2. Objectives
• Review initial care, principles of closure
debridement, and timing of soft tissue
coverage
• Methods of coverage
– Open
– Primary vs. Secondary
– Skin grafting
– Flap
• Options for specific sites
6. Wound Excision- Debridement
• In OR, ideally
within 6-8 hours
after injury
• Tourniquet control
• Devitalized skin
and fascia excised
• Devitalized bone
fragments removed
7. Initial Management After
Debridement
• Restore vascularity
• Stabilize skeletal injury
• Repair nerves
• Repair musculotendinous units
• PLAN reconstruction
– preferably within 7 days of injury
– or following adequate control of infection
chronic cases
8. Hierarchy of Wound Closure
Methods Types
Direct closure
Skin Grafts
Local and Regional Flaps
Distant Pedicle Flaps
Free Flaps
Primary
Secondary
STSG
FTSG
Random
Axial
Random
Axial
(See next slide)
11. STSG
• Advantages
– May be meshed
– Large area
– Require less
revascularization
– Temporary
coverage
• Disadvantages
– Poor cosmesis
– Limited durability
– Contracts over time
– Donor site
problems
• Pain
• Infection
12. FTSG
• Advantages
– No wound
contracture
– Increased
sensibility
– Increased durability
– Better cosmesis
– Primary closure of
donor site
• Disadvantages
– Longer to
revascularize
– Cannot mesh
– Recipient site must
have rich
vasculature
13. Wound Preparation for Grafts
• Vascularity
• Hemostasis
• Debride all
necrotic tissue
• Optimize
co-morbid
conditions
14. Donor Site Selection
• STSG
– 0.015 inches thick
(thickness #15
scalpel)
– Lateral buttock
– Ant. and Lat. Thigh
– Lower abdomen
– Avoid medial thigh
and forearm
• FTSG
– Depends on area to
be covered
– Large grafts-lower
abdomen and groin
– Small- medial
brachium and volar
wrist crease
– Plantar skin from
instep
15. Skin Harvest for STSG
• Sterile preparation
• Cleanse with
alcohol to remove
residue
• Lubricate
• Set depth
• Traction with
tongue blade
16. Skin Harvest for FTSG
• Use template
• Cut out ellipse
• Defat after harvest
• Apply and
compress with
moist bolster
17. Donor Site Care
• Open
• Semi-open
• Semi-occlusive
• Occlusive
• Biologic
18. Indications for Flap Coverage
• Skin graft cannot be used
– Exposed cartilage, tendon (without paratenon),
bone, open joints, metal implants
• Flap coverage is preferable
– Secondary reconstruction anticipated, flexor
joint surfaces, exposed nerves and vessels,
durablitiy required, multiple tissues required,
dead space present
19. Classification of Soft Tissue
Flaps
• Random
• Axial
• Local
– Advancement
– Rotation
• Distant
– Direct
– Tubed
– Free
20. Classification of Soft Tissue
Flaps
• Direct cutaneous
• Musculocutaneous
• Septocutaneous
21. Direct Cutaneous Flaps
• Groin flap-
superficial
circumflex iliac
artery
• Deltopectoral flap-
2nd and 3rd
perforating br. Of
int thoracic artery
23. Musculocutaneous Flaps
Mathes Classification
• Type II- one dominant
vascular pedicle close
to insertion with
additional smaller
pedicles entering
along the course of the
muscle
– Brachioradialis
– Gracilis
– Soleus
Type II: gracilis
25. Musculocutaneous Flaps
Mathes Classification
• Type IV- multiple
pedicles of similar
size
– Generally of less
use in
reconstruction than
single or double
pedicled muscles
Type IV: Sartorius
26. Musculocutaneous Flaps
Mathes Classification
• Type V- one
dominant pedicle
and several smaller
segmental vascular
pedicles
– Latissimus Dorsi
– Pectoralis major
Type V: Latissimus Dorsi
28. Septocutaneous Flaps
Cormack, et. al
• Type B-based on
single fasciocutaneous
perforator of moderate
size consistent in
presence and location
• Parascapular flap-
circumflex scapular artery
• Saphenous artery flap
• Lateral thigh flap- 3rd
profunda perforator
29. Septocutaneous Flaps
Cormack, et. al
• Type C- supported by
multiple perforators
which pass from a
deep artery thru a
fascial septum
• Radial forearm flap
• Posterior Interosseous flap
30. Septocutaneous Flaps
Cormack, et. al
• Type D -type C
septocutaneous flap
removed in continuity
with adjacent muscle
and bone to create a
osteo- myo-
fasciocutaneous flap
• Free fibula osteocutaneous
flap
31. Principles of Free Tissue
Transfer
• Pre-operative Assessment
– Physical Examination
– Vascular Status
– ??Arteriogram
– Alternative methods
– Choice of donor site
• Length and width necessary to fill defect
• Vascular pedicle length
• Innervated or composite with bone
32. Principles of Free Tissue
Transfer
• Surgical Considerations
– Team approach
– Comfortable setting
– Anesthesia- regional block/ epidural
– Temperature
– Volume replacement
– Careful surgical technique
– PREVENT SPASM
33. Principles of Free Tissue
Transfer
• Post-operative Management
– ICU for monitoring
– Maintain body temperature
– Fluid balance
– Good pain relief
– Monitoring flap- temperature, doppler,
photoplethysmography
38. Soft Tissue Coverage for the
Tibia
• When treating limbs with severe underlying
osseous injury (ASIF/ OTA type C), use of
a free flap for soft tissue coverage was less
likely to have a wound complication than
use of a rotational flap, regardless of
location.
Pollack, et.al., JBJS 82-A: 1681-1691, 2000
39. Soft Tissue Coverage for the
Tibia
• Timing: best result obtained with early soft
tissue coverage (< 7 days) for Gr III-B open
tibial fractures,
• To encourage fracture healing, muscle flaps
are superior to local skin flaps
40. Soft Tissue Coverage of the
Ankle/ Foot
• Open wounds in this area remain a
challenge
• Donor site options
• Medial plantar flap for reconstruction of the
heel
• Abductor hallucis flap
• Flexor digitorum brevis
General References
Serafin, Donald M.D.: Atlas of Microsurgical Composite Tissue Transplantation. W.B. Saunders Company, 1996.
Webster, Martyn H. C. MBChB, FRCS (Glasg.), Soutar, David S. MBChB, FRCS (ED.): Practical Guild to Free Tissue Transfer. Butterworth & Co, 1986.
McCraw, John B. M.D., F.A.C.S., Arnold, Phillip G. M.D., F.A.C.S., et al: McCraw and Arnold’s Atlas of Muscle and Musculocutaneous Flaps, Hampton Press Publishing Co.,1986.
Cormack, George C. MA, MB, ChB, FRCS(ED), Lamberty, B. George H. MA, MB, BChir, FRCS: The Arterial Anatomy of Skin Flaps. Churchill Livingstone, 1986.
Moy, Owen J. M.D., et al: Soft Tissue Management of Complex Upper Extremity Wounds. W.B. Saunders Company, 13-2: 163-318, May 1997.
Objectives of this talk are as stated.
Options for coverage will be discussed for the tibia, foot, elbow and hand. More proximal sites such as the shoulder and hip are generally covered with rotation flaps if skin grafting is not adequate.
Evaluation of the injured extremity should begin with a targeted and thorough history and physical examination. With regard to history, all details listed should at a minimum be taken into account. If there is vascular compromise, the time from injury takes a higher precedence. In upper extremity injuries, hand dominance is important to know.
The physical exam should be systematic including an evaluation of all these components. If the injured extremity is dysvascular, restoration of circulation becomes a treatment priority if salvage is anticipated. The extent of injury, depth and size of the wound and degree of contamination should be ascertained at the initial debridement, however, the degree of tissue viability may not be readily apparent and may require several debridements before a final determination can be made.
Tetanus prophylaxis
Debridement should be carried out promptly, ideally within 6-8 hours from the time of injury to lessen the chance of infection. All devitalized skin, fascia, and bone should be removed, hence the term wound excision.
Picture of dorsal soft tissue avulsion injury of the hand from roll-over MVA. Injury will require wound excision and eventually reconstruction of extensor tendons and coverage with some type of vascularized tissue (flap).
Obviously if injured extremity is dysvascular at initial presentation, the priority of treatment is to restore the vascularity, however, a quick debridement of obviously dead and contaminated tissue should be carried out while preparing for revascularization. The choice of restoring vascularity or stabilizing the fracture should be made in conjunction with the vascular surgeon and in most circumstances will be dictated by the ischemic time of the injured extremity.
In general, soft tissue coverage of an injured extremity should be performed using the simplest and most reliable method taking into account the size and extent of the injury and the expertise of the surgeon. A stepladder approach should be considered starting with the easiest method. Obviously, direct closure either by primary or secondary means would be the simplest means of obtaining closure. If this cannot be accomplished, skin grafting should be considered followed by local/ regional flaps, distant pedicled flaps and finally free flaps.
The ability to move tissue from one area of the body to an entirely different area has revolutionized methods of soft tissue coverage. Free tissue transfer is now an established and reliable method for reconstructive surgery, however, microsurgical skills are a prerequisite, as a minimum of one arterial and one venous anastomosis are required for successful transfer of soft tissue as free flap. Free flaps are classified by the type of tissue being transferred. For example, if a latissimus muscle is transferred with a paddle of skin it would be classified as a free latissimus musculocutaneous flap. A radial forearm flap is transferred with skin and fascia and therefore would be classified as a free radial forearm fasciocutaneous flap.
Skin grafting is the simplest form of coverage. This graft by definition is non-vascularized and requires capillary in growth from the recipient tissue being covered for the dermal elements of the graft to survive The graft may be harvested as a split thickness or full thickness graft. In general, most wounds on injured extremities are covered with STSG’s. Small areas or wounds on the volar side of the hand are generally covered with a FTSG. Critical areas of the sole of the foot may also benefit from FTSG.
Advantages and disadvantages of STSG as listed. Split grafts may provide a “biologic” dressing over critical structures such as nerve, vessels, tendon or bone while awaiting definitive (free tissue) coverage preventing dessication.
Advantages and disadvantages of FTSG’s as listed
In order for a skin graft to survive, the wound to be covered must be prepared. The surface to be covered must contain a capillary bed capable of ingrowth. Bleeding must be controlled meticulously. A hematoma which forms under a graft will prohibit capillary ingrowth which is a frequent cause of failure. All necrotic tissue must be thoroughly debrided. A quantitative tissue culture may be a useful tool for determining graft-bed suitability, especially in cases of gross contamination. Systemic medical conditions and nutritional status must be optimized prior to graft placement.
The goal of harvesting donor tissue is to approximate the appearance and durability of the original tissue while causing minimal morbidity at the donor site. The thicker the graft the more donor site morbidity.
Numerous power dermatomes are available for harvesting STSG’s Generally the width of the dermatome is set to the thickness of a #15 scalpel blade. When just the bevel fits, the thickness will be .01 inches. When the entire blade fits, the thickness will measure .0115 inches. It is important to lubricate the undersurface of the dermatome to allow it to smoothly advance. By providing traction to the skin surfaces, the skin surface flattens allowing the dermatome to function more efficiently.
Most areas can be safely covered by a STSG, however, the palm of the hand is probably best covered with a FTSG. Prior to suturing the FTSG it is important to defat the graft which is best done with a pair of sharp scissors. Do not scrape the fat of with a scalpel because this will cause unnecessary damage to the dermis. Suturing a moist bolster over the graft will keep it adherent to the underlying recipient bed and encourage capillary ingrowth.
There are several techniques for managing the donor site. For STSG’s the dermis is covered with regenerated epithelium in 7-14 days.
Leaving the wound open to air can be accomplished after hemostasis has been obtained using a fine mesh gauze saturated with lidocaine containing a 1:200,000 epinephrine solution which is left in place for 10 min. until a fibrin layer develops. Disadvantage is that it is painful during the 1st 24 hrs until the wound dries.
Fine mesh gauzes are considered semi-open and allow for egress of fluid and bacteria from the wound. Disadvantage is pain when removing the adherent gauze. Biobrane is a composite of a silicone membrane and flexible nylon fabric covalently bonded to porcine collagen peptides which diminishes the adherence and lessens the pain with removal. Disadvantage is the expense of the product.
Opsite and Tegaderm are considered semi-occlusive dressings because the are vapor permeable and bacteria and liquid impermeable. Disadvantage: seromas may develop under the material and increase the risk of infection.
Duoderm is completely occlusive. Exudate is more acidic which potentially limits bacterial growth
Excess skin graft or porcine xenografts can be used as a biologic dressing but may not be practical in most situations.
For FTSG’s primary closure should be performed if possible.
There are two general indications for performing soft tissue coverage with a flap which are listed on this slide .
There are several classifications for soft tissue flap.
McGregor (1972) introduce the concept of random and axial flaps. A random flap is one that lacks any significant bias in its vascular pattern. Without a definitive recognized arteriovenous system, elevation of the flap is generally restricted, that is the length of the flap to be raised should be no greater than the width of the base of the flap which is providing the necessary blood flow thru the sub-dermal plexus. There are several techniques for extending the length of random flaps. One such technique is known as delay where parallel incisions are created and the base of the flap is undermined and then sutured back in place for a period of about 2-3 weeks. The blood flow is then “channeled” and thus allow extension of the flap margin beyond the 1:1 ratio.
An Axial pattern flap is single pedicled flap that has an anatomically recognized arteriovenous system running along its long axis. An axial pattern flap is not restricted to the same 1:1 ratio of flap elevation.
Flaps may also be classified as either local or distant on the basis of their proximity of the donor site to the recipient site. Local flaps can be further categorized by the nature of their pedicle into advancement or rotation flaps.
As the knowledge of skin vascularity has increased, the incorporation of tissues other than skin and subcutaneous tissues in the coverage of more substantial defects has become more successful By default, a nomenclature system has developed based on flap composition. The terms cutaneous, fasciocutaneous and myocutaneous are used to describe the incorporation of skin, fascia, or muscle. Eventually, other structures such as bone, nerve and tendon have been incorporated into the flap. These are known as compound flaps.
Since most flaps are designed around the tissue’s vascular pedicle, perhaps the most justified method of classification is one based on the flap’s vascular origin. It is now accepted that there are three basic patterns of blood supply:
Direct cutaneous
Musculocutaneous
Septocutaneous
Each of these flaps will be discussed on the following slides.
The direct cutaneous flap has arteries that run immediately above the muscle and fascia in the subdermal fat with a specific directional orientation. An excellent example is the direct cutaneous flap is the groin flap which is supplied by the superficial circumflex iliac artery.
Muscle flaps have been categorized by Mathes. (Clinical Applications for Muscle and Musculocutaneous Flaps. St. Louis, Toronto, London; CV Mosby, 1982, pp3-27)
Musculocutaneous flaps have been categorized according to the five muscle types depending on their vascular anatomy. Each pattern has significance for arc of rotation skin territory , whether it can be elevated as a distally based flap and whether it can be elevated as a free flap.
A type I flap has one dominant pedicle. They cannot be raised as distally based rotation flaps because there are no secondary vessels perforating distally. Examples are listed.
Mathes, Clinical Applications for Muscle and Musculocutaneous Flaps. Mosby 1982
These flaps can be raised as free flaps based on the dominant proximal vessel or as distally based rotation flaps based on the smaller pedicles entering along the course of the muscle. Examples are listed. The BR is based on a dominant perforator off the radial artery in the mid-substance of the muscle. The Gracilis is supplied by the ant. Br of the obturator artery. The soleus is supplied by a branch off the post. tibial artery.
Mathes, Clinical Applications for Muscle and Musculocutaneous Flaps. Mosby 1982
A type III flap has two dominant vessels which allows for rotation from either end. The rectus abdominis flap is supplied by the deep inferior epigastric artery, which is the dominant vessel and will reliably supply the entire muscle. The superior epigastric artery will reliably supply the upper two-thirds of the muscle .
The gluteus maximus is supplied by both the superior and inferior gluteal arteries. The inferior gluteal vessel is dominant but an excellent intramuscular vascular connection allow the gluteus to be supplied by either vessel. These vessels are separated by the piriformis muscle as they exit the pelvis.
Mathes, Clinical Applications for Muscle and Musculocutaneous Flaps. Mosby 1982
Type IV muscles are generally not used for soft tissue reconstruction because they lack a distinct pedicle and cannot be rotated reliably on the small perforating branches.
Mathes, Clinical Applications for Muscle and Musculocutaneous Flaps. Mosby 1982
The type V flaps have a dominant pedicle which allows them to elevated as a free flap or rotation flap. Since there is segmental blood supply to the muscle at the distal end, half the muscle can be harvested on the dominant pedicle while the remainder of the muscle is nourished from the segmental vascular pedicles.
The latissimus dorsi which is the “workhorse” muscle flap for soft tissue coverage is an example of a type V muscle
Mathes, Clinical Applications for Muscle and Musculocutaneous Flaps. Mosby 1982
Septocutaneous flaps have arteries which traverse between the overlying muscles in distinct intermuscular septae and therefore are known as septocutaneous vessels. Septocutaneous flaps are classified into 4 types based on the location and number of the vascular pedicles as well as flap composition
A Type A flap is a pedicled flap containing fascia and skin that depends on multiple fasciocutaneous perforators at the base and that is oriented with the long axis of the flap at the level of the deep fascia
This is a pedicled or free flap depending upon a single and consistent fasciocutaneous perforator off an artery feeding a plexus at the level of the deep fascia. The sural artery fasciocutaneous flap is supplied by the last perforator of the peroneal artery which can be found approximately 5-7 cm above the lateral malleolus. The parascapular flap is based on the parascapular br of the circumflex scapular artery. Remember, these flaps are all supplied by well defined perforating vessels.
Shown is a picture of a distally based sural artery flap with the pedicle easily visualized.
A Type C flap is supported by multiple small perforators along its length which reach it from a deep artery by passing along a fascial septum. The radial forearm flap was one of the first of of this type to be described.
This is a compound flap which incorporates other structures such as muscle and bone. A radial forearm flap can be raised with a half the diameter of the radius. Another example of this flap is the fibula osteocutaneous flap
A complete physical examination is essential with particular importance given to the vascularity of the injured extremity. The absence of suitable vessels is a contraindication for free tissue transfer. A careful clinical evaluation by palpating peripheral pulses and occluding vessels distally is often sufficient. Noninvasive studies such as doppler evaluation is useful. However if there is significant ASPVD or significant trauma to the extremity, further evaluation with an arteriogram should performed. Simpler, alternative measures should always be considered prior to embarking on free tissue transfer. The choice of donor site is ever-increasing and is dependent on a number of factors such as the length and width of the pedicle , the thickness of the flap, and whether sensory reinnervation or composite tissue is desired. Finally, and the surgeon’s own experience with a particular flap will be an important factor to consider.
Performing a free tissue transfer is a complex task that requires a team approach from the surgeon, assistant surgeon, anesthesiologist and the nursing personnel. The room should be comfortable and familiar with the surgeons sitting in a relaxed position. Many advances have been made in anesthesia, particularly regional anesthesia which may have a role in promoting vasodilation of the vessels and minimizing spasm.
Temperature should be closely monitored and maintained throughout the procedure. A reduction in the circulating volume will cause a reflex vasoconstriction and therefore, it is vital to fluids need to be replaced prior to losses.
Careful surgical technique goes without saying. The majority of failures can be attributed to poor technique. Spasm can be a very difficult problem. Ways to control spasm involve items discussed above as well as direct application of a local anesthetic(4%lidocaine) or verapamil hydrochloride.
Strong consideration should be given to monitoring these patients for the first 24-48 hours in the ICU where body temperature, fluid balance and pain relief can be monitored closely. Monitoring the flap post-operatively is very much surgeon dependent. Several of the methods are listed but such technology should not replace good sound clinical judgement such capillary refill, color, and turgor. If thrombosis is suspected early exploration is essential if the free tissue transfer is to be saved.
Conventional teaching for soft tissue coverage of the tibia
Medial head of Gastrocnemius based on the sural artery (branch from the popliteus) is a proximally based flap that can be rotated to cover proximal 1/3 defect of the tibia. Can also be used in the distal femur and knee. Careful release of the origin preserving the artery can provide additional length as can crosshatching the fascia.
There are seldom local flap coverage options for defects in the distal 1/3 of the leg. Generally free flaps are required as demonstrated above (latissimus dorsi free flap).
Local tissue flaps are frequently compromised during the accident and should be used with caution in the acute post traumatic setting.
Coverage of defect in some areas of the ankle and foot remain a challenge to reconstructive surgeons. The difficulty comes from the limited mobility and availability of the overlying skin, the unique weight-bearing requirements and the relatively poor circulation of the skin. Possible reconstructive options include local distant and free flaps. Local flap reconstruction remains popular because it is a simple reliable one-stage procedure. Options include the medial plantar flap which is the best option for coverage overlying the exposed calcaneus. Other smaller flaps include the Abductor hallucis and flexor digitorum flap are helpful for covering small defects but have limited use because of their small arc of motion.
In the past a defect such as this might require a free flap to obtain coverage of this wound with exposed hardware. With larger soft tissue defects around the ankle and foot, an increasingly popular method among reconstructive surgeons is the use of a distally based sural artery flap. This flap has the advantage of being easy and quick to elevate and there is no microvascular anastamosis required. It is reliably supplied by the most distal perforating artery of the peroneal artery which is located approximately 5-7 cm above the tip of the lateral malleolus.
Another large soft tissue defect which was covered with a sural artery flap
As stated
There are a number of regional and pedicled flaps which can be used to gain coverage of elbow wounds. Listed on this slide are some of the flaps one might consider.
Severe open fracture dislocation of the elbow as a result of a blast injury from a tire explosion. After irrigation/ debridement and ORIF the proximal ulna fracture and plate were exposed requiring coverage with a flap. Because of the extent and the injury, a free latissimus flap was chosen.
When wound closure cannot be obtained by primary means, flexor and extensor tendons are not exposed and there are no plans for subsequent reconstructive procedures then STSG can be used for the dorsum of the hand and generally FTSG is used for the palm of the hand. My personal preference with regard to STSG is to apply them as a sheet without meshing.
An in-depth discussion on soft tissue coverage of the hand is beyond the scope of this lecture but listed are common flaps that are used that the general orthopaedic surgeon should be familiar with.
Cross finger flap covers volar defects on ;the finger from an adjacent digit
Thenar flap- provides coverage to the IF/ MF fingertip. Generally it is not a good choice for the elderly patient because of flexion contractures of the PIPJ
Radial Forearm Flap is a common flap use for soft tissue avulsion injuries, particularly for the dorsum of the hand. Must ensure that the hand has a complete arch by performing either non-invasive doppler evaluation or arteriogram if there is a question.
Posterior Interosseous Flap is gaining more popularity as a retrograde flap. The post. Interosseous artery is found between the EDQ and ECU and the nerve to the ECU from the PIN may limit its elevation.
The groin flap is still an excellent method of obtaining coverage over the back of the hand and first web space. The disadvantage is that it is bulky and may require subsequent operations to defat the flap.
Dorsal soft tissue avulsion injuries are a common injury in rollover motor vehicle accidents oftentimes requiring extensor tendon reconstruction. There are several methods for obtaining coverage over the dorsum of the hand such as shown with this radial forearm flap. Groin flaps and free flaps such as the temporal mandibular flap and lateral forearm flap have been use for soft tissue coverage of the dorsum of the hand.