this ppt is very simple and has immence importance in physical pharmacy. it has been prepared based on the syllabus of WBUT & consists of informations of elimentary label...
Forensic Biology & Its biological significance.pdf
4th (30.10.2014) on eutectic mixture by Diptarco Singha
1.
2.
3. Melts below
the melting
point of
individual
component…
The melting
point is
always
fixed…
During
formation, the
components
are miscible
in liquid state
but
immiscible in
solid state…
4. Below the eutectic
temperature the mixture of
the two substances will exist
as a solid.
While above it the mixture
will convert into a liquid.
(e- Eutectic point)
Point ‘e’ is the lowest melting
point.
5. It is necessary to adjust the ratio of the
components in the mixture.
It is also necessary to closely control
the components for impurities.
6. The components must be miscible in a liquid state & mostly
immiscible in solid state…
The molecules which are in accordance to modified VantHoff’s
equation can form eutectic mixtures…
The components should have chemical groups that can interact
to form physical bonds such has intermolecular hydrogen
bonding etc…
7. Eutectic Mixtures are commonly used in drug designing and delivery
processes for various routes of administration…
Other uses are:-
For the identification of the compounds having similar
melting points.
Local anesthetics in case of children (used topically).