Legg Calve Perthes disease is avascular necrosis of the femoral head in children, most commonly affecting boys ages 4-8. It has an unknown cause but may be associated with conditions like ADHD. Presentation includes a limp or hip/thigh pain. X-rays show changes in the femoral head over time. Treatment depends on age and classification, ranging from observation to osteotomies, with the goal of containing the femoral head to prevent deformity and future arthritis. Prognosis is worse with older age at onset and decreased hip range of motion. Complications can include femoral head deformity, collapse, and leg length discrepancy.
2. Learning Objectives:
Normal anatomy of hip joint.
Introduction and epidemiology
Aetiology and classifications
Clinical presentation
Investigations
Treatment and prognosis
Complications
7. 3-Age
4-8 years is most common age of presentation
4-Population:
more commonly seen in urban populations versus rural
5-Location:
bilateral in 12% ( never at the same stage of disease)
8. the exact cause of disruption of blood supply remains
unknown.
Etiology:
Associated conditions:
-ADHD (33%)
-delayed bone age (98%)
-Thrombophilia (50%)
10. Risk Factors:
1-positive family history
2-low birth weight
3-abnormal birth presentation
4-children exposed to second hand
smoke
5-Asian, Inuit, and Central European
decent
15. Salter-Thompson classification
Based on radiographic cresent sign
crescent sign involves < 1/2 of
femoral head
crescent sign involves > 1/2 of
femoral head
Class A
Class B
16. Stulberg classification
normal
Spherical head
with enlargement,
short neck, or
steep acetabulum
Nonspherical
head
Flat head Flat head with
incongruent hip joint
Gold standard for rating residual femoral head deformity and joint
congruence
17. Clinical presentation:
-insidious onset
-may cause
painless limp
-intermittent
knee, hip, groin
or thigh pain
Physical Exam:
Symptoms:
-Trendelenburg gait
-antalgic limp
limb length
discrepancy is a late
finding
-hip stiffness with loss
of internal rotation
and abduction
-gait disturbance:
18. Investigations:
Plain radiographs:
AP of pelvis and frog leg laterals
early findings include:
medial joint space widening (earliest)
irregularity of femoral head ossification
cresent sign (represents a subchondral fracture)
19. MRI
can provide early diagnosis revealing alterations in the
capital femoral epiphysis and physis.
Bone scan:
can confirm suspected case of LCP
decreased uptake (cold lesion) can predate changes on radiographs
Arthrogram
a dynamic arthrogram can demonstrate coverage and containment
of the femoral head
21. Treatment:
The main Goals of treatment:
1-keep the femoral head contained and
maintain good motion
2-containment limits deformity and minimizes loss
of sphericity and lessen subsequent
degenerative changes.
22. Non-operative:
observation alone, activity restriction, and physical therapy
Indications:
1-children < 8 years of age
2-children with lateral pillar A
3-consider activity restriction and protected weight-bearing
during earlier stages until reossification is complete
24. Operative:
Femoral or pelvic osteotomy
Indications:
1-children > 8 years of age, especially lateral pillar B and B/C
improved outcomes with surgery for lateral pillar B and B/C in
children > 8 years
poor outcome for lateral pillar C regardless of treatment.
27. Prognosis:
prognosis worse with:
1-age (bone age) > 6 years at presentation
2-female sex
3-decreased hip range of motion (abduction)
prognosis improved with:
1-age (bone age) < 6 years at presentation
28. Complications:
The head of the femur may lose its normal, spherical
shape and/or collapse.
Also, degenerative joint disease can occur (i.e. as
occurs in osteoarthritis).
The affected leg may lose some of its motion and may
become shorter than the normal leg.