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.Organ :- Intestine-
Disease :- Para T.B-
 .Stain :- H & E-
Lesion :- The intestinal mucosa is filled with-
macrophages , giant cells and lymphocytes
((granulomatous reaction
Paratuberculosis
paratuberculosis
Organ: intestine
Stain: Ziehl Neelsen
lesion: the acid-fast bacilli is seen in the
  intestinal mucosa
Paratuberculosis
organ :- Endometrium-
-Stain :- H & E
-Disease :- Brucellosis
-Lesion :- severe endometritis represented by
preglandular round cell infiltration necrotic
endometeritis ch. By necrotic epi. + Adhesion
 .with few infl. Cell infiltration
Brucellosis
organ :- Endometrium-
-Stain :- H & E
-Disease :- Brucellosis
-Lesion :- severe endometritis represented by
preglandular round cell infiltration +Edema
Brucellosis
.Organ :- liver-
 .Stain :- H & E-
 .Disease :- Brucellosis-
Lesion :- presence of pyogranuloma-
characterized by presence of Caseous necrosis
surrounded by epithelioid cells , giant cells
and neutrophils then enclosed by fibrous C.T
Brucellosis
.Organ :- liver-
 .Stain :- H & E-
 .Disease :- Brucellosis-
Lesion :- presence of pyogranuloma-
characterized by presence of Caseous necrosis
surrounded by epithelioid cells , giant cells
and neutrophils then enclosed by fibrous C.T
Brucellosis
.Organ :- liver-
 .Stain :- H & E-
 .Disease :- Brucellosis-
Lesion :- presence of pyogranuloma-
characterized by presence of Caseous necrosis
surrounded by epithelioid cells , giant cells
and neutrophils then enclosed by fibrous C.T
Brucellosis
.Organ :- Lung-
Stain :- H & E-
Disease :- T.B-
Micro :- Granulomatous reaction + calcification-
 .in center
Tuberculosis
.Organ :- Lymph node-
.Stain :- H & E-
Disease :- T.B-
Micro :- Granulomatous reaction + caseation &-
.calcification
Tuberculosis
.Organ :- Kidney-
Stain :- H & E-
Disease :- T.B-
 .Micro :- Granulomatous reaction + Giant cells-
Tuberculosis
Tuberculosis
.Organ :- Lung-
 .Stain :- H & E-
 .Disease :- Pneumonic pasteurellosis-
Lesion :- Fibrous bronchopneumonia-
characterized by filling of alveoli with
serofibrinous exudate infiltrated with
neutrophils and macrophages , congestion of
 interalveolar capillaries and hemorrhage
Pasteurellosis
.Organ :- Lung-
 .Stain :- H & E-
 .Disease :- Pneumonic pasteurellosis-
Lesion :- Fibrous bronchopneumonia-
characterized by filling of alveoli with
serofibrinous exudate infiltrated with
neutrophils and macrophages , congestion of
 interalveolar capillaries and hemorrhage
Pasteurellosis
Pneumonic pasteurellosis
.Organ :- Lung-
.Stain :- Silver stain-
.Disease :- Pneumonic pasteurellosis-
Lesion :- Blackish stained P.hemorrage freely-
inside alveolar lumen & trapped intra-alveolar
.macrophage
Pasteurellosis
.Organ :- Lung-
 .Stain :- IHC-
 .Disease :- pneumonic pasteurellosis-
Lesion :- Positive brown immunolabelling-
against P.multocida mainly inside cytoplasm
 .of macrophages infiltrating lumen of alveoli
Pasteurellosis
Pasteurellosis
Organ :- Spinal cord-
Stain :- H & E-
 ( Disease :- Actinomycosis ( A.pyogenes-
Lesion :- Consists of centrally located bacterial-
colonies surrounded by number of neutrophil,
lymphocyte & epithelioid cells all surrounded
by Fibrous C.T
Actinomyces pyogenes
     A. pyogenes
Actinomyces pyogenes
Organ :- Spinal cord-
Stain :- H & E-
 ( Disease :- Actinomycosis ( A.pyogenes-
Lesion :- Consists of centrally located bacterial-
colonies surrounded by number of neutrophil,
lymphocyte & epithelioid cells all surrounded
by Fibrous C.T
Actinomyces pyogenes
Actinomyces pyogenes
Actinomyces pyogenes
Actinomyces pyogenes
Actinomyces pyogenes
Organ :- Intestine-
 (Stain :- IHC ( ImmunoHistoChemestry-
 Lesion :- Lowsenia enteritis-
Micro :- Brown stained lowsenia enteritis in-
lamina propria & in between intestine villi
Lawsonia intracellularis
Organ :- Intestine-
 (Stain :- IHC ( ImmunoHistoChemestry-
 Lesion :- Lowsenia enteritis-
Micro :- Brown stained lowsenia enteritis in-
lamina propria & in between intestine villi
Lawsonia intracellularis
.Organ :- Lung-
.Disease :- Avian influenza-
Micro :- Congestion, perivascular edema &-
.fibrosis
Avian influenza -Lung
Avian influenza - Spleen
Avian influenza
Organ: spleen
 Stain: H &E
 Disease: Avian influenza
Lesion: hemorrhage , congestion & hemolysis of
 red pulp
Avian influenza ( High power of
            ( spleen
Avian influenza
Organ: lung
 Stain: H &E
 Disease: Avian influenza
Lesion: congestion, haemorrhage and
  hemosiderosis
Avian influenza
Organ :- Heart-
Stain :- H & E-
Disease :- Leukosis sarcoma-
Micro :- Focal invasion & replacement of-
myocardium with pleomorphic leukocytes
Avian leukosis
.Organ :- Intestine-
 .Stain :- H&E-
 .Disease :- Intestinal coccidiosis-
Micro :- Various developmental stages of-
coccidia were seen in the epithelial lining of
intestinal crypts (arrow) or free in lamina
( .propria besides extravasated RBCs (arrow
Intestinal coccidiosis
Intestinal coccidiosis
Intestinal coccidiosis
.Organ :- Intestine-
 .Stain :- H & E-
 .Disease :- Ascariasis-
Lesion :- Presence of adult worm in the lumen-
 .of intestine with desquamation of epithelium
Fowl Ascariasis
dermatophytosis
•   Organ: skin
•   Lesion:- dermatophytosis
•   Stain: H&E
•   Micro: severe inflammatory in skin beside
    loss of hair shaft and ectothrix
Dermatophtosis
Dermatophtosis – Hair follicle
.Organ :- Lung-
.Stain :- PAS-
.Disease :- Dermatophytosis-
Micro :- PAS + hyphae are seen in skin-
( .( Brownish color
.Organ :- Lung-
 .Stain :- H & E-
 .Disease :- Aspergillosis-
Micro :- severe pneumonia appear as dense-
rounded fosci eosinophilic center beside
 .granulomatous reaction
Aspergillosis
.Organ :- Intestine-
Disease :- Para T.B-
 .Stain :- H & E-
Lesion :- The intestinal mucosa is filled with-
macrophages , giant cells and lymphocytes
((granulomatous reaction
paratuberculosis - 9
Organ :- spleen-
Stain :- H & E-
Disease :- Brucellosis-
Micro :- pyogranulomatous spleen represented-
by aggregation of mononuclear cells,
epithelioid cells & neutrophil
.Organ :- liver-
 .Stain :- H & E-
 .Disease :- Brucellosis-
Lesion :- presence of pyogranuloma-
characterized by presence of Caseous necrosis
surrounded by epithelioid cells , giant cells
and neutrophils then enclosed by fibrous C.T
Brucellosis-17
Pneumonic pasteurellosis
.Organ :- Lung-
.Stain :- Silver stain-
.Disease :- Pneumonic pasteurellosis-
Lesion :- Blackish stained P.hemorrage freely-
inside alveolar lumen & trapped intra-alveolar
.macrophage
Pneumonic pasteurellosis silver stain
.Organ :- Lung-
 .Stain :- H & E-
 .Disease :- Pneumonic pasteurellosis-
Lesion :- Fibrous bronchopneumonia-
characterized by filling of alveoli with
serofibrinous exudate infiltrated with
neutrophils and macrophages , congestion of
 interalveolar capillaries and hemorrhage
Pneumonic pasteurellosis H & E-6
.Organ :- Lung-
 .Stain :- IHC-
 .Disease :- pneumonic pasteurellosis-
Lesion :- Positive brown immunolabelling-
against P.multocida mainly inside cytoplasm
 .of macrophages infiltrating lumen of alveoli
Pneumonic pasteurellosis IHC- 7
Pneumonic pasteurellosis IHC- 7
Organ :- Lung-
Stain :- H & E-
Disease :- Avian influenza-
Micro :- Congestion & infiltration with-
mononuclear cell in the interstitial tissue
Lung - Avian influenza
Organ :- Heart-
Stain :- H & E-
Disease :- Leukosis sarcoma-
Micro :- Focal invasion & replacement of-
myocardium with pleomorphic leukocytes
Heart - Leukosis sarcoma
Organ :- Spleen-
Stain :- H & E-
Disease :- Avian influenza-
Micro :- Periarteriolar edema & necrosis of-
 lymphoid tissue
Spleen - Avian influenza
Organ :- Spinal cord-
Stain :- H & E-
 ( Disease :- Actinomycosis ( A.pyogenes-
Lesion :- Consists of centrally located bacterial-
colonies surrounded by number of neutrophil,
lymphocyte & epithelioid cells all surrounded
by Fibrous C.T
(Actinomycosis ( A.pyogenes
(Actinomycosis ( A.pyogenes
Organ :- Intestine-
 (Stain :- IHC ( ImmunoHistoChemestry-
 Lesion :- Lowsenia enteritis-
Micro :- Brown stained lowsenia enteritis in-
lamina propria & in between intestine villi
Lowsenia enteritis
.Organ :- Intestine-
 .Stain :- H & E-
 .Disease :- Ascariasis-
Lesion :- Presence of adult worm in the lumen-
 .of intestine with desquamation of epithelium
.Organ :- Intestine-
 .Stain :- H&E-
 .Disease :- Intestinal coccidiosis-
Micro :- Various developmental stages of-
coccidia were seen in the epithelial lining of
intestinal crypts (arrow) or free in lamina
( .propria besides extravasated RBCs (arrow
.Organ :- Skin-
  .Stain :- H&E-
  .Disease :- Fowl pox-
Micro :- The skin showed hyperplasia of prickle-
cell layer which contain ICIB moreover the
prickle cell layer shows hydropic degeneration
.
.Organ :- Lung-
.Stain :- PAS-
.Disease :- Dermatophytosis-
Micro :- PAS + hyphae are seen in skin-
( .( Brownish color
.Organ :- Skin-
 .Stain :- H & E-
 .Disease :- Dermatophytosis-
Micro :- Severe inflammatory reaction-
(dermatitis) in the skin besides loss of hair
shaft, the presence of perifollicular ectothrix,
 . arthrospores & hyperkeratosis
.Organ :- Lung-
 .Stain :- H & E-
 .Disease :- Aspergillosis-
Micro :- severe pneumonia appear as dense-
rounded fosci eosinophilic center beside
 .granulomatous reaction
Practical pathology revision 4th year 1st term 2013 miro
Practical pathology revision 4th year 1st term 2013 miro
Practical pathology revision 4th year 1st term 2013 miro

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Practical pathology revision 4th year 1st term 2013 miro

  • 2. .Organ :- Intestine- Disease :- Para T.B- .Stain :- H & E- Lesion :- The intestinal mucosa is filled with- macrophages , giant cells and lymphocytes ((granulomatous reaction
  • 4. paratuberculosis Organ: intestine Stain: Ziehl Neelsen lesion: the acid-fast bacilli is seen in the intestinal mucosa
  • 6. organ :- Endometrium- -Stain :- H & E -Disease :- Brucellosis -Lesion :- severe endometritis represented by preglandular round cell infiltration necrotic endometeritis ch. By necrotic epi. + Adhesion .with few infl. Cell infiltration
  • 8. organ :- Endometrium- -Stain :- H & E -Disease :- Brucellosis -Lesion :- severe endometritis represented by preglandular round cell infiltration +Edema
  • 10. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis- Lesion :- presence of pyogranuloma- characterized by presence of Caseous necrosis surrounded by epithelioid cells , giant cells and neutrophils then enclosed by fibrous C.T
  • 12. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis- Lesion :- presence of pyogranuloma- characterized by presence of Caseous necrosis surrounded by epithelioid cells , giant cells and neutrophils then enclosed by fibrous C.T
  • 14. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis- Lesion :- presence of pyogranuloma- characterized by presence of Caseous necrosis surrounded by epithelioid cells , giant cells and neutrophils then enclosed by fibrous C.T
  • 16. .Organ :- Lung- Stain :- H & E- Disease :- T.B- Micro :- Granulomatous reaction + calcification- .in center
  • 18. .Organ :- Lymph node- .Stain :- H & E- Disease :- T.B- Micro :- Granulomatous reaction + caseation &- .calcification
  • 20. .Organ :- Kidney- Stain :- H & E- Disease :- T.B- .Micro :- Granulomatous reaction + Giant cells-
  • 23. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis- Lesion :- Fibrous bronchopneumonia- characterized by filling of alveoli with serofibrinous exudate infiltrated with neutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 25. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis- Lesion :- Fibrous bronchopneumonia- characterized by filling of alveoli with serofibrinous exudate infiltrated with neutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 27. Pneumonic pasteurellosis .Organ :- Lung- .Stain :- Silver stain- .Disease :- Pneumonic pasteurellosis- Lesion :- Blackish stained P.hemorrage freely- inside alveolar lumen & trapped intra-alveolar .macrophage
  • 29. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis- Lesion :- Positive brown immunolabelling- against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  • 32. Organ :- Spinal cord- Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes- Lesion :- Consists of centrally located bacterial- colonies surrounded by number of neutrophil, lymphocyte & epithelioid cells all surrounded by Fibrous C.T
  • 33. Actinomyces pyogenes A. pyogenes
  • 34.
  • 36. Organ :- Spinal cord- Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes- Lesion :- Consists of centrally located bacterial- colonies surrounded by number of neutrophil, lymphocyte & epithelioid cells all surrounded by Fibrous C.T
  • 42. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis- Micro :- Brown stained lowsenia enteritis in- lamina propria & in between intestine villi
  • 44. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis- Micro :- Brown stained lowsenia enteritis in- lamina propria & in between intestine villi
  • 46. .Organ :- Lung- .Disease :- Avian influenza- Micro :- Congestion, perivascular edema &- .fibrosis
  • 49. Avian influenza Organ: spleen Stain: H &E Disease: Avian influenza Lesion: hemorrhage , congestion & hemolysis of red pulp
  • 50. Avian influenza ( High power of ( spleen
  • 51. Avian influenza Organ: lung Stain: H &E Disease: Avian influenza Lesion: congestion, haemorrhage and hemosiderosis
  • 53. Organ :- Heart- Stain :- H & E- Disease :- Leukosis sarcoma- Micro :- Focal invasion & replacement of- myocardium with pleomorphic leukocytes
  • 55. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis- Micro :- Various developmental stages of- coccidia were seen in the epithelial lining of intestinal crypts (arrow) or free in lamina ( .propria besides extravasated RBCs (arrow
  • 59. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis- Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  • 61. dermatophytosis • Organ: skin • Lesion:- dermatophytosis • Stain: H&E • Micro: severe inflammatory in skin beside loss of hair shaft and ectothrix
  • 64. .Organ :- Lung- .Stain :- PAS- .Disease :- Dermatophytosis- Micro :- PAS + hyphae are seen in skin- ( .( Brownish color
  • 65.
  • 66. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis- Micro :- severe pneumonia appear as dense- rounded fosci eosinophilic center beside .granulomatous reaction
  • 68.
  • 69. .Organ :- Intestine- Disease :- Para T.B- .Stain :- H & E- Lesion :- The intestinal mucosa is filled with- macrophages , giant cells and lymphocytes ((granulomatous reaction
  • 71. Organ :- spleen- Stain :- H & E- Disease :- Brucellosis- Micro :- pyogranulomatous spleen represented- by aggregation of mononuclear cells, epithelioid cells & neutrophil
  • 72.
  • 73. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis- Lesion :- presence of pyogranuloma- characterized by presence of Caseous necrosis surrounded by epithelioid cells , giant cells and neutrophils then enclosed by fibrous C.T
  • 75. Pneumonic pasteurellosis .Organ :- Lung- .Stain :- Silver stain- .Disease :- Pneumonic pasteurellosis- Lesion :- Blackish stained P.hemorrage freely- inside alveolar lumen & trapped intra-alveolar .macrophage
  • 77. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis- Lesion :- Fibrous bronchopneumonia- characterized by filling of alveoli with serofibrinous exudate infiltrated with neutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 79. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis- Lesion :- Positive brown immunolabelling- against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  • 82. Organ :- Lung- Stain :- H & E- Disease :- Avian influenza- Micro :- Congestion & infiltration with- mononuclear cell in the interstitial tissue
  • 83. Lung - Avian influenza
  • 84. Organ :- Heart- Stain :- H & E- Disease :- Leukosis sarcoma- Micro :- Focal invasion & replacement of- myocardium with pleomorphic leukocytes
  • 85. Heart - Leukosis sarcoma
  • 86. Organ :- Spleen- Stain :- H & E- Disease :- Avian influenza- Micro :- Periarteriolar edema & necrosis of- lymphoid tissue
  • 87. Spleen - Avian influenza
  • 88. Organ :- Spinal cord- Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes- Lesion :- Consists of centrally located bacterial- colonies surrounded by number of neutrophil, lymphocyte & epithelioid cells all surrounded by Fibrous C.T
  • 91. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis- Micro :- Brown stained lowsenia enteritis in- lamina propria & in between intestine villi
  • 93. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis- Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  • 94.
  • 95. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis- Micro :- Various developmental stages of- coccidia were seen in the epithelial lining of intestinal crypts (arrow) or free in lamina ( .propria besides extravasated RBCs (arrow
  • 96.
  • 97. .Organ :- Skin- .Stain :- H&E- .Disease :- Fowl pox- Micro :- The skin showed hyperplasia of prickle- cell layer which contain ICIB moreover the prickle cell layer shows hydropic degeneration .
  • 98.
  • 99. .Organ :- Lung- .Stain :- PAS- .Disease :- Dermatophytosis- Micro :- PAS + hyphae are seen in skin- ( .( Brownish color
  • 100.
  • 101.
  • 102. .Organ :- Skin- .Stain :- H & E- .Disease :- Dermatophytosis- Micro :- Severe inflammatory reaction- (dermatitis) in the skin besides loss of hair shaft, the presence of perifollicular ectothrix, . arthrospores & hyperkeratosis
  • 103.
  • 104.
  • 105. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis- Micro :- severe pneumonia appear as dense- rounded fosci eosinophilic center beside .granulomatous reaction