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Impact of Dietary Pattern on Human Life
Quality and Life Expectancy: A Mini-Review
Introduction
It is known that a remarkable increase in life expectancy and
ageing population increase day by day [1]. During the lifespan, there
are multiple factors influence the longevity including genotype,
metabolism, physiology, sociodemographic and environmental
factors, nutritional and lifestyle habv its. A healthy lifestyle is
fundamental in disease prevention and expanding longevity [2,3].
Nutrition during the life time has an effect on the health status.
Healthy lifestyle is related with reduced chronic disease risk [4].
The prospective cohort study with Chinese women showed that
healthy lifestyle factors such as lower central adiposity, physical
activity, non-smoking, fruit and vegetable consumption related
with total and cause specific mortality [5]. In addition, a multi-
ethnic cohort study results indicated that chronic disease risk index
was inversely associated with lifespan [6]. Thus, the studies of
lifestyle factors and survival focused on the importance of healthy
lifestyle behaviors such as diet quality, non-smoking, and physical
activity to get long-term health benefits. The 10 years longitudinal
SENECA Study is conducted with 70-75 years old 1091 men and
1109 women in 9 European countries and the results point that
smoking, low diet quality and less physical activity is related with
the survival. Unhealthy lifestyle includes smoking, low diet quality
and less physical activity increased mortality risk three to four
fold. While non-smoking and less physical activity increased the
mortality risk and delayed breakdown of the health status, diet is
not have obvious effect alone. Related with that the lifestyle habit
constituents such as nutrition, physical activity and smoking can
modify to be healthier could improve the quality of life by delay
the morbidity [7-9]. Dietary pattern is the well known important
context of a healthy lifestyle and affects mortality. In this paper it is
aimed to review the relation between human dietary pattern and
life quality-expectancy.
Dietary Pattern
The studies related with nutrition and life expectancy can
generally classified into three types. The first type includes the
nutritionrelatedindicatorsandmortalitydata.Secondtypeincludes
population risk rate to support effects of nutrition on morbidity
and disease cause mortality. While first type established direct,
second type established indirect relation between nutrition and
life expectancy. Third type involves regional nutrition level and life
expectancy analysis [10]. Dietary indexes, certain dietary patterns
and dietary guidelines have been used for analysing dietary pattern
and life expectancy relationship in many studies [11].
Diet Quality
Longer lifespan is associated with obesity, cardiovascular
diseases (CVD), type II diabetes, cancer which are nutrition-related
chronic diseases [12]. A Nurses Health cohort study showed that
greater Alternative Healthy Eating Index-2010 and Alternate
Mediterrannean Diet scores in midlife related with healthy ageing
[13]. Diet quality is one of the main part of life quality, thus related
with longevity. The Diet Quality Index was developed to measure
overall dietary patterns, predict chronic disease risk but also
Mini Review
Research & Investigations in
Sports Medicine
C CRIMSON PUBLISHERS
Wings to the Research
170
Copyright © All rights are reserved by Ceren Gezer.
Volume -2 Issue - 5
Ceren Gezer*
Department of Nutrition and Dietetics, Eastern Mediterranean University, Cyprus
*Corresponding author: Ceren Gezer, Department of Nutrition and Dietetics, Faculty of Health Sciences, Eastern Mediterranean University,
Famagusta, North Cyprus/Mersin 10, Turkey
Submission: February 26, 2018; Published: May 03, 2018
ISSN: 2577-1914
Abstract
During the lifespan, there are multiple factors influence the longevity including genotype, metabolism, physiology, sociodemographic and
environmental factors, nutritional and lifestyle habits. Nutrition during the life time has an effect on the health status. Dietary indexes, certain dietary
patterns and dietary guidelines have been used for analysing dietary pattern and life expectancy relationship in many studies. Dietary pattern has
an important effect on longevity. The cohort study results indicate that diet quality and Medittarenean diet have potential effects on longevity. The
important effects of nutrition on longevity related with quality, quantity, frequency, variety and emotional satisfaction. Therefore, nutritional strategies
that provide clear benefits for ageing linked with both physiological and psychological functions to maintain life quality. The aspiration is not only to
“live longer” but to “live better,” and to maintain optimal qual¬ity of life during the later stages of life.
Keywords: Dietary pattern; Diet quality; Longevity; Life quality; Lifespan
Res Inves Sports Med Copyright © Ceren Gezer
171
How to cite this article: Ceren G. Impact of Dietary Pattern on Human Life Quality and Life Expectancy: A Mini-Review. Res Inves Sports Med 2(5).
RISM.000546.2018. DOI: 10.31031/RISM.2018.02.000546.
Volume - 2 Issue - 5
can used as a predictor of short-term mortality [14,15]. Another
longitudinal study with 3328 old men (60-79 years), Healthy
Diet Indicator (based on WHO dietary guidelines) and the Elderly
Dietary Index (based on a mediterranean dietary pattern) indicated
that high diet quality is associated with all-cause mortality [16]. In
addition, the longitudinal British Diet and Nutrition Survey with
972 participants (aged ≥65 years) measured the diet quality with
three index and while the Healthy Diet Score was not a predictor
of mortality, the Recommended Food Score and the Mediterranean
Diet Score were related with all-cause mortality [17]. Also, the
Breast Cancer Detection Demonstration Project, a prospective
cohort study results showed that low diet quality is related with
increased mortality risk [18]. In addition, American Cancer Society
Cancer Prevention Study II Nutrition Cohort study results indicate
that diet quality was related with all cause and all circulatory
disease mortality rates [15]. According to results of First National
Health and Nutrition Examination Survey (NHANNES)-I low
dietary diversity significantly correlates with high mortality risk of
both men and women [19]. Another prospective study in Sweden
conducted with women, demonstrated that cancer mortality of
women who consume high consumption of red meats, refined
carbohydrates, sugars, foods involve high saturated and trans fat
is higher than women who consume that foods low amount [20].
According to the 16-year follow-up Whitehall II cohort study
results, to be avoide from fried and sweet food, processed and red
meat, refined grains, and high-fat dairy products is associated with
a higher odds of disease-free and highly functional elderly [21].
Also, the prospective study in Europe with 452,717 participants
indicated that increased fiber is associated with lower total
mortality rate, and as a fiber source cereals-vegetables have effects
more than fruits [22].
Mediterranean Diet
The characteristics of Mediterranean diet is a high intake of
vegetables, legumes, fruits, and cereals; a moderate to high intake
of fish; high intake of unsaturated lipids, a low to moderate intake
of dairy products, a low intake of meat; and a modest intake of
wine. Several studies have reported inverse associations with
Meditteranean diet and overall mortality [23]. Mediterranean diet
was inversely associated with total mortality with 22,043 adults in
Greece [24]. The findings of the HALE Project which was conducted
between the years of 1988-2000 with 2339 healthy participants
aged between 70-90 years indicated that a Mediterranean diet and
healthy lifestyle lower all-causes and cause-specific mortality at
least 50% [25]. Moreover, the European Prospective Investigation
into Cancer and Nutrition (EPIC)-elderly prospective cohort study
conducted with 74,607 participant aged <60 years at nine European
countries found out the association between Mediterranean diet
and lowering overall death rate [23]. Besides that, the cohort study
conducted with Dutch women aged 60-69 years found out that a
Healthy Traditional Dutch diet, more beneficial than Mediterranean
diet for longevity [26]. The study with older Swedish participants
showed that Mediterranean dietary patterns including whole
grain cereals, foods rich in polyunsaturated fatty acids, and a
limited amount of alcohol can increase the longevity in the elderly
[27]. Also, it is known that moderate wine consumption, another
characteristic of Meditarrenean Diet reduces CVD risk and extend
lifespan related with its resveratrol content [28]. In addition, the 12
years follow up study which is conducted with young women aged
30-49 years in Sweden showed that Mediterranean dietary pattern
reduces overall and cancer mortality [29]. Furthermore, the cohort
EPIC-Spain with 40,622 participants demostrated that olive oil is
associated with 26% reduction of overall mortality and each 10 g
increase of olive oil consumption decreased overall mortality 7%
rates [30]. Besides that the National Institutes of Health diet and
health study included 214 284 men and 166 012 women showed
that medittarenean dietary pattern reduced overall, cancer and
CVD mortality in United States [31]. The results of meta-analysis of
12 studies indicated that medittarenean diet significantly reduced
overall mortality (9%), mortality from cardiovascular disease (9%)
and cancer mortality (6%) [32].
Vegeterian Diet
The results of reviewed data of the six studies indicated that in
four studies there was a relation between a very low meat intake
and decreased risk of death and the findings from one cohort of
healthy adults showed that long-term (≥2 decades) vegetarian
diet can produce 3.6 years increase in life expectancy [33]. On the
other hand, meat consumption was not associated with mortality
according to results of NHANNES III which was conducted with
17,611 participants between 1986-2010 [34]. Moreover, according
to the position paper of American Dietetic Association a vegetarian
diet is related with a lower risk of death ischemic heart disease and
the evidence based level is grade I-good [35].
Calorie Restriction
This term defined as energy restriction without malnutrition.
Since the first published research on calorie restriction and
extended longevity in rats, many studies conducted with lifespan
in a variety of spices including yeast, flies, worms, fish, mice and
rats. The calorie restriction studies on mice and rat indicated that
delays ageing [36-38]. In addition, studies conducted with Rhesus
monkeys as primates evolutionary closer to humans demonstrated
that 30% calorie restricted diet reduces age-related and all-cause
mortality [39]. The findings of long term epidemiological study
with Okinawans indicated that low calorie intake, little weight gain
with age, life-long low body mass index linked with low risk for age
related disease mortality and extended lifespan [40]. Therefore,
longest-lived people Okinawans live 4 year longer than Americans
since their low calories and nutritionally dense traditional diet
[41,42]. Moreover, longterm human studies data showed that
several metabolic adaptations such as of insulin, insulin like growth
factor-1 and interleukin-6, reduction of triodothyronine level and
body temperature, oxidative damage, natural genetic variants in
nutrient sensing pathways and alterations in autonomic function
reduce the risk of type 2 diabetes, hypertension, cardiovascular
disease and cancer thus extend the life span [43-47]. Hence,
different responses of organisims to dietary restriction need to
172
How to cite this article: Ceren G. Impact of Dietary Pattern on Human Life Quality and Life Expectancy: A Mini-Review. Res Inves Sports Med 2(5).
RISM.000546.2018. DOI: 10.31031/RISM.2018.02.000546.
Res Inves Sports Med Copyright © Ceren Gezer
Volume -2 Issue - 5
design new or improved further studies to understand metabolic,
molecular pathways related with calorie restriction and longevity.
Conclusion
To conclude, while the complicated interactions between caloric
intake, dietary pattern and genotype in relation with longevity are
difficult to study in mammals. The findings concur that healthy
lifestyle behaviours, which includes a healthy nutrition, moderate
physical activity, and non-smoking, increased life expectancy. The
important effects of nutrition on longevity related with quality,
quantity, frequency, variety and emotional satisfaction. Therefore,
nutritional strategies that provide clear benefits for ageing linked
with both physiological and psychological functions to maintain life
quality. The aspiration is not only to “live longer” but to “live better,”
and to maintain optimal qual¬ity of life during the later stages of life.
Thus, healthy nutrition and other lifestyle behaviours are crucial
for this aim. Moreover, a holistic view on ageing and nutrition
could not be only related with diet and lowering morbidity, leads
to mortality but also could be related with healthy ageing without
morbidity risk.
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RISM.000546.2018. DOI: 10.31031/RISM.2018.02.000546.
Volume - 2 Issue - 5
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Impact of Dietary Patterns on Lifespan & Quality

  • 1. Impact of Dietary Pattern on Human Life Quality and Life Expectancy: A Mini-Review Introduction It is known that a remarkable increase in life expectancy and ageing population increase day by day [1]. During the lifespan, there are multiple factors influence the longevity including genotype, metabolism, physiology, sociodemographic and environmental factors, nutritional and lifestyle habv its. A healthy lifestyle is fundamental in disease prevention and expanding longevity [2,3]. Nutrition during the life time has an effect on the health status. Healthy lifestyle is related with reduced chronic disease risk [4]. The prospective cohort study with Chinese women showed that healthy lifestyle factors such as lower central adiposity, physical activity, non-smoking, fruit and vegetable consumption related with total and cause specific mortality [5]. In addition, a multi- ethnic cohort study results indicated that chronic disease risk index was inversely associated with lifespan [6]. Thus, the studies of lifestyle factors and survival focused on the importance of healthy lifestyle behaviors such as diet quality, non-smoking, and physical activity to get long-term health benefits. The 10 years longitudinal SENECA Study is conducted with 70-75 years old 1091 men and 1109 women in 9 European countries and the results point that smoking, low diet quality and less physical activity is related with the survival. Unhealthy lifestyle includes smoking, low diet quality and less physical activity increased mortality risk three to four fold. While non-smoking and less physical activity increased the mortality risk and delayed breakdown of the health status, diet is not have obvious effect alone. Related with that the lifestyle habit constituents such as nutrition, physical activity and smoking can modify to be healthier could improve the quality of life by delay the morbidity [7-9]. Dietary pattern is the well known important context of a healthy lifestyle and affects mortality. In this paper it is aimed to review the relation between human dietary pattern and life quality-expectancy. Dietary Pattern The studies related with nutrition and life expectancy can generally classified into three types. The first type includes the nutritionrelatedindicatorsandmortalitydata.Secondtypeincludes population risk rate to support effects of nutrition on morbidity and disease cause mortality. While first type established direct, second type established indirect relation between nutrition and life expectancy. Third type involves regional nutrition level and life expectancy analysis [10]. Dietary indexes, certain dietary patterns and dietary guidelines have been used for analysing dietary pattern and life expectancy relationship in many studies [11]. Diet Quality Longer lifespan is associated with obesity, cardiovascular diseases (CVD), type II diabetes, cancer which are nutrition-related chronic diseases [12]. A Nurses Health cohort study showed that greater Alternative Healthy Eating Index-2010 and Alternate Mediterrannean Diet scores in midlife related with healthy ageing [13]. Diet quality is one of the main part of life quality, thus related with longevity. The Diet Quality Index was developed to measure overall dietary patterns, predict chronic disease risk but also Mini Review Research & Investigations in Sports Medicine C CRIMSON PUBLISHERS Wings to the Research 170 Copyright © All rights are reserved by Ceren Gezer. Volume -2 Issue - 5 Ceren Gezer* Department of Nutrition and Dietetics, Eastern Mediterranean University, Cyprus *Corresponding author: Ceren Gezer, Department of Nutrition and Dietetics, Faculty of Health Sciences, Eastern Mediterranean University, Famagusta, North Cyprus/Mersin 10, Turkey Submission: February 26, 2018; Published: May 03, 2018 ISSN: 2577-1914 Abstract During the lifespan, there are multiple factors influence the longevity including genotype, metabolism, physiology, sociodemographic and environmental factors, nutritional and lifestyle habits. Nutrition during the life time has an effect on the health status. Dietary indexes, certain dietary patterns and dietary guidelines have been used for analysing dietary pattern and life expectancy relationship in many studies. Dietary pattern has an important effect on longevity. The cohort study results indicate that diet quality and Medittarenean diet have potential effects on longevity. The important effects of nutrition on longevity related with quality, quantity, frequency, variety and emotional satisfaction. Therefore, nutritional strategies that provide clear benefits for ageing linked with both physiological and psychological functions to maintain life quality. The aspiration is not only to “live longer” but to “live better,” and to maintain optimal qual¬ity of life during the later stages of life. Keywords: Dietary pattern; Diet quality; Longevity; Life quality; Lifespan
  • 2. Res Inves Sports Med Copyright © Ceren Gezer 171 How to cite this article: Ceren G. Impact of Dietary Pattern on Human Life Quality and Life Expectancy: A Mini-Review. Res Inves Sports Med 2(5). RISM.000546.2018. DOI: 10.31031/RISM.2018.02.000546. Volume - 2 Issue - 5 can used as a predictor of short-term mortality [14,15]. Another longitudinal study with 3328 old men (60-79 years), Healthy Diet Indicator (based on WHO dietary guidelines) and the Elderly Dietary Index (based on a mediterranean dietary pattern) indicated that high diet quality is associated with all-cause mortality [16]. In addition, the longitudinal British Diet and Nutrition Survey with 972 participants (aged ≥65 years) measured the diet quality with three index and while the Healthy Diet Score was not a predictor of mortality, the Recommended Food Score and the Mediterranean Diet Score were related with all-cause mortality [17]. Also, the Breast Cancer Detection Demonstration Project, a prospective cohort study results showed that low diet quality is related with increased mortality risk [18]. In addition, American Cancer Society Cancer Prevention Study II Nutrition Cohort study results indicate that diet quality was related with all cause and all circulatory disease mortality rates [15]. According to results of First National Health and Nutrition Examination Survey (NHANNES)-I low dietary diversity significantly correlates with high mortality risk of both men and women [19]. Another prospective study in Sweden conducted with women, demonstrated that cancer mortality of women who consume high consumption of red meats, refined carbohydrates, sugars, foods involve high saturated and trans fat is higher than women who consume that foods low amount [20]. According to the 16-year follow-up Whitehall II cohort study results, to be avoide from fried and sweet food, processed and red meat, refined grains, and high-fat dairy products is associated with a higher odds of disease-free and highly functional elderly [21]. Also, the prospective study in Europe with 452,717 participants indicated that increased fiber is associated with lower total mortality rate, and as a fiber source cereals-vegetables have effects more than fruits [22]. Mediterranean Diet The characteristics of Mediterranean diet is a high intake of vegetables, legumes, fruits, and cereals; a moderate to high intake of fish; high intake of unsaturated lipids, a low to moderate intake of dairy products, a low intake of meat; and a modest intake of wine. Several studies have reported inverse associations with Meditteranean diet and overall mortality [23]. Mediterranean diet was inversely associated with total mortality with 22,043 adults in Greece [24]. The findings of the HALE Project which was conducted between the years of 1988-2000 with 2339 healthy participants aged between 70-90 years indicated that a Mediterranean diet and healthy lifestyle lower all-causes and cause-specific mortality at least 50% [25]. Moreover, the European Prospective Investigation into Cancer and Nutrition (EPIC)-elderly prospective cohort study conducted with 74,607 participant aged <60 years at nine European countries found out the association between Mediterranean diet and lowering overall death rate [23]. Besides that, the cohort study conducted with Dutch women aged 60-69 years found out that a Healthy Traditional Dutch diet, more beneficial than Mediterranean diet for longevity [26]. The study with older Swedish participants showed that Mediterranean dietary patterns including whole grain cereals, foods rich in polyunsaturated fatty acids, and a limited amount of alcohol can increase the longevity in the elderly [27]. Also, it is known that moderate wine consumption, another characteristic of Meditarrenean Diet reduces CVD risk and extend lifespan related with its resveratrol content [28]. In addition, the 12 years follow up study which is conducted with young women aged 30-49 years in Sweden showed that Mediterranean dietary pattern reduces overall and cancer mortality [29]. Furthermore, the cohort EPIC-Spain with 40,622 participants demostrated that olive oil is associated with 26% reduction of overall mortality and each 10 g increase of olive oil consumption decreased overall mortality 7% rates [30]. Besides that the National Institutes of Health diet and health study included 214 284 men and 166 012 women showed that medittarenean dietary pattern reduced overall, cancer and CVD mortality in United States [31]. The results of meta-analysis of 12 studies indicated that medittarenean diet significantly reduced overall mortality (9%), mortality from cardiovascular disease (9%) and cancer mortality (6%) [32]. Vegeterian Diet The results of reviewed data of the six studies indicated that in four studies there was a relation between a very low meat intake and decreased risk of death and the findings from one cohort of healthy adults showed that long-term (≥2 decades) vegetarian diet can produce 3.6 years increase in life expectancy [33]. On the other hand, meat consumption was not associated with mortality according to results of NHANNES III which was conducted with 17,611 participants between 1986-2010 [34]. Moreover, according to the position paper of American Dietetic Association a vegetarian diet is related with a lower risk of death ischemic heart disease and the evidence based level is grade I-good [35]. Calorie Restriction This term defined as energy restriction without malnutrition. Since the first published research on calorie restriction and extended longevity in rats, many studies conducted with lifespan in a variety of spices including yeast, flies, worms, fish, mice and rats. The calorie restriction studies on mice and rat indicated that delays ageing [36-38]. In addition, studies conducted with Rhesus monkeys as primates evolutionary closer to humans demonstrated that 30% calorie restricted diet reduces age-related and all-cause mortality [39]. The findings of long term epidemiological study with Okinawans indicated that low calorie intake, little weight gain with age, life-long low body mass index linked with low risk for age related disease mortality and extended lifespan [40]. Therefore, longest-lived people Okinawans live 4 year longer than Americans since their low calories and nutritionally dense traditional diet [41,42]. Moreover, longterm human studies data showed that several metabolic adaptations such as of insulin, insulin like growth factor-1 and interleukin-6, reduction of triodothyronine level and body temperature, oxidative damage, natural genetic variants in nutrient sensing pathways and alterations in autonomic function reduce the risk of type 2 diabetes, hypertension, cardiovascular disease and cancer thus extend the life span [43-47]. Hence, different responses of organisims to dietary restriction need to
  • 3. 172 How to cite this article: Ceren G. Impact of Dietary Pattern on Human Life Quality and Life Expectancy: A Mini-Review. Res Inves Sports Med 2(5). RISM.000546.2018. DOI: 10.31031/RISM.2018.02.000546. Res Inves Sports Med Copyright © Ceren Gezer Volume -2 Issue - 5 design new or improved further studies to understand metabolic, molecular pathways related with calorie restriction and longevity. Conclusion To conclude, while the complicated interactions between caloric intake, dietary pattern and genotype in relation with longevity are difficult to study in mammals. The findings concur that healthy lifestyle behaviours, which includes a healthy nutrition, moderate physical activity, and non-smoking, increased life expectancy. The important effects of nutrition on longevity related with quality, quantity, frequency, variety and emotional satisfaction. Therefore, nutritional strategies that provide clear benefits for ageing linked with both physiological and psychological functions to maintain life quality. The aspiration is not only to “live longer” but to “live better,” and to maintain optimal qual¬ity of life during the later stages of life. Thus, healthy nutrition and other lifestyle behaviours are crucial for this aim. Moreover, a holistic view on ageing and nutrition could not be only related with diet and lowering morbidity, leads to mortality but also could be related with healthy ageing without morbidity risk. References 1. World Health Organisation (2015) World report on ageing and health. World Health Organisation Press, Switzerland. 2. Slawson DL, Fitzgerald N, Morgan KT (2013) Position of the academy of nutrition and dietetics: The role of nutrition in health promotion and chronic disease prevention. Journal of Academy of Nutrition and Dietet- ics 113(7): 972-979. 3. Chrysohoou C, Stefanadis C (2013) Longevity and diet. 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