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CAUSES OF MENTAL DISORDERS 
By Clinical Officer NIYOMURENGEZI 
Abenezel
amurengezi@gmail.com
Definition of Mental disorders 
Mental disorder/ illness is a disorder/illness that 
causes disturbances in thinking, perception 
and behavior beyond those that might be 
experienced even in accurately distressed 
state( Dogra, N.;Lunn, B.;Copper, S. 2011).
Causes of Mental disorders 
It is unusual in psychiatry to find many disorders 
that have a single etiological factor. 
Mental health problems/disorders usually arise 
out of complex interplay between the 
biological, the social and the psychological 
factors.
Causes of Mental disorders 
Key etiological factors predisposing, precipitating 
and/ or perpetuating to mental disorders are 
arranged as following: 
Biological factors: 
Physical disorders 
Genetic factors 
Changes in brain structure, neuropharmacology 
and functional imaging.
Physical factors 
• Physical factors 
 In utero and birth 
problems: 
 Intra uterine exposure to 
toxin 
 Perinatal,brain injury at 
birth; premature birth 
 Severe head injury 
• Related disorder or 
features 
 Fetal alcohol syndrome 
ADHD( Attention Deficit 
Hyperactivity Disorder) 
ADHD 
May impair intellectual 
abilities 
Mood disorders 
 Frontal lobe disorder
Physical factors con’t… 
Physical factors 
 Infection 
 Syphilis 
 HIV 
 Viral encephalitis(e.g.HSV) 
 Neurological disorders 
 Neoplasm and other space 
occupying lesions 
• Related disorder or features 
 Dementia 
 Dementia, sce misuse, 
depression 
 Amnesic Sd, behavoral 
disturbances, irritability, 
depression 
 Personality changes 
 Mood disorders
Physical factors con’t… 
Physical factors 
Neurological disorders 
 Poorly controlled 
temporal lobe epilepsy 
Post myocardial 
infarction 
Endocrine disturbance 
 Hyperthyroidism 
• Related disorder or features 
Schizophrenia-like 
psychosis 
Depression 
Anxiety
Physical factors con’t… 
• Physical factors 
 Hypothyroidism 
 Addison’s disease 
Cerebro-vascular 
 Stroke 
 Arteriovenous 
malformations 
• Related disorder or features 
Depression 
Depression 
Depression, mood 
variability, anxiety, 
change in personality 
Mood disorder or 
anxiety
Physical factors con’t… 
• Physical factors 
Iatrogenic factors 
 Corticosteroids 
 Anabolic steroids 
 Methylphenidate 
• Related disorder or features 
Elation and depression 
Aggression, changes in 
personality 
Psychosis
Changes in brain structure, neuropharmacology 
and functional imaging. 
• Reduced overall brain volume 
• Increased volume of cerebral ventricles 
• Reduction in volume of parts of the frontal 
and temporal cortices
Causes of Mental disorders con’t… 
Psychological factors: 
Individual personality traits and personality 
types are significant factors the development 
of mental health problems. This encompasses 
temperament type, which is often used for 
children. The development life stage that 
someone is at may also be an important 
factor.
Psychological factors 
Personality types 
Attachment 
Self-esteem 
Intellectual Quotient ( IQ)
Causes of Mental disorders con’t… 
Social factors: 
Cultural factors 
Religion 
Families 
Neighborhoods and housing 
Work and school 
 Life events ( which are not a normal expected 
part of life). 
Environment factors
Causes of Mental disorders con’t… 
Socio-political factors: 
Socioeconomic disadvantage 
War and conflict 
Stress 
Resilience
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GENERAL CAUSES OF MENTAL DISORDERS

  • 1. CAUSES OF MENTAL DISORDERS By Clinical Officer NIYOMURENGEZI Abenezel
  • 3. Definition of Mental disorders Mental disorder/ illness is a disorder/illness that causes disturbances in thinking, perception and behavior beyond those that might be experienced even in accurately distressed state( Dogra, N.;Lunn, B.;Copper, S. 2011).
  • 4. Causes of Mental disorders It is unusual in psychiatry to find many disorders that have a single etiological factor. Mental health problems/disorders usually arise out of complex interplay between the biological, the social and the psychological factors.
  • 5. Causes of Mental disorders Key etiological factors predisposing, precipitating and/ or perpetuating to mental disorders are arranged as following: Biological factors: Physical disorders Genetic factors Changes in brain structure, neuropharmacology and functional imaging.
  • 6. Physical factors • Physical factors  In utero and birth problems:  Intra uterine exposure to toxin  Perinatal,brain injury at birth; premature birth  Severe head injury • Related disorder or features  Fetal alcohol syndrome ADHD( Attention Deficit Hyperactivity Disorder) ADHD May impair intellectual abilities Mood disorders  Frontal lobe disorder
  • 7. Physical factors con’t… Physical factors  Infection  Syphilis  HIV  Viral encephalitis(e.g.HSV)  Neurological disorders  Neoplasm and other space occupying lesions • Related disorder or features  Dementia  Dementia, sce misuse, depression  Amnesic Sd, behavoral disturbances, irritability, depression  Personality changes  Mood disorders
  • 8. Physical factors con’t… Physical factors Neurological disorders  Poorly controlled temporal lobe epilepsy Post myocardial infarction Endocrine disturbance  Hyperthyroidism • Related disorder or features Schizophrenia-like psychosis Depression Anxiety
  • 9. Physical factors con’t… • Physical factors  Hypothyroidism  Addison’s disease Cerebro-vascular  Stroke  Arteriovenous malformations • Related disorder or features Depression Depression Depression, mood variability, anxiety, change in personality Mood disorder or anxiety
  • 10. Physical factors con’t… • Physical factors Iatrogenic factors  Corticosteroids  Anabolic steroids  Methylphenidate • Related disorder or features Elation and depression Aggression, changes in personality Psychosis
  • 11. Changes in brain structure, neuropharmacology and functional imaging. • Reduced overall brain volume • Increased volume of cerebral ventricles • Reduction in volume of parts of the frontal and temporal cortices
  • 12. Causes of Mental disorders con’t… Psychological factors: Individual personality traits and personality types are significant factors the development of mental health problems. This encompasses temperament type, which is often used for children. The development life stage that someone is at may also be an important factor.
  • 13. Psychological factors Personality types Attachment Self-esteem Intellectual Quotient ( IQ)
  • 14. Causes of Mental disorders con’t… Social factors: Cultural factors Religion Families Neighborhoods and housing Work and school  Life events ( which are not a normal expected part of life). Environment factors
  • 15. Causes of Mental disorders con’t… Socio-political factors: Socioeconomic disadvantage War and conflict Stress Resilience
  • 16. +250784521673 • Do you have a question????????? • Thank you so much