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Meet Management
Conference
New York, June 5, 2014
Marijn Dekkers, CEO Bayer
Disclaimer
This presentation may contain forward-looking statements based on current
assumptions and forecasts made by Bayer Group or subgroup management.
Various known and unknown risks, uncertainties and other factors could lead to
material differences between the actual future results, financial situation,
development or performance of the company and the estimates given here.
These factors include those discussed in Bayer’s public reports which are
available on the Bayer website at www.bayer.com.
The company assumes no liability whatsoever to update these forward-looking
statements or to conform them to future events or developments.
• Bayer Investor Presentation • Meet Management • June 2014Page 2
Page 1
Our Mission –
Innovation and Customer Value
 Bayer is an innovation company
 With a strong “innovation portfolio”
 Addressing new growth areas
 Capable of identifying and using
breakthrough innovations
 Bayer is innovative in many ways:
Products, technologies, processes,
business models, strategies
 Bayer products improve
the quality of people’s lives
 Bayer has an excellent understanding
of human, animal and plant health,
as well as of high-quality materials
 Respect for people and nature
is an essential part of our values
Science / Innovation Better Life
Science For A Better Life
• Bayer Investor Presentation • Meet Management • June 2014
Page 2
Our Business Portfolio –
Leading in Its Markets
Break-down excluding reconciliation
Sales 2013: €40.2bn
CropScience
Chemical crop protection & biologicals
global #2, seeds & traits
€8.8bn
MaterialScience
Polyurethanes and polycarbonates,
global #1/2
€11.2bn
HealthCare
Pharmaceuticals €11.2bn,
leading positions in core indications
Consumer Health €7.7bn,
OTC #2, blood glucose meters #3, Animal
Health #5, contrast media #1
€18.9bn
23%
29%
48%
• Bayer Investor Presentation • Meet Management • June 2014
We Generate Almost 90 Percent of our
Earnings in the Life Sciences Businesses
Page 3
*EBITDA before special items
23%
29%
45%
88% 12%
Sales 2013 Adj. EBITDA 2013*
Human
Health
3%
Breakdown excluding Reconciliation
Material
Science
Plant Health
Animal
Health
Life
Sciences
Material
Science
• Bayer Investor Presentation • Meet Management • June 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 4
2010-2013 –
A Period of Significant Success
 Delivered growth and performance
 Unprecedented R&D productivity
 Pharma launch product sales ahead of expectations
 Executing successfully our OTC growth strategy
 CropScience customer-centric strategy bearing fruit
 Capital discipline at MaterialScience
2010-2013 – A Period of Significant Progress
Page 5
2010 2011 2012 2013
35.1
36.5
39.7 40.2
7.1
7.6
8.3 8.4
Sales 5%
Core EPS 10%
Adj. EBITDA 6%
4.19
4.83
5.30
5.61
Sales and adjusted EBITDA in € billion, core EPS in €
CAGR 2010-2013
• Bayer Investor Presentation • Meet Management • June 2014
Page 6
EBIT
in € million
+18%
2,096
1,771
Sales
in € million
% currency & portfolio adj.
+8%
10,55510,266
EBITDA
adjusted*
in € million
+12%
2,738
2,453
Core EPS
in €
+15%
1.95
1.70
*before special items
Q1’14Q1’13 Q1’14Q1’13 Q1’14Q1’13 Q1’14Q1’13
Strong Momentum Continued in Q1 2014
Despite Significant Currency Headwind
• Bayer Investor Presentation • Meet Management • June 2014
FY 2014 Group Guidance Maintained –
Targeting Further Sales and Earnings Growth
Page 7
2013 2014E*
Sales €40.2bn
~5% to
~€41-42bn
(neg. FX effect approx. -2%)
adj. EBITDA €8.4bn
low- to mid-single-
digit % increase
(neg. FX effect approx. -5%)
core EPS €5.61
mid-single-digit %
increase
(neg. FX effect approx. -6%)
Sales ∆ Fx and portfolio adjusted, EBITDA before special items
*Assuming average Fx rates of Q4’13 (USD 1.36)
Outlook depends on specific planning assumptions as detailed in the Annual Report• Bayer Investor Presentation • Meet Management • June 2014
Page 8
2013 Sales CAGR 2016e
Pharma: Maximize Value of
Launch Products
• Bayer Investor Presentation • Meet Management • June 2014
24 Successful Phase III Clinical Trials
at Pharma since 2010
Page 9
 Various indications incl. treatment of deep vein thrombosis/pulmonary
embolism, stroke prevention in atrial fibrillation and secondary prevention
of acute coronary syndrome
 Wet age-related macular degeneration, diabetic macular edema, myopic
choroidal neovascularization and central retinal vein occlusion
 Metastatic colorectal cancer and metastatic gastrointestinal stromal tumors
 Metastatic castration-resistant prostate cancer with symptomatic bone
metastases
 Pulmonary arterial hypertension and chronic thromboembolic
pulmonary hypertension
 Radioactive iodine refractory differentiated thyroid cancer
 Prophylaxis in hemophilia A: Site-specific PEGylated Factor VIII with
5- or 7-days dosing intervals
• Bayer Investor Presentation • Meet Management • June 2014
BAY 94-9027
Major examples
Launch Products Drive Growth at Pharma
• Bayer Investor Presentation • Meet Management • June 2014Page 10
Sales in € billion; ∆% Fx & portf. adjusted
Pharma Sales / Launch Products Launch Products 2013
2010 2011 2012 2013
10.0 1.5
25%
949
197
333
3
41
Sales in € million
9.9
10.8
11.2
+1%
+4%
+9%
Launch Products Expected to Contribute
~€2.8bn to Pharma Sales in 2014
• Bayer Investor Presentation • Meet Management • June 2014
 Executing >100 launch events* in
2014
 Continuous R&D investments in
life-cycle management
 Increased marketing and sales
investments in emerging markets
 Incremental marketing and R&D
investments of €0.5bn in 2014e
* new indications and new countries
Page 11
Page 12
Pharma – Peak Sales Potential of Launch
Products was Raised in February to ≥€7.5bn
 Continued successful launch exe-
cution and life cycle management
 Unchanged
 Unchanged
 Unchanged
~€3.5bn
≥€1.5bn
≥€1bn
≥€1bn
≥€0.5bn
>€2bn
≥€1bn
Old Current
• Bayer Investor Presentation • Meet Management • June 2014
 Continued successful launch exe-
cution and life cycle management
Two Recent Steps Forward for Bayer’s
Pharma Business
• Bayer Investor Presentation • Meet Management • June 2014
Acquisition of
Algeta
Strategic Pharma
sGC Collaboration
with Merck
 Full control over Xofigo
 Comprehensive life-cycle management program,
including studies in earlier settings of prostate
cancer, combination studies and other tumors
 Complementing Bayer’s sGC franchise, including
Adempas, with Merck’s cardiovascular capabilities
 Leverage joint development capability to fully explore
broad potential of sGCs
 Building Bayer’s US presence in specialty pharma
while leveraging Merck’s US strength
Page 13
Pharma – Maximizing
the Value of Launch Products
Page 14
2013
Guidance
2014
Aspiration
2016
Sales Increase €11.2bn High-single digit %
(neg. FX effect approx. -2%)
8% CAGR
Adj. EBITDA Increase €3.5bn Low- to mid-single digit %
(neg. FX effect approx. -€150m)
Adj. EBITDA Margin 31.2% Level with prior year ≥33%
Assuming average FX rates of Q4‘13 (USD 1.36)
Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales
• Bayer Investor Presentation • Meet Management • June 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 15
Aspire to Become the Leading
OTC Company
• Bayer Investor Presentation • Meet Management • June 2014Page 16
 Portfolio of some of the world’s most
recognized brands
 Outperforming market growth in past
7 out of 8 years
 Successful expansion in EM focus
markets, China, Brazil, and Russia
 Selected bolt-on acquisitions in key
countries: Steigerwald, Germany &
Dihon, China
 Acquisition of Merck’s Consumer
Care business – a major step
towards OTC leadership
3.4
3.5
3.9 3.9
2010 2011 2012 2013
+5%
+7%
+6%
Consumer Care sales in € billion; ∆% Fx & portfolio adj.
*planned acquisition, closing expected in H2 2014
Successfully Executing OTC Growth Strategy
• Bayer Investor Presentation • Meet Management • June 2014Page 17
Acquisition of Merck’s Consumer Care
Business Makes us #2 Globally and #1 in US
Highlights
$14.2bn investment, all cash, fully
debt financed
Complementary portfolio offering scale
in key categories and optimized
geographic footprint
Full trademark ownership for Claritin
Market Positioning 2013*
*Pro-forma OTC sales 2013; after allowing for the Novartis/Glaxo deal and Bayer/Merck transaction;
CC: Consumer Care
in € billion
Combination Offers Significant Synergy
Potential
• Bayer Investor Presentation • Meet Management • June 2014Page 18
Cost synergies of ~$200m p.a. by 2017
Tax benefits from year 1
 Asset purchase with significant future tax savings
 Savings in marketing costs
 Savings in COGS, administration
Step-up of EBITDA margin pre-special items at Consumer Care
by ~1pp and core EPS accretion of 2% already in the first year
Revenue synergies of already ~$400m by 2017
 Incremental US sales
 Realize brand penetration opportunities ex-US
Revenue
Cost
Tax
Page 19 • Bayer Investor Presentation • Meet Management • June 2014
2013 Sales CAGR 2016e
CropScience: Further Growth at
Benchmark Profitability
Delivering Growth And Performance at
CropScience
6.8
7.3
8.4
8.8
2010 2011 2012 2013
 2013 – the 3rd year in a row
delivering strong sales growth at
record margin
 New product sales 2013 up 33% at
€1.5bn*
 Strong start to 2014 season with
sales up 12%
Sales in € billion, ∆% Fx & portf. adjusted,
Adj. EBITDA margin in %
19.0
24.2
25.5
22.8
+9%
+12%
Page 20 • Bayer Investor Presentation • Meet Management • June 2014
Customer-centric strategy
bearing fruit
*Sales with Crop Protection products launched since 2006
+9%
Significant Contribution from New Crop
Protection Products
• Bayer Investor Presentation • Meet Management • June 2014Page 21
*Sales with Crop Protection products launched since 2006
1.1
1.5
1.8
2.6
2012 2013 2014e 2016e
+33%
Sales from new Crop Protection products
launched since 2006 in €bn
∆% y-o-y, () Fx adj.
Q1
0.6
 (+16%) - Superior ‘all-in-one’
cereal fungicide with yield-boosting
effect
 herbicide (+14%) -
Excellent weed control in corn and
cereals, also in case of glyphosate
resistance
 (+75%) - Broad-spectrum
insecticide with fast, long-lasting
action
 (+112%) - New fungicide now
available in several key markets
Q1 2014 Highlights
Significant Investments in our
Growth Platforms
• Bayer Investor Presentation • Meet Management • June 2014Page 22
BiologicalsSeeds
 >€300m R&D investments p.a. to
support leadership positions in cotton
& oilseed and to develop position in
soybean and wheat
 Further selected acquisitions to
strengthen portfolio and regional
setup, esp. in Latin America
 Launch of first soybean brand
Credenz (2014e)
 Launch of first wheat variety
(2015e)
 Successful market entry with nematode
seed treatment Poncho/Votivo
(sales 2013: ~€150m)
 Acquisition of AgraQuest, global provider
of innovative biological pest management
solutions
 Acquisition of Prophyta, a provider of
well-established products, e.g. nematicide
BioAct
 Acquisition of Biagro* adds nitrogen
inoculants & plant health promoters
*Subject to regulatory approvals
CropScience – Above Market Growth at
Benchmark Profitability
Page 23
2013
Guidance
2014
Aspiration
2016
Sales Increase €8.8bn Mid- to high-single-digit %
(neg. FX effect approx. -3%)
6% CAGR
Adj. EBITDA Increase €2.2bn Low-single-digit %
(neg. FX effect approx. -€150m)
Adj. EBITDA Margin 25.5% - 24-25%
Assuming average FX rates of Q4‘13 (USD 1.36)
Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales
• Bayer Investor Presentation • Meet Management • June 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 24
MaterialScience: Improve
Returns
• Bayer Investor Presentation • Meet Management • June 2014Page 25
Macro-Economic Environment for
MaterialScience Likely to Improve
 Oil price expected to stabilize in
2014 (budget of Ø $110 per bbl*)
 Supply & demand balances of key
products improving with:
 Long-term demand drivers
intact
 Limited net new capacity to
come on stream
21%
18%
27%
19%
Automotive
(+4%)
Electro /
Electronic
(+6%)
Construction
(+4%)
Furniture
(+4%)
Others
(incl.
Chemicals)
15%
Sales by industry 2013 and expected 2014 growth
Key Customer Industries Outlook Additional Key Performance Drivers
*Ø 2013: $110 per bbl
• Bayer Investor Presentation • Meet Management • June 2014Page 26
Q1 2014 – MaterialScience:
Demand Led Growth
Sales Earnings
**CAS: Coatings, Adhesives, Specialties;
*** IO: Industrial Operations
CAS**
0% (+7%)
In € million, ∆% yoy, () = Fx & portf. adjusted
*before special items;
MaterialScience €2,803m; +1% (+5%)
Price
-3%
Volume
+8%
Fx
-3%
Portfolio
-1%
1,510659
IO***
-6% (-5%)
Q1‘13 Q1‘14 Q1‘13 Q1‘14
Adj.
EBITDA*
Adj.
EBIT*
204
366 +79%
43
221
469
165
Polyurethanes
+3% (+6%)
Polycarbonates
-1% (+2%)
>100%
MaterialScience – Asset Utilization and
Efficiency Measures to Drive Cash Returns
• Bayer Investor Presentation • Meet Management • June 2014Page 27
2013
Guidance
2014
Aspiration
2016
Sales Increase €11.2bn Mid-single-digit %
(neg. FX effect approx. -2%)
Volume growth
> global GDP
Adj. EBITDA Increase €1.1bn Increase
(neg. FX effect approx. -€50m)
-
CFROI vs. WACC 5.5% < 6.9% - CFROI > WACC
Assuming average FX rates of Q4‘13 (USD 1.36)
Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales
Bayer –
Optimistic About Future Developments
Peak sales potential of new pharma products of ≥€7.5bn
Track record of performance:
Core EPS with 10% CAGR since 2010
Successful start to 2014 – full-year 2014 group guidance
maintained
Page 28
Successfully executing on OTC growth strategy
• Bayer Investor Presentation • Meet Management • June 2014
Page 29
Appendix
• Bayer Investor Presentation • Meet Management • June 2014
EBIT
in € million
+26%
4,934
3,928
Sales
in € million
% currency & portfolio adj.
+5%
40,15739,741
EBITDA
adjusted*
in € million
+1%
8,4018,280
Core EPS
in €
+6%
5.61
5.30
*before special items
FY’13FY’12 FY’13FY’12 FY’13FY’12 FY’13FY’12
FY 2013 – Encouraging Performance
Driven by Life Sciences
Page 30 • Bayer Investor Presentation • Meet Management • June 2014
FY 2013 –
Regional Performance
Page 31
Africa &
Middle East
Eastern
Europe
Emerging Economies
Emerging
Economies¹
+7%
Others²
+10%
USA
+4%
Western Europe
+2%
2013 Group Sales by Region
Group €40,157m; +5%
~5,100
+15%~5,800
+4%
~1,700
-1%~2,500
+7%
1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe
2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand
In € million, ∆% yoy Fx adjusted
38%
10%
31%
21%
Latin
America
Emerging
Asia³
• Bayer Investor Presentation • Meet Management • June 2014
FY 2013 –
HealthCare
Page 32
*before special items
2013 Sales Earnings
Pharma
+4% (+9%)
Consumer
Health
-1% (+3%)
36%
HealthCare €18,924m; +2% (+7%)
11,1887,736
Price
+1%
Volume
+6%
Fx
-6%
Portfolio
+1%
In € million, ∆% yoy, () = Fx & portf. adjusted
FY‘12 FY‘13 FY‘12 FY‘13
3,232
3,490
1,887 1,844
+8%
-2%
5,119
5,334 +4%
1,460 -3%
3,787
3,973 +5%
2,327
1,421
Adj.
EBITDA*
Adj.
EBIT*
2,552 +10%
• Bayer Investor Presentation • Meet Management • June 2014
FY 2013 –
CropScience
Page 33
Crop Protection
+7% (+11%)
Environmental
Science
-4% (+1%)
*before special items
Seeds
+1% (+1%)
2013 Sales Earnings
In € million, ∆% yoy, () = Fx & portf. adjusted
CropScience €8,819m; +5% (+9%)
Price
+3%
Volume
+7%
Fx
-5%
Portfolio
+1%
7,194
FY‘12 FY‘13 FY‘12 FY‘13
2,025
2,248 +11%
1,543
1,801 +17%
Adj.
EBITDA*
Adj.
EBIT*
651
974
• Bayer Investor Presentation • Meet Management • June 2014
FY 2013 –
MaterialScience
Page 34
2013 Sales Earnings
In € million, ∆% yoy, () = Fx & portf. adjusted
MaterialScience €11,238m; -2% (0%)
Price
0%
Volume
+1%
Fx
-2%
Portfolio
0%
6,054
FY‘12 FY‘13 FY‘12 FY‘13
Adj.
EBITDA*
Adj.
EBIT*
1,263
1,072 -15%
613
429 -30%
Polycarbonates
-6% (-5%)
CAS**
-6% (-2%)
2,640
IO***
-4% (-4%)
1,863
681
Polyurethanes
+1% (+4%)
**CAS: Coatings, Adhesives, Specialties;
*** IO: Industrial Operations
*before special items;
• Bayer Investor Presentation • Meet Management • June 2014
FY 2013 –
Cash Flow And Net Debt Development
Page 35
-€0.3bn 6.7
GCF oFCF
5,832
Invest-
ments
2,157 3,014
∆
y-o-y +28% +16%
NCF
5,171
+14% +12%
Dec 31, 2012 Dec 31, 2013
7.0
FY 2013 Cash Flow Net Debt Development
Cash Flow in € million, Net Debt in € billion
• Bayer Investor Presentation • Meet Management • June 2014
On Our Way to OTC Leadership
Investor Handout – Meet Management
Acquisition of Merck & Co.’s
Consumer Care Business
June 2014 – New York
Evolution of Bayer Consumer Care’s
OTC Business
2008
Acquisition of OTC brand
portfolio from Sagmel
(CEE) and Topsun (China)
1999
Aspirin trademark
centenary-worldwide
sales > €500m
1899
ASPIRIN introduced
as an over-the-counter
(OTC) medicine
1994
Consumer Care business group
created by the acquisition of North
American OTC business of Sterling;
Acquisition of the “Bayer Cross”
Trademark in USA
2005
Acquisition of Roche
Consumer Health
2013
Aspirin trademark sales
of >€900m
Acquisition of
Steigerwald (Germany)
Page 37 • Bayer Investor Presentation • Meet Management • June 2014
2014
Proposed acquisition of Merck’s
Consumer Care business (US)
Transaction agreement signed with
Dihon Pharmaceutical Group (China)
• Bayer Investor Presentation • Meet Management • June 2014Page 38
Growth Strategy
 Maximize brand potential
 Global expansion of key brands
 Exploit our innovation pipeline
 Grow in emerging markets
 Increase commercial power
 Bolt-on acquisitions to strengthen
portfolio & regional set-up
3.4
3.5
3.9 3.9
2010 2011 2012 2013
+5%
+7%
+6%
Consumer Care sales in € billion; ∆% Fx & portfolio adj.
Bayer Consumer Care – Outperforming
Markets in Past 7 Out of 8 Years
Merck’s Consumer Care Business Fits
Perfectly With Bayer Consumer Care
• Bayer Investor Presentation • Meet Management • June 2014
Complementary
Portfolio
Building on core
competencies
 Creation of a global leader in OTC
 Gaining scale in key categories CASF1, dermatology,
and gastrointestinal
 Optimizing footprint in North America
 Strong track record of growing OTC brands
 Strong geographical presence to broaden Merck’s
portfolio globally
 Utilizing integration skills from past transactions
Page 39
Acquisition criteria
fulfilled
 Creating leadership positions in important consumer
care categories and geographies
 Increasing consumer care margin2 by ~1pp from year 1
 Immediate core EPS accretion from year 13
1 cold, allergy, sinus, flu; 2 EBITDA pre-special items;
3 transaction incl. sGC collaboration
Page 40 • Bayer Investor Presentation • Meet Management • June 2014
Combined Portfolio Significantly Strengthens
Global Positions
Gastrointestinal
Analgesics3
CASF2
Nutritionals
Dermatology1
Total
Others4
3,904 1,635 5,539
1,110 386
372 803
126 513
439 141
1,023
834
1 including sun care; 2 Cold, Allergy, Sinus, Flu; 3 including Cardio; 4 Foot Health, Women’s Health, Other
1,496
1,023
1,175
834
580
431
#1
#2
#3
#1
#2
Global position*2013 Sales in €m (pro-forma portfolio)
Note: Merck sales converted at average USD rate of 1.33 (FY 2013)
305
*After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx
MerckBayer
Page 41 • Bayer Investor Presentation • Meet Management • June 2014
Combined Portfolio Significantly Strengthens
Geographic Footprint
Note: Merck sales converted at average USD rate of 1.33 (FY 2013)
*After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx
Latin America
Europe
North America
Total
Asia/Pacific
3,904 1,635 5,539
1,117 1,105
1,621 170
389
513
141
777
2,222
1,791
946
580
#1
#1
#5
#2
Global position*2013 Sales in €m (pro-forma portfolio)
191
169
MerckBayer
FY 2013 sales in € million (∆% yoy Fx-adj.)
321
310
232
214**
207
176
158
257
*Total Aspirin includes Aspirin Complex and Aspirin Cardio (Rx)
**Total Alka-Seltzer includes Alka-Seltzer and Alka-Seltzer Plus
916*
= Rx Sales
Page 42 • Bayer Investor Presentation • Meet Management • June 2014
Combined Top 10 Portfolio –
Individual Brands with Annual Sales >€100m
576
Note: Merck sales converted at average USD rate of 1.33 (FY 2013); based on pro-forma FY 2013 net sales
• Bayer Investor Presentation • Meet Management • June 2014Page 43
Top Priorities To Be Executed Immediately
After Closing of Transaction…
 Ensure fast integration into operations
 Safeguard product supply
 Realize synergy potential
 Prioritize brand strategies within combined portfolio
 Realize Merck brand penetration opportunities ex-US
 Define and execute individual brand strategies
 Develop US scale advantage
 Strive for leadership with trade customers
 Provide a broader product portfolio
Critical mass
in US
Brand Roll-
Out ex-US
Smooth
integration
• Bayer Investor Presentation • Meet Management • June 2014Page 44
Clear Strategy For a Smooth Integration
2014 Q2 2014 Q42014 Q3 2015 (End State)
 Smooth integration expected due to experienced management team
• Ensure effective integration into Consumer Care
• Safeguard on-going product supply
• Prioritize and execute identified brand development / expansion strategies
• Ensure sufficient future capacity for growth
• Capitalize on Merck’s innovation capabilities
• Achieve scale and revenue synergies
• Capture consolidation and efficiency synergies by 2017
 Deal signing  Deal closing  Consolidation / Integration
• Bayer Investor Presentation • Meet Management • June 2014Page 45
Enhanced Scale and Broader Category
Scope Improve Product Offerings
US Retail Sales CASF Benefits from Enhanced Scale
 Co-promoting complementary
brands
 New item assortment and shelving
opportunities
 Improved merchandising efficiencies
 Bigger and more impactful trade
events
 Foster strategic partnerships with
retailers
FY 2013 retail sales in CASF in $ million*
$-
$200
$400
$600
$800
$1,000
$1,200
RB Bayer &
Merck
J&J Merck &
Co.
P&G Pfizer Chattem Bayer GSK
*Source: IRI; Latest 52WK; December 2013
 Make Bayer Consumer Care Top Strategic Partner for US Retailers
Maximizing Brand Potential Through
Global Expansion
Brand Sales by Major Region 2013 Expansion Plans
• Bayer Investor Presentation • Meet Management • June 2014Page 46
Analgesic
~80% in North America
~95% in North America
Wound-healing
~75% in Europe
Anti-fungal
~75% in Europe & LatAm
Vitamins & minerals
~50% in Europe
~80% in North America
CASF
Sun Care
• Bayer Investor Presentation • Meet Management • June 2014Page 47
Russia
Country OTC Market
Sales Growth
2013*
Execution Plans
China
 Global #2
 Growing 2x the
global rate
 Use investments in footprint, brand-building
and sales capabilities to extend Claritin
leadership
 Build sun care category with Coppertone
Brazil
 Global #7
 Fastest growing
market in LATAM
 Use investments in brand-building and
channel capabilities to develop key new
categories (sun care, foot care, allergy)
 Revitalize Coppertone and Dr. Scholl’s
brands
Russia
 Global #4
 Retail OTC is
largest healthcare
segment
 Focus on CASF brands using current
position to roll-out extended offerings
 Achieve #2 position
Execution Plan Focused on Key Brands in
Key Emerging Markets
+38%
+26%
+14%
*Bayer Consumer Care sales, currency-adjusted
Consumer Care is Well-Positioned for
Growth – Aspire to Clear OTC Leadership
OTC Market
Attractive
Bayer Has
Strong #2
Position
Plans for
Continued
Future Growth
 Trends favor continued growth
 OTC market model based on long-term brand building
 OTC businesses becoming more valuable over time
 Leader in key categories
 Multiple strong brands
 Track record of outperforming market growth
 Globalize established brands & launch innovation pipeline
 Focus on emerging markets where most of growth will come
 Strategic acquisitions and alliances
Page 48 • Bayer Investor Presentation • Meet Management • June 2014
Investor Handout – Meet Management
Bayer HealthCare
June 2014 – New York
Leading Positions in Key Healthcare
Markets
• Bayer Investor Presentation • Meet Management • June 2014
Pharma
€11,188m
 Leading positions in key therapeutic categories
Consumer Care
€3,904m
 Global #2 in OTC-pharmaceuticals
Medical Care
€2,526m
 #1 in fluid injection systems, #1 in contrast media,
#3 in blood glucose meters
Animal Health
€1,306m
 Global #5, #2 in parasiticides
Sales Split by Segment 2013
25%
59%
7%
21%
13%
HealthCare €18,924m
Page 50
FY 2013 –
Growth Mainly Pharma Driven
• Bayer Investor Presentation • Meet Management • June 2014
*before special items
FY 2013 HealthCare Sales Earnings
Pharma
+4% (+9%)
Consumer
Health
-1% (+3%)
36%
11,1887,736
In € million, ∆% yoy, () = Fx & portf. adjusted
FY 12 FY 13 FY 12 FY 13
3,232
3,490
1,887 1,844
+8%
-2%
5,119
5,334 +4%
1,460 -3%
3,787
3,973 +5%
2,327
1,421
Adj.
EBITDA*
Adj.
EBIT*
2,552 +10%
HealthCare €18,924m; +2% (+7%)
Price
+1%
Volume
+6%
Fx
-6%
Portfolio
+1%
Page 51
FY 2013 –
Top 10 HealthCare Product Performance
• Bayer Investor Presentation • Meet Management • June 2014
MI: Myocardial infarction
Sales in € million; ∆% y-o-y Fx adjusted
+6%
-12%
-1%
+3%
+2%
+10%
-1%
+2%
+211%
1,202
1,038
916
771
949
719
853
722
603
487
Hemophilia A
Multiple Sclerosis
Anticoagulation
Contraception
Cancer
Blood Glucose Meter
Contraception
Analgetic & sec.
MI Prevention
Parasiticide
-13%
Hypertension
Page 52
FY 2013 – Strong Business Momentum in
All Regions, Especially Emerging Markets
• Bayer Investor Presentation • Meet Management • June 2014
Emerging Economies
25%
FY 2013 HealthCare Sales
Latin
America
Eastern
Europe
Africa &
Middle East
~2,190
+7%
~1,980
+10%
~1,140
~880
+4%
24%
USA
+5%
30%
33%
13%
Sales in € million; ∆% y-o-y Fx adjusted
Emerging
Economies¹
+8%
Emerging
Asia³
Western
Europe +6%
Others²
+12%
HealthCare €18,924m; +2% (+7%)
Page 53
+10%
1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe
2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand
• Bayer Investor Presentation • Meet Management • June 2014
Recently Launched Pharma
Products Drive Growth
Page 54
Q1 2014 – HealthCare:
Recently Launched Products Drive Growth
Page 55
*before special items
Sales Earnings
Pharma
+9% (+15%)
Consumer
Health
-5% (+1%)
36%
HealthCare €4,572m; +3% (+9%)
2,7821,790
Price
0%
Volume
+9%
Fx
-7%
Portfolio
+1%
In € million, ∆% yoy, () = Fx & portf. adjusted
Q1‘13 Q1‘14 Q1‘13 Q1‘14
832 873
445 428
+5%
-4%
1,277
1,301 +2%
343 -6%
953 946 -1%
610
321
Adj.
EBITDA*
Adj.
EBIT*
625 +2%
• Bayer Investor Presentation • Meet Management • June 2014
Q1 2014 –
Top 10 HealthCare Product Performance
• Bayer Investor Presentation • Meet Management • June 2014
MI: Myocardial infarction
Sales in € million; ∆% y-o-y Fx adjusted
+133%
-6%
+14%
+12%
+239%
-12%
-1%
-22%
342
270
183
178
190
146
181
157
140
Hemophilia A
Multiple Sclerosis
Anticoagulation
Contraception
Cancer
Ophthalmology
Contraception
Analgetic & sec.
MI Prevention
-3%
Hypertension
Page 56
Blood Glucose Meter
217 +6%
• Bayer Investor Presentation • Meet Management • June 2014Page 57
2013 Sales CAGR 2016e
Pharma: Maximize Value of
Launch Products
2011 2012 2013 2014
Page 58
Pharma – Incremental Investments For
A New Performance Level
* new indications and new countries; products include Xarelto, Eylea,
Stivarga, Xofigo, Adempas• Bayer Investor Presentation • Meet Management • June 2014
Launch product sales in € bn
 Launch product* sales target of ~€2.8bn
in 2014 (old aspiration 2015: >€2.5bn)
 Launch phase to continue with >100
new launch events*
 Continuous R&D investments in life-
cycle management
 R&D investments in new drug
candidates
 Increased marketing and sales
investments in emerging markets
 Incremental marketing and R&D
investments of €0.5bn planned in 2014
<0.1
0.4
1.5
~2.8
Stivarga
Xarelto
Eylea
Xofigo
Recently launchd
Pharma products*
Pharma – Additional Investments To
Execute >100 Launch Events in 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 59
1: regulatory process ongloing, launch preparations assuming approval
DTC: Differentiated thyroid cancer; mCRC: Metastatic colorectal cancer ;
mGIST: Metastatic gastrointestinal cancer; ACS: Acute coronary syndrome
 ~ 30 launches planned in secondary prevention of ACS
 Market introduction planned in >20 countries
 > 30 launches planned in mGIST1 in EU and other markets; continue
roll-out in mCRC (examples include Spain, Italy, Turkey)
 ~ 15 launches planned, including wetAMD and additional indications
(CRVO, mCNV1, DME1)
 Launches1 planned in > 20 countries
 > 30 launches planned in DTC1 in EU and other markets
Major Examples
 > 30 launches planned
• Bayer Investor Presentation • Meet Management • June 2014
Peak Sales Potential of Launch
Products Raised in February 2014
Peak Sales Potential*
* from 5 recently launched products: Xarelto, Eylea, Stivarga, Xofigo, Adempas
Page 60
Page 61
Pharma – Peak Sales Potential of Launch
Products Raised in February to ≥ € 7.5bn*
*assuming approvals and launches as planned
 Continued successful launch exe-
cution and life cycle management
 Continued successful launch exe-
cution and life cycle management
 Unchanged
 Unchanged
 Unchanged
~€3.5bn
≥€1.5bn
≥€1bn
≥€1bn
≥€0.5bn
>€2bn
≥€1bn
Old Current
• Bayer Investor Presentation • Meet Management • June 2014
Xarelto – Broadest Profile of Any Novel Oral
Anticoagulant
• Bayer Investor Presentation • Meet Management • June 2014
Peak sales potential ~ €3.5bn
 Oral Factor Xa inhibitor
 Once-daily dosing advantage*
 First launches in EU for secondary
prevention of ACS underway
 Two-dimensional approach in life-cycle
management:
 Expansion into additional
thromboembolic disease areas
 Strengthening the clinical profile in
approved indications and special
patient populations
*exception 15mg BID dosing for treatment of acute DVT/PE or 2.5mg
BID for ACS sec. prevention; ACS: Acute coronary syndromePage 62
• Bayer Investor Presentation • Meet Management • June 2014
Xarelto – Performance Exceeding
Expectations
Page 63
 World-class launch, achieved
leading position in the novel
anticoagulants segment in key
markets
 Uptake significantly exceeding
expectations
 Sales target 2014: € 1.3-1.5bn131
155
219
259
316
342
Q4'12 Q1'13 Q2'13 Q3'13 Q4'13 Q1'14
Xarelto sales in million €
Expanding and Strengthening the Profile
of Xarelto
• Bayer Investor Presentation • Meet Management • June 2014Page 64
 Significant medical need in thromboembolic disease areas
 Heterogeneous patient populations in existing indications deserve further
characterisation
 Two-dimensional approach in life-cycle management
Expansion into addional
thromboembolic disease areas
Strenghtening the clinical profile in
approved indications
 Peripherial arterial disease / coronary
arterial disease
 Chronic heart failure with coronary
arterial disease
 Medically ill patients
 Patients with percutaneus coronary
intervention
 Patients who undergo cardioversion
 Patients undergoing ablation
 Evaluate 10mg /20mg dose vs. ASA in
secondary prevention of VTE
ASA: Acetylsalicylic acid, VTE: Venous thromboembolism
Eylea – Developed for the Treatment of
Multiple Back-of-the-Eye-Diseases
• Bayer Investor Presentation • Meet Management • June 2014
Peak sales potential ≥ €1.5bn
 Eylea is an anti-angiogenic therapy,
formulated for injection into the eye
 Strong adoption by retina community in
wAMD based on convenient bimonthly
dosing1 regimen
 Comprehensive range of indications to
address major eye diseases2:
 Launched in wAMD and CRVO; roll-out
ongoing
 Filed for DME (EU: 11/13; J: 02/14)
 Filed for mCNV in Japan (11/13)
 Filing planned for BRVO (in J, other
regions under evaluation)
1: after an initial phase of 3 consecutive monthly injections; 2: Bayer has marketing rights ex-US; wAMD: Wet age-related macular degeneration; CRVO:
Central retinal vein occlusion; BRVO: Branched retinal vein occlusion; mCNV: Myopic choroidal neovascularization; DME: Diabetic macular edema
Page 65
• Bayer Investor Presentation • Meet Management • June 2014
Eylea – Excellent Launch Trajectory
Page 66
 Excellent launch execution ahead of
expectations
 Market shares* > 45 % in Japan and
Australia
 Roll-out in Europe underway
 Strong uptake in early launch markets
Germany and Switzerland
 Encouraging launch in France and UK
 Positive NICE guidance for CRVO
indication in UK obtained in 02/14
 Progress with launch preparations for
i) additional countries and ii) additional
back-of-the-eye diseases**
*Market share as of December 2013 (Source IMS)
** pending regulatory approval
14
49
73
85
126
157
Q4'12 Q1'13 Q2'13 Q3'13 Q4'13 Q1'14
Eylea sales in million €
Stivarga – Developed as a Treatment for
Cancers of the Digestive Tract
• Bayer Investor Presentation • Meet Management • June 2014
 Oral cancer drug, potently blocking multiple
protein kinases
 Launched for treatment of mCRC and
mGIST in the US & Japan
 Launched for treatment of mCRC (8/13)
and filed for mGIST (9/13) in Europe
 Encouraging initial uptake
 Expanding to new indications
 Phase III in 2nd line liver cancer
ongoing
 Phase III in CRC (adjuvant therapy
after resection of liver metastases)
ongoing
mCRC: Metastatic colorectal cancer
GIST: Gastrointestinal stromal tumors
Peak sales potential ≥ €1bn
Page 67
Entering Additional Cancers of the
Gastro-Intestinal Tract with Stivarga
• Bayer Investor Presentation • Meet Management • June 2014Page 68
 Positive clinical data in metastatic colorectal cancer and 2nd-line
hepatocellular carcinoma
 Mode of action suggesting activity in a broad range of tumor types
 Life-cycle management targets:
 Phase III in 2nd-line hepatocellular
carcinoma
 Phase III in colorectal cancer after
resection of liver metastases
 Signal generating early clinical studies
in various cancer types including
gastric cancer
HCC: Hepatocellular carcinoma
CRC: Colorectal cancer
Expand in HCC and CRC Expand to additional tumor types
• Bayer Investor Presentation • Meet Management • June 2014
Xofigo – A New Treatment for CRPC
Patients with Bone Metastases
 First in class alpha-pharmaceutical
 Treatment of CRPC with symptomatic bone
metastases and no known visceral
metastatic disease
 Launched in the US (06/13)
 Approved in Europe (11/13) – launch
underway
 High awareness among oncologists and
urologists
 Life-cycle program initiated (including
combination studies in earlier settings of
prostate cancer)
CRPC: Castration-resistant prostate cancer
Peak sales potential ≥ €1bn
Page 69
Addressing Multiple Life-Cycle Opportunities
for Xofigo (Radium-223 dichloride)
• Bayer Investor Presentation • Meet Management • June 2014Page 70
Life-Cycle
Opportunities
Repeat dosing in CRPC
Higher dose in CRPC
Earlier disease stages
of CRPC
Combination study in CRPC
Expansion into additional
cancer types
Addressed Through
Phase II trial assessing the short
and long-term safety of re-
treatment
Phase II trial with dose higher
than the approved 50 kBq/kg
Phase I and/or II studies in breast
cancer, osteosarcoma and
potentially in additional cancer
types
Phase III combination trial with
abiraterone / phase II combination
with abiraterone or enzalutamide
CRPC: Castration resistant prostate cancer
Status
initiated
initiated
initiated
planned
Adempas – First-in-Class sGC Stimulator for
Treatment of PAH and CTEPH
• Bayer Investor Presentation • Meet Management • June 2014
 Oral soluble guanylate cyclase (sGC)
stimulator approved for treatment of PAH
and CTEPH
 First and only drug receiving marketing
authorization for the treatment of CTEPH
 Launched in the US for treatment of PAH
and CTEPH (10/13)
 Launched in J for treatment of CTEPH
(04/14) – filed for PAH (04/14)
 Launched in first EU countries for CTEPH
and PAH (04/14)
 Collaboration with Merck & Co. announced
in May 2014 - 50/50 cost/profit split, joint
development and commercialization
strategy
*for indications PAH and CTEPH; CTEPH; : Chronic
thromboembolic pulmonary hypertension; PAH: Pulmonary arterial
hypertension
Peak sales potential ≥ €0.5bn*
Page 71
Adempas – Life Cycle Management Beyond
PAH and CTEPH
• Bayer Investor Presentation • Meet Management • June 2014
PAH: Pulmonary arterial hypertension; CTEPH: Chronic thromboembolic
pulmonary hypertension; PH-ILD: Pulmonary hypertension due to
interstitial lung disease
Page 72
 Positive phase II data in PH-ILD prompt initiation of phase IIb in PH-IIP (a specific sub-
segment of PH-ILD)
 Majority of PH-IIP patients suffer from pulmonary hypertension due to idiopathic
pulmonary fibrosis
 No approved treatment option
 Chronic systemic autoimmune disease characterized by fibrosis
 No approved treatment
 Strong preclinical antifibrotic data
Pulmonary hypertension with idiopathic interstitial pneumonia (PH-IIP)
Diffuse systemic sclerosis (SSc)
Page 73
Accelerating the Development
of 5 early/mid-stage Pipeline
Assets
• Bayer Investor Presentation • Meet Management • June 2014
R&D
Five New Molecular Entities Selected For
Accelerated Development
• Bayer Investor Presentation • Meet Management • June 2014Page 74
Project Mechanism Indication Status
Copanlisib
(BAY 80-6946)
PI3-Kinase
Inhibitor
Cancer
Phase II in NHL
ongoing
Finerenone
(BAY 94-8862)
MR Antagonist
Chronic heart failure (CHF)
Diabetic nephropathy (DN)
Phase IIb in CHF and
phase II in DN
ongoing
Molidustat
(BAY 85-3934)
HIF-PH Inhibitor Anemia Phase IIb ongoing
Vericiguat
(sGC-Stimulator BAY 1021189)
sGC Stimulator
Worsening chronic heart
failure
Phase IIb ongoing;
collaboration with
Merck & Co. Inc.
Vilaprisan (sPRM)
(BAY 1002670)
Progesterone
Receptor
Antagonist
Symptomatic uterine
fibroids
Phase IIb ongoing
MR: Mineralocorticoid receptor; NHL: Non-Hodkin´s lymphoma
HIF-PH: HIF prolyl hydroxylase; sGC: Soluble guanylate cyclase;
sPRM: Selective progesterone receptor modulator
Positive Proof-of-Concept Increases
Confidence in NME-quality
• Bayer Investor Presentation • Meet Management • June 2014Page 75
NME: New molecular entity
CHF: Chronic heart failure
EPO: Erythropoietin
Copanlisib
Finerenone
Molidustat
Vericiguat
(sGC-Stimulator)
Vilaprisan
(sPRM)
100% of patients (6/6) with follicular lymphoma achieved
a partial response as best response in phase I
Phase II results in CHF patients suggest improved safety
with at least similar efficacy compared to spironolactone
Improvement in important cardiological parameters
observed in phase I
Significant increase in levels of endogeneous EPO and
reticulocytes demonstrated in phase I
Phase IIa data demonstrated reversible induction of
amenorrhea
• Bayer Investor Presentation • Meet Management • June 2014Page 76
Copanlisib (BAY 80-6946) –
A PI3K-Inhibitor in Phase II in Cancer
● In most tumor cells, the PI3K-signaling
cascade is activated and provides
important tumor growth and survival
signals
● Copanlisib is a pan class I PI3K-inhibitor
with dominant  activity
● Copanlisib has shown a broad anti-
tumor spectrum in preclinical tumor
models
● Phase II in Non-Hodgkin’s lymphoma is
ongoing; completion expected 1H 2015
Phosphatidylinositol-3 kinases (PI3K)
play a central role in cellular signal
transduction processes
Copanlisib
• Bayer Investor Presentation • Meet Management • June 2014Page 77
Copanlisib Has Shown Substantial Activity in
Follicular Lymphoma
*Data from Patnaik A et al.; ASH 2012; 18FDG-PET: 18fluorodeoxyglucose -
positron emission tomography
18FDG-PET scans of a follicular lymphoma
patient with partial response
● Phase I trial successfully completed
● 100% of patients (6/6) with
follicular lymphoma (FL)
responded to therapy achieving a
partial response as best response*
● Maximum response duration > 840
days
● Encouraging signals in diffuse
large B cell lymphoma patients
● 18FDG-PET data suggest that
Copanlisib has rapid antitumor activity
52-year-old female with FL, grade 1-2, diagnosed stage IVa
• Bayer Investor Presentation • Meet Management • June 2014Page 78
Selective Progesterone Receptor Modulation
for Treatment of Uterine Fibroids
● Uterine fibroids are the most common
benign tumors in women of reproductive
age: 5-10% of premenopausal population
suffers from symptomatic fibroids
● Symptoms may include heavy menstrual
bleeding and tumor size related symptoms
● Current therapies include surgical
procedures or short-term use of GnRH
analogs for estrogen depletion
● Growth of fibroids strongly depends on
progesterone and estrogen
● Progesterone receptor modulation may
offer long-term treatment of uterine fibroids
without estrogen depletion side effects of
GnRH analogs
GnRH: Gonadotropin-releasing hormone
sPRM: Selective progesterone receptor modulator
PR
Transcription
Activation
Endometrial
Modulation &
Fibroid Growth
sPRM
Transcription
Endometrial
Modulation &
Fibroid Growth
PR
• Bayer Investor Presentation • Meet Management • June 2014Page 79
Vilaprisan (sPRM; BAY 1002670) – For the
Treatment of Symptomatic Uterine Fibroids
● Vilaprisan is a novel oral, highly potent
and selective progesterone receptor
modulator
● Exhibits marked efficacy in an
innovative humanized fibroid disease
model1
● Phase IIa data (N=67) showed proof of
concept including:
● Reduction of bleeding: induced
amenorrhea (non-bleeding) in >60%
of women treated with dosages
>1mg/day
● Reversal of amenorrhea after
treatment cessation
● No prohibitive safety findings
1 Wagenfeld et al. Hum Reprod. 2013 Aug;28(8):2253-64
Phase IIa data BAY Vilaprisan
Dose effect curve for amenorrhea rate
0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5
0102030405060708090100
Point estimate (median)
90% Credible interval
Observed rate
Efficacy threshold
Dose (mg)
Amenorrhearate(%)
• Bayer Investor Presentation • Meet Management • June 2014Page 80
Renal Anemia is an Important Area of Unmet
Medical Need
● Diseased kidneys do not produce
sufficient levels of erythropoietin (EPO)
in response to hypoxia, leading to
anemia
● CKD/ESRD is the leading cause of
anemia in industrialized countries
● Substitution with parenteral EPO is
standard of care – however, un-
physiologically high EPO doses
correlate with significant side effects
● There is a need for novel therapies that
lack the side effects of high doses of
EPO-substitution
CKD: Chronic kidney disease
ESRD: End-stage renal disease
Anemia
Low oxygen
level (Hypoxia)
Normal kidney
function
Impaired kidney
function
EPO
Red blood cell
formation
EPO
Normal red blood
cell count
Insufficient
formation of
red blood cells
• Bayer Investor Presentation • Meet Management • June 2014Page 81
Molidustat – An Oral HIF-PH Inhibitor for
Treatment of Renal Anemia
Increased red blood
cell production
Inhibition of HIF-PH increases the
stability of HIF resulting in production of
endogeneous EPO - potential novel
therapeutic approach for the treatment
of renal anemia
Under normal oxygen conditions, HIF
gets hydroxylated by HIF-PH and then
degraded
Under hypoxia conditions, HIF is
activated and induces the synthesis of
erythropoietin (EPO) in the kidneys
which stimulates red blood cell
formation
Nucleus
HIFHIF
Low oxygen levels
HIF
Hydroxylation
HIF
Normal oxygen levels
HIF-PH
O2
hHIFhHIF
Degradation
Degraded HIF
HIFHIF
Inhibition of HIF-PH in renal anemia
HIF-PH
O2
EPO ↑
Nucleus
EPO ↑
Nucleus
Increased red blood
cell production
HIF: Hypoxia-inducible factor
HIF-PH: HIF prolyl hydroxylase (enzyme)
hHIF: hydroxylated HIF
• Bayer Investor Presentation • Meet Management • June 2014Page 82
Molidustat (BAY 85-3934) –
Proof of Concept Demonstrated
EPO: Erythropoietin
HIF-PH: HIF prolyl hydroxylase
● Molidustat is a novel oral inhibitor of the
enzyme HIF-PH
● In development for the treatment of
anemia associated with chronic kidney
disease
● Phase I in healthy subjects showed:
● Significant increase of EPO levels
after ≥ 12.5 mg
● Significant increase of reticulocytes
for doses ≥ 37.5 mg
● No prohibitive safety findings
Maximal EPO concentration after single
dose administration of Molidustat (Phase I)
0
10
20
30
40
50
Placebo 5 mg 12,5 mg 25 mg 37,5 mg 50 mg
EPO[U/L]
Dose
• Bayer Investor Presentation • Meet Management • June 2014Page 83
MR-Inhibition is a Proven Principle in the
Treatment of Heart Diseases
MR: Mineralocorticoid receptor
HF: Heart failure
aldosterone / cortisol
Overactivated
MR
causing e.g. 
 Na+ and water retention
 K+ loss
 Hypertensive effects
 Vascular 
inflammation/injury
 Myocardial/renal fibrosis
 Proteinuria
MR antagonist
KidneyHeart
 MR has multiple functions:
 Regulation of salt, fluid homoestasis
and blood pressure
 Mediator of oxidative stress,
subsequent inflammation, fibrosis and
cardiorenal disease
 Steroidal MR antagonists spironolactone
and eplerenone have been shown to be
effective in reducing cardiovascular
mortality in patients with HF but are
underutilized due to the risk of
hyperkalaemia, renal dysfunction and
anti-androgenic / progestogenic side
effects
 Steroidal MR antagonists are not
approved for kidney diseases eg. diabetic
nephropathy
• Bayer Investor Presentation • Meet Management • June 2014Page 84
Finerenone – A Novel Non-Steroidal and
Selective MR-Antagonist
CHF: Chronic heart failure; CKD: Chronic kidney disease
BNP: Brain natriuretic peptide;
B. Pitt et al., Eur. Heart J. 2013; doi:10.1093/eurheartj/eht187
Mean increases in serum potassium concentration
Finerenone10mg o.d.: 0.21 mmol/l
Spironolactone: 0.45 mmol/l
P <0.001
Mean change in estimated glomerular filtration rate
Finerenone10mg o.d.: -2.69 ml/min/1.73m²
Spironolactone: -6.70 ml/min/1.73m²
P <0.05
Median change from baseline in NT-proBNP
Finerenone 10mg o.d.: -193 pg/mL
Spironolactone: -170 pg/mL
(descriptive analysis)
Decreased BNP/NT-proBNP – a key
parameter for cardiac stress
Indicates lower incidence of
hyperkalaemia
Indicates lower incidence of worsening
of renal function
Phase II results suggest improved safety with at least similar efficacy on key
cardiac and renal parameters compared to spironolactone
Data at Day 29 +/- 2 in part B of the study with 392 pts in total;Spironolactone was given at an initial dose of 25mg o.d. and uptitrated to 50mg o.d.
on day 15±1 if sodium potassium concentration remained ≤4.8mmol/L; * eGFR 30-60 ml/min/1.73m²
Key phase II findings in patients with CHF and moderate* (part B) CKD :
• Bayer Investor Presentation • Meet Management • June 2014Page 85
sGC Modulation Has Significant Potential
 Cardiovascular diseases to be the
#2 therapeutic area by 2019**
 Significant areas of unmet medical
need including heart failure,
forms of pulmonary hypertension,
resistant hypertension, etc.
 Recently discovered mechanism
of sGC modulation holds promise
to address several areas of unmet
need
Unmet Medical Need in
Cardiovascular Diseases
sGC Modulation
*
sGC: Soluble guanylate cyclase; *cyclic guanosine monophosphate
**DecisionResources 2014
Strategic Pharma sGC Collaboration with
Merck & Co. Inc.
 Maximize potential of all pipeline assets
 Leverage R&D expertise in cardiovascular
 Improve funding capabilities – thereby maximizing commercial
potential of pipeline assets
 Optimize combined marketing & sales power
Collaboration between Merck and Bayer on sGC modulation to
Page 86
Joint development and commercialization strategy with global
50-50 cost and profit sharing
Merck to pay Bayer up to $2.1bn, comprising $1.0bn up-front
and up to $1.1bn in contingent milestone payments
• Bayer Investor Presentation • Meet Management • June 2014
Maximizing the Potential of sGC Modulation
 Bayer has marketing rights in Americas;
Merck in all other territories
 Co-promotion option for both parties in
territories of other party
 Enables Bayer to build its commercial
presence in US specialty pharma while
maximizing value of Adempas
*scope defined by sGC mechanism
Adempas (Riociguat) Vericiguat (BAY 1021189)
 Merck has marketing rights in Americas;
Bayer in all other territories
 Co-promotion option for both parties in
territories of other party
 Maximizes value of Vericiguat by
leveraging Merck’s US strength
Early/Future Pipeline Assets*
 Option to include other sGC pipeline assets (of both parties) that successfully complete
Phase 1 in the next 5 years
 Global 50/50 cost/profit split; joint development and commercialization strategy
Page 87 • Bayer Investor Presentation • Meet Management • June 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 88
sGC Stimulation to Address Unmet Medical
Need in Patients with Heart Failure
● Worsening chronic heart failure is an
established indication with high medical
need
● Limitations of standard of care include
tolerance, oxidative stress, endothelial
dysfunction and venoselectivity
● sGC stimulation can improve
hemodynamics via restoration of
cardiac and vascular cGMP signaling
● sGC stimulation may provide a new
principle to reduce event rates in
patients with worsening chronic heart
failure
Clinicalstatus
Patients who require hospitalization due to HF
(worsening HF) have a poor prognosis with high
rates of re-hospitalization and death
sGC: Soluble guanylate cyclase
HF: Heart failure
• Bayer Investor Presentation • Meet Management • June 2014Page 89
Vericiguat (sGC Stimulator; BAY 1021189) –
Improvement of Cardiovascular Function
sGC: Soluble guanylate cyclase
HF: Heart failure
Phase I of Vericiguat show improved cardiac
output (n = 36)
Fi gur e: Means and st andard devi at i ons f or i mpedance cardi ography over t i me f or Cardi ac Out put (L/ mi n) over t i me (val i d f or PD)
Day 1
0H 00M 1H 00M 2H 00M 3H 00M 4H 00M
3. 0
3. 5
4. 0
4. 5
5. 0
5. 5
6. 0
6. 5
7. 0
 Placebo
 5 mg
 7.5 mg
 10 mg
0 1 2 3 4
Time (h)
33.544.55.05.56.06.57.0
 Vericiguat is a novel sGC stimulator
suitable for once-a-day dosing
 Phase I successfully completed –
improvement observed in important
cardiological parameters, including:
 Cardiac output / index (“volume of
blood pumped by the heart”)
 Systemic vascular resistance
 Stroke volume
 No untoward safety findings in phase I
 Collaboration with Merck & Co (50/50
cost/profit split), joint development and
commercialization strategy
Cardiacoutput(L/min)
The New sGC Franchise is Strong
in the Industry
Phase I Phase III Submitted LaunchedPhase IIIndicationProject
PAH/CTEPH
PH-IIP
dSSc
CF
wCHF
PH
PH-HF
Adempas
Vericiguat
MK 8892*
rHT
Research*
in preparation
in preparation
in preparation
Research/
Preclin.
• Bayer Investor Presentation • Meet Management • June 2014Page 90
PH: Pulmonary hypertension; PAH:Pulmonary arterial hypertension;
CTEPH: Chronic thrombmoembolic PH; PH-IIP: PH assoc. with interstitial idiopathic
pneumonia; dSSc: Diffuse systemic sclerosis; CF: Cystic fibrosis; wCHF: Worsening
chronic heart failure; rHT: Resistant hypertension; HF: Heart failure
*Potential collaboration assets, subject to execution of options in the next 5 years after successful completion of Phase 1
BAY sGCstim
*
BAY sGCact
*
Raynaud’s
Major Expected Pharma Pipeline Newsflow
2014/2015
• Bayer Investor Presentation • Meet Management • June 2014
Estimated primary study completion as of May 2014
HCC: Hepatocellular carcinoma; NHL: Non-Hodkin‘s lymphoma;; MR: Mineralocorticoid receptor; HF: Heart failure;
PI3-Kinase: Phosphatidylinositol-3 kinases, sGC :Soluble guanylate cyclase; HIF-PH: HIF prolyl hydroxylase
Page 91
2014
2015
BAY 85-8501 (Elastase Inhibitor) Completion of phase II in bronchiectasis
Copanlisib (PI3-Kinase Inhibitor) Completion of phase II in NHL
Stivarga Completion of phase III in 2nd-line HCC
Finerenone (MRAntagonist) Completion of phase II in diabetic nephropathy
Vericiguat Completion of phase II in worsening chronic HF
Molidustat (HIF-PH Inhibitor) Completion of phase II
Finerenone (MR Antagonist) Completion of phase II in worsening chronic HF
Nexavar Completion of phase III in breast cancer (RESILIENCE)
Vilaprisan (SPRM) Completion of phase II
• Bayer Investor Presentation • Meet Management • June 2014
Established Pharma Products
Page 92
2010 2011 2012 2013
Hemophilia Franchise –
Stable Growth
• Bayer Investor Presentation • Meet Management • June 2014
 Global # 2 in hemophilia A treatment
 Competitive portfolio in hemophilia:
 Positive phase III data with site-
directed PEGylated long-acting
Factor VIII (BAY 94-9027)
 Product from plasma-free
process (BAY 81-8973) – filing
planned for 2014
 Investment of € >500m planned to
establish additional manufacturing
capacities for recombinant FVIII
products in development
Sales in € million; ∆% Fx adj.
299
705
290
785
332
850
US Rest of the world
1,004
1,075
1,182
+6%
Page 93
330
872
1,202
Prophylaxis in Hemophilia – Breakthrough in
Prolonging Dosing Intervals
• Bayer Investor Presentation • Meet Management • June 2014Page 94
 Prophylaxis can protect hemophilia patients more effective compared to on-
demand treatment in terms of
 Reducing frequency and severity of bleeding episodes
 Preserving joint health/function and
 Maintaining overall long-term health status
 However, current standard in prophylaxis involves two to three infusions per
week
 A long-time goal in hemophilia prophylaxis has been to reduce the burden
from frequent infusions
 PROTECT VIII demonstrated evidence of reliable prophylaxis of bleeding in
hemophilia A with dosing at every 5 and 7 day intervals
Expanding the Hemophilia Franchise – Long-
Acting Site-directed PEGylated Factor VIII
• Bayer Investor Presentation • Meet Management • June 2014Page 95
 Damoctocog alfa pegol (BAY 94-
9027) is a B-domain–deleted
recombinant factor VIII (BDD-rFVIII)
with site-specific PEGylation
 Attachment of PEG extends half-life
without reducing FVIII activity
 Positive PROTECT VIII phase III
data
 Filing US, EU and other regions
planned for 2H’2015
Site-specific
PEGylation to
extend FVIII
half life
B-domain
deletion
Damoctocog alfa pegol (BAY 94-9027) –
Design of the PROTECT VIII Phase III Study
• Bayer Investor Presentation • Meet Management • June 2014Page 96
 PROTECT VIII is a pivotal study assessing safety and efficacy of the site-
directed PEGylated FVIII Damoctocog alfa pegol
 Part A: On-demand and prophylactic treatment (completed)
 Part B: Major surgery (ongoing)
6
Randomization
0 10 14 20 28weeks
2x/week 25 IU/kg (n  120)
2 or more breakthrough bleeds:
No or 1 breakthrough bleeds:
36                   
Screening
Screening
2  
On‐demand therapy individual dosage n=20
2x/week 30 to 40 IU/kg n=24*
Every 5 days 45‐60 IU/kg n=43
Every 7 days 60 IU/kg n=43
* 13 assigned due to bleeding; 11 default/randomization arms full
38
Damoctocog alfa pegol Phase III Results -
Reduction of Infusion Frequency in Prophylaxis
• Bayer Investor Presentation • Meet Management • June 2014Page 97
 Met primary objective of protection from bleeds with fewer infusions
 Extending infusion intervals up to 7 days resulted in protection from bleeds
 No inhibitors against FVIII developed during treatment period
Study Arm
Patients (n)
remaining on
treatment
Patients with no
bleeding
Median ABR
Prophylaxis: infusion
2x/week
n.a. n.a.
17.4 (reduction to 4.1 after
dose increase)
Prophylaxis: infusion
every 5 days
43/43 44% 1.9
Prophylaxis: infusion
every 7 days
32/43
37%
(incl. non-completers)
3.9 *
(incl. non-completers)
On-demand treatment n.a. n.a. 23.0
ABR: Annualized bleeding rate
*Median ABR for the 32 (74%) completers was 0.96
The Leader in Women’s HealthCare
• Bayer Investor Presentation • Meet Management • June 2014
Yaz family
Sales ∆% y-o-y, () FX adj.
Women’s Healthcare 2013
€3,034m
-7% (-1%)*
+6 (+10)Mirena
-23 (-16)Diane
-18 (-13)
+7 (+12)Qlaira
Other products +1 (+7)
-13 (-8)Microgynon
-2 (0)Valette
-13 (-8)Meliane
-7 (-1)Angeliq
Page 98
* Fx & portf. adjusted growth -4% due to Essure with €74m sales in 2013
• Bayer Investor Presentation • Meet Management • June 2014
Strengthening Women‘s Health Business –
Acquisition of Conceptus, Inc.
 Bayer successfully completed the public tender offer to acquire all shares in
Conceptus for a purchase price of €780m
 US-based company developing the Essure® procedure, the leading non-
surgical permanent birth control method proven by >700,000 procedures
 Significant synergies expected from leveraging existing business power
Essure ®
Permanent
Long-term
Short-term
No children Active family planning Family planning finalized
IUD (Mirena)
IUD (Skyla)
Oral contraceptives (e.g. YAZ)
Page 99
Mirena – The Leading Hormonal Long-
Acting Contraceptive
• Bayer Investor Presentation • Meet Management • June 2014
 Intrauterine device, containing
levonorgestrel, for reversible long-
term contraception
 Life-cycle opportunities:
 Small low-dose long-acting (up to 3
years) device:
 Jaydess; launched in EU
 Skyla; launched in the US
 Phase III for a long-acting (up to 5
years), low-dose, small
contraception device underway
Sales in € million; ∆% Fx adj.
2010 2011 2012 2013
285
254
313
268
385
292
US Rest of the world
539
581
677
+10%
Page 100
415
304
719
Betaseron – Long-term Experience in
Multiple Sclerosis Treatment
• Bayer Investor Presentation • Meet Management • June 2014
 First interferon launched in multiple
sclerosis, introduced in 1993
 Wealth of clinical experience
 Demonstrating excellent efficacy and
tolerability
 21-year long-term follow-up study
demonstrated significant survival
advantage with Betaseron treatment
 Launch of BETACONNECT (new
electronic auto-injector) in Europe
underway
Sales in € million; ∆% Fx adj.
2010 2011 2012 2013
473
733
447
670
578
638
US Rest of the world
1,206
1,117
1,216 -12%
Page 101
499
539
1,038
Nexavar –
Our Cornerstone in Oncology
• Bayer Investor Presentation • Meet Management • June 2014
 Approved for kidney cancer (RCC),
liver cancer (HCC) and radioactive
iodine refractory differentiated thyroid
cancer (DTC)
 Only approved drug with overall
survival benefit in HCC
 Phase III trials in:
 Breast cancer
 RCC (adjuvant)
Sales in € million; ∆% Fx adj.
2010 2011 2012 2103
174
531
174
551
204
588
US Rest of the world
705 725
792
+3%
Page 102
219
552
771
Aspirin –
Sustainable for More Than A Century
• Bayer Investor Presentation • Meet Management • June 2014
 One of the world’s most recognized
brands
 Available as OTC and Rx Aspirin
 Bayer’s #1 product in Emerging
Markets; 8% growth in China in
2013
Sales in € million; ∆% Fx adj.
2010 2011 2012 2013
358
418
404
471
476
494
Rx-Aspirin OTC-Aspirin
776
875
970 -1%
Page 103
452
464
916
• Bayer Investor Presentation • Meet Management • June 2014Page 104
Aspire to Become the Leading
OTC Company
Evolution of Bayer Consumer Care’s
OTC Business
2008
Acquisition of OTC brand
portfolio from Sagmel
(CEE) and Topsun (China)
1999
Aspirin trademark
centenary-worldwide
sales > €500m
1899
ASPIRIN introduced
as an over-the-counter
(OTC) medicine
1994
Consumer Care business group
created by the acquisition of North
American OTC business of Sterling;
Acquisition of the “Bayer Cross”
Trademark in USA
2005
Acquisition of Roche
Consumer Health
2013
Aspirin trademark sales
of >€900m
Acquisition of
Steigerwald (Germany)
Page 105 • Bayer Investor Presentation • Meet Management • June 2014
2014
Proposed acquisition of Merck’s
Consumer Care business (US)
Transaction agreement signed with
Dihon Pharmaceutical Group (China)
• Bayer Investor Presentation • Meet Management • June 2014Page 106
Growth Strategy
 Maximize brand potential
 Global expansion of key brands
 Exploit our innovation pipeline
 Grow in emerging markets
 Increase commercial power
 Bolt-on acquisitions to strengthen
portfolio & regional set-up
3.4
3.5
3.9 3.9
2010 2011 2012 2013
+5%
+7%
+6%
Consumer Care sales in € billion; ∆% Fx & portfolio adj.
Bayer Consumer Care – Outperforming
Markets in Past 7 Out of 8 Years
Merck’s Consumer Care Business Fits
Perfectly With Bayer Consumer Care
• Bayer Investor Presentation • Meet Management • June 2014
Complementary
Portfolio
Building on core
competencies
 Creation of a global leader in OTC
 Gaining scale in key categories CASF1, dermatology,
and gastrointestinal
 Optimizing footprint in North America
 Strong track record of growing OTC brands
 Strong geographical presence to broaden Merck’s
portfolio globally
 Utilizing integration skills from past transactions
Page 107
Acquisition criteria
fulfilled
 Creating leadership positions in important consumer
care categories and geographies
 Increasing consumer care margin2 by ~1pp from year 1
 Immediate core EPS accretion from year 13
1 cold, allergy, sinus, flu; 2 EBITDA pre-special items;
3 transaction incl. sGC collaboration
Page 108 • Bayer Investor Presentation • Meet Management • June 2014
Combined Portfolio Significantly Strengthens
Global Positions
Gastrointestinal
Analgesics3
CASF2
Nutritionals
Dermatology1
Total
Others4
3,904 1,635 5,539
1,110 386
372 803
126 513
439 141
1,023
834
1 including sun care; 2 Cold, Allergy, Sinus, Flu; 3 including Cardio; 4 Foot Health, Women’s Health, Other
1,496
1,023
1,175
834
580
431
#1
#2
#3
#1
#2
Global position*2013 Sales in €m (pro-forma portfolio)
Note: Merck sales converted at average USD rate of 1.33 (FY 2013)
305
*After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx
MerckBayer
Page 109 • Bayer Investor Presentation • Meet Management • June 2014
Combined Portfolio Significantly Strengthens
Geographic Footprint
Note: Merck sales converted at average USD rate of 1.33 (FY 2013)
*After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx
Latin America
Europe
North America
Total
Asia/Pacific
3,904 1,635 5,539
1,117 1,105
1,621 170
389
513
141
777
2,222
1,791
946
580
#1
#1
#5
#2
Global position*2013 Sales in €m (pro-forma portfolio)
191
169
MerckBayer
FY 2013 sales in € million (∆% yoy Fx-adj.)
321
310
232
214**
207
176
158
257
*Total Aspirin includes Aspirin Complex and Aspirin Cardio (Rx)
**Total Alka-Seltzer includes Alka-Seltzer and Alka-Seltzer Plus
916*
= Rx Sales
Page 110 • Bayer Investor Presentation • Meet Management • June 2014
Combined Top 10 Portfolio –
Individual Brands with Annual Sales >€100m
576
Note: Merck sales converted at average USD rate of 1.33 (FY 2013); based on pro-forma FY 2013 net sales
• Bayer Investor Presentation • Meet Management • June 2014Page 111
Top Priorities To Be Executed Immediately
After Closing of Transaction…
 Ensure fast integration into operations
 Safeguard product supply
 Realize synergy potential
 Prioritize brand strategies within combined portfolio
 Realize Merck brand penetration opportunities ex-US
 Define and execute individual brand strategies
 Develop US scale advantage
 Strive for leadership with trade customers
 Provide a broader product portfolio
Critical mass
in US
Brand Roll-
Out ex-US
Smooth
integration
• Bayer Investor Presentation • Meet Management • June 2014Page 112
Clear Strategy For a Smooth Integration
2014 Q2 2014 Q42014 Q3 2015 (End State)
 Smooth integration expected due to experienced management team
• Ensure effective integration into Consumer Care
• Safeguard on-going product supply
• Prioritize and execute identified brand development / expansion strategies
• Ensure sufficient future capacity for growth
• Capitalize on Merck’s innovation capabilities
• Achieve scale and revenue synergies
• Capture consolidation and efficiency synergies by 2017
 Deal signing  Deal closing  Consolidation / Integration
• Bayer Investor Presentation • Meet Management • June 2014Page 113
Enhanced Scale and Broader Category
Scope Improve Product Offerings
US Retail Sales CASF Benefits from Enhanced Scale
 Co-promoting complementary
brands
 New item assortment and shelving
opportunities
 Improved merchandising efficiencies
 Bigger and more impactful trade
events
 Foster strategic partnerships with
retailers
FY 2013 retail sales in CASF in $ million*
$-
$200
$400
$600
$800
$1,000
$1,200
RB Bayer &
Merck
J&J Merck &
Co.
P&G Pfizer Chattem Bayer GSK
*Source: IRI; Latest 52WK; December 2013
 Make Bayer Consumer Care Top Strategic Partner for US Retailers
Maximizing Brand Potential Through
Global Expansion
Brand Sales by Major Region 2013 Expansion Plans
• Bayer Investor Presentation • Meet Management • June 2014Page 114
Analgesic
~80% in North America
~95% in North America
Wound-healing
~75% in Europe
Anti-fungal
~75% in Europe & LatAm
Vitamins & minerals
~50% in Europe
~80% in North America
CASF
Sun Care
• Bayer Investor Presentation • Meet Management • June 2014Page 115
Russia
Country OTC Market
Sales Growth
2013*
Execution Plans
China
 Global #2
 Growing 2x the
global rate
 Use investments in footprint, brand-building
and sales capabilities to extend Claritin
leadership
 Build sun care category with Coppertone
Brazil
 Global #7
 Fastest growing
market in LATAM
 Use investments in brand-building and
channel capabilities to develop key new
categories (sun care, foot care, allergy)
 Revitalize Coppertone and Dr. Scholl’s
brands
Russia
 Global #4
 Retail OTC is
largest healthcare
segment
 Focus on CASF brands using current
position to roll-out extended offerings
 Achieve #2 position
Execution Plan Focused on Key Brands in
Key Emerging Markets
+38%
+26%
+14%
*Bayer Consumer Care sales, currency-adjusted
Consumer Care is Well-Positioned for
Growth – Aspire to Clear OTC Leadership
OTC Market
Attractive
Bayer Has
Strong #2
Position
Plans for
Continued
Future Growth
 Trends favor continued growth
 OTC market model based on long-term brand building
 OTC businesses becoming more valuable over time
 Leader in key categories
 Multiple strong brands
 Track record of outperforming market growth
 Globalize established brands & launch innovation pipeline
 Focus on emerging markets where most of growth will come
 Strategic acquisitions and alliances
Page 116 • Bayer Investor Presentation • Meet Management • June 2014
• Bayer Investor Presentation • Meet Management • June 2014Page 117
Animal Health – Operating in an
Attractive Market Environment
• Bayer Investor Presentation • Meet Management • June 2014Page 118
Demonstrating a Solid, Long-Term Sales
Growth Trajectory
Sales in € million; ∆% Fx & portfolio adj.
 Overall global #5 and global #2 in
parasiticides
 Ranked #3 in CAP (~60% of sales)
 Sector driven by:
 Emotional relationships to pets
 Infectious and chronic diseases
 Ranked #7 in FAP (~40% of sales)
 Sector driven by:
 Increasing customer/consumer
awareness
 Food safety & disease transmission
 Globalization in farm exports
Highlights
977
1,120
1,186
1,303 1,306
2009 2010 2011 2012 2013
+4%
• Bayer Investor Presentation • Meet Management • June 2014Page 119
Aspiring Further Sustainable Growth
6%
AH Market 2013 by Player
Zoetis Merck Merial Elanco Bayer
Boehringer I. Novartis Virbac CEVA Others
€21bn
Growth Strategy
 Expand market share of existing
portfolio while delivering innovation
 Strengthen and expand 2013 acquired
TEVA US AH business
 Drive research & development at a 10%
sales ratio
 Explore M&A opportunities for further
growth
• Bayer Investor Presentation • Meet Management • June 2014Page 120
New Innovative Product Examples –
Recent Launch Highlights
 New benchmark for flea
and tick protection
 Outstanding efficacy
based on combination of
active ingredients
 Up to 8 months protection
due to innovative polymer
matrix technology
 Pradofloxacin, the new
generation fluoroquinolone
 Extended spectrum vs.
previous fluoroquinolones
 Greater potential to limit
selection for resistance
 Convenient formulations
for dogs and cats
 1st combined endopara-
siticide against
roundworm and coccidia
in dogs
 Easy and convenient
once daily oral treatment
 Can be used at 2-weeks
old
• Bayer Investor Presentation • Meet Management • June 2014Page 121
Innovative Life-Cycle Management –
Example of Advantage Family
Highlights
2002 2013
202
487
Sales in € million
 Successful franchise through:
 Brand building – investments in
direct-to-consumer for brand
awareness
 Channel diversification – meeting
consumers where they are
 Life Cycle Management (LCM) –
ongoing with new claims
• Bayer Investor Presentation • Meet Management • June 2014Page 122
Selected R&D Activities
New
formulations Antimicrobials
Pharmaceutical
SpecialtiesParasiticides
Focus to improve:
 Convenience
 Efficacy
 Safety
 Antibiotics
(Quinolones)
 Dairy Health
 Respiratory
Diseases
Products
 Allergy &
Inflammation
 Chronic Kidney
Disease
 Ecto-
parasiticides
 Endo-
parasiticides
 Endecto-
parasiticides
R&D Investment approx. 10% of turnover
• Bayer Investor Presentation • Meet Management • June 2014Page 123
Medical Care – Diabetes Care
and Radiology
DC & R
• Bayer Investor Presentation • Meet Management • June 2014Page 124
Radiology &
Interventional
Diabetes
Care
Sales Split 2013
Medical Care €2,526m; -5% (0%)
40% 60%
Medical Care – Strong Legacies in Diabetes
Care and Radiology
In € million, ∆% yoy, () = Fx & portf. adjusted
Diabetes Care:
 Comprises self testing blood
glucose monitoring devices
Radiology
 Combines our Contrast
Media, Injector and
Informatics businesses
• Bayer Investor Presentation • Meet Management • June 2014Page 125
Diabetes Care –
Global Player in Blood Glucose Meters
Highlights
Sales in € million; ∆% Fx & portfolio adj.
1,000 993 1,002
1,047
1,007
2009 2010 2011 2012 2013
-1%
 Global #3 in blood glucose meters
 Stable business performance despite
difficult market conditions
 Market characterized by growth in
prevalence, but pricing pressure
 Latest innovation products include
CONTOUR® Next and Next Link
 MULTIPULSE technology ensures high
accuracy blood glucose measurements
 Wireless transmission of results to Medtronic
insulin devices
• Bayer Investor Presentation • Meet Management • June 2014Page 126
1,363
1,474 1,498
1,606
1,519
2009 2010 2011 2012 2013
Sales in € million; ∆% Fx & portfolio adj.
0%
Radiology – Leading Positions in Contrast
Media and Application Devices
 Integrated subsidiary Medrad Inc. and
our contrast media business
 The business comprises:
 Contrast media: CT and MRI
 Contrast media injectors: Medrad
brand
 Informatics
 Services
 Synergies through focus on similar
centers / physicians
Highlights
Investor Handout – Meet Management
Bayer CropScience
June 2014 – New York
18%
25%
11%
11%
7%
28%
Sales 2013: €8,819m
Insecticides€1,622m
Market position:
Fungicides€2,195m
3Market position:
SeedGrowth€921m
1-2Market position:
Herbicides €2,456m
4Market position:
Env. Science €651m
1Market position:
Seeds €974m
7Market position:
Page 128
CropScience –
A Leader in Chemical Crop Protection
• Bayer Investor Presentation • Meet Management • June 2014
1
Market positions based on company reportings and Cropnosis estimates
Page 128
25%
22%
14%
12%
8%
6%
6%
4%3%
Fruits & Vegetables
CerealsOilseeds
Soy
Corn
Cotton
Rice
Sugar Crops
* by major crop groups excluding industrial business and non-agricultural solutions
CropScience Sales 2013*
Other
Fruits, Vegetables and Cereals –
A Major Part of Our Portfolio
• Bayer Investor Presentation • Meet Management • June 2014Page 129
Leading the Way in Integrated Crop
Solutions
Integrated Crop Solutions
Chemical
Crop
Protection
Biological
Crop
Protection
Seeds
 Herbicides
 Fungicides
 Insecticides
 SeedGrowth
 Microorganisms
 Microbial
extracts
 Canola, cotton,
rice, vegetables,
soy, wheat
 Conventional
seeds
 GMO seeds
 Traits
 Weed, pest &
disease control
 Stress
tolerance
Better harvest
with improved:
 Yield
 Quality
 Processability
 Sustainability
GMO: Genetically modified organism
• Bayer Investor Presentation • Meet Management • June 2014Page 130
• Bayer Investor Presentation • Meet Management • June 2014Page 131
Strong Growth at
Record Margin
FY 2013 –
Strong Growth at Record Margin
Page 132
Crop Protection
+7% (+11%)
Environmental
Science
-4% (+1%)
*before special items
Seeds
+1% (+1%)
2013 Sales Earnings
In € million, ∆% yoy, () = Fx & portf. adjusted
CropScience €8,819m; +5% (+9%)
Price
+3%
Volume
+7%
Fx
-5%
Portfolio
0%
7,194
FY‘12 FY‘13 FY‘12 FY‘13
2,025
2,248 +11%
1,543
1,801 +17%
Adj.
EBITDA*
Adj.
EBIT*
651
974
24.2% 25.5%Margin
• Bayer Investor Presentation • Meet Management • June 2014
Emerging Economies
25%
CropScience Sales in FY 2013
CropScience €8,819m; +5% (+10%)
Latin
America
Eastern
Europe
Africa &
Middle East
Emerging
Asia³
~900
+11% ~2,200
+27%
~600
+9%
~300
+4%
Page 133
17%
USA
+3%
25%
45%
13%
Emerging
Economies¹
+18%
Western
Europe +3%
Others²
+6%
FY 2013 –
Strong Growth in Emerging Economies
Sales in € million, ∆% yoy Fx adjusted
• Bayer Investor Presentation • Meet Management • June 2014
1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe
2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand
• Bayer Investor Presentation • Meet Management • June 2014
Successful Start to The Year
Page 134
Sales Earnings
Q1 2014 – CropScience:
Early Start to the Season in Europe
Page 135
Crop Protection
+6% (+12%)
Environmental Science
+1% (+8%)
Seeds
+3% (+12%)
In € million, ∆% yoy, () = Fx & portf. adjusted
CropScience €2,900m; +5% (+12%)
Price
+2%
Volume
+10%
Fx
-7%
Portfolio
0%
2,231
Q1‘13 Q1‘14 Q1‘13 Q1‘14
1,081 1,098 +2%
969 988 +2%
Adj.
EBITDA*
Adj.
EBIT*
166
503
• Bayer Investor Presentation • Meet Management • June 2014
*before special items
Herbicides
Fungicides
Seeds
503
+12%
Insecticides
Sales in € million; ∆% y-o-y Fx & portfolio adj.
Q1 2013 Nominal growth Q1 2014
• Bayer Investor Presentation • Meet Management • June 2014
Env.
Science
Q1 2014 – Growth Driven by All Segments
Page 136
965
+8%
662
+17%
352
+13%
252
+ 19%
166
+ 8%
Seed
Growth
 Strong demand for cereal herbicides
in Europe
 Early start to the season in Europe;
Growth in LatAm mainly driven by Fox
 High demand in the US, especially for
Poncho family in corn and soybean
 Marked sales increase in Europe and
LatAm; excellent performance of Belt
 Growth in the Americas, mainly driven
by cotton and vegetable seeds
 Positive performance for both
professional and consumer business
• Bayer Investor Presentation • Meet Management • June 2014
Customer-Centric Strategy
Pays Off
Page 137
Customer-Centric Strategy Pays Off
Strengthen
Customer Centricity
Lead the Way
in Innovation
Enhance
Crop Protection &
Environmental Science
 Striving for first- and
best-in-class
solutions
 Exploiting expertise
in seeds, breeding,
and chemical and
biological crop
protection
 Driving commercial
excellence in
marketing and sales
 Connecting partners
in the value chain
through integrated
Go-to-Market
practices
 Improving portfolio
through focused
and integrated
crop solutions
 Increasing
flexibility and
efficiency
Expand
Seeds Business
 Further strengthening
position in
vegetables, rice,
oilseed rape
and cotton
 Extending portfolio
by building up
business in soybean
and wheat
• Bayer Investor Presentation • Meet Management • June 2014Page 138
Q1 2014 - Significant Contribution from
New Crop Protection Products
1.1
1.5
1.8
2.6
2012 2013 2014e 2016e
+33%
Sales from new Crop Protection products
launched since 2006 in €bn
∆% y-o-y, () Fx adj.
• Bayer Investor Presentation • Meet Management • June 2014
 (+16%) - Superior ‘all-in-one’
cereal fungicide with yield-boosting
effect
 herbicide (+14%) -
Excellent weed control in corn and
cereals, also in case of glyphosate
resistance
 (+75%) - Broad-spectrum
insecticide with fast, long-lasting
action
 (+112%) - New fungicide now
available in several key markets
Q1 2014 Highlights
Q1
0.6
Page 139
Xpro – New Cereal Fungicide
with Yield-Boosting Effect
 Pyrazole fungicide from a new generation of SDHI* for foliar use in cereals
 Combined formulation of Bixafen and Prothioconazole leading to superior
"all-in-one" cereal fungicide Xpro
 Excellent control of key cereal diseases including strobilurin-resistant Septoria
 Boosting yield through long-lasting disease control and positive impact on
plant physiology
 Global peak sales potential of more than €300m
* SDHI: Succinate dehydrogenase inhibitor
• Bayer Investor Presentation • Meet Management • June 2014Page 140
Luna – Outstanding Fungicide for Managing
Problematic Crop Diseases
 New SDHI* fungicide for use in foliar application and seed treatment on more
than 70 horticultural and industrial crops
 Control for a broad range of problematic diseases including Alternaria blight,
scab, powdery mildew and white mold
 Benefits for the food chain through better storability and longer shelf-life of
harvested produce
 Available since 2012 planting season in several key markets
 Global peak sales potential of more than €250m
* SDHI: Succinate dehydrogenase inhibitor
• Bayer Investor Presentation • Meet Management • June 2014Page 141
Adengo Family – Highly Effective Weed
Control in Corn
 Thiencarbazone-methyl is a new sulfonyl-amino-
carbonyl-triazolinone (SACT) herbicide
 Additional crop selectivity in combination with
HPPD inhibitor Isoxaflutole and safener Cyprosulfamide
Grower benefits:
 Controls annual grasses and broad leaved weeds in
corn including those that are resistant to glyphosate
 Offering flexibility in application timing
 Strong enough to achieve one-pass weed control
 Rapid burndown, long-lasting residual control
• Bayer Investor Presentation • Meet Management • June 2014
Peak sales potential of more than €350m
Page 142
Belt Insecticide - Preserve Yield Potential
 Flubendiamide is a phthalic acid diamide
 Acts as ryanodine receptor modulator, larvae loses
muscle control
Grower benefits:
 Controls lepidoptera pests in a wide range of crops,
including soybeans, corn and cotton
 Fast action, larvae stops feeding immediately
 Rainfast with excellent residual activity
 Provides minimal risk to beneficial insects
 Excellent resistance management tool
• Bayer Investor Presentation • Meet Management • June 2014
Control
+ BELT®
Heliothis
Peak sales potential of more than €300m
Page 143
Sustainable Alternatives to Fight Glyphosate
Weed Resistance
• Bayer Investor Presentation • Meet Management • June 2014
 Weed resistance to glyphosate increasingly impacting crop production;
almost 50% of U.S. growers are affected
 Our LibertyLink is currently the only non-selective herbicide solution to
glyphosate resistant weeds
 Significant expansion of production capacity for Liberty planned
 We are committed to develop new and more sustainable weed
management solutions
 Highly effective pre-emergent and selective herbicide portfolio launched
100
200
300
400
2010 2011 2012 2013
Liberty/Basta Sales in €m
Page 144
Future Market Potential of Biologicals
Expected to Increase Significantly
 Biologicals are products derived from naturally-occurring living organisms or
materials from plants or microorganisms
 Increasing demand from consumers for safe and sustainably produced food,
especially in fruits & vegetables area
 Global retailers have more stringent residue reduction targets
 Currently lower regulatory hurdles and faster registration process for
biologicals compared to chemicals
 Grower benefits from short pre-harvest and re-entry intervals and thus high
flexibility on application timing
 When used in combination or rotation with chemicals, biologicals provide new
tools in resistance management
• Bayer Investor Presentation • Meet Management • June 2014
Market potential expected to triple from $1.2bn in 2010 to $4bn in 2020
Page 145
Further Growth Opportunities in Biologicals
with Bolt-On Acquisitions
 Successful market entry with nematode seed treatment Poncho/Votivo in 2011
(Sales 2013: €150m)
 AgraQuest acquired in Q3 2012 for €375m including milestone payments.
Global provider of innovative biological pest management solutions based
on natural microorganisms
 Prophyta acquired in Q1 2013, a provider of well-established products,
e.g. nematicide BioAct
 Biagro acquisition* adds nitrogen inoculants and plant health promoters
 We aim to become the world leader in integrated crop solutions
• Bayer Investor Presentation • Meet Management • June 2014
* Clearance by Antitrust Authority in Argentina outstanding
Page 146
Acquisition of Biagro to Strengthen our
Soybean Business in Latin America
 Argentinean company Biagro acquired in Q1 2014*
 Biagro portfolio includes seed-applied biofertility
inoculants and plant growth-promoting microorganisms
 Acquisition is a further milestone to become a leader in
biological seed treatments
 Provides soybean growers in Latin America with
innovative offerings to substantially improve productivity
 Nitrogen essential for plant growth and soybean seed
production
 Biagro inoculants are a very effective and cost-efficient
method of supplying nitrogen to soybeans and other
legume crops
• Bayer Investor Presentation • Meet Management • June 2014
* Clearance by Antitrust Authority in Argentina outstanding
Inoculants containing
high-quality Rhizobium
bacteria strains enable
plant roots to fix nitrogen
from the atmosphere,
resulting in enhanced
plant growth, more
vigorous root structure
and greener plant foliage
Page 147
Customer Centricity Along the Entire
Value Chain
• Bayer Investor Presentation • Meet Management • June 2014
Bayer CropScience
Our offers Growers
Distributors/
seedcompanies
Retailers
Advisors
Providing Seed-to-Shelf Solutions
Traders
Foodprocessors
Foodretailers
Consumers
 Around 240 food chain partnerships covering most of the
main fruit & vegetable crops and rice
 Premium seeds and effective crop protection products to maximize yield
 Consistent and high harvest quality for efficient food processing
 Meeting highest food safety standards
 Better product quality for the consumer
Page 148
Serving Grower Needs Beyond
Crop Protection and Seeds
• Bayer Investor Presentation • Meet Management • June 2014
Services Examples
Providing agronomic support
 Crop advice
 Expert trainings
 On-farm trials
 Field days
Optimizing yield and quality by
offering diagnostic and prediction
tools
 Weather forecast
 Pest prediction
 Disease diagnosis
 Resistance risk
calculator
 Assessment of quality
indicators
Helping to optimize application
process and seeding
 Application
collaborating with
machinery providers
 Seed treatment
equipment checks
Creating transparency by offering
tracking / documentation support
 Field documentation
 RoI calculation
 Certification support
Improving farm management by
financing and insurances
 Ag input financing
 Barter business
 Crop price insurance
Page 149
• Bayer Investor Presentation • Meet Management • June 2014
Translating R&D Effectively
into Sales
From to
€
Page 150
Pipeline Peak Sales Potential  €4bn
from Products Launched 2011 - 2016*
• Bayer Investor Presentation • Meet Management • June 2014
Crop Protection
Life Cycle Management
Seeds
Cotton
Canola
Wheat
Soybean
Rice
2013
~110 launches in vegetables &
broad acre crops
Roundup Ready
Hybrid
Canola
Fungicide
Serenade Optimum
Bayer Oilseed
Mustard
Hybrids
Seed Varieties
2014
Canola Yield
Increase
Numerous launches in
vegetables & broad acre crops
Verango / Velum
Insecticide
Insect Resistant
Hybrid Rice
TwinLink +
GlyTol Cotton
Seed Varieties
20162015
*estimated and subject to regulatory approval
2 joint project with MS Technologies
Constant Life Cycle Management through new formulations and mixtures that also includes Biologicals
Disease Resistant
+ Salinity Tolerant
Hybrid Rice
Insect + Disease
Resistant
Hybrid Rice
Improved Canola
Oil Profile
Dual Herbicide Tol.
+ Novel Insect
Resistant Cotton
Insecticide
Biologicals
Seed Varieties
Numerous launches in
vegetables & broad acre crops
GlyTol + HPPD
Tolerant
Soybeans2
Biologicals
Fungicide
Bayer
Wheat Seed
LibertyLink +
Roudup Ready
Hybrid Canola
Council
Herbicide
Disease Resistant +
Submergence Tol.
Hybrid Rice
Seed Varieties
Numerous launches in
vegetables & broad acre crops
Sivanto
Insecticide
Page 151
Sivanto – Innovative and User-friendly
Insecticide Against Sucking Pests
 Active ingredient: flupyradifurone (novel insecticide class butenolides)
 Control of sucking pests such as aphids, hoppers and whiteflies
 Intended for use in fruits, vegetables, and broad acre crops
 Favorable safety profile
 Launch planned 2015*
• Bayer Investor Presentation • Meet Management • June 2014
* first registrations for foliar application; SeedGrowth use
planned to follow subsequentlyPage 152
Biological Crop Protection for Mite Control
 Mites can significantly reduce
yields and quality
 Leading to rejection of produce
along the value chain and
lower sales
 Microbial acaricide with new
mode of action
 Season-long effectiveness:
curative, eradicant, protective
 Registration expected in the U.S.
in 2016*
• Bayer Investor Presentation • Meet Management • June 2014
* subject to regulatory approval
Two-spotted spider mite under scanning electron microscope (SEM)
Page 153
Build up a Global Wheat Seed Business
 Largest broad-acre crop worldwide
 Market value still small, but major potential seen with productivity improvement
 Hybrids provide opportunity for both yield increase and improved yield stability
• Bayer Investor Presentation • Meet Management • June 2014
The Market* Our Efforts Our Goals
• 7 breeding centers
• Numerous collaborations
• Significant R&D investments
The Market
• 226m ha of wheat acres,
majority is farm-saved seed
• Current market of €0.2bn
(royalties only)
• Slow productivity increase
• Yield increase
• Nitrogen use efficiency
• Water use efficiency
• Heat tolerance
Market Entry
• Launch of first variety
planned in 2015
• Suitable for western and
central regions of the Ukraine
• Open pollinated variety
* Source: FAO, Context Networks 2012 (seed co level)
Corn: 60.7 EUR/ha  Wheat: 0.9 EUR/ha
The Market
Page 154
Acquisitions in Latin America Broaden
our Portfolio in Soybean Seed
 Building up proprietary seed
business with high quality germ-
plasm pool
 Establishing best-in-class
breeding platform
 Leveraging the potential of our trait
platform through out-licensing
 Launch of Bayer soybean brand
Credenz planned late 2014
 Integrated business model
combining seeds & crop protection
• Bayer Investor Presentation • Meet Management • June 2014
* subject to clearance by Antitrust Authority in Argentina
2013 FN Semillas*
soybean seed
company
Buenos Aires, Argentina
2011 Soytech
soybean seed
company
Goiânia, Goiás
2013 Wehrtec
soybean seed
company
Cristalina, Goiás
2013 Agropastoril
soybean germplasm
bank
Cascaval, Paraná
2010 CVR
plant breeding
Rio Verde, Goiás
Page 155
Strategic Progress Achieved
Enhance
Crop Protection
& Env. Science
Strengthen
Customer
Centricity
Lead the Way
in Innovation
Expand Seeds
Business
● €1.5bn sales in 2013 with products launched since 2006
● Biologicals strengthened further with Prophyta and Biagro*
● Expansion of supply capacities for key active ingredients
● Support to increase productivity of small-scale farmers
● Improved channel management practices
● Broadened food chain partnership business model
● Pipeline Peak Sales Potential**  €4bn
● Increased investment in Seeds R&D
● Innovating at the interface between chemistry and biology
● Strengthened presence in Latin American soybean market
● Further investments done in wheat and vegetables
● Development of innovative traits
• Bayer Investor Presentation • Meet Management • June 2014
* Clearance by Antitrust Authority in Argentina outstanding
** from products launched between 2011-2016Page 156
• Bayer Investor Presentation • Meet Management • June 2014
2013 Sales CAGR 2016e
Further Growth at Benchmark
Profitability
Page 157
Global Trends in Agriculture
• Bayer Investor Presentation • Meet Management • June 2014
GLOBAL FOOD
PRODUCTION
CLIMATE CHANGE
-322 kg rice per hectare
Yields under pressure
+1°C
FARMLAND PER CAPITA (ha)
1950 : 0.52
2010 : 0.20
2050 : 0.15
INSUFFICIENT STORAGE
Up to 40% of fruit
and vegetables
lost in India
Equivalent to the annual
consumption in UK
CHANGING CONSUMPTION
PATTERNS
Increasing demand for protein
Need for a sustainable
productivity increase
By 2050
+70%
HUNGER
1 in 8 goes hungry today
POPULATION GROWTH
7 billion people
on the planet today
9.6 billion people in 2050
Page 158
Crop Commodity Prices Declined in 2013,
But Are Still At Relatively High Levels
• Bayer Investor Presentation • Meet Management • June 2014
Source: Bloomberg
0
500
1,000
1,500
2,000
2,500
3,000
3,500
4,000
4,500
5,000
0
100
200
300
400
500
600
700
800
900
1,000
2008 2009 2010 2011 2012 2013 2014
Soybeans
(LS)
Corn (LS)
Wheat
(LS)
Canola
(LS)
Rice (RS)
Cotton
(RS)
USD/ton USD/ton
Page 159
Seed and Crop Protection Market Expected
to Grow  5% in 2014
• Bayer Investor Presentation • Meet Management • June 2014
 In many growing regions farmer income level is healthy after 3 good years
 Commodity prices still above critical threshold for farmers, triggering
investment in high-value seeds and crop protection
 Steady expansion of soybean farming in Latin America
 Expansion of agricultural production in Asia/Pacific continues
DESPITE
 Prices for agricultural commodities expected to be below 2013 levels
 Global stocks-to-use ratios for key crop commodities on upward trend
Page 160
Promising 2014 Outlook
 We expect to grow faster than the market
 We plan to raise sales by a mid- to high-single-digit percentage on a
currency- and portfolio-adjusted basis
We anticipate negative currency effects of about 3%
 We plan to increase EBITDA before special items by a low single-digit
percentage, allowing for negative currency effects of approx. €150m
• Bayer Investor Presentation • Meet Management • June 2014
Outlook depends on specific planning assumptions as detailed in the Annual Report
Assuming average FX rates of Q4‘13 (USD 1.36)Page 161
CropScience – Above Market Growth at
Benchmark Profitability
2013
Guidance
2014
Aspiration
2016
Sales Increase €8.8bn Mid- to high-single-digit %
(neg. FX effect approx. -3%)
6% CAGR
Adj. EBITDA Increase €2.2bn Low-single-digit %
(neg. FX effect approx. -€150m)
Adj. EBITDA Margin 25.5% - 24-25%
Assuming average FX rates of Q4‘13 (USD 1.36)
Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales
• Bayer Investor Presentation • Meet Management • June 2014Page 162
 Increasing demand for innovative and
sustainable agricultural solutions
 Expansion of production capacity of
for herbicide glufosinate-ammonium
 Broadening seeds infrastructure for
soybean and wheat
 Expanding and modernizing R&D
facilities
 CAPEX expansion to
€2.4bn for 2013 - 2016
Stepping Up Investment Plans to Fuel
Future Growth
• Bayer Investor Presentation • Meet Management • June 2014
Capital Expenditures (PPE only, in €m)
303
453
620
2012 2013 2014e
Page 163
Investor Handout – Meet Management
Bayer MaterialScience
June 2014 – New York
MaterialScience –
Leading Positions in All Segments
• Bayer Investor Presentation • Meet Management • June 2014
* Aliphatic isocyanates
MaterialScience €11,238m
Polyurethanes
€6,054m
 #1-2; approx. 19-24% market share
54% 6%
23%
17%
Sales in € million
Polycarbonates
€2,640m
 #1; approx. 27% market share
Coatings, Adhesives, Specialties
€1,863m
 #1; >40% market share*
Industrial Operations
€681m
Sales Split by Segment 2013
Page 165
MaterialScience –
Global Production Network
• Bayer Investor Presentation • Meet Management • June 2014Page 166
*Market share based on estimated sales following self-assessment
# Europe, Middle East & Africa
Headquarters
Major Production Sites
Downstream Businesses
Position*
Americas
# 1 # 2 # 1
PUR PCS CAS
Position*
EMEA#
# 1 # 1 # 1
PUR PCS CAS
Position*
Asia/Pacific
# 2-3 # 1-2 # 1
PUR PCS CAS
• Bayer Investor Presentation • Meet Management • June 2014Page 167
Automotive
Other industries*
Construction Furniture / Wood Electro / Electronics
19% 18% 15%21%
MaterialScience –
Sales By Key Customer Industries
Bayer MaterialScience sales by industry in 2013
= 73% +
Chemicals
*Sports/leisure, cosmetics, health
10% 17%
MaterialScience as an Integrated Solution
Provider
• Bayer Investor Presentation • Meet Management • June 2014Page 168
Megatrends offer business opportunities worldwide, with the emerging
economies at the forefront
Ongoing
urbanization
New and
improved
transportation
systems
Need for
better
energy
efficiency
Higher
living
standards
Proportion of city
dwellers expected to
increase from 50%
in 2010 to 70% in
2050*
Lightweight cars
New energy vehicle
development
High-speed rail trans-
portation networks
EcoConstruction with
high thermal insulation
standards
Cold-chain efficiency
Over 40m people
enter the middle class
every year
Improved housing
standards
Source: Steria, The Future Report 2012
• Bayer Investor Presentation • Meet Management • June 2014Page 169
Performance Below
Expectations
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Meet management 2014-06-05_ny_investor_handout_web_slideshare

  • 1. Meet Management Conference New York, June 5, 2014 Marijn Dekkers, CEO Bayer
  • 2. Disclaimer This presentation may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments. • Bayer Investor Presentation • Meet Management • June 2014Page 2
  • 3. Page 1 Our Mission – Innovation and Customer Value  Bayer is an innovation company  With a strong “innovation portfolio”  Addressing new growth areas  Capable of identifying and using breakthrough innovations  Bayer is innovative in many ways: Products, technologies, processes, business models, strategies  Bayer products improve the quality of people’s lives  Bayer has an excellent understanding of human, animal and plant health, as well as of high-quality materials  Respect for people and nature is an essential part of our values Science / Innovation Better Life Science For A Better Life • Bayer Investor Presentation • Meet Management • June 2014
  • 4. Page 2 Our Business Portfolio – Leading in Its Markets Break-down excluding reconciliation Sales 2013: €40.2bn CropScience Chemical crop protection & biologicals global #2, seeds & traits €8.8bn MaterialScience Polyurethanes and polycarbonates, global #1/2 €11.2bn HealthCare Pharmaceuticals €11.2bn, leading positions in core indications Consumer Health €7.7bn, OTC #2, blood glucose meters #3, Animal Health #5, contrast media #1 €18.9bn 23% 29% 48% • Bayer Investor Presentation • Meet Management • June 2014
  • 5. We Generate Almost 90 Percent of our Earnings in the Life Sciences Businesses Page 3 *EBITDA before special items 23% 29% 45% 88% 12% Sales 2013 Adj. EBITDA 2013* Human Health 3% Breakdown excluding Reconciliation Material Science Plant Health Animal Health Life Sciences Material Science • Bayer Investor Presentation • Meet Management • June 2014
  • 6. • Bayer Investor Presentation • Meet Management • June 2014Page 4 2010-2013 – A Period of Significant Success  Delivered growth and performance  Unprecedented R&D productivity  Pharma launch product sales ahead of expectations  Executing successfully our OTC growth strategy  CropScience customer-centric strategy bearing fruit  Capital discipline at MaterialScience
  • 7. 2010-2013 – A Period of Significant Progress Page 5 2010 2011 2012 2013 35.1 36.5 39.7 40.2 7.1 7.6 8.3 8.4 Sales 5% Core EPS 10% Adj. EBITDA 6% 4.19 4.83 5.30 5.61 Sales and adjusted EBITDA in € billion, core EPS in € CAGR 2010-2013 • Bayer Investor Presentation • Meet Management • June 2014
  • 8. Page 6 EBIT in € million +18% 2,096 1,771 Sales in € million % currency & portfolio adj. +8% 10,55510,266 EBITDA adjusted* in € million +12% 2,738 2,453 Core EPS in € +15% 1.95 1.70 *before special items Q1’14Q1’13 Q1’14Q1’13 Q1’14Q1’13 Q1’14Q1’13 Strong Momentum Continued in Q1 2014 Despite Significant Currency Headwind • Bayer Investor Presentation • Meet Management • June 2014
  • 9. FY 2014 Group Guidance Maintained – Targeting Further Sales and Earnings Growth Page 7 2013 2014E* Sales €40.2bn ~5% to ~€41-42bn (neg. FX effect approx. -2%) adj. EBITDA €8.4bn low- to mid-single- digit % increase (neg. FX effect approx. -5%) core EPS €5.61 mid-single-digit % increase (neg. FX effect approx. -6%) Sales ∆ Fx and portfolio adjusted, EBITDA before special items *Assuming average Fx rates of Q4’13 (USD 1.36) Outlook depends on specific planning assumptions as detailed in the Annual Report• Bayer Investor Presentation • Meet Management • June 2014
  • 10. Page 8 2013 Sales CAGR 2016e Pharma: Maximize Value of Launch Products • Bayer Investor Presentation • Meet Management • June 2014
  • 11. 24 Successful Phase III Clinical Trials at Pharma since 2010 Page 9  Various indications incl. treatment of deep vein thrombosis/pulmonary embolism, stroke prevention in atrial fibrillation and secondary prevention of acute coronary syndrome  Wet age-related macular degeneration, diabetic macular edema, myopic choroidal neovascularization and central retinal vein occlusion  Metastatic colorectal cancer and metastatic gastrointestinal stromal tumors  Metastatic castration-resistant prostate cancer with symptomatic bone metastases  Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension  Radioactive iodine refractory differentiated thyroid cancer  Prophylaxis in hemophilia A: Site-specific PEGylated Factor VIII with 5- or 7-days dosing intervals • Bayer Investor Presentation • Meet Management • June 2014 BAY 94-9027 Major examples
  • 12. Launch Products Drive Growth at Pharma • Bayer Investor Presentation • Meet Management • June 2014Page 10 Sales in € billion; ∆% Fx & portf. adjusted Pharma Sales / Launch Products Launch Products 2013 2010 2011 2012 2013 10.0 1.5 25% 949 197 333 3 41 Sales in € million 9.9 10.8 11.2 +1% +4% +9%
  • 13. Launch Products Expected to Contribute ~€2.8bn to Pharma Sales in 2014 • Bayer Investor Presentation • Meet Management • June 2014  Executing >100 launch events* in 2014  Continuous R&D investments in life-cycle management  Increased marketing and sales investments in emerging markets  Incremental marketing and R&D investments of €0.5bn in 2014e * new indications and new countries Page 11
  • 14. Page 12 Pharma – Peak Sales Potential of Launch Products was Raised in February to ≥€7.5bn  Continued successful launch exe- cution and life cycle management  Unchanged  Unchanged  Unchanged ~€3.5bn ≥€1.5bn ≥€1bn ≥€1bn ≥€0.5bn >€2bn ≥€1bn Old Current • Bayer Investor Presentation • Meet Management • June 2014  Continued successful launch exe- cution and life cycle management
  • 15. Two Recent Steps Forward for Bayer’s Pharma Business • Bayer Investor Presentation • Meet Management • June 2014 Acquisition of Algeta Strategic Pharma sGC Collaboration with Merck  Full control over Xofigo  Comprehensive life-cycle management program, including studies in earlier settings of prostate cancer, combination studies and other tumors  Complementing Bayer’s sGC franchise, including Adempas, with Merck’s cardiovascular capabilities  Leverage joint development capability to fully explore broad potential of sGCs  Building Bayer’s US presence in specialty pharma while leveraging Merck’s US strength Page 13
  • 16. Pharma – Maximizing the Value of Launch Products Page 14 2013 Guidance 2014 Aspiration 2016 Sales Increase €11.2bn High-single digit % (neg. FX effect approx. -2%) 8% CAGR Adj. EBITDA Increase €3.5bn Low- to mid-single digit % (neg. FX effect approx. -€150m) Adj. EBITDA Margin 31.2% Level with prior year ≥33% Assuming average FX rates of Q4‘13 (USD 1.36) Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales • Bayer Investor Presentation • Meet Management • June 2014
  • 17. • Bayer Investor Presentation • Meet Management • June 2014Page 15 Aspire to Become the Leading OTC Company
  • 18. • Bayer Investor Presentation • Meet Management • June 2014Page 16  Portfolio of some of the world’s most recognized brands  Outperforming market growth in past 7 out of 8 years  Successful expansion in EM focus markets, China, Brazil, and Russia  Selected bolt-on acquisitions in key countries: Steigerwald, Germany & Dihon, China  Acquisition of Merck’s Consumer Care business – a major step towards OTC leadership 3.4 3.5 3.9 3.9 2010 2011 2012 2013 +5% +7% +6% Consumer Care sales in € billion; ∆% Fx & portfolio adj. *planned acquisition, closing expected in H2 2014 Successfully Executing OTC Growth Strategy
  • 19. • Bayer Investor Presentation • Meet Management • June 2014Page 17 Acquisition of Merck’s Consumer Care Business Makes us #2 Globally and #1 in US Highlights $14.2bn investment, all cash, fully debt financed Complementary portfolio offering scale in key categories and optimized geographic footprint Full trademark ownership for Claritin Market Positioning 2013* *Pro-forma OTC sales 2013; after allowing for the Novartis/Glaxo deal and Bayer/Merck transaction; CC: Consumer Care in € billion
  • 20. Combination Offers Significant Synergy Potential • Bayer Investor Presentation • Meet Management • June 2014Page 18 Cost synergies of ~$200m p.a. by 2017 Tax benefits from year 1  Asset purchase with significant future tax savings  Savings in marketing costs  Savings in COGS, administration Step-up of EBITDA margin pre-special items at Consumer Care by ~1pp and core EPS accretion of 2% already in the first year Revenue synergies of already ~$400m by 2017  Incremental US sales  Realize brand penetration opportunities ex-US Revenue Cost Tax
  • 21. Page 19 • Bayer Investor Presentation • Meet Management • June 2014 2013 Sales CAGR 2016e CropScience: Further Growth at Benchmark Profitability
  • 22. Delivering Growth And Performance at CropScience 6.8 7.3 8.4 8.8 2010 2011 2012 2013  2013 – the 3rd year in a row delivering strong sales growth at record margin  New product sales 2013 up 33% at €1.5bn*  Strong start to 2014 season with sales up 12% Sales in € billion, ∆% Fx & portf. adjusted, Adj. EBITDA margin in % 19.0 24.2 25.5 22.8 +9% +12% Page 20 • Bayer Investor Presentation • Meet Management • June 2014 Customer-centric strategy bearing fruit *Sales with Crop Protection products launched since 2006 +9%
  • 23. Significant Contribution from New Crop Protection Products • Bayer Investor Presentation • Meet Management • June 2014Page 21 *Sales with Crop Protection products launched since 2006 1.1 1.5 1.8 2.6 2012 2013 2014e 2016e +33% Sales from new Crop Protection products launched since 2006 in €bn ∆% y-o-y, () Fx adj. Q1 0.6  (+16%) - Superior ‘all-in-one’ cereal fungicide with yield-boosting effect  herbicide (+14%) - Excellent weed control in corn and cereals, also in case of glyphosate resistance  (+75%) - Broad-spectrum insecticide with fast, long-lasting action  (+112%) - New fungicide now available in several key markets Q1 2014 Highlights
  • 24. Significant Investments in our Growth Platforms • Bayer Investor Presentation • Meet Management • June 2014Page 22 BiologicalsSeeds  >€300m R&D investments p.a. to support leadership positions in cotton & oilseed and to develop position in soybean and wheat  Further selected acquisitions to strengthen portfolio and regional setup, esp. in Latin America  Launch of first soybean brand Credenz (2014e)  Launch of first wheat variety (2015e)  Successful market entry with nematode seed treatment Poncho/Votivo (sales 2013: ~€150m)  Acquisition of AgraQuest, global provider of innovative biological pest management solutions  Acquisition of Prophyta, a provider of well-established products, e.g. nematicide BioAct  Acquisition of Biagro* adds nitrogen inoculants & plant health promoters *Subject to regulatory approvals
  • 25. CropScience – Above Market Growth at Benchmark Profitability Page 23 2013 Guidance 2014 Aspiration 2016 Sales Increase €8.8bn Mid- to high-single-digit % (neg. FX effect approx. -3%) 6% CAGR Adj. EBITDA Increase €2.2bn Low-single-digit % (neg. FX effect approx. -€150m) Adj. EBITDA Margin 25.5% - 24-25% Assuming average FX rates of Q4‘13 (USD 1.36) Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales • Bayer Investor Presentation • Meet Management • June 2014
  • 26. • Bayer Investor Presentation • Meet Management • June 2014Page 24 MaterialScience: Improve Returns
  • 27. • Bayer Investor Presentation • Meet Management • June 2014Page 25 Macro-Economic Environment for MaterialScience Likely to Improve  Oil price expected to stabilize in 2014 (budget of Ø $110 per bbl*)  Supply & demand balances of key products improving with:  Long-term demand drivers intact  Limited net new capacity to come on stream 21% 18% 27% 19% Automotive (+4%) Electro / Electronic (+6%) Construction (+4%) Furniture (+4%) Others (incl. Chemicals) 15% Sales by industry 2013 and expected 2014 growth Key Customer Industries Outlook Additional Key Performance Drivers *Ø 2013: $110 per bbl
  • 28. • Bayer Investor Presentation • Meet Management • June 2014Page 26 Q1 2014 – MaterialScience: Demand Led Growth Sales Earnings **CAS: Coatings, Adhesives, Specialties; *** IO: Industrial Operations CAS** 0% (+7%) In € million, ∆% yoy, () = Fx & portf. adjusted *before special items; MaterialScience €2,803m; +1% (+5%) Price -3% Volume +8% Fx -3% Portfolio -1% 1,510659 IO*** -6% (-5%) Q1‘13 Q1‘14 Q1‘13 Q1‘14 Adj. EBITDA* Adj. EBIT* 204 366 +79% 43 221 469 165 Polyurethanes +3% (+6%) Polycarbonates -1% (+2%) >100%
  • 29. MaterialScience – Asset Utilization and Efficiency Measures to Drive Cash Returns • Bayer Investor Presentation • Meet Management • June 2014Page 27 2013 Guidance 2014 Aspiration 2016 Sales Increase €11.2bn Mid-single-digit % (neg. FX effect approx. -2%) Volume growth > global GDP Adj. EBITDA Increase €1.1bn Increase (neg. FX effect approx. -€50m) - CFROI vs. WACC 5.5% < 6.9% - CFROI > WACC Assuming average FX rates of Q4‘13 (USD 1.36) Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales
  • 30. Bayer – Optimistic About Future Developments Peak sales potential of new pharma products of ≥€7.5bn Track record of performance: Core EPS with 10% CAGR since 2010 Successful start to 2014 – full-year 2014 group guidance maintained Page 28 Successfully executing on OTC growth strategy • Bayer Investor Presentation • Meet Management • June 2014
  • 31. Page 29 Appendix • Bayer Investor Presentation • Meet Management • June 2014
  • 32. EBIT in € million +26% 4,934 3,928 Sales in € million % currency & portfolio adj. +5% 40,15739,741 EBITDA adjusted* in € million +1% 8,4018,280 Core EPS in € +6% 5.61 5.30 *before special items FY’13FY’12 FY’13FY’12 FY’13FY’12 FY’13FY’12 FY 2013 – Encouraging Performance Driven by Life Sciences Page 30 • Bayer Investor Presentation • Meet Management • June 2014
  • 33. FY 2013 – Regional Performance Page 31 Africa & Middle East Eastern Europe Emerging Economies Emerging Economies¹ +7% Others² +10% USA +4% Western Europe +2% 2013 Group Sales by Region Group €40,157m; +5% ~5,100 +15%~5,800 +4% ~1,700 -1%~2,500 +7% 1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe 2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand In € million, ∆% yoy Fx adjusted 38% 10% 31% 21% Latin America Emerging Asia³ • Bayer Investor Presentation • Meet Management • June 2014
  • 34. FY 2013 – HealthCare Page 32 *before special items 2013 Sales Earnings Pharma +4% (+9%) Consumer Health -1% (+3%) 36% HealthCare €18,924m; +2% (+7%) 11,1887,736 Price +1% Volume +6% Fx -6% Portfolio +1% In € million, ∆% yoy, () = Fx & portf. adjusted FY‘12 FY‘13 FY‘12 FY‘13 3,232 3,490 1,887 1,844 +8% -2% 5,119 5,334 +4% 1,460 -3% 3,787 3,973 +5% 2,327 1,421 Adj. EBITDA* Adj. EBIT* 2,552 +10% • Bayer Investor Presentation • Meet Management • June 2014
  • 35. FY 2013 – CropScience Page 33 Crop Protection +7% (+11%) Environmental Science -4% (+1%) *before special items Seeds +1% (+1%) 2013 Sales Earnings In € million, ∆% yoy, () = Fx & portf. adjusted CropScience €8,819m; +5% (+9%) Price +3% Volume +7% Fx -5% Portfolio +1% 7,194 FY‘12 FY‘13 FY‘12 FY‘13 2,025 2,248 +11% 1,543 1,801 +17% Adj. EBITDA* Adj. EBIT* 651 974 • Bayer Investor Presentation • Meet Management • June 2014
  • 36. FY 2013 – MaterialScience Page 34 2013 Sales Earnings In € million, ∆% yoy, () = Fx & portf. adjusted MaterialScience €11,238m; -2% (0%) Price 0% Volume +1% Fx -2% Portfolio 0% 6,054 FY‘12 FY‘13 FY‘12 FY‘13 Adj. EBITDA* Adj. EBIT* 1,263 1,072 -15% 613 429 -30% Polycarbonates -6% (-5%) CAS** -6% (-2%) 2,640 IO*** -4% (-4%) 1,863 681 Polyurethanes +1% (+4%) **CAS: Coatings, Adhesives, Specialties; *** IO: Industrial Operations *before special items; • Bayer Investor Presentation • Meet Management • June 2014
  • 37. FY 2013 – Cash Flow And Net Debt Development Page 35 -€0.3bn 6.7 GCF oFCF 5,832 Invest- ments 2,157 3,014 ∆ y-o-y +28% +16% NCF 5,171 +14% +12% Dec 31, 2012 Dec 31, 2013 7.0 FY 2013 Cash Flow Net Debt Development Cash Flow in € million, Net Debt in € billion • Bayer Investor Presentation • Meet Management • June 2014
  • 38. On Our Way to OTC Leadership Investor Handout – Meet Management Acquisition of Merck & Co.’s Consumer Care Business June 2014 – New York
  • 39. Evolution of Bayer Consumer Care’s OTC Business 2008 Acquisition of OTC brand portfolio from Sagmel (CEE) and Topsun (China) 1999 Aspirin trademark centenary-worldwide sales > €500m 1899 ASPIRIN introduced as an over-the-counter (OTC) medicine 1994 Consumer Care business group created by the acquisition of North American OTC business of Sterling; Acquisition of the “Bayer Cross” Trademark in USA 2005 Acquisition of Roche Consumer Health 2013 Aspirin trademark sales of >€900m Acquisition of Steigerwald (Germany) Page 37 • Bayer Investor Presentation • Meet Management • June 2014 2014 Proposed acquisition of Merck’s Consumer Care business (US) Transaction agreement signed with Dihon Pharmaceutical Group (China)
  • 40. • Bayer Investor Presentation • Meet Management • June 2014Page 38 Growth Strategy  Maximize brand potential  Global expansion of key brands  Exploit our innovation pipeline  Grow in emerging markets  Increase commercial power  Bolt-on acquisitions to strengthen portfolio & regional set-up 3.4 3.5 3.9 3.9 2010 2011 2012 2013 +5% +7% +6% Consumer Care sales in € billion; ∆% Fx & portfolio adj. Bayer Consumer Care – Outperforming Markets in Past 7 Out of 8 Years
  • 41. Merck’s Consumer Care Business Fits Perfectly With Bayer Consumer Care • Bayer Investor Presentation • Meet Management • June 2014 Complementary Portfolio Building on core competencies  Creation of a global leader in OTC  Gaining scale in key categories CASF1, dermatology, and gastrointestinal  Optimizing footprint in North America  Strong track record of growing OTC brands  Strong geographical presence to broaden Merck’s portfolio globally  Utilizing integration skills from past transactions Page 39 Acquisition criteria fulfilled  Creating leadership positions in important consumer care categories and geographies  Increasing consumer care margin2 by ~1pp from year 1  Immediate core EPS accretion from year 13 1 cold, allergy, sinus, flu; 2 EBITDA pre-special items; 3 transaction incl. sGC collaboration
  • 42. Page 40 • Bayer Investor Presentation • Meet Management • June 2014 Combined Portfolio Significantly Strengthens Global Positions Gastrointestinal Analgesics3 CASF2 Nutritionals Dermatology1 Total Others4 3,904 1,635 5,539 1,110 386 372 803 126 513 439 141 1,023 834 1 including sun care; 2 Cold, Allergy, Sinus, Flu; 3 including Cardio; 4 Foot Health, Women’s Health, Other 1,496 1,023 1,175 834 580 431 #1 #2 #3 #1 #2 Global position*2013 Sales in €m (pro-forma portfolio) Note: Merck sales converted at average USD rate of 1.33 (FY 2013) 305 *After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx MerckBayer
  • 43. Page 41 • Bayer Investor Presentation • Meet Management • June 2014 Combined Portfolio Significantly Strengthens Geographic Footprint Note: Merck sales converted at average USD rate of 1.33 (FY 2013) *After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx Latin America Europe North America Total Asia/Pacific 3,904 1,635 5,539 1,117 1,105 1,621 170 389 513 141 777 2,222 1,791 946 580 #1 #1 #5 #2 Global position*2013 Sales in €m (pro-forma portfolio) 191 169 MerckBayer
  • 44. FY 2013 sales in € million (∆% yoy Fx-adj.) 321 310 232 214** 207 176 158 257 *Total Aspirin includes Aspirin Complex and Aspirin Cardio (Rx) **Total Alka-Seltzer includes Alka-Seltzer and Alka-Seltzer Plus 916* = Rx Sales Page 42 • Bayer Investor Presentation • Meet Management • June 2014 Combined Top 10 Portfolio – Individual Brands with Annual Sales >€100m 576 Note: Merck sales converted at average USD rate of 1.33 (FY 2013); based on pro-forma FY 2013 net sales
  • 45. • Bayer Investor Presentation • Meet Management • June 2014Page 43 Top Priorities To Be Executed Immediately After Closing of Transaction…  Ensure fast integration into operations  Safeguard product supply  Realize synergy potential  Prioritize brand strategies within combined portfolio  Realize Merck brand penetration opportunities ex-US  Define and execute individual brand strategies  Develop US scale advantage  Strive for leadership with trade customers  Provide a broader product portfolio Critical mass in US Brand Roll- Out ex-US Smooth integration
  • 46. • Bayer Investor Presentation • Meet Management • June 2014Page 44 Clear Strategy For a Smooth Integration 2014 Q2 2014 Q42014 Q3 2015 (End State)  Smooth integration expected due to experienced management team • Ensure effective integration into Consumer Care • Safeguard on-going product supply • Prioritize and execute identified brand development / expansion strategies • Ensure sufficient future capacity for growth • Capitalize on Merck’s innovation capabilities • Achieve scale and revenue synergies • Capture consolidation and efficiency synergies by 2017  Deal signing  Deal closing  Consolidation / Integration
  • 47. • Bayer Investor Presentation • Meet Management • June 2014Page 45 Enhanced Scale and Broader Category Scope Improve Product Offerings US Retail Sales CASF Benefits from Enhanced Scale  Co-promoting complementary brands  New item assortment and shelving opportunities  Improved merchandising efficiencies  Bigger and more impactful trade events  Foster strategic partnerships with retailers FY 2013 retail sales in CASF in $ million* $- $200 $400 $600 $800 $1,000 $1,200 RB Bayer & Merck J&J Merck & Co. P&G Pfizer Chattem Bayer GSK *Source: IRI; Latest 52WK; December 2013  Make Bayer Consumer Care Top Strategic Partner for US Retailers
  • 48. Maximizing Brand Potential Through Global Expansion Brand Sales by Major Region 2013 Expansion Plans • Bayer Investor Presentation • Meet Management • June 2014Page 46 Analgesic ~80% in North America ~95% in North America Wound-healing ~75% in Europe Anti-fungal ~75% in Europe & LatAm Vitamins & minerals ~50% in Europe ~80% in North America CASF Sun Care
  • 49. • Bayer Investor Presentation • Meet Management • June 2014Page 47 Russia Country OTC Market Sales Growth 2013* Execution Plans China  Global #2  Growing 2x the global rate  Use investments in footprint, brand-building and sales capabilities to extend Claritin leadership  Build sun care category with Coppertone Brazil  Global #7  Fastest growing market in LATAM  Use investments in brand-building and channel capabilities to develop key new categories (sun care, foot care, allergy)  Revitalize Coppertone and Dr. Scholl’s brands Russia  Global #4  Retail OTC is largest healthcare segment  Focus on CASF brands using current position to roll-out extended offerings  Achieve #2 position Execution Plan Focused on Key Brands in Key Emerging Markets +38% +26% +14% *Bayer Consumer Care sales, currency-adjusted
  • 50. Consumer Care is Well-Positioned for Growth – Aspire to Clear OTC Leadership OTC Market Attractive Bayer Has Strong #2 Position Plans for Continued Future Growth  Trends favor continued growth  OTC market model based on long-term brand building  OTC businesses becoming more valuable over time  Leader in key categories  Multiple strong brands  Track record of outperforming market growth  Globalize established brands & launch innovation pipeline  Focus on emerging markets where most of growth will come  Strategic acquisitions and alliances Page 48 • Bayer Investor Presentation • Meet Management • June 2014
  • 51. Investor Handout – Meet Management Bayer HealthCare June 2014 – New York
  • 52. Leading Positions in Key Healthcare Markets • Bayer Investor Presentation • Meet Management • June 2014 Pharma €11,188m  Leading positions in key therapeutic categories Consumer Care €3,904m  Global #2 in OTC-pharmaceuticals Medical Care €2,526m  #1 in fluid injection systems, #1 in contrast media, #3 in blood glucose meters Animal Health €1,306m  Global #5, #2 in parasiticides Sales Split by Segment 2013 25% 59% 7% 21% 13% HealthCare €18,924m Page 50
  • 53. FY 2013 – Growth Mainly Pharma Driven • Bayer Investor Presentation • Meet Management • June 2014 *before special items FY 2013 HealthCare Sales Earnings Pharma +4% (+9%) Consumer Health -1% (+3%) 36% 11,1887,736 In € million, ∆% yoy, () = Fx & portf. adjusted FY 12 FY 13 FY 12 FY 13 3,232 3,490 1,887 1,844 +8% -2% 5,119 5,334 +4% 1,460 -3% 3,787 3,973 +5% 2,327 1,421 Adj. EBITDA* Adj. EBIT* 2,552 +10% HealthCare €18,924m; +2% (+7%) Price +1% Volume +6% Fx -6% Portfolio +1% Page 51
  • 54. FY 2013 – Top 10 HealthCare Product Performance • Bayer Investor Presentation • Meet Management • June 2014 MI: Myocardial infarction Sales in € million; ∆% y-o-y Fx adjusted +6% -12% -1% +3% +2% +10% -1% +2% +211% 1,202 1,038 916 771 949 719 853 722 603 487 Hemophilia A Multiple Sclerosis Anticoagulation Contraception Cancer Blood Glucose Meter Contraception Analgetic & sec. MI Prevention Parasiticide -13% Hypertension Page 52
  • 55. FY 2013 – Strong Business Momentum in All Regions, Especially Emerging Markets • Bayer Investor Presentation • Meet Management • June 2014 Emerging Economies 25% FY 2013 HealthCare Sales Latin America Eastern Europe Africa & Middle East ~2,190 +7% ~1,980 +10% ~1,140 ~880 +4% 24% USA +5% 30% 33% 13% Sales in € million; ∆% y-o-y Fx adjusted Emerging Economies¹ +8% Emerging Asia³ Western Europe +6% Others² +12% HealthCare €18,924m; +2% (+7%) Page 53 +10% 1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe 2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand
  • 56. • Bayer Investor Presentation • Meet Management • June 2014 Recently Launched Pharma Products Drive Growth Page 54
  • 57. Q1 2014 – HealthCare: Recently Launched Products Drive Growth Page 55 *before special items Sales Earnings Pharma +9% (+15%) Consumer Health -5% (+1%) 36% HealthCare €4,572m; +3% (+9%) 2,7821,790 Price 0% Volume +9% Fx -7% Portfolio +1% In € million, ∆% yoy, () = Fx & portf. adjusted Q1‘13 Q1‘14 Q1‘13 Q1‘14 832 873 445 428 +5% -4% 1,277 1,301 +2% 343 -6% 953 946 -1% 610 321 Adj. EBITDA* Adj. EBIT* 625 +2% • Bayer Investor Presentation • Meet Management • June 2014
  • 58. Q1 2014 – Top 10 HealthCare Product Performance • Bayer Investor Presentation • Meet Management • June 2014 MI: Myocardial infarction Sales in € million; ∆% y-o-y Fx adjusted +133% -6% +14% +12% +239% -12% -1% -22% 342 270 183 178 190 146 181 157 140 Hemophilia A Multiple Sclerosis Anticoagulation Contraception Cancer Ophthalmology Contraception Analgetic & sec. MI Prevention -3% Hypertension Page 56 Blood Glucose Meter 217 +6%
  • 59. • Bayer Investor Presentation • Meet Management • June 2014Page 57 2013 Sales CAGR 2016e Pharma: Maximize Value of Launch Products
  • 60. 2011 2012 2013 2014 Page 58 Pharma – Incremental Investments For A New Performance Level * new indications and new countries; products include Xarelto, Eylea, Stivarga, Xofigo, Adempas• Bayer Investor Presentation • Meet Management • June 2014 Launch product sales in € bn  Launch product* sales target of ~€2.8bn in 2014 (old aspiration 2015: >€2.5bn)  Launch phase to continue with >100 new launch events*  Continuous R&D investments in life- cycle management  R&D investments in new drug candidates  Increased marketing and sales investments in emerging markets  Incremental marketing and R&D investments of €0.5bn planned in 2014 <0.1 0.4 1.5 ~2.8 Stivarga Xarelto Eylea Xofigo Recently launchd Pharma products*
  • 61. Pharma – Additional Investments To Execute >100 Launch Events in 2014 • Bayer Investor Presentation • Meet Management • June 2014Page 59 1: regulatory process ongloing, launch preparations assuming approval DTC: Differentiated thyroid cancer; mCRC: Metastatic colorectal cancer ; mGIST: Metastatic gastrointestinal cancer; ACS: Acute coronary syndrome  ~ 30 launches planned in secondary prevention of ACS  Market introduction planned in >20 countries  > 30 launches planned in mGIST1 in EU and other markets; continue roll-out in mCRC (examples include Spain, Italy, Turkey)  ~ 15 launches planned, including wetAMD and additional indications (CRVO, mCNV1, DME1)  Launches1 planned in > 20 countries  > 30 launches planned in DTC1 in EU and other markets Major Examples  > 30 launches planned
  • 62. • Bayer Investor Presentation • Meet Management • June 2014 Peak Sales Potential of Launch Products Raised in February 2014 Peak Sales Potential* * from 5 recently launched products: Xarelto, Eylea, Stivarga, Xofigo, Adempas Page 60
  • 63. Page 61 Pharma – Peak Sales Potential of Launch Products Raised in February to ≥ € 7.5bn* *assuming approvals and launches as planned  Continued successful launch exe- cution and life cycle management  Continued successful launch exe- cution and life cycle management  Unchanged  Unchanged  Unchanged ~€3.5bn ≥€1.5bn ≥€1bn ≥€1bn ≥€0.5bn >€2bn ≥€1bn Old Current • Bayer Investor Presentation • Meet Management • June 2014
  • 64. Xarelto – Broadest Profile of Any Novel Oral Anticoagulant • Bayer Investor Presentation • Meet Management • June 2014 Peak sales potential ~ €3.5bn  Oral Factor Xa inhibitor  Once-daily dosing advantage*  First launches in EU for secondary prevention of ACS underway  Two-dimensional approach in life-cycle management:  Expansion into additional thromboembolic disease areas  Strengthening the clinical profile in approved indications and special patient populations *exception 15mg BID dosing for treatment of acute DVT/PE or 2.5mg BID for ACS sec. prevention; ACS: Acute coronary syndromePage 62
  • 65. • Bayer Investor Presentation • Meet Management • June 2014 Xarelto – Performance Exceeding Expectations Page 63  World-class launch, achieved leading position in the novel anticoagulants segment in key markets  Uptake significantly exceeding expectations  Sales target 2014: € 1.3-1.5bn131 155 219 259 316 342 Q4'12 Q1'13 Q2'13 Q3'13 Q4'13 Q1'14 Xarelto sales in million €
  • 66. Expanding and Strengthening the Profile of Xarelto • Bayer Investor Presentation • Meet Management • June 2014Page 64  Significant medical need in thromboembolic disease areas  Heterogeneous patient populations in existing indications deserve further characterisation  Two-dimensional approach in life-cycle management Expansion into addional thromboembolic disease areas Strenghtening the clinical profile in approved indications  Peripherial arterial disease / coronary arterial disease  Chronic heart failure with coronary arterial disease  Medically ill patients  Patients with percutaneus coronary intervention  Patients who undergo cardioversion  Patients undergoing ablation  Evaluate 10mg /20mg dose vs. ASA in secondary prevention of VTE ASA: Acetylsalicylic acid, VTE: Venous thromboembolism
  • 67. Eylea – Developed for the Treatment of Multiple Back-of-the-Eye-Diseases • Bayer Investor Presentation • Meet Management • June 2014 Peak sales potential ≥ €1.5bn  Eylea is an anti-angiogenic therapy, formulated for injection into the eye  Strong adoption by retina community in wAMD based on convenient bimonthly dosing1 regimen  Comprehensive range of indications to address major eye diseases2:  Launched in wAMD and CRVO; roll-out ongoing  Filed for DME (EU: 11/13; J: 02/14)  Filed for mCNV in Japan (11/13)  Filing planned for BRVO (in J, other regions under evaluation) 1: after an initial phase of 3 consecutive monthly injections; 2: Bayer has marketing rights ex-US; wAMD: Wet age-related macular degeneration; CRVO: Central retinal vein occlusion; BRVO: Branched retinal vein occlusion; mCNV: Myopic choroidal neovascularization; DME: Diabetic macular edema Page 65
  • 68. • Bayer Investor Presentation • Meet Management • June 2014 Eylea – Excellent Launch Trajectory Page 66  Excellent launch execution ahead of expectations  Market shares* > 45 % in Japan and Australia  Roll-out in Europe underway  Strong uptake in early launch markets Germany and Switzerland  Encouraging launch in France and UK  Positive NICE guidance for CRVO indication in UK obtained in 02/14  Progress with launch preparations for i) additional countries and ii) additional back-of-the-eye diseases** *Market share as of December 2013 (Source IMS) ** pending regulatory approval 14 49 73 85 126 157 Q4'12 Q1'13 Q2'13 Q3'13 Q4'13 Q1'14 Eylea sales in million €
  • 69. Stivarga – Developed as a Treatment for Cancers of the Digestive Tract • Bayer Investor Presentation • Meet Management • June 2014  Oral cancer drug, potently blocking multiple protein kinases  Launched for treatment of mCRC and mGIST in the US & Japan  Launched for treatment of mCRC (8/13) and filed for mGIST (9/13) in Europe  Encouraging initial uptake  Expanding to new indications  Phase III in 2nd line liver cancer ongoing  Phase III in CRC (adjuvant therapy after resection of liver metastases) ongoing mCRC: Metastatic colorectal cancer GIST: Gastrointestinal stromal tumors Peak sales potential ≥ €1bn Page 67
  • 70. Entering Additional Cancers of the Gastro-Intestinal Tract with Stivarga • Bayer Investor Presentation • Meet Management • June 2014Page 68  Positive clinical data in metastatic colorectal cancer and 2nd-line hepatocellular carcinoma  Mode of action suggesting activity in a broad range of tumor types  Life-cycle management targets:  Phase III in 2nd-line hepatocellular carcinoma  Phase III in colorectal cancer after resection of liver metastases  Signal generating early clinical studies in various cancer types including gastric cancer HCC: Hepatocellular carcinoma CRC: Colorectal cancer Expand in HCC and CRC Expand to additional tumor types
  • 71. • Bayer Investor Presentation • Meet Management • June 2014 Xofigo – A New Treatment for CRPC Patients with Bone Metastases  First in class alpha-pharmaceutical  Treatment of CRPC with symptomatic bone metastases and no known visceral metastatic disease  Launched in the US (06/13)  Approved in Europe (11/13) – launch underway  High awareness among oncologists and urologists  Life-cycle program initiated (including combination studies in earlier settings of prostate cancer) CRPC: Castration-resistant prostate cancer Peak sales potential ≥ €1bn Page 69
  • 72. Addressing Multiple Life-Cycle Opportunities for Xofigo (Radium-223 dichloride) • Bayer Investor Presentation • Meet Management • June 2014Page 70 Life-Cycle Opportunities Repeat dosing in CRPC Higher dose in CRPC Earlier disease stages of CRPC Combination study in CRPC Expansion into additional cancer types Addressed Through Phase II trial assessing the short and long-term safety of re- treatment Phase II trial with dose higher than the approved 50 kBq/kg Phase I and/or II studies in breast cancer, osteosarcoma and potentially in additional cancer types Phase III combination trial with abiraterone / phase II combination with abiraterone or enzalutamide CRPC: Castration resistant prostate cancer Status initiated initiated initiated planned
  • 73. Adempas – First-in-Class sGC Stimulator for Treatment of PAH and CTEPH • Bayer Investor Presentation • Meet Management • June 2014  Oral soluble guanylate cyclase (sGC) stimulator approved for treatment of PAH and CTEPH  First and only drug receiving marketing authorization for the treatment of CTEPH  Launched in the US for treatment of PAH and CTEPH (10/13)  Launched in J for treatment of CTEPH (04/14) – filed for PAH (04/14)  Launched in first EU countries for CTEPH and PAH (04/14)  Collaboration with Merck & Co. announced in May 2014 - 50/50 cost/profit split, joint development and commercialization strategy *for indications PAH and CTEPH; CTEPH; : Chronic thromboembolic pulmonary hypertension; PAH: Pulmonary arterial hypertension Peak sales potential ≥ €0.5bn* Page 71
  • 74. Adempas – Life Cycle Management Beyond PAH and CTEPH • Bayer Investor Presentation • Meet Management • June 2014 PAH: Pulmonary arterial hypertension; CTEPH: Chronic thromboembolic pulmonary hypertension; PH-ILD: Pulmonary hypertension due to interstitial lung disease Page 72  Positive phase II data in PH-ILD prompt initiation of phase IIb in PH-IIP (a specific sub- segment of PH-ILD)  Majority of PH-IIP patients suffer from pulmonary hypertension due to idiopathic pulmonary fibrosis  No approved treatment option  Chronic systemic autoimmune disease characterized by fibrosis  No approved treatment  Strong preclinical antifibrotic data Pulmonary hypertension with idiopathic interstitial pneumonia (PH-IIP) Diffuse systemic sclerosis (SSc)
  • 75. Page 73 Accelerating the Development of 5 early/mid-stage Pipeline Assets • Bayer Investor Presentation • Meet Management • June 2014 R&D
  • 76. Five New Molecular Entities Selected For Accelerated Development • Bayer Investor Presentation • Meet Management • June 2014Page 74 Project Mechanism Indication Status Copanlisib (BAY 80-6946) PI3-Kinase Inhibitor Cancer Phase II in NHL ongoing Finerenone (BAY 94-8862) MR Antagonist Chronic heart failure (CHF) Diabetic nephropathy (DN) Phase IIb in CHF and phase II in DN ongoing Molidustat (BAY 85-3934) HIF-PH Inhibitor Anemia Phase IIb ongoing Vericiguat (sGC-Stimulator BAY 1021189) sGC Stimulator Worsening chronic heart failure Phase IIb ongoing; collaboration with Merck & Co. Inc. Vilaprisan (sPRM) (BAY 1002670) Progesterone Receptor Antagonist Symptomatic uterine fibroids Phase IIb ongoing MR: Mineralocorticoid receptor; NHL: Non-Hodkin´s lymphoma HIF-PH: HIF prolyl hydroxylase; sGC: Soluble guanylate cyclase; sPRM: Selective progesterone receptor modulator
  • 77. Positive Proof-of-Concept Increases Confidence in NME-quality • Bayer Investor Presentation • Meet Management • June 2014Page 75 NME: New molecular entity CHF: Chronic heart failure EPO: Erythropoietin Copanlisib Finerenone Molidustat Vericiguat (sGC-Stimulator) Vilaprisan (sPRM) 100% of patients (6/6) with follicular lymphoma achieved a partial response as best response in phase I Phase II results in CHF patients suggest improved safety with at least similar efficacy compared to spironolactone Improvement in important cardiological parameters observed in phase I Significant increase in levels of endogeneous EPO and reticulocytes demonstrated in phase I Phase IIa data demonstrated reversible induction of amenorrhea
  • 78. • Bayer Investor Presentation • Meet Management • June 2014Page 76 Copanlisib (BAY 80-6946) – A PI3K-Inhibitor in Phase II in Cancer ● In most tumor cells, the PI3K-signaling cascade is activated and provides important tumor growth and survival signals ● Copanlisib is a pan class I PI3K-inhibitor with dominant  activity ● Copanlisib has shown a broad anti- tumor spectrum in preclinical tumor models ● Phase II in Non-Hodgkin’s lymphoma is ongoing; completion expected 1H 2015 Phosphatidylinositol-3 kinases (PI3K) play a central role in cellular signal transduction processes Copanlisib
  • 79. • Bayer Investor Presentation • Meet Management • June 2014Page 77 Copanlisib Has Shown Substantial Activity in Follicular Lymphoma *Data from Patnaik A et al.; ASH 2012; 18FDG-PET: 18fluorodeoxyglucose - positron emission tomography 18FDG-PET scans of a follicular lymphoma patient with partial response ● Phase I trial successfully completed ● 100% of patients (6/6) with follicular lymphoma (FL) responded to therapy achieving a partial response as best response* ● Maximum response duration > 840 days ● Encouraging signals in diffuse large B cell lymphoma patients ● 18FDG-PET data suggest that Copanlisib has rapid antitumor activity 52-year-old female with FL, grade 1-2, diagnosed stage IVa
  • 80. • Bayer Investor Presentation • Meet Management • June 2014Page 78 Selective Progesterone Receptor Modulation for Treatment of Uterine Fibroids ● Uterine fibroids are the most common benign tumors in women of reproductive age: 5-10% of premenopausal population suffers from symptomatic fibroids ● Symptoms may include heavy menstrual bleeding and tumor size related symptoms ● Current therapies include surgical procedures or short-term use of GnRH analogs for estrogen depletion ● Growth of fibroids strongly depends on progesterone and estrogen ● Progesterone receptor modulation may offer long-term treatment of uterine fibroids without estrogen depletion side effects of GnRH analogs GnRH: Gonadotropin-releasing hormone sPRM: Selective progesterone receptor modulator PR Transcription Activation Endometrial Modulation & Fibroid Growth sPRM Transcription Endometrial Modulation & Fibroid Growth PR
  • 81. • Bayer Investor Presentation • Meet Management • June 2014Page 79 Vilaprisan (sPRM; BAY 1002670) – For the Treatment of Symptomatic Uterine Fibroids ● Vilaprisan is a novel oral, highly potent and selective progesterone receptor modulator ● Exhibits marked efficacy in an innovative humanized fibroid disease model1 ● Phase IIa data (N=67) showed proof of concept including: ● Reduction of bleeding: induced amenorrhea (non-bleeding) in >60% of women treated with dosages >1mg/day ● Reversal of amenorrhea after treatment cessation ● No prohibitive safety findings 1 Wagenfeld et al. Hum Reprod. 2013 Aug;28(8):2253-64 Phase IIa data BAY Vilaprisan Dose effect curve for amenorrhea rate 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0102030405060708090100 Point estimate (median) 90% Credible interval Observed rate Efficacy threshold Dose (mg) Amenorrhearate(%)
  • 82. • Bayer Investor Presentation • Meet Management • June 2014Page 80 Renal Anemia is an Important Area of Unmet Medical Need ● Diseased kidneys do not produce sufficient levels of erythropoietin (EPO) in response to hypoxia, leading to anemia ● CKD/ESRD is the leading cause of anemia in industrialized countries ● Substitution with parenteral EPO is standard of care – however, un- physiologically high EPO doses correlate with significant side effects ● There is a need for novel therapies that lack the side effects of high doses of EPO-substitution CKD: Chronic kidney disease ESRD: End-stage renal disease Anemia Low oxygen level (Hypoxia) Normal kidney function Impaired kidney function EPO Red blood cell formation EPO Normal red blood cell count Insufficient formation of red blood cells
  • 83. • Bayer Investor Presentation • Meet Management • June 2014Page 81 Molidustat – An Oral HIF-PH Inhibitor for Treatment of Renal Anemia Increased red blood cell production Inhibition of HIF-PH increases the stability of HIF resulting in production of endogeneous EPO - potential novel therapeutic approach for the treatment of renal anemia Under normal oxygen conditions, HIF gets hydroxylated by HIF-PH and then degraded Under hypoxia conditions, HIF is activated and induces the synthesis of erythropoietin (EPO) in the kidneys which stimulates red blood cell formation Nucleus HIFHIF Low oxygen levels HIF Hydroxylation HIF Normal oxygen levels HIF-PH O2 hHIFhHIF Degradation Degraded HIF HIFHIF Inhibition of HIF-PH in renal anemia HIF-PH O2 EPO ↑ Nucleus EPO ↑ Nucleus Increased red blood cell production HIF: Hypoxia-inducible factor HIF-PH: HIF prolyl hydroxylase (enzyme) hHIF: hydroxylated HIF
  • 84. • Bayer Investor Presentation • Meet Management • June 2014Page 82 Molidustat (BAY 85-3934) – Proof of Concept Demonstrated EPO: Erythropoietin HIF-PH: HIF prolyl hydroxylase ● Molidustat is a novel oral inhibitor of the enzyme HIF-PH ● In development for the treatment of anemia associated with chronic kidney disease ● Phase I in healthy subjects showed: ● Significant increase of EPO levels after ≥ 12.5 mg ● Significant increase of reticulocytes for doses ≥ 37.5 mg ● No prohibitive safety findings Maximal EPO concentration after single dose administration of Molidustat (Phase I) 0 10 20 30 40 50 Placebo 5 mg 12,5 mg 25 mg 37,5 mg 50 mg EPO[U/L] Dose
  • 85. • Bayer Investor Presentation • Meet Management • June 2014Page 83 MR-Inhibition is a Proven Principle in the Treatment of Heart Diseases MR: Mineralocorticoid receptor HF: Heart failure aldosterone / cortisol Overactivated MR causing e.g.   Na+ and water retention  K+ loss  Hypertensive effects  Vascular  inflammation/injury  Myocardial/renal fibrosis  Proteinuria MR antagonist KidneyHeart  MR has multiple functions:  Regulation of salt, fluid homoestasis and blood pressure  Mediator of oxidative stress, subsequent inflammation, fibrosis and cardiorenal disease  Steroidal MR antagonists spironolactone and eplerenone have been shown to be effective in reducing cardiovascular mortality in patients with HF but are underutilized due to the risk of hyperkalaemia, renal dysfunction and anti-androgenic / progestogenic side effects  Steroidal MR antagonists are not approved for kidney diseases eg. diabetic nephropathy
  • 86. • Bayer Investor Presentation • Meet Management • June 2014Page 84 Finerenone – A Novel Non-Steroidal and Selective MR-Antagonist CHF: Chronic heart failure; CKD: Chronic kidney disease BNP: Brain natriuretic peptide; B. Pitt et al., Eur. Heart J. 2013; doi:10.1093/eurheartj/eht187 Mean increases in serum potassium concentration Finerenone10mg o.d.: 0.21 mmol/l Spironolactone: 0.45 mmol/l P <0.001 Mean change in estimated glomerular filtration rate Finerenone10mg o.d.: -2.69 ml/min/1.73m² Spironolactone: -6.70 ml/min/1.73m² P <0.05 Median change from baseline in NT-proBNP Finerenone 10mg o.d.: -193 pg/mL Spironolactone: -170 pg/mL (descriptive analysis) Decreased BNP/NT-proBNP – a key parameter for cardiac stress Indicates lower incidence of hyperkalaemia Indicates lower incidence of worsening of renal function Phase II results suggest improved safety with at least similar efficacy on key cardiac and renal parameters compared to spironolactone Data at Day 29 +/- 2 in part B of the study with 392 pts in total;Spironolactone was given at an initial dose of 25mg o.d. and uptitrated to 50mg o.d. on day 15±1 if sodium potassium concentration remained ≤4.8mmol/L; * eGFR 30-60 ml/min/1.73m² Key phase II findings in patients with CHF and moderate* (part B) CKD :
  • 87. • Bayer Investor Presentation • Meet Management • June 2014Page 85 sGC Modulation Has Significant Potential  Cardiovascular diseases to be the #2 therapeutic area by 2019**  Significant areas of unmet medical need including heart failure, forms of pulmonary hypertension, resistant hypertension, etc.  Recently discovered mechanism of sGC modulation holds promise to address several areas of unmet need Unmet Medical Need in Cardiovascular Diseases sGC Modulation * sGC: Soluble guanylate cyclase; *cyclic guanosine monophosphate **DecisionResources 2014
  • 88. Strategic Pharma sGC Collaboration with Merck & Co. Inc.  Maximize potential of all pipeline assets  Leverage R&D expertise in cardiovascular  Improve funding capabilities – thereby maximizing commercial potential of pipeline assets  Optimize combined marketing & sales power Collaboration between Merck and Bayer on sGC modulation to Page 86 Joint development and commercialization strategy with global 50-50 cost and profit sharing Merck to pay Bayer up to $2.1bn, comprising $1.0bn up-front and up to $1.1bn in contingent milestone payments • Bayer Investor Presentation • Meet Management • June 2014
  • 89. Maximizing the Potential of sGC Modulation  Bayer has marketing rights in Americas; Merck in all other territories  Co-promotion option for both parties in territories of other party  Enables Bayer to build its commercial presence in US specialty pharma while maximizing value of Adempas *scope defined by sGC mechanism Adempas (Riociguat) Vericiguat (BAY 1021189)  Merck has marketing rights in Americas; Bayer in all other territories  Co-promotion option for both parties in territories of other party  Maximizes value of Vericiguat by leveraging Merck’s US strength Early/Future Pipeline Assets*  Option to include other sGC pipeline assets (of both parties) that successfully complete Phase 1 in the next 5 years  Global 50/50 cost/profit split; joint development and commercialization strategy Page 87 • Bayer Investor Presentation • Meet Management • June 2014
  • 90. • Bayer Investor Presentation • Meet Management • June 2014Page 88 sGC Stimulation to Address Unmet Medical Need in Patients with Heart Failure ● Worsening chronic heart failure is an established indication with high medical need ● Limitations of standard of care include tolerance, oxidative stress, endothelial dysfunction and venoselectivity ● sGC stimulation can improve hemodynamics via restoration of cardiac and vascular cGMP signaling ● sGC stimulation may provide a new principle to reduce event rates in patients with worsening chronic heart failure Clinicalstatus Patients who require hospitalization due to HF (worsening HF) have a poor prognosis with high rates of re-hospitalization and death sGC: Soluble guanylate cyclase HF: Heart failure
  • 91. • Bayer Investor Presentation • Meet Management • June 2014Page 89 Vericiguat (sGC Stimulator; BAY 1021189) – Improvement of Cardiovascular Function sGC: Soluble guanylate cyclase HF: Heart failure Phase I of Vericiguat show improved cardiac output (n = 36) Fi gur e: Means and st andard devi at i ons f or i mpedance cardi ography over t i me f or Cardi ac Out put (L/ mi n) over t i me (val i d f or PD) Day 1 0H 00M 1H 00M 2H 00M 3H 00M 4H 00M 3. 0 3. 5 4. 0 4. 5 5. 0 5. 5 6. 0 6. 5 7. 0  Placebo  5 mg  7.5 mg  10 mg 0 1 2 3 4 Time (h) 33.544.55.05.56.06.57.0  Vericiguat is a novel sGC stimulator suitable for once-a-day dosing  Phase I successfully completed – improvement observed in important cardiological parameters, including:  Cardiac output / index (“volume of blood pumped by the heart”)  Systemic vascular resistance  Stroke volume  No untoward safety findings in phase I  Collaboration with Merck & Co (50/50 cost/profit split), joint development and commercialization strategy Cardiacoutput(L/min)
  • 92. The New sGC Franchise is Strong in the Industry Phase I Phase III Submitted LaunchedPhase IIIndicationProject PAH/CTEPH PH-IIP dSSc CF wCHF PH PH-HF Adempas Vericiguat MK 8892* rHT Research* in preparation in preparation in preparation Research/ Preclin. • Bayer Investor Presentation • Meet Management • June 2014Page 90 PH: Pulmonary hypertension; PAH:Pulmonary arterial hypertension; CTEPH: Chronic thrombmoembolic PH; PH-IIP: PH assoc. with interstitial idiopathic pneumonia; dSSc: Diffuse systemic sclerosis; CF: Cystic fibrosis; wCHF: Worsening chronic heart failure; rHT: Resistant hypertension; HF: Heart failure *Potential collaboration assets, subject to execution of options in the next 5 years after successful completion of Phase 1 BAY sGCstim * BAY sGCact * Raynaud’s
  • 93. Major Expected Pharma Pipeline Newsflow 2014/2015 • Bayer Investor Presentation • Meet Management • June 2014 Estimated primary study completion as of May 2014 HCC: Hepatocellular carcinoma; NHL: Non-Hodkin‘s lymphoma;; MR: Mineralocorticoid receptor; HF: Heart failure; PI3-Kinase: Phosphatidylinositol-3 kinases, sGC :Soluble guanylate cyclase; HIF-PH: HIF prolyl hydroxylase Page 91 2014 2015 BAY 85-8501 (Elastase Inhibitor) Completion of phase II in bronchiectasis Copanlisib (PI3-Kinase Inhibitor) Completion of phase II in NHL Stivarga Completion of phase III in 2nd-line HCC Finerenone (MRAntagonist) Completion of phase II in diabetic nephropathy Vericiguat Completion of phase II in worsening chronic HF Molidustat (HIF-PH Inhibitor) Completion of phase II Finerenone (MR Antagonist) Completion of phase II in worsening chronic HF Nexavar Completion of phase III in breast cancer (RESILIENCE) Vilaprisan (SPRM) Completion of phase II
  • 94. • Bayer Investor Presentation • Meet Management • June 2014 Established Pharma Products Page 92
  • 95. 2010 2011 2012 2013 Hemophilia Franchise – Stable Growth • Bayer Investor Presentation • Meet Management • June 2014  Global # 2 in hemophilia A treatment  Competitive portfolio in hemophilia:  Positive phase III data with site- directed PEGylated long-acting Factor VIII (BAY 94-9027)  Product from plasma-free process (BAY 81-8973) – filing planned for 2014  Investment of € >500m planned to establish additional manufacturing capacities for recombinant FVIII products in development Sales in € million; ∆% Fx adj. 299 705 290 785 332 850 US Rest of the world 1,004 1,075 1,182 +6% Page 93 330 872 1,202
  • 96. Prophylaxis in Hemophilia – Breakthrough in Prolonging Dosing Intervals • Bayer Investor Presentation • Meet Management • June 2014Page 94  Prophylaxis can protect hemophilia patients more effective compared to on- demand treatment in terms of  Reducing frequency and severity of bleeding episodes  Preserving joint health/function and  Maintaining overall long-term health status  However, current standard in prophylaxis involves two to three infusions per week  A long-time goal in hemophilia prophylaxis has been to reduce the burden from frequent infusions  PROTECT VIII demonstrated evidence of reliable prophylaxis of bleeding in hemophilia A with dosing at every 5 and 7 day intervals
  • 97. Expanding the Hemophilia Franchise – Long- Acting Site-directed PEGylated Factor VIII • Bayer Investor Presentation • Meet Management • June 2014Page 95  Damoctocog alfa pegol (BAY 94- 9027) is a B-domain–deleted recombinant factor VIII (BDD-rFVIII) with site-specific PEGylation  Attachment of PEG extends half-life without reducing FVIII activity  Positive PROTECT VIII phase III data  Filing US, EU and other regions planned for 2H’2015 Site-specific PEGylation to extend FVIII half life B-domain deletion
  • 98. Damoctocog alfa pegol (BAY 94-9027) – Design of the PROTECT VIII Phase III Study • Bayer Investor Presentation • Meet Management • June 2014Page 96  PROTECT VIII is a pivotal study assessing safety and efficacy of the site- directed PEGylated FVIII Damoctocog alfa pegol  Part A: On-demand and prophylactic treatment (completed)  Part B: Major surgery (ongoing) 6 Randomization 0 10 14 20 28weeks 2x/week 25 IU/kg (n  120) 2 or more breakthrough bleeds: No or 1 breakthrough bleeds: 36                    Screening Screening 2   On‐demand therapy individual dosage n=20 2x/week 30 to 40 IU/kg n=24* Every 5 days 45‐60 IU/kg n=43 Every 7 days 60 IU/kg n=43 * 13 assigned due to bleeding; 11 default/randomization arms full 38
  • 99. Damoctocog alfa pegol Phase III Results - Reduction of Infusion Frequency in Prophylaxis • Bayer Investor Presentation • Meet Management • June 2014Page 97  Met primary objective of protection from bleeds with fewer infusions  Extending infusion intervals up to 7 days resulted in protection from bleeds  No inhibitors against FVIII developed during treatment period Study Arm Patients (n) remaining on treatment Patients with no bleeding Median ABR Prophylaxis: infusion 2x/week n.a. n.a. 17.4 (reduction to 4.1 after dose increase) Prophylaxis: infusion every 5 days 43/43 44% 1.9 Prophylaxis: infusion every 7 days 32/43 37% (incl. non-completers) 3.9 * (incl. non-completers) On-demand treatment n.a. n.a. 23.0 ABR: Annualized bleeding rate *Median ABR for the 32 (74%) completers was 0.96
  • 100. The Leader in Women’s HealthCare • Bayer Investor Presentation • Meet Management • June 2014 Yaz family Sales ∆% y-o-y, () FX adj. Women’s Healthcare 2013 €3,034m -7% (-1%)* +6 (+10)Mirena -23 (-16)Diane -18 (-13) +7 (+12)Qlaira Other products +1 (+7) -13 (-8)Microgynon -2 (0)Valette -13 (-8)Meliane -7 (-1)Angeliq Page 98 * Fx & portf. adjusted growth -4% due to Essure with €74m sales in 2013
  • 101. • Bayer Investor Presentation • Meet Management • June 2014 Strengthening Women‘s Health Business – Acquisition of Conceptus, Inc.  Bayer successfully completed the public tender offer to acquire all shares in Conceptus for a purchase price of €780m  US-based company developing the Essure® procedure, the leading non- surgical permanent birth control method proven by >700,000 procedures  Significant synergies expected from leveraging existing business power Essure ® Permanent Long-term Short-term No children Active family planning Family planning finalized IUD (Mirena) IUD (Skyla) Oral contraceptives (e.g. YAZ) Page 99
  • 102. Mirena – The Leading Hormonal Long- Acting Contraceptive • Bayer Investor Presentation • Meet Management • June 2014  Intrauterine device, containing levonorgestrel, for reversible long- term contraception  Life-cycle opportunities:  Small low-dose long-acting (up to 3 years) device:  Jaydess; launched in EU  Skyla; launched in the US  Phase III for a long-acting (up to 5 years), low-dose, small contraception device underway Sales in € million; ∆% Fx adj. 2010 2011 2012 2013 285 254 313 268 385 292 US Rest of the world 539 581 677 +10% Page 100 415 304 719
  • 103. Betaseron – Long-term Experience in Multiple Sclerosis Treatment • Bayer Investor Presentation • Meet Management • June 2014  First interferon launched in multiple sclerosis, introduced in 1993  Wealth of clinical experience  Demonstrating excellent efficacy and tolerability  21-year long-term follow-up study demonstrated significant survival advantage with Betaseron treatment  Launch of BETACONNECT (new electronic auto-injector) in Europe underway Sales in € million; ∆% Fx adj. 2010 2011 2012 2013 473 733 447 670 578 638 US Rest of the world 1,206 1,117 1,216 -12% Page 101 499 539 1,038
  • 104. Nexavar – Our Cornerstone in Oncology • Bayer Investor Presentation • Meet Management • June 2014  Approved for kidney cancer (RCC), liver cancer (HCC) and radioactive iodine refractory differentiated thyroid cancer (DTC)  Only approved drug with overall survival benefit in HCC  Phase III trials in:  Breast cancer  RCC (adjuvant) Sales in € million; ∆% Fx adj. 2010 2011 2012 2103 174 531 174 551 204 588 US Rest of the world 705 725 792 +3% Page 102 219 552 771
  • 105. Aspirin – Sustainable for More Than A Century • Bayer Investor Presentation • Meet Management • June 2014  One of the world’s most recognized brands  Available as OTC and Rx Aspirin  Bayer’s #1 product in Emerging Markets; 8% growth in China in 2013 Sales in € million; ∆% Fx adj. 2010 2011 2012 2013 358 418 404 471 476 494 Rx-Aspirin OTC-Aspirin 776 875 970 -1% Page 103 452 464 916
  • 106. • Bayer Investor Presentation • Meet Management • June 2014Page 104 Aspire to Become the Leading OTC Company
  • 107. Evolution of Bayer Consumer Care’s OTC Business 2008 Acquisition of OTC brand portfolio from Sagmel (CEE) and Topsun (China) 1999 Aspirin trademark centenary-worldwide sales > €500m 1899 ASPIRIN introduced as an over-the-counter (OTC) medicine 1994 Consumer Care business group created by the acquisition of North American OTC business of Sterling; Acquisition of the “Bayer Cross” Trademark in USA 2005 Acquisition of Roche Consumer Health 2013 Aspirin trademark sales of >€900m Acquisition of Steigerwald (Germany) Page 105 • Bayer Investor Presentation • Meet Management • June 2014 2014 Proposed acquisition of Merck’s Consumer Care business (US) Transaction agreement signed with Dihon Pharmaceutical Group (China)
  • 108. • Bayer Investor Presentation • Meet Management • June 2014Page 106 Growth Strategy  Maximize brand potential  Global expansion of key brands  Exploit our innovation pipeline  Grow in emerging markets  Increase commercial power  Bolt-on acquisitions to strengthen portfolio & regional set-up 3.4 3.5 3.9 3.9 2010 2011 2012 2013 +5% +7% +6% Consumer Care sales in € billion; ∆% Fx & portfolio adj. Bayer Consumer Care – Outperforming Markets in Past 7 Out of 8 Years
  • 109. Merck’s Consumer Care Business Fits Perfectly With Bayer Consumer Care • Bayer Investor Presentation • Meet Management • June 2014 Complementary Portfolio Building on core competencies  Creation of a global leader in OTC  Gaining scale in key categories CASF1, dermatology, and gastrointestinal  Optimizing footprint in North America  Strong track record of growing OTC brands  Strong geographical presence to broaden Merck’s portfolio globally  Utilizing integration skills from past transactions Page 107 Acquisition criteria fulfilled  Creating leadership positions in important consumer care categories and geographies  Increasing consumer care margin2 by ~1pp from year 1  Immediate core EPS accretion from year 13 1 cold, allergy, sinus, flu; 2 EBITDA pre-special items; 3 transaction incl. sGC collaboration
  • 110. Page 108 • Bayer Investor Presentation • Meet Management • June 2014 Combined Portfolio Significantly Strengthens Global Positions Gastrointestinal Analgesics3 CASF2 Nutritionals Dermatology1 Total Others4 3,904 1,635 5,539 1,110 386 372 803 126 513 439 141 1,023 834 1 including sun care; 2 Cold, Allergy, Sinus, Flu; 3 including Cardio; 4 Foot Health, Women’s Health, Other 1,496 1,023 1,175 834 580 431 #1 #2 #3 #1 #2 Global position*2013 Sales in €m (pro-forma portfolio) Note: Merck sales converted at average USD rate of 1.33 (FY 2013) 305 *After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx MerckBayer
  • 111. Page 109 • Bayer Investor Presentation • Meet Management • June 2014 Combined Portfolio Significantly Strengthens Geographic Footprint Note: Merck sales converted at average USD rate of 1.33 (FY 2013) *After allowing for the Novartis/Glaxo deal; excluding Dihon acquisition in China; excluding Rx Latin America Europe North America Total Asia/Pacific 3,904 1,635 5,539 1,117 1,105 1,621 170 389 513 141 777 2,222 1,791 946 580 #1 #1 #5 #2 Global position*2013 Sales in €m (pro-forma portfolio) 191 169 MerckBayer
  • 112. FY 2013 sales in € million (∆% yoy Fx-adj.) 321 310 232 214** 207 176 158 257 *Total Aspirin includes Aspirin Complex and Aspirin Cardio (Rx) **Total Alka-Seltzer includes Alka-Seltzer and Alka-Seltzer Plus 916* = Rx Sales Page 110 • Bayer Investor Presentation • Meet Management • June 2014 Combined Top 10 Portfolio – Individual Brands with Annual Sales >€100m 576 Note: Merck sales converted at average USD rate of 1.33 (FY 2013); based on pro-forma FY 2013 net sales
  • 113. • Bayer Investor Presentation • Meet Management • June 2014Page 111 Top Priorities To Be Executed Immediately After Closing of Transaction…  Ensure fast integration into operations  Safeguard product supply  Realize synergy potential  Prioritize brand strategies within combined portfolio  Realize Merck brand penetration opportunities ex-US  Define and execute individual brand strategies  Develop US scale advantage  Strive for leadership with trade customers  Provide a broader product portfolio Critical mass in US Brand Roll- Out ex-US Smooth integration
  • 114. • Bayer Investor Presentation • Meet Management • June 2014Page 112 Clear Strategy For a Smooth Integration 2014 Q2 2014 Q42014 Q3 2015 (End State)  Smooth integration expected due to experienced management team • Ensure effective integration into Consumer Care • Safeguard on-going product supply • Prioritize and execute identified brand development / expansion strategies • Ensure sufficient future capacity for growth • Capitalize on Merck’s innovation capabilities • Achieve scale and revenue synergies • Capture consolidation and efficiency synergies by 2017  Deal signing  Deal closing  Consolidation / Integration
  • 115. • Bayer Investor Presentation • Meet Management • June 2014Page 113 Enhanced Scale and Broader Category Scope Improve Product Offerings US Retail Sales CASF Benefits from Enhanced Scale  Co-promoting complementary brands  New item assortment and shelving opportunities  Improved merchandising efficiencies  Bigger and more impactful trade events  Foster strategic partnerships with retailers FY 2013 retail sales in CASF in $ million* $- $200 $400 $600 $800 $1,000 $1,200 RB Bayer & Merck J&J Merck & Co. P&G Pfizer Chattem Bayer GSK *Source: IRI; Latest 52WK; December 2013  Make Bayer Consumer Care Top Strategic Partner for US Retailers
  • 116. Maximizing Brand Potential Through Global Expansion Brand Sales by Major Region 2013 Expansion Plans • Bayer Investor Presentation • Meet Management • June 2014Page 114 Analgesic ~80% in North America ~95% in North America Wound-healing ~75% in Europe Anti-fungal ~75% in Europe & LatAm Vitamins & minerals ~50% in Europe ~80% in North America CASF Sun Care
  • 117. • Bayer Investor Presentation • Meet Management • June 2014Page 115 Russia Country OTC Market Sales Growth 2013* Execution Plans China  Global #2  Growing 2x the global rate  Use investments in footprint, brand-building and sales capabilities to extend Claritin leadership  Build sun care category with Coppertone Brazil  Global #7  Fastest growing market in LATAM  Use investments in brand-building and channel capabilities to develop key new categories (sun care, foot care, allergy)  Revitalize Coppertone and Dr. Scholl’s brands Russia  Global #4  Retail OTC is largest healthcare segment  Focus on CASF brands using current position to roll-out extended offerings  Achieve #2 position Execution Plan Focused on Key Brands in Key Emerging Markets +38% +26% +14% *Bayer Consumer Care sales, currency-adjusted
  • 118. Consumer Care is Well-Positioned for Growth – Aspire to Clear OTC Leadership OTC Market Attractive Bayer Has Strong #2 Position Plans for Continued Future Growth  Trends favor continued growth  OTC market model based on long-term brand building  OTC businesses becoming more valuable over time  Leader in key categories  Multiple strong brands  Track record of outperforming market growth  Globalize established brands & launch innovation pipeline  Focus on emerging markets where most of growth will come  Strategic acquisitions and alliances Page 116 • Bayer Investor Presentation • Meet Management • June 2014
  • 119. • Bayer Investor Presentation • Meet Management • June 2014Page 117 Animal Health – Operating in an Attractive Market Environment
  • 120. • Bayer Investor Presentation • Meet Management • June 2014Page 118 Demonstrating a Solid, Long-Term Sales Growth Trajectory Sales in € million; ∆% Fx & portfolio adj.  Overall global #5 and global #2 in parasiticides  Ranked #3 in CAP (~60% of sales)  Sector driven by:  Emotional relationships to pets  Infectious and chronic diseases  Ranked #7 in FAP (~40% of sales)  Sector driven by:  Increasing customer/consumer awareness  Food safety & disease transmission  Globalization in farm exports Highlights 977 1,120 1,186 1,303 1,306 2009 2010 2011 2012 2013 +4%
  • 121. • Bayer Investor Presentation • Meet Management • June 2014Page 119 Aspiring Further Sustainable Growth 6% AH Market 2013 by Player Zoetis Merck Merial Elanco Bayer Boehringer I. Novartis Virbac CEVA Others €21bn Growth Strategy  Expand market share of existing portfolio while delivering innovation  Strengthen and expand 2013 acquired TEVA US AH business  Drive research & development at a 10% sales ratio  Explore M&A opportunities for further growth
  • 122. • Bayer Investor Presentation • Meet Management • June 2014Page 120 New Innovative Product Examples – Recent Launch Highlights  New benchmark for flea and tick protection  Outstanding efficacy based on combination of active ingredients  Up to 8 months protection due to innovative polymer matrix technology  Pradofloxacin, the new generation fluoroquinolone  Extended spectrum vs. previous fluoroquinolones  Greater potential to limit selection for resistance  Convenient formulations for dogs and cats  1st combined endopara- siticide against roundworm and coccidia in dogs  Easy and convenient once daily oral treatment  Can be used at 2-weeks old
  • 123. • Bayer Investor Presentation • Meet Management • June 2014Page 121 Innovative Life-Cycle Management – Example of Advantage Family Highlights 2002 2013 202 487 Sales in € million  Successful franchise through:  Brand building – investments in direct-to-consumer for brand awareness  Channel diversification – meeting consumers where they are  Life Cycle Management (LCM) – ongoing with new claims
  • 124. • Bayer Investor Presentation • Meet Management • June 2014Page 122 Selected R&D Activities New formulations Antimicrobials Pharmaceutical SpecialtiesParasiticides Focus to improve:  Convenience  Efficacy  Safety  Antibiotics (Quinolones)  Dairy Health  Respiratory Diseases Products  Allergy & Inflammation  Chronic Kidney Disease  Ecto- parasiticides  Endo- parasiticides  Endecto- parasiticides R&D Investment approx. 10% of turnover
  • 125. • Bayer Investor Presentation • Meet Management • June 2014Page 123 Medical Care – Diabetes Care and Radiology DC & R
  • 126. • Bayer Investor Presentation • Meet Management • June 2014Page 124 Radiology & Interventional Diabetes Care Sales Split 2013 Medical Care €2,526m; -5% (0%) 40% 60% Medical Care – Strong Legacies in Diabetes Care and Radiology In € million, ∆% yoy, () = Fx & portf. adjusted Diabetes Care:  Comprises self testing blood glucose monitoring devices Radiology  Combines our Contrast Media, Injector and Informatics businesses
  • 127. • Bayer Investor Presentation • Meet Management • June 2014Page 125 Diabetes Care – Global Player in Blood Glucose Meters Highlights Sales in € million; ∆% Fx & portfolio adj. 1,000 993 1,002 1,047 1,007 2009 2010 2011 2012 2013 -1%  Global #3 in blood glucose meters  Stable business performance despite difficult market conditions  Market characterized by growth in prevalence, but pricing pressure  Latest innovation products include CONTOUR® Next and Next Link  MULTIPULSE technology ensures high accuracy blood glucose measurements  Wireless transmission of results to Medtronic insulin devices
  • 128. • Bayer Investor Presentation • Meet Management • June 2014Page 126 1,363 1,474 1,498 1,606 1,519 2009 2010 2011 2012 2013 Sales in € million; ∆% Fx & portfolio adj. 0% Radiology – Leading Positions in Contrast Media and Application Devices  Integrated subsidiary Medrad Inc. and our contrast media business  The business comprises:  Contrast media: CT and MRI  Contrast media injectors: Medrad brand  Informatics  Services  Synergies through focus on similar centers / physicians Highlights
  • 129. Investor Handout – Meet Management Bayer CropScience June 2014 – New York
  • 130. 18% 25% 11% 11% 7% 28% Sales 2013: €8,819m Insecticides€1,622m Market position: Fungicides€2,195m 3Market position: SeedGrowth€921m 1-2Market position: Herbicides €2,456m 4Market position: Env. Science €651m 1Market position: Seeds €974m 7Market position: Page 128 CropScience – A Leader in Chemical Crop Protection • Bayer Investor Presentation • Meet Management • June 2014 1 Market positions based on company reportings and Cropnosis estimates Page 128
  • 131. 25% 22% 14% 12% 8% 6% 6% 4%3% Fruits & Vegetables CerealsOilseeds Soy Corn Cotton Rice Sugar Crops * by major crop groups excluding industrial business and non-agricultural solutions CropScience Sales 2013* Other Fruits, Vegetables and Cereals – A Major Part of Our Portfolio • Bayer Investor Presentation • Meet Management • June 2014Page 129
  • 132. Leading the Way in Integrated Crop Solutions Integrated Crop Solutions Chemical Crop Protection Biological Crop Protection Seeds  Herbicides  Fungicides  Insecticides  SeedGrowth  Microorganisms  Microbial extracts  Canola, cotton, rice, vegetables, soy, wheat  Conventional seeds  GMO seeds  Traits  Weed, pest & disease control  Stress tolerance Better harvest with improved:  Yield  Quality  Processability  Sustainability GMO: Genetically modified organism • Bayer Investor Presentation • Meet Management • June 2014Page 130
  • 133. • Bayer Investor Presentation • Meet Management • June 2014Page 131 Strong Growth at Record Margin
  • 134. FY 2013 – Strong Growth at Record Margin Page 132 Crop Protection +7% (+11%) Environmental Science -4% (+1%) *before special items Seeds +1% (+1%) 2013 Sales Earnings In € million, ∆% yoy, () = Fx & portf. adjusted CropScience €8,819m; +5% (+9%) Price +3% Volume +7% Fx -5% Portfolio 0% 7,194 FY‘12 FY‘13 FY‘12 FY‘13 2,025 2,248 +11% 1,543 1,801 +17% Adj. EBITDA* Adj. EBIT* 651 974 24.2% 25.5%Margin • Bayer Investor Presentation • Meet Management • June 2014
  • 135. Emerging Economies 25% CropScience Sales in FY 2013 CropScience €8,819m; +5% (+10%) Latin America Eastern Europe Africa & Middle East Emerging Asia³ ~900 +11% ~2,200 +27% ~600 +9% ~300 +4% Page 133 17% USA +3% 25% 45% 13% Emerging Economies¹ +18% Western Europe +3% Others² +6% FY 2013 – Strong Growth in Emerging Economies Sales in € million, ∆% yoy Fx adjusted • Bayer Investor Presentation • Meet Management • June 2014 1: Emerging economies include: Latin America, Asia w/o Japan, Australia, New Zealand, Africa and Middle East incl. Turkey, Eastern Europe 2: Others = Japan, Australia, New Zealand, Canada; 3: Emerging Asia = Asia w/o Japan, Australia, New Zealand
  • 136. • Bayer Investor Presentation • Meet Management • June 2014 Successful Start to The Year Page 134
  • 137. Sales Earnings Q1 2014 – CropScience: Early Start to the Season in Europe Page 135 Crop Protection +6% (+12%) Environmental Science +1% (+8%) Seeds +3% (+12%) In € million, ∆% yoy, () = Fx & portf. adjusted CropScience €2,900m; +5% (+12%) Price +2% Volume +10% Fx -7% Portfolio 0% 2,231 Q1‘13 Q1‘14 Q1‘13 Q1‘14 1,081 1,098 +2% 969 988 +2% Adj. EBITDA* Adj. EBIT* 166 503 • Bayer Investor Presentation • Meet Management • June 2014 *before special items
  • 138. Herbicides Fungicides Seeds 503 +12% Insecticides Sales in € million; ∆% y-o-y Fx & portfolio adj. Q1 2013 Nominal growth Q1 2014 • Bayer Investor Presentation • Meet Management • June 2014 Env. Science Q1 2014 – Growth Driven by All Segments Page 136 965 +8% 662 +17% 352 +13% 252 + 19% 166 + 8% Seed Growth  Strong demand for cereal herbicides in Europe  Early start to the season in Europe; Growth in LatAm mainly driven by Fox  High demand in the US, especially for Poncho family in corn and soybean  Marked sales increase in Europe and LatAm; excellent performance of Belt  Growth in the Americas, mainly driven by cotton and vegetable seeds  Positive performance for both professional and consumer business
  • 139. • Bayer Investor Presentation • Meet Management • June 2014 Customer-Centric Strategy Pays Off Page 137
  • 140. Customer-Centric Strategy Pays Off Strengthen Customer Centricity Lead the Way in Innovation Enhance Crop Protection & Environmental Science  Striving for first- and best-in-class solutions  Exploiting expertise in seeds, breeding, and chemical and biological crop protection  Driving commercial excellence in marketing and sales  Connecting partners in the value chain through integrated Go-to-Market practices  Improving portfolio through focused and integrated crop solutions  Increasing flexibility and efficiency Expand Seeds Business  Further strengthening position in vegetables, rice, oilseed rape and cotton  Extending portfolio by building up business in soybean and wheat • Bayer Investor Presentation • Meet Management • June 2014Page 138
  • 141. Q1 2014 - Significant Contribution from New Crop Protection Products 1.1 1.5 1.8 2.6 2012 2013 2014e 2016e +33% Sales from new Crop Protection products launched since 2006 in €bn ∆% y-o-y, () Fx adj. • Bayer Investor Presentation • Meet Management • June 2014  (+16%) - Superior ‘all-in-one’ cereal fungicide with yield-boosting effect  herbicide (+14%) - Excellent weed control in corn and cereals, also in case of glyphosate resistance  (+75%) - Broad-spectrum insecticide with fast, long-lasting action  (+112%) - New fungicide now available in several key markets Q1 2014 Highlights Q1 0.6 Page 139
  • 142. Xpro – New Cereal Fungicide with Yield-Boosting Effect  Pyrazole fungicide from a new generation of SDHI* for foliar use in cereals  Combined formulation of Bixafen and Prothioconazole leading to superior "all-in-one" cereal fungicide Xpro  Excellent control of key cereal diseases including strobilurin-resistant Septoria  Boosting yield through long-lasting disease control and positive impact on plant physiology  Global peak sales potential of more than €300m * SDHI: Succinate dehydrogenase inhibitor • Bayer Investor Presentation • Meet Management • June 2014Page 140
  • 143. Luna – Outstanding Fungicide for Managing Problematic Crop Diseases  New SDHI* fungicide for use in foliar application and seed treatment on more than 70 horticultural and industrial crops  Control for a broad range of problematic diseases including Alternaria blight, scab, powdery mildew and white mold  Benefits for the food chain through better storability and longer shelf-life of harvested produce  Available since 2012 planting season in several key markets  Global peak sales potential of more than €250m * SDHI: Succinate dehydrogenase inhibitor • Bayer Investor Presentation • Meet Management • June 2014Page 141
  • 144. Adengo Family – Highly Effective Weed Control in Corn  Thiencarbazone-methyl is a new sulfonyl-amino- carbonyl-triazolinone (SACT) herbicide  Additional crop selectivity in combination with HPPD inhibitor Isoxaflutole and safener Cyprosulfamide Grower benefits:  Controls annual grasses and broad leaved weeds in corn including those that are resistant to glyphosate  Offering flexibility in application timing  Strong enough to achieve one-pass weed control  Rapid burndown, long-lasting residual control • Bayer Investor Presentation • Meet Management • June 2014 Peak sales potential of more than €350m Page 142
  • 145. Belt Insecticide - Preserve Yield Potential  Flubendiamide is a phthalic acid diamide  Acts as ryanodine receptor modulator, larvae loses muscle control Grower benefits:  Controls lepidoptera pests in a wide range of crops, including soybeans, corn and cotton  Fast action, larvae stops feeding immediately  Rainfast with excellent residual activity  Provides minimal risk to beneficial insects  Excellent resistance management tool • Bayer Investor Presentation • Meet Management • June 2014 Control + BELT® Heliothis Peak sales potential of more than €300m Page 143
  • 146. Sustainable Alternatives to Fight Glyphosate Weed Resistance • Bayer Investor Presentation • Meet Management • June 2014  Weed resistance to glyphosate increasingly impacting crop production; almost 50% of U.S. growers are affected  Our LibertyLink is currently the only non-selective herbicide solution to glyphosate resistant weeds  Significant expansion of production capacity for Liberty planned  We are committed to develop new and more sustainable weed management solutions  Highly effective pre-emergent and selective herbicide portfolio launched 100 200 300 400 2010 2011 2012 2013 Liberty/Basta Sales in €m Page 144
  • 147. Future Market Potential of Biologicals Expected to Increase Significantly  Biologicals are products derived from naturally-occurring living organisms or materials from plants or microorganisms  Increasing demand from consumers for safe and sustainably produced food, especially in fruits & vegetables area  Global retailers have more stringent residue reduction targets  Currently lower regulatory hurdles and faster registration process for biologicals compared to chemicals  Grower benefits from short pre-harvest and re-entry intervals and thus high flexibility on application timing  When used in combination or rotation with chemicals, biologicals provide new tools in resistance management • Bayer Investor Presentation • Meet Management • June 2014 Market potential expected to triple from $1.2bn in 2010 to $4bn in 2020 Page 145
  • 148. Further Growth Opportunities in Biologicals with Bolt-On Acquisitions  Successful market entry with nematode seed treatment Poncho/Votivo in 2011 (Sales 2013: €150m)  AgraQuest acquired in Q3 2012 for €375m including milestone payments. Global provider of innovative biological pest management solutions based on natural microorganisms  Prophyta acquired in Q1 2013, a provider of well-established products, e.g. nematicide BioAct  Biagro acquisition* adds nitrogen inoculants and plant health promoters  We aim to become the world leader in integrated crop solutions • Bayer Investor Presentation • Meet Management • June 2014 * Clearance by Antitrust Authority in Argentina outstanding Page 146
  • 149. Acquisition of Biagro to Strengthen our Soybean Business in Latin America  Argentinean company Biagro acquired in Q1 2014*  Biagro portfolio includes seed-applied biofertility inoculants and plant growth-promoting microorganisms  Acquisition is a further milestone to become a leader in biological seed treatments  Provides soybean growers in Latin America with innovative offerings to substantially improve productivity  Nitrogen essential for plant growth and soybean seed production  Biagro inoculants are a very effective and cost-efficient method of supplying nitrogen to soybeans and other legume crops • Bayer Investor Presentation • Meet Management • June 2014 * Clearance by Antitrust Authority in Argentina outstanding Inoculants containing high-quality Rhizobium bacteria strains enable plant roots to fix nitrogen from the atmosphere, resulting in enhanced plant growth, more vigorous root structure and greener plant foliage Page 147
  • 150. Customer Centricity Along the Entire Value Chain • Bayer Investor Presentation • Meet Management • June 2014 Bayer CropScience Our offers Growers Distributors/ seedcompanies Retailers Advisors Providing Seed-to-Shelf Solutions Traders Foodprocessors Foodretailers Consumers  Around 240 food chain partnerships covering most of the main fruit & vegetable crops and rice  Premium seeds and effective crop protection products to maximize yield  Consistent and high harvest quality for efficient food processing  Meeting highest food safety standards  Better product quality for the consumer Page 148
  • 151. Serving Grower Needs Beyond Crop Protection and Seeds • Bayer Investor Presentation • Meet Management • June 2014 Services Examples Providing agronomic support  Crop advice  Expert trainings  On-farm trials  Field days Optimizing yield and quality by offering diagnostic and prediction tools  Weather forecast  Pest prediction  Disease diagnosis  Resistance risk calculator  Assessment of quality indicators Helping to optimize application process and seeding  Application collaborating with machinery providers  Seed treatment equipment checks Creating transparency by offering tracking / documentation support  Field documentation  RoI calculation  Certification support Improving farm management by financing and insurances  Ag input financing  Barter business  Crop price insurance Page 149
  • 152. • Bayer Investor Presentation • Meet Management • June 2014 Translating R&D Effectively into Sales From to € Page 150
  • 153. Pipeline Peak Sales Potential  €4bn from Products Launched 2011 - 2016* • Bayer Investor Presentation • Meet Management • June 2014 Crop Protection Life Cycle Management Seeds Cotton Canola Wheat Soybean Rice 2013 ~110 launches in vegetables & broad acre crops Roundup Ready Hybrid Canola Fungicide Serenade Optimum Bayer Oilseed Mustard Hybrids Seed Varieties 2014 Canola Yield Increase Numerous launches in vegetables & broad acre crops Verango / Velum Insecticide Insect Resistant Hybrid Rice TwinLink + GlyTol Cotton Seed Varieties 20162015 *estimated and subject to regulatory approval 2 joint project with MS Technologies Constant Life Cycle Management through new formulations and mixtures that also includes Biologicals Disease Resistant + Salinity Tolerant Hybrid Rice Insect + Disease Resistant Hybrid Rice Improved Canola Oil Profile Dual Herbicide Tol. + Novel Insect Resistant Cotton Insecticide Biologicals Seed Varieties Numerous launches in vegetables & broad acre crops GlyTol + HPPD Tolerant Soybeans2 Biologicals Fungicide Bayer Wheat Seed LibertyLink + Roudup Ready Hybrid Canola Council Herbicide Disease Resistant + Submergence Tol. Hybrid Rice Seed Varieties Numerous launches in vegetables & broad acre crops Sivanto Insecticide Page 151
  • 154. Sivanto – Innovative and User-friendly Insecticide Against Sucking Pests  Active ingredient: flupyradifurone (novel insecticide class butenolides)  Control of sucking pests such as aphids, hoppers and whiteflies  Intended for use in fruits, vegetables, and broad acre crops  Favorable safety profile  Launch planned 2015* • Bayer Investor Presentation • Meet Management • June 2014 * first registrations for foliar application; SeedGrowth use planned to follow subsequentlyPage 152
  • 155. Biological Crop Protection for Mite Control  Mites can significantly reduce yields and quality  Leading to rejection of produce along the value chain and lower sales  Microbial acaricide with new mode of action  Season-long effectiveness: curative, eradicant, protective  Registration expected in the U.S. in 2016* • Bayer Investor Presentation • Meet Management • June 2014 * subject to regulatory approval Two-spotted spider mite under scanning electron microscope (SEM) Page 153
  • 156. Build up a Global Wheat Seed Business  Largest broad-acre crop worldwide  Market value still small, but major potential seen with productivity improvement  Hybrids provide opportunity for both yield increase and improved yield stability • Bayer Investor Presentation • Meet Management • June 2014 The Market* Our Efforts Our Goals • 7 breeding centers • Numerous collaborations • Significant R&D investments The Market • 226m ha of wheat acres, majority is farm-saved seed • Current market of €0.2bn (royalties only) • Slow productivity increase • Yield increase • Nitrogen use efficiency • Water use efficiency • Heat tolerance Market Entry • Launch of first variety planned in 2015 • Suitable for western and central regions of the Ukraine • Open pollinated variety * Source: FAO, Context Networks 2012 (seed co level) Corn: 60.7 EUR/ha  Wheat: 0.9 EUR/ha The Market Page 154
  • 157. Acquisitions in Latin America Broaden our Portfolio in Soybean Seed  Building up proprietary seed business with high quality germ- plasm pool  Establishing best-in-class breeding platform  Leveraging the potential of our trait platform through out-licensing  Launch of Bayer soybean brand Credenz planned late 2014  Integrated business model combining seeds & crop protection • Bayer Investor Presentation • Meet Management • June 2014 * subject to clearance by Antitrust Authority in Argentina 2013 FN Semillas* soybean seed company Buenos Aires, Argentina 2011 Soytech soybean seed company Goiânia, Goiás 2013 Wehrtec soybean seed company Cristalina, Goiás 2013 Agropastoril soybean germplasm bank Cascaval, Paraná 2010 CVR plant breeding Rio Verde, Goiás Page 155
  • 158. Strategic Progress Achieved Enhance Crop Protection & Env. Science Strengthen Customer Centricity Lead the Way in Innovation Expand Seeds Business ● €1.5bn sales in 2013 with products launched since 2006 ● Biologicals strengthened further with Prophyta and Biagro* ● Expansion of supply capacities for key active ingredients ● Support to increase productivity of small-scale farmers ● Improved channel management practices ● Broadened food chain partnership business model ● Pipeline Peak Sales Potential**  €4bn ● Increased investment in Seeds R&D ● Innovating at the interface between chemistry and biology ● Strengthened presence in Latin American soybean market ● Further investments done in wheat and vegetables ● Development of innovative traits • Bayer Investor Presentation • Meet Management • June 2014 * Clearance by Antitrust Authority in Argentina outstanding ** from products launched between 2011-2016Page 156
  • 159. • Bayer Investor Presentation • Meet Management • June 2014 2013 Sales CAGR 2016e Further Growth at Benchmark Profitability Page 157
  • 160. Global Trends in Agriculture • Bayer Investor Presentation • Meet Management • June 2014 GLOBAL FOOD PRODUCTION CLIMATE CHANGE -322 kg rice per hectare Yields under pressure +1°C FARMLAND PER CAPITA (ha) 1950 : 0.52 2010 : 0.20 2050 : 0.15 INSUFFICIENT STORAGE Up to 40% of fruit and vegetables lost in India Equivalent to the annual consumption in UK CHANGING CONSUMPTION PATTERNS Increasing demand for protein Need for a sustainable productivity increase By 2050 +70% HUNGER 1 in 8 goes hungry today POPULATION GROWTH 7 billion people on the planet today 9.6 billion people in 2050 Page 158
  • 161. Crop Commodity Prices Declined in 2013, But Are Still At Relatively High Levels • Bayer Investor Presentation • Meet Management • June 2014 Source: Bloomberg 0 500 1,000 1,500 2,000 2,500 3,000 3,500 4,000 4,500 5,000 0 100 200 300 400 500 600 700 800 900 1,000 2008 2009 2010 2011 2012 2013 2014 Soybeans (LS) Corn (LS) Wheat (LS) Canola (LS) Rice (RS) Cotton (RS) USD/ton USD/ton Page 159
  • 162. Seed and Crop Protection Market Expected to Grow  5% in 2014 • Bayer Investor Presentation • Meet Management • June 2014  In many growing regions farmer income level is healthy after 3 good years  Commodity prices still above critical threshold for farmers, triggering investment in high-value seeds and crop protection  Steady expansion of soybean farming in Latin America  Expansion of agricultural production in Asia/Pacific continues DESPITE  Prices for agricultural commodities expected to be below 2013 levels  Global stocks-to-use ratios for key crop commodities on upward trend Page 160
  • 163. Promising 2014 Outlook  We expect to grow faster than the market  We plan to raise sales by a mid- to high-single-digit percentage on a currency- and portfolio-adjusted basis We anticipate negative currency effects of about 3%  We plan to increase EBITDA before special items by a low single-digit percentage, allowing for negative currency effects of approx. €150m • Bayer Investor Presentation • Meet Management • June 2014 Outlook depends on specific planning assumptions as detailed in the Annual Report Assuming average FX rates of Q4‘13 (USD 1.36)Page 161
  • 164. CropScience – Above Market Growth at Benchmark Profitability 2013 Guidance 2014 Aspiration 2016 Sales Increase €8.8bn Mid- to high-single-digit % (neg. FX effect approx. -3%) 6% CAGR Adj. EBITDA Increase €2.2bn Low-single-digit % (neg. FX effect approx. -€150m) Adj. EBITDA Margin 25.5% - 24-25% Assuming average FX rates of Q4‘13 (USD 1.36) Sales ∆ % Fx & portf. adjusted, margin = EBITDA before special items to sales • Bayer Investor Presentation • Meet Management • June 2014Page 162
  • 165.  Increasing demand for innovative and sustainable agricultural solutions  Expansion of production capacity of for herbicide glufosinate-ammonium  Broadening seeds infrastructure for soybean and wheat  Expanding and modernizing R&D facilities  CAPEX expansion to €2.4bn for 2013 - 2016 Stepping Up Investment Plans to Fuel Future Growth • Bayer Investor Presentation • Meet Management • June 2014 Capital Expenditures (PPE only, in €m) 303 453 620 2012 2013 2014e Page 163
  • 166. Investor Handout – Meet Management Bayer MaterialScience June 2014 – New York
  • 167. MaterialScience – Leading Positions in All Segments • Bayer Investor Presentation • Meet Management • June 2014 * Aliphatic isocyanates MaterialScience €11,238m Polyurethanes €6,054m  #1-2; approx. 19-24% market share 54% 6% 23% 17% Sales in € million Polycarbonates €2,640m  #1; approx. 27% market share Coatings, Adhesives, Specialties €1,863m  #1; >40% market share* Industrial Operations €681m Sales Split by Segment 2013 Page 165
  • 168. MaterialScience – Global Production Network • Bayer Investor Presentation • Meet Management • June 2014Page 166 *Market share based on estimated sales following self-assessment # Europe, Middle East & Africa Headquarters Major Production Sites Downstream Businesses Position* Americas # 1 # 2 # 1 PUR PCS CAS Position* EMEA# # 1 # 1 # 1 PUR PCS CAS Position* Asia/Pacific # 2-3 # 1-2 # 1 PUR PCS CAS
  • 169. • Bayer Investor Presentation • Meet Management • June 2014Page 167 Automotive Other industries* Construction Furniture / Wood Electro / Electronics 19% 18% 15%21% MaterialScience – Sales By Key Customer Industries Bayer MaterialScience sales by industry in 2013 = 73% + Chemicals *Sports/leisure, cosmetics, health 10% 17%
  • 170. MaterialScience as an Integrated Solution Provider • Bayer Investor Presentation • Meet Management • June 2014Page 168 Megatrends offer business opportunities worldwide, with the emerging economies at the forefront Ongoing urbanization New and improved transportation systems Need for better energy efficiency Higher living standards Proportion of city dwellers expected to increase from 50% in 2010 to 70% in 2050* Lightweight cars New energy vehicle development High-speed rail trans- portation networks EcoConstruction with high thermal insulation standards Cold-chain efficiency Over 40m people enter the middle class every year Improved housing standards Source: Steria, The Future Report 2012
  • 171. • Bayer Investor Presentation • Meet Management • June 2014Page 169 Performance Below Expectations