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Corporate Responsibilities for
    the Right to Health

           16th Cochrane Colloquium
              Freiburg im Breisgau
               October 6th, 2008




            Klaus M. Leisinger
 Novartis Foundation for Sustainable Development
Who defines Corporate Responsibilities today?

                                                       Business                                 Environment
                                                        Ethics                                                      Labor Standards
                          Pandemics                                                Mass media


                                                Pressure                                                   Local
                                                 groups                                                 communities      Human Rights
                                                                   Shareholders          Employees

                  Public Health
                                                                                                                         Healthcare Policies
                                                   Corporate
                                                                                                        Patients
                                                  management

          Clinical                 Political                                                                         Private      Pricing
          Trials                   parties                                     Company                               sector


                                                    Physicians                                        Governments              Marketing
                                                                                                                               Practices
       Drug / patient safety
                                                                                                                        Access to Medicines
                                                                    Pharmacists           Suppliers
                    Neglected                  Customers                                                Organizations
                    Diseases
                                                                                                                        Aging
                                                                                   Science &    Patents
                                          Right to Health                          Academia

Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The Request of the UN Global Compact




          Human Rights
          The Secretary-General asked the world business community to

          Principle 1:
          support and respect the protection of the international
          human rights within their sphere of influence;

          Principle 2:
          make sure their own corporations are not complicit in
          human rights abuses;




Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The Preamble
                     of the Universal Declaration of Human Rights




               THIS UNIVERSAL DECLARATION OF HUMAN RIGHTS (has been
               proclaimed) as a
               “common standard of achievement for all peoples and all
               nations, to the end that every individual and every organ of
               society, keeping this Declaration constantly in mind, shall strive by
               teaching and education to promote respect for these rights and
               freedoms and by progressive measures, national and
               international, to secure their universal and effective
               recognition and observance, both among the peoples of Member
               States themselves and among the peoples of territories under their
               jurisdiction.” (excerpt from Preamble)


Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The Right to Health




                                            Universal Declaration of Human Rights
        Article 25.
        (1) Everyone has the right to a standard of living adequate for the
        health and well-being of himself and of his family, including food,
        clothing, housing and medical care and necessary social services,
        and the right to security in the event of unemployment, sickness,
        disability, widowhood, old age or other lack of livelihood in
        circumstances beyond his control.
        (2) Motherhood and childhood are entitled to special care and
        assistance. All children, whether born in or out of wedlock, shall enjoy
        the same social protection.


Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
International Covenant on Economic, Social and Cultural
                           Rights
                  Article 12
                  1. The States Parties to the present covenant recognize the right of
                      everyone to the enjoyment of the highest attainable standard of
                      physical and mental health.
                  2. The steps to be taken by the States Parties to the present Covenant to
                      achieve the full realization of this right shall include those necessary
                      for:
                  (a) The provision for the reduction of the stillbirth-rate and of infant
                      mortality and for the healthy development of the child;
                  (b) The improvement of all aspects of environmental and industrial
                      hygiene;
                  (c) The prevention, treatment and control of epidemic, endemic,
                      occupational and other diseases;
                  (d) The creation of conditions which would assure to all medical service
                      and medical attention in the event of sickness.
Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The Requests of the Special Rapporteur, e.g.

            Pharmaceutical companies should, whenever formulating and
            implementing its strategies, policies, programmes, projects and activities
            that bear upon access to medicines:


                 −        give particular attention to disadvantaged individuals and
                          communities, such as those living in poverty;
                 −        give particular attention to gender-related issues;
                 −        give particular attention to the needs of children;
                 −        give particular attention to the very poorest in all markets;
                 −        be transparent;
                 −        encourage and facilitate the participation of all stakeholders,
                          including disadvantaged individuals and communities.
                 (guidelines 6(i)-(vi))

Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The societal return on pharmaceutical investment

                                                                                     0%
 80                                                                                            Heart           Cancer          Stroke       All causes
                                                                                              Disease


 75
                                                   Females                          -10%


                                                                                                                               -15%           -14%
 70                                  Males
                                                                                    -20%                       -19%
                                                      US life expectancy
                                                              Years at birth                              Drop in death rates 1990-2000 among
 65                                                                                            -27%       US pop. 45-64
  1960                              1970       1980        1990              2000   -30%
                                                                                       20
        26.%1503 19.7%
               0%51982 19




30%
                            26.2%

                                                                                      15
                                           19.7%
20%
                                                                                      10

10%                                                      US pop. > 65                            Average length of stay in
                                                                                       5
                                                         with disability                         patient days
0%                                                                                     0
                            1982           1999                                        1960             1970            1980            1990             2000


Sources:        OECD Health Data 2004; Health, United States, 2003: Chartbook on Trends in the Health of Americans; Manton KG, Gu X.,   Proc Natl
Acad Sci USA 2001 May 22; 98(11):6354-9.

 Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Measuring misery


  About 2.5 billion people live on less than
  USD 2 a day;

  The richest 20% of the world’s population
  receive 85% of the global income, the
  poorest 20% only 1.4%

  Average life expectancy in the poorest
  countries of Africa is less than 45 years

  Every year more than 500 000 women die
  in pregnancy and childbirth – one every
  minute

  14 million children die every year due to
  preventable diseases


Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
The “difficult” Corporate Responsibility challenges
                        Market failures and failing states

      •                  Who is in charge if markets fail to help cope with poverty
                         diseases or if those that are supposed to be in charge are
                         not delivering – because they are not capable or willing?
      •         Under which conditions can a business enterprise be
          expected to do what for whom until when?
      •                  How much is enough? What is “appropriate” in a world with
                         2.5 billion people living in absolute poverty? Who has the
                         legitimacy to determine the “right amounts”?
      •                  Under which conditions is it legitimate to conduct clinical trials in
                         developing countries?
      •                  etc.




Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Corporate Responsibility Tools for
                                         the „Access to Medicine“


  Differential Pricing;
  Licensing for market failure;
  Corporate Philanthropy incl. Donations;
  Pro Bono Research;
  Screening of Patent Library;
  Program Co-operation with Development Institutions
  Management Support (Human Resources, Logistics, etc.)
  Other innovative and creative private sector skills and methods.




Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Novartis is known as a leader in drug access efforts


         Leprosy (free to WHO1):
         Over four million patients treated since 2000

         Malaria / Coartem:
         66 million treatments delivered in 2007
                                                                                   Access programs
         Tuberculosis (with WHO):                                                  worth USD 950
         500 000 free treatments provided over five years                          million reached
                                                                                   66 million
                                                                                   patients in 2007
         Glivec2 Patient Assistance Program:
         Free therapy to 27 000 people in 80 countries

         Novartis Institute for Tropical Diseases:
         Singapore-based research initiative


          1
                  World Health Organization
          2
                  Gleevec in US


Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Why bother with Access to Medicines issues?




    Because it is the right thing to do:

    You cannot have a first class economic performance and be
    perceived not to care about preventable mortality and morbidity.




Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
Plausible arguments for a “Business Case”

Applied Corporate Responsibility for Access to Medicines is likely to

 Save Lives and prevent morbidity by providing innovative solutions;
 Be “part of the solution” of one of the most difficult social issues;
 Engender employees’ motivation and identification;
 Enhance the attraction of the corporation as a partner for
      cooperation, ethical investment, excellent people, and critical
      customers).




 Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only

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Corporate responsibility for the right to health

  • 1. Corporate Responsibilities for the Right to Health 16th Cochrane Colloquium Freiburg im Breisgau October 6th, 2008 Klaus M. Leisinger Novartis Foundation for Sustainable Development
  • 2. Who defines Corporate Responsibilities today? Business Environment Ethics Labor Standards Pandemics Mass media Pressure Local groups communities Human Rights Shareholders Employees Public Health Healthcare Policies Corporate Patients management Clinical Political Private Pricing Trials parties Company sector Physicians Governments Marketing Practices Drug / patient safety Access to Medicines Pharmacists Suppliers Neglected Customers Organizations Diseases Aging Science & Patents Right to Health Academia Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 3. The Request of the UN Global Compact Human Rights The Secretary-General asked the world business community to Principle 1: support and respect the protection of the international human rights within their sphere of influence; Principle 2: make sure their own corporations are not complicit in human rights abuses; Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 4. The Preamble of the Universal Declaration of Human Rights THIS UNIVERSAL DECLARATION OF HUMAN RIGHTS (has been proclaimed) as a “common standard of achievement for all peoples and all nations, to the end that every individual and every organ of society, keeping this Declaration constantly in mind, shall strive by teaching and education to promote respect for these rights and freedoms and by progressive measures, national and international, to secure their universal and effective recognition and observance, both among the peoples of Member States themselves and among the peoples of territories under their jurisdiction.” (excerpt from Preamble) Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 5. The Right to Health Universal Declaration of Human Rights Article 25. (1) Everyone has the right to a standard of living adequate for the health and well-being of himself and of his family, including food, clothing, housing and medical care and necessary social services, and the right to security in the event of unemployment, sickness, disability, widowhood, old age or other lack of livelihood in circumstances beyond his control. (2) Motherhood and childhood are entitled to special care and assistance. All children, whether born in or out of wedlock, shall enjoy the same social protection. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 6. International Covenant on Economic, Social and Cultural Rights Article 12 1. The States Parties to the present covenant recognize the right of everyone to the enjoyment of the highest attainable standard of physical and mental health. 2. The steps to be taken by the States Parties to the present Covenant to achieve the full realization of this right shall include those necessary for: (a) The provision for the reduction of the stillbirth-rate and of infant mortality and for the healthy development of the child; (b) The improvement of all aspects of environmental and industrial hygiene; (c) The prevention, treatment and control of epidemic, endemic, occupational and other diseases; (d) The creation of conditions which would assure to all medical service and medical attention in the event of sickness. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 7. The Requests of the Special Rapporteur, e.g. Pharmaceutical companies should, whenever formulating and implementing its strategies, policies, programmes, projects and activities that bear upon access to medicines: − give particular attention to disadvantaged individuals and communities, such as those living in poverty; − give particular attention to gender-related issues; − give particular attention to the needs of children; − give particular attention to the very poorest in all markets; − be transparent; − encourage and facilitate the participation of all stakeholders, including disadvantaged individuals and communities. (guidelines 6(i)-(vi)) Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 8.
  • 9.
  • 10. The societal return on pharmaceutical investment 0% 80 Heart Cancer Stroke All causes Disease 75 Females -10% -15% -14% 70 Males -20% -19% US life expectancy Years at birth Drop in death rates 1990-2000 among 65 -27% US pop. 45-64 1960 1970 1980 1990 2000 -30% 20 26.%1503 19.7% 0%51982 19 30% 26.2% 15 19.7% 20% 10 10% US pop. > 65 Average length of stay in 5 with disability patient days 0% 0 1982 1999 1960 1970 1980 1990 2000 Sources: OECD Health Data 2004; Health, United States, 2003: Chartbook on Trends in the Health of Americans; Manton KG, Gu X., Proc Natl Acad Sci USA 2001 May 22; 98(11):6354-9. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 11.
  • 12. Measuring misery About 2.5 billion people live on less than USD 2 a day; The richest 20% of the world’s population receive 85% of the global income, the poorest 20% only 1.4% Average life expectancy in the poorest countries of Africa is less than 45 years Every year more than 500 000 women die in pregnancy and childbirth – one every minute 14 million children die every year due to preventable diseases Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 13. The “difficult” Corporate Responsibility challenges Market failures and failing states • Who is in charge if markets fail to help cope with poverty diseases or if those that are supposed to be in charge are not delivering – because they are not capable or willing? • Under which conditions can a business enterprise be expected to do what for whom until when? • How much is enough? What is “appropriate” in a world with 2.5 billion people living in absolute poverty? Who has the legitimacy to determine the “right amounts”? • Under which conditions is it legitimate to conduct clinical trials in developing countries? • etc. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 14. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 15. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 16. Corporate Responsibility Tools for the „Access to Medicine“  Differential Pricing;  Licensing for market failure;  Corporate Philanthropy incl. Donations;  Pro Bono Research;  Screening of Patent Library;  Program Co-operation with Development Institutions  Management Support (Human Resources, Logistics, etc.)  Other innovative and creative private sector skills and methods. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 17. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 18. Novartis is known as a leader in drug access efforts Leprosy (free to WHO1): Over four million patients treated since 2000 Malaria / Coartem: 66 million treatments delivered in 2007 Access programs Tuberculosis (with WHO): worth USD 950 500 000 free treatments provided over five years million reached 66 million patients in 2007 Glivec2 Patient Assistance Program: Free therapy to 27 000 people in 80 countries Novartis Institute for Tropical Diseases: Singapore-based research initiative 1 World Health Organization 2 Gleevec in US Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 19. Why bother with Access to Medicines issues? Because it is the right thing to do: You cannot have a first class economic performance and be perceived not to care about preventable mortality and morbidity. Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only
  • 20. Plausible arguments for a “Business Case” Applied Corporate Responsibility for Access to Medicines is likely to  Save Lives and prevent morbidity by providing innovative solutions;  Be “part of the solution” of one of the most difficult social issues;  Engender employees’ motivation and identification;  Enhance the attraction of the corporation as a partner for cooperation, ethical investment, excellent people, and critical customers). Maputo Conference |Klaus M. Leisinger |September 9th,.2008 | | Business Use Only