright © NNFCC 2014. Emotional value
  • 10. Copyright © NNFCC 2014. Changing monetary cost base 0 50 100 150 200 250 300 Commodity Agricultural Raw Materials Commodity Food Crude Oil
  • 11. Copyright © NNFCC 2014. Source: World Meteorological Organisation Policy intervention
  • 12. Copyright © NNFCC 2014. Innovation Research Development Pilot Demonstration Commercialisation Technology Valley Commercialisation Valley Knowledge ≠ Invention ≠ Innovation
  • 13. Copyright © NNFCC 2014. VISION UK bioscience research delivering products & processes key to the bioeconomy and driving economic growth for the UK and worldwide
  • 14. Copyright © NNFCC 2014. Industrial Biotechnology – Multidisciplinary science Biological Chemistry Bioprocess Engineering Molecular Biology Systems Biology Cell Biology Synthetic Biology Bio- prospecting
  • 15. Copyright © NNFCC 2014. Create communities and foster stakeholder engagement resulting in collaboration
  • 16. Copyright © NNFCC 2014. £2-5M £5M £10M Early Stage Late Stage £250K £1m IB Catalyst Funding streams Proof of concept studies
  • 17. Copyright © NNFCC 2014. IB Catalyst Round 1 31% 17% 30% 22% 23 FUNDED PROJECTS 19% 12% 41% 28% Fine & Specialities Commodities Peptides & Proteins Efficiency TOTAL GRANT VALUE £21.5M Total Project Value = £26.7M
  • 18. Copyright © NNFCC 2014. The EU contributes €1 billion to the research and innovation program, European industries have committed to another €2.7 billion Bio-based Industries Public Private Partnership http://biconsortium.eu/
  • 19. Copyright © NNFCC 2014. UK process development support
  • 20. Copyright © NNFCC 2014. Making the most of Europe
  • 21. Copyright © NNFCC 2014. The cellulosic ethanol rush POET-DSM, US, Operational. Capacity 20M gal (~60,000t/y) Beta Renewables, Italy, Operational. Capacity 40,000t/y Abengoa, US, Operational. Capacity 25M US gal DuPont, US, under construction. Capacity 30M US gal (~90,000t/y) GranBio, Brazil, Operational. Capacity 21.6M US gal
  • 22. Copyright © NNFCC 2014. Image courtesy of Abengoa Anaerobic digestion – an integral part of cellulosic ethanol biorefineries
  • 23. Copyright © NNFCC 2014. Image courtesy of Poet/DSM Biorefineries create integration potential
  • 24. Copyright © NNFCC 2014. The Graduate (1967)
  • 25. Copyright © NNFCC 2014. In 2011 Coca Cola distributed 5bn plant bottle packages across 20 countries Image courtesy of Coca Cola
  • 26. Copyright © NNFCC 2014. “The global bio based succinic acid market is expected to reach market volume of 710.0 kilo tons by 2020, growing at a CAGR of 45.6% during 2013- 2020” - Allied Market Research Operating a 13,600t/a nameplate capacity plant in Louisiana, US Constructing a 30,000t/a nameplate capacity plant in Ontario, Canada Operating a 10,000 t/a nameplate capacity plant in Cassano Spinola, Italy Operating a 10,000 t/a nameplate capacity plant in Montmeló, Spain
  • 27. Copyright © NNFCC 2014. 31% 24% 23% 23% 19% 19% 14% 14% 9% Already using some renewable feedstocks… Strategic commitment to use of… Currently investing in research &… Actively investigating & planning Currently partnering with other companies Considering Strategic interest to back-integrate &… Little interest at this time Currently investing in renewables-based… ICIS chemical business reader survey on sustainability Based on responses of 960 participants
  • 28. Copyright © NNFCC 2014. High value products with extended value chains Source: European Bioplastics
  • 29. Copyright © NNFCC 2014. The bioeconomy will take time to develop It’s not necessarily what you can see that’s important!
  • 30. Copyright © NNFCC 2014. Final thought Ensure your terminology is understood by your audience!
  • 31. Celebrating 10 years of Bioeconomy development NNFCC is a UK based consultancy with expertise on the conversion of biomass to bioenergy, biofuels and biobased products. We help industry solve complex business challenges and provide vital evidence for policy makers. | | www.nnfcc.com | enquiries@nnfcc.co.uk