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Multimodal analgesia and
opioids after hip surgery
Edward R. Mariano, M.D., M.A.S.
Professor of Anesthesiology, Perioperative & Pain Medicine
Stanford University School of Medicine
Chief, Anesthesiology and Perioperative Care
Veterans Affairs Palo Alto Health Care System
@EMARIANOMD
@EMARIANOMD
Disclosures
 None
@EMARIANOMD
The opioid epidemic
https://www.nytimes.com/interactive/2016/01/07/us/drug-overdose-deaths-in-the-us.html?_r=0
https://www.cdc.gov/drugoverdose/epidemic/index.html
@EMARIANOMD
@EMARIANOMD
@EMARIANOMD
Brummett, et al. JAMA 2017
Klueh, et al. JGIM 2018
The role of surgery
@EMARIANOMD
@EMARIANOMD
How long does pain last?
Mariano, El-Boghdadly, Ilfeld. Anaesthesia 2020
@EMARIANOMD
Postoperative pain varies by patient
TEMPOS Group (Tighe PJ). Anesthesiology 2021
@EMARIANOMD
@EMARIANOMD
Mariano, Schatman. J Pain Res 2019
@EMARIANOMD
@DrChadB
@EMARIANOMD
Tamboli, Mariano, et al. Pain Med 2019
@EMARIANOMD
@EMARIANOMD
@EMARIANOMD
Opportunities to improve
Mariano, Walters, Kim, Kain. A&A 2015
Walters, Mariano, Clark. Pain Med 2015
@EMARIANOMD
Goal to “personalise” pain medicine

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Multimodal analgesia and opioids after hip surgery