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What is Acute lymphoblastic
leukemia?
Acute Lymphoblastic leukemia (ALL), is a cancer
that starts from white blood cells called lymphocytes
in the bone marrow (the soft inner part of the
bones, where new blood cells are generated).
What Causes Acute Lymphoblastic
Leukemia?
 This is not known in most cases.
However, exposure to radiation,
exposure to high voltage electric lines in
childhood and certain genetic disorders
predispose to development of ALL.
What are the Symptoms of Acute
Lymphoblastic Leukemia
 General weakness
 fatigue
 high temperature (fever)
 Weight loss
 Frequent infections
 Bruising easily or with no obvious cause
 Bleeding from the gums or nose
 A fine rash of dark red spots (called purpura)
 Blood in urine or stools
 Pain in the bones or joints
 Breathlessness
 Swollen lymph glands
 Enlarged liver or spleen
How do we Diagnose Acute Lymphoblastic
Leukemia?
 Complete Blood Count:
 Bone Marrow Examination
 Flow Cytometry
 Cytogenetics: This is testing for abnormalities in the
chromosomes.
http://www.bmthospitalindia.com/Adult-Acute-Lymphoblastic-Leukemia.html
How do we classify Acute Lymphoblastic
Leukemia to decide on the outcome?
 Age: if the patient is 2 – 10 years old, it is considered
favourable
 Cytogenetics: Certain chromosomal abnormalities
such as increase in number of chromosomes
(Hyperploidy) and translocation 12: 21 are considered
favourable.
 Response to Treatment: Response to steroids after 7
days is probably a very good indicator of how the
disease is going to behave.
How do we treat Acute Lymphoblastic
Leukemia?
 Induction Therapy
 Consolidation Therapy
 Maintenance Therapy
 Preventive treatment to the spinal cord
 Radiation Therapy
Note : Depending on patient’s evaluation, the phases of treatment
for acute lymphocytic leukemia can span two to three years.
Website : http://www.bmthospitalindia.com/Adult-Acute-Lymphoblastic-
Leukemia.html
Email : info@bmthospitalindia.com
Phone : +91-8130000120, 011-43066353
Contact us
For More Information Please
Visit us at :
Dharamshila Hospital and Research Centre,
Near New Ashok Nagar Metro
Station, Vasundhara Enclave, Delhi - 110096,
INDIA
Thank You

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What is Acute Lymphoblastic Leukemia?

  • 1. What is Acute lymphoblastic leukemia? Acute Lymphoblastic leukemia (ALL), is a cancer that starts from white blood cells called lymphocytes in the bone marrow (the soft inner part of the bones, where new blood cells are generated).
  • 2. What Causes Acute Lymphoblastic Leukemia?  This is not known in most cases. However, exposure to radiation, exposure to high voltage electric lines in childhood and certain genetic disorders predispose to development of ALL.
  • 3. What are the Symptoms of Acute Lymphoblastic Leukemia  General weakness  fatigue  high temperature (fever)  Weight loss  Frequent infections  Bruising easily or with no obvious cause  Bleeding from the gums or nose  A fine rash of dark red spots (called purpura)  Blood in urine or stools  Pain in the bones or joints  Breathlessness  Swollen lymph glands  Enlarged liver or spleen
  • 4. How do we Diagnose Acute Lymphoblastic Leukemia?  Complete Blood Count:  Bone Marrow Examination  Flow Cytometry  Cytogenetics: This is testing for abnormalities in the chromosomes. http://www.bmthospitalindia.com/Adult-Acute-Lymphoblastic-Leukemia.html
  • 5. How do we classify Acute Lymphoblastic Leukemia to decide on the outcome?  Age: if the patient is 2 – 10 years old, it is considered favourable  Cytogenetics: Certain chromosomal abnormalities such as increase in number of chromosomes (Hyperploidy) and translocation 12: 21 are considered favourable.  Response to Treatment: Response to steroids after 7 days is probably a very good indicator of how the disease is going to behave.
  • 6. How do we treat Acute Lymphoblastic Leukemia?  Induction Therapy  Consolidation Therapy  Maintenance Therapy  Preventive treatment to the spinal cord  Radiation Therapy Note : Depending on patient’s evaluation, the phases of treatment for acute lymphocytic leukemia can span two to three years.
  • 7. Website : http://www.bmthospitalindia.com/Adult-Acute-Lymphoblastic- Leukemia.html Email : info@bmthospitalindia.com Phone : +91-8130000120, 011-43066353 Contact us
  • 8. For More Information Please Visit us at : Dharamshila Hospital and Research Centre, Near New Ashok Nagar Metro Station, Vasundhara Enclave, Delhi - 110096, INDIA Thank You