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Title:
Interventions for replacing missing teeth:dental implant, Bacteria, antibiotics and
infections around biomaterials,biofilm-A review.
Author :-
Name: Dr. Aklaqur Rahman Chayon BDS.
Dhaka Dental College.University of Dhaka, Mastership in dental Implantology (Mumbai)
Senior Oral anatomy Lecturer (Department of oral anatomy and histology )DIDMC
Co-author:- Dr Nurjahan Afsary nira BDS(University of Dhaka)
Consultant Dental Surgeon AR Dental maxillofacial care research and training Center,N oral health and
dental care,Banasree Dhaka.
Abstract:
Dental Implants have been shown to an excellent interventions for replacing missing
teeth.Dental implant is a a biomaterials like natural teeth can be affected by
microorganisms like bacteria which even,causes,peri-implantitis, peri-implant mucositis
finally leads to implant failure.Dental implant are impervious to infections.In order to
prevent infections antibiotics are shown to benefit in controlling infections,this review also
seeks establish antibiotics are most effective during interventions of dental implant.There
are many reasons for dental implant failure due to the develop of bacteremia is concern for
dentists. This is due to the possibility of unfavorable result such as implant loss or lead to
failure.
Keywords:
Biomaterials,Bacterial,Biofilm,antibiotic prophylaxis, clinical evidence, dental
implants, implant placement, systematic review.
Introduction:-
Missing teeth can be usually replaced with dental implants in which a
cap/crown,bridge or denture can be attached.During procedure Bacteria
Can lead to infection and sometimes it may cause implant failure.Biomaterials
(like -dental implant ) can be infected and hard to treat.Although implants are
impervious to disease or infection.Supporting Gingivae and bone aren”t prone to
,Plaque,a Biofilm of a food and Bacteria that cultivate on tooth surface ,can causes
infection : gingival diseases that weakens the supporting tissues of implant and
implant itself.
MATERIALS AND METHODS:- Review and meta-analysis, Literature data and
analysis.
DATA SOURCES:
Literature Review ,Electronic databases,Pubmed, Cochrane, Science Direct, and
EMBASE via OVID were searched up to September 2019. Only randomized
controlled clinical trials (RCT) using antibiotics were included. Outcome
measures were set on dental implant failures or postoperative infection incidence
after dental implant surgery.
Result :-
Literature search and Quantitative studies :-
In Data collections Fig- Showing the search results , From 1200 search results, 200
were excluded as they did not relate to human Studies , After that,643 citations were
excluded because they were not clinical trials. 232 citations were discarded and
excluded due to replica. Afterwards 125,studies which were 100 citations were
excluded,mostly due to immue compromised patient ,dental conditions ,or no
implant or no antibiotics .Finally 25 full articles for reviewing quantitative studies
and results.
CONCLUSIONS:
Consequently,Scientific evidence suggests that, in general,
antibiotics are beneficial for reducing failure of dental implants
placed in ordinary conditions. It is still unknown whether
postoperative antibiotics are beneficial, and which antibiotic is
the most effective.
References
1. Adell R, Lekholm U, Rockler B, Brånemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous
jaw. Int J Oral Surg 1981;10:387-416.
2. Tonetti MS, Schmid J. Pathogenesis of implant failures. Periodontol 2000 1994;4:127-38. Back to cited text no. 15.
Quirynen M, Listgarten MA. Distribution of bacterial morphotypes around natural teeth and titanium implants ad modum
Branemark. Clin Oral Implant Res 1990;1:8-12.
3. Apse P, Ellen RP, Overall CM, Zarb GA. Microbiota and crevicular fluid collagenase activity in the osseointegrated dental
implant sulcus: A comparison of sites in edentulous and partially edentulous patients. J Periodont Res 1989;24:96-105. Back to cited text no.
168. Albrektsson T, Isidor F. Consensus report. In: Lang NP, Karring T, editors. Proceedings of the 1 st European workshop on
periodontology; 1994. p. 365-9.
4. Zitzmann NU, Berglundh T. Definition and prevalences of peri-implant diseases. J Clin Periodontol 2008;35:286-91.
5. Fransson C, Lekholm U, Jemt T, Berglundh T. Prevalence of subjects with progressive bone loss at implants. Clin Oral Implant
Res 2005;16:440-6.
6. Fransson C, Wennstrom J, Berglundh T. Clinical characteristics at implants with a history of progressive bone loss. Clin Oral
Implant Res 2008;19:142-7.
7. Karoussis IK, Salvi GE, Heitz-Mayfield L, Bragger J, Hammerle CH, Lang NP. Long-term implant prognosis in patients with and
without a history of chronic periodontitis: A 10 year prospective cohort study of the ITI dental implant system. Clin Oral Implant Res
2003;14:329-39.
8. Roos-Jansaker AM, Lindahl C, Renvert H, Renvert S. Nine to Fourteen year follow-up of implant treatment. Part II: Presence of
peri-implant lesions. J Clin Periodontol 2006;33:290-5.
9. Bragger U, Karaoussis I, Persson R, Pjetursson B, Salvi G, Lang N. Technical and biological complications/failures with single
crowns and fixed partial dentures on implants. A 10 year prospective cohort study. Clin Oral Implant Res 2005;16:326-34.
10. Mombelli A, Van Oosten MA, Schruch E Jr, Land NP. The microbiota associated with successful or failing osseointegrated
titanium implants. Oral Microbiol Immunol 1987;2:145-51.10. Hojo K, Nagaoka S, Oshima T. Bacterial interactions in dental biofilm
development. J Dent Res. 2009;88:982–90.
11. Bassler BL, Wright M, Silverman MR. Multiple signaling systems controlling expressions of luminescence in Vibrio harveyi: Sequence
and function of genes encoding a secondary sensory pathway. Mol Microbiology. 1994;13:273–86.
12. Rams TE, Link CC. Microbiology of failing dental implants in humans. Electron microscopic observation. J Oral Implantol. 1983;11:93–
100.
13. Haffajee AD, Cugini MA, Tanner A, Pollack RP, Smith C Kent RL Jr, Socransky SS. Subgingival microbiota in healthy, well-
maintained elder and periodontitis subjects. J Clin Periodontol 1998;25:346-53.
14. Datta R, Grewal Y, Batth JS, Singh A. Current trend of antimi-crobial prescription for oral implant surgery among dentists in India. J
Maxillofac Oral Surg 2014;13:503 -507.
15. Khalil D, Hultin M, Andersson Fred L, Parkbring Olsson N, Lund B. Antibiotic prescription patterns among Swedish dentists working
with dental implant surgery: adherence to recommen-dations. Clin Oral Implant Res 2015;26:1064 -1069.
16. Deeb GR, Soung GY, Best AM, Laskin DM. Antibiotic pre-scribing habits of oral and maxillofacial surgeons in conjunction with routine
dental implant placement. J Oral Maxillofac Surgery 2015;73:1926-1931.
17. Froum SJ, Weinberg MA. An evaluation of antibiotic use in periodontal and implant practices. Int J Periodontics RestorativeDent
2015;35:481-487.

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Dental implant article " Dr chayon title: interventions for replacing missing teeth:dental implant, bacteria, antibiotics and infections around biomaterials,biofilm-a review.

  • 1. Title: Interventions for replacing missing teeth:dental implant, Bacteria, antibiotics and infections around biomaterials,biofilm-A review.
  • 2. Author :- Name: Dr. Aklaqur Rahman Chayon BDS. Dhaka Dental College.University of Dhaka, Mastership in dental Implantology (Mumbai) Senior Oral anatomy Lecturer (Department of oral anatomy and histology )DIDMC Co-author:- Dr Nurjahan Afsary nira BDS(University of Dhaka) Consultant Dental Surgeon AR Dental maxillofacial care research and training Center,N oral health and dental care,Banasree Dhaka.
  • 3. Abstract: Dental Implants have been shown to an excellent interventions for replacing missing teeth.Dental implant is a a biomaterials like natural teeth can be affected by microorganisms like bacteria which even,causes,peri-implantitis, peri-implant mucositis finally leads to implant failure.Dental implant are impervious to infections.In order to prevent infections antibiotics are shown to benefit in controlling infections,this review also seeks establish antibiotics are most effective during interventions of dental implant.There are many reasons for dental implant failure due to the develop of bacteremia is concern for dentists. This is due to the possibility of unfavorable result such as implant loss or lead to failure.
  • 4. Keywords: Biomaterials,Bacterial,Biofilm,antibiotic prophylaxis, clinical evidence, dental implants, implant placement, systematic review. Introduction:- Missing teeth can be usually replaced with dental implants in which a cap/crown,bridge or denture can be attached.During procedure Bacteria Can lead to infection and sometimes it may cause implant failure.Biomaterials (like -dental implant ) can be infected and hard to treat.Although implants are impervious to disease or infection.Supporting Gingivae and bone aren”t prone to ,Plaque,a Biofilm of a food and Bacteria that cultivate on tooth surface ,can causes infection : gingival diseases that weakens the supporting tissues of implant and implant itself.
  • 5.
  • 6.
  • 7.
  • 8. MATERIALS AND METHODS:- Review and meta-analysis, Literature data and analysis. DATA SOURCES: Literature Review ,Electronic databases,Pubmed, Cochrane, Science Direct, and EMBASE via OVID were searched up to September 2019. Only randomized controlled clinical trials (RCT) using antibiotics were included. Outcome measures were set on dental implant failures or postoperative infection incidence after dental implant surgery.
  • 9. Result :- Literature search and Quantitative studies :- In Data collections Fig- Showing the search results , From 1200 search results, 200 were excluded as they did not relate to human Studies , After that,643 citations were excluded because they were not clinical trials. 232 citations were discarded and excluded due to replica. Afterwards 125,studies which were 100 citations were excluded,mostly due to immue compromised patient ,dental conditions ,or no implant or no antibiotics .Finally 25 full articles for reviewing quantitative studies and results.
  • 10.
  • 11. CONCLUSIONS: Consequently,Scientific evidence suggests that, in general, antibiotics are beneficial for reducing failure of dental implants placed in ordinary conditions. It is still unknown whether postoperative antibiotics are beneficial, and which antibiotic is the most effective.
  • 12. References 1. Adell R, Lekholm U, Rockler B, Brånemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg 1981;10:387-416. 2. Tonetti MS, Schmid J. Pathogenesis of implant failures. Periodontol 2000 1994;4:127-38. Back to cited text no. 15. Quirynen M, Listgarten MA. Distribution of bacterial morphotypes around natural teeth and titanium implants ad modum Branemark. Clin Oral Implant Res 1990;1:8-12. 3. Apse P, Ellen RP, Overall CM, Zarb GA. Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: A comparison of sites in edentulous and partially edentulous patients. J Periodont Res 1989;24:96-105. Back to cited text no. 168. Albrektsson T, Isidor F. Consensus report. In: Lang NP, Karring T, editors. Proceedings of the 1 st European workshop on periodontology; 1994. p. 365-9. 4. Zitzmann NU, Berglundh T. Definition and prevalences of peri-implant diseases. J Clin Periodontol 2008;35:286-91. 5. Fransson C, Lekholm U, Jemt T, Berglundh T. Prevalence of subjects with progressive bone loss at implants. Clin Oral Implant Res 2005;16:440-6. 6. Fransson C, Wennstrom J, Berglundh T. Clinical characteristics at implants with a history of progressive bone loss. Clin Oral Implant Res 2008;19:142-7.
  • 13. 7. Karoussis IK, Salvi GE, Heitz-Mayfield L, Bragger J, Hammerle CH, Lang NP. Long-term implant prognosis in patients with and without a history of chronic periodontitis: A 10 year prospective cohort study of the ITI dental implant system. Clin Oral Implant Res 2003;14:329-39. 8. Roos-Jansaker AM, Lindahl C, Renvert H, Renvert S. Nine to Fourteen year follow-up of implant treatment. Part II: Presence of peri-implant lesions. J Clin Periodontol 2006;33:290-5. 9. Bragger U, Karaoussis I, Persson R, Pjetursson B, Salvi G, Lang N. Technical and biological complications/failures with single crowns and fixed partial dentures on implants. A 10 year prospective cohort study. Clin Oral Implant Res 2005;16:326-34. 10. Mombelli A, Van Oosten MA, Schruch E Jr, Land NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 1987;2:145-51.10. Hojo K, Nagaoka S, Oshima T. Bacterial interactions in dental biofilm development. J Dent Res. 2009;88:982–90. 11. Bassler BL, Wright M, Silverman MR. Multiple signaling systems controlling expressions of luminescence in Vibrio harveyi: Sequence and function of genes encoding a secondary sensory pathway. Mol Microbiology. 1994;13:273–86. 12. Rams TE, Link CC. Microbiology of failing dental implants in humans. Electron microscopic observation. J Oral Implantol. 1983;11:93– 100. 13. Haffajee AD, Cugini MA, Tanner A, Pollack RP, Smith C Kent RL Jr, Socransky SS. Subgingival microbiota in healthy, well- maintained elder and periodontitis subjects. J Clin Periodontol 1998;25:346-53. 14. Datta R, Grewal Y, Batth JS, Singh A. Current trend of antimi-crobial prescription for oral implant surgery among dentists in India. J Maxillofac Oral Surg 2014;13:503 -507. 15. Khalil D, Hultin M, Andersson Fred L, Parkbring Olsson N, Lund B. Antibiotic prescription patterns among Swedish dentists working with dental implant surgery: adherence to recommen-dations. Clin Oral Implant Res 2015;26:1064 -1069. 16. Deeb GR, Soung GY, Best AM, Laskin DM. Antibiotic pre-scribing habits of oral and maxillofacial surgeons in conjunction with routine dental implant placement. J Oral Maxillofac Surgery 2015;73:1926-1931. 17. Froum SJ, Weinberg MA. An evaluation of antibiotic use in periodontal and implant practices. Int J Periodontics RestorativeDent 2015;35:481-487.