2. Introduction
Linear hemosiderin in the leptomeninges and
the superficial layers of the cerebral and
cerebellar cortices, the brainstem and the
spinal cord
Fearnley JM, Stevens JM, Rudge P. Superficial siderosis of the central nervous system. Brain. 1995;118:1051–66.
Charidimou A, Linn J, Vernooij MW, Opherk C, Akoudad S, Baron JC, Greenberg SM, Jäger HR, Werring DJ. Cortical superficial siderosis: detection and clinical significance in cerebral amyloid
angiopathy and related conditions. Brain. 2015;138:2126–39.
Koeppen AH, Dentinger MP. Brain hemosiderin and superficial siderosis of the central nervous system. J Neuropathol Exp Neurol. 1988;47:249–70.
3. Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis: Etiology, Neuroradiological
Features and Clinical Findings. Clinical Neuroradiology. 2022 Nov 28:1-4.
5. Cortical Superficial Siderosis
Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis: Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology. 2022 Nov 28:1-4.
6. Mimics of cortical superficial
siderosis
Cortical vein thrombosis
Cortical hemorrhagic transformation in
cerebral infarcts
Laminar cortical necrosis (e.g. hypoxic injury,
status epilepticus)
Sturge Weber syndrome
Calcifying angiopathy/mineralizing
microangiopathy
Cockayne syndrome
Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis: Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology. 2022 Nov 28:1-4.
7. Summary
Linear hemosiderin in the leptomeninges and
the superficial layers of the cerebral and
cerebellar cortices, the brainstem and the
spinal cord
Supratentorial vs infratentorial
Various etiology
MRI brain
Treatment based on etiology