This document discusses evidence-based practice (EBP) in nursing. It defines research utilization (RU) as using study findings in practice, while EBP bases clinical decisions on the best available evidence, especially high-quality research. Resources for EBP include systematic reviews, clinical guidelines, and preappraised evidence. Barriers to using research in nursing include research-related issues, nurse-related factors, organizational barriers, and issues related to the nursing profession. Individual EBP involves framing a question, searching evidence, appraising evidence, integrating evidence with other factors, and assessing effectiveness.