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Clinical &
             Translational         BODY COMPOSITION, EXERCISE PHYSIOLOGY,
             Sciences
             Institute                     AND METABOLISM CORE
                                                         Kathleen Mulligan, PhD, Core Director
                                                                                                                                                                               UCSF
                                                                                                OVERVIEW
          SERVICES
                                   • Testing performed by specialists under appropriate medical supervision at Moffitt and SFGH Clinical
• Dual-energy X-ray
                                     Research Centers, serving all CTSI investigators
  absorptiometry (DXA) for
                                   • State-of-the art equipment and methodologies
  body composition and bone
                                   • All services offered on a cost-recovery basis for both investigator-initiated and industry-sponsored
  density testing in adults,
                                     studies in adult and pediatric populations
  children, infants
                                   • Testing available at other CTSI locations by special arrangement
• Bioimpedance analysis:           • In past year, our core supported 40 CTSI protocols (35 adult, 5 pediatric) by 36 principal investigators,
  single and multi-frequency         including 10 fellows/junior faculty
• BodPod© air displacement
  plethysmography (Moffitt)
• Anthropometry                                                                                             EXAMPLES OF ASSESSMENTS
• Treadmill testing
• Cycle ergometry
                                           OUR TEAM
• Exercise testing with full EKG
  monitoring
• Peak or max VO2                                                                                                                Infant DXA
                                                                                                                                                               Spine         Hip       Forearm
                                                                                                                                                                    DXA for bone density
• Resting energy expenditure                                                                                                 (body composition)

  by indirect calorimetry                                                       Dual energy x-ray        Whole-body DXA
                                                                              absorptiometry (DXA)      (body composition)
• 6-minute walk test, gait               John Duda, RN
  speed, stair climb, grip            Moffitt Lab Manager
  strength
• Spirometry (Moffitt)
• Activity monitoring
• Ultrasound equipment                                                                                   Anthropometry
                                                                                                                                        Indirect calorimetry
                                                                                                                                                                                   VO2 max

  available (Moffitt)                                                                                                                  during glucose clamp
                                                                                  BodPod
• Other testing as required
• Consulting                                                                                           A FEW EXAMPLES OF RECENT STUDIES
                                         Viva Tai, RD, MPH
• Training study personnel in           DXA specialist (SFGH)                          •   Body composition and exercise capacity in rheumatoid arthritis and lupus
  simple procedures                                                                    •   Metabolic impact of fructose restriction in obese children
                                                                                       •   Effects of tenofovir and other antiretrovirals on bone density (HIV+ and HIV-negative)
• Assistance with grant                                                                •   Home-based exercise program in children with cystic fibrosis
  preparation, data                                                                    •   Frailty and functional capacity in patients undergoing lung transplant
  interpretation                                                                       •   Paleolithic diet in type 2 diabetes mellitus
                                                                                       •   Visceral adiposity, HIV, and HCV: biologic mediators of hepatic steatosis
• Referrals to UCSF groups for                                                         •   Bone density in hepatitis
  other services (e.g. heavy       For further information, please contact:            •   Metabolic effects of sleep deprivation
                                           Kathleen Mulligan, PhD                      •   Levofloxacin in cystic fibrosis
  water analysis, imaging)               kathleen.mulligan@ucsf.edu                    •   Effects of HIV and menopause on musculoskeletal health
                                                                                       •   Novel interventions to reduce stress induced non-homeostatic eating
                                                                                       •   Effects of gastric bypass surgery on calcium metabolism in the spine

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Body Composition, Exercise Physiology, & Metabolism Core at the University of California, San Francisco

  • 1. Clinical & Translational BODY COMPOSITION, EXERCISE PHYSIOLOGY, Sciences Institute AND METABOLISM CORE Kathleen Mulligan, PhD, Core Director UCSF OVERVIEW SERVICES • Testing performed by specialists under appropriate medical supervision at Moffitt and SFGH Clinical • Dual-energy X-ray Research Centers, serving all CTSI investigators absorptiometry (DXA) for • State-of-the art equipment and methodologies body composition and bone • All services offered on a cost-recovery basis for both investigator-initiated and industry-sponsored density testing in adults, studies in adult and pediatric populations children, infants • Testing available at other CTSI locations by special arrangement • Bioimpedance analysis: • In past year, our core supported 40 CTSI protocols (35 adult, 5 pediatric) by 36 principal investigators, single and multi-frequency including 10 fellows/junior faculty • BodPod© air displacement plethysmography (Moffitt) • Anthropometry EXAMPLES OF ASSESSMENTS • Treadmill testing • Cycle ergometry OUR TEAM • Exercise testing with full EKG monitoring • Peak or max VO2 Infant DXA Spine Hip Forearm DXA for bone density • Resting energy expenditure (body composition) by indirect calorimetry Dual energy x-ray Whole-body DXA absorptiometry (DXA) (body composition) • 6-minute walk test, gait John Duda, RN speed, stair climb, grip Moffitt Lab Manager strength • Spirometry (Moffitt) • Activity monitoring • Ultrasound equipment Anthropometry Indirect calorimetry VO2 max available (Moffitt) during glucose clamp BodPod • Other testing as required • Consulting A FEW EXAMPLES OF RECENT STUDIES Viva Tai, RD, MPH • Training study personnel in DXA specialist (SFGH) • Body composition and exercise capacity in rheumatoid arthritis and lupus simple procedures • Metabolic impact of fructose restriction in obese children • Effects of tenofovir and other antiretrovirals on bone density (HIV+ and HIV-negative) • Assistance with grant • Home-based exercise program in children with cystic fibrosis preparation, data • Frailty and functional capacity in patients undergoing lung transplant interpretation • Paleolithic diet in type 2 diabetes mellitus • Visceral adiposity, HIV, and HCV: biologic mediators of hepatic steatosis • Referrals to UCSF groups for • Bone density in hepatitis other services (e.g. heavy For further information, please contact: • Metabolic effects of sleep deprivation Kathleen Mulligan, PhD • Levofloxacin in cystic fibrosis water analysis, imaging) kathleen.mulligan@ucsf.edu • Effects of HIV and menopause on musculoskeletal health • Novel interventions to reduce stress induced non-homeostatic eating • Effects of gastric bypass surgery on calcium metabolism in the spine