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NOMOS
Environmental Sanitizer




  VEDIC BIO SOURCE NOMOS
  Redefining Vector Control
Introduction


 •    Human development till date has always been enthroned upon the exclusivity of
      purpose and in the course the other related ecological aspects has always been
      down played upon.
 •    The devastating result we are facing when nature is trying to balance the imbalances
      we created.
 •    Use of chemicals is one major aspect which created a huge imbalance in the ecology
      to the extent that the existing species are mutating to a highly resistant and
      dangerous form posing serious threat to man kind.




 Alexander the great conquered the world but died of a mosquito Bite !
Nature carries within her self all the
solution of any problem

   •   On these line of thinking four ex-army officers with a scientific research oriented
       approach ventured into vector borne disease control and environmental sanitation
       control solution in 2006.
   •   ISHA LIFE NOMOS was started with this endeavor to find :

          •    Eco-Friendly
          •    Non-Toxic
          •    Non-Polluting
          •    Natural Vector Control Solution




Mosquitoes & Flies develop resistance to chemical based insecticides not to Nomos !
According to WHO and NVBDCP

  • Malaria kills over 1.2 million people annually
  • Dengue fever together with hemorrhagic fever is worlds fastest growing vector born
    disease.
  • Nearly half of the worlds population is infected with at least one type of vector born
    pathogen (CIESIN,2007; WHO,2004a)
  • Over the past 30yrs – following decades during which many mosquito born human
    illness were controlled in many areas through the use of habitat modification and
    pesticides ,Malaria and Dengue fever have re-emerged in Asia and Africa and emerged
    in Europe (Gubler,1998,2007;Roos,2007;Yergolkar et al. ,2006) .
  • According to national drug policy on malaria (2010) P.falciparum which causes 50% of
    the total malaria cases is resistant to chloroquine which is the main drug for first line
    treatment.
  • In second line treatment artemisinine based mono-therapy has been put off and
    combined therapy (ACT) has been made compulsory


  Patented ! Efficacious ! Safe!
ISSUES


     1     Disease burden due to vectors continue to rise.


     2     New emerging diseases unfold due to vectors


✓    3     Lack of pharmacological solutions


     4     Resistance developed in vectors


     5     Increased percentage use of chemicals


     6     Environmental issues due to the use of chemicals




    Mosquitoes & Flies develop resistance to chemical based insecticides!
ISSUES


 •   If we look at the history of vector control in India : The preDDT era included use of larvivorous fish oils and paris green in breeding
     sites.

 •   In 1944 DDT was introduced and tried in Assam Burma front in allied army camps of second world war with excellent results.

 •   Henceforth in 1953 National Malaria Control Programe(NMCP) was launched and riding on the success of it National Malaria
     Eradication Programe(NMEP) was launched in 1958.

 •   A set back to this program with resurgence of malaria happened in 1966 as An.culicifacies became resistant to DDT and HCH.

 •   Malathion and organophosphate insecticide was introduced in 1969 in Gujarat and Maharashtra and with in four years the species
     became resistant.

 •   In 1980 synthetic PYRETHROIDS, Deltamethrin was introduced and in the last decade of 20th century , Cyfluthrin and Lambda
     Cyhalothrin were introduced.

 •   Presently, insecticides belonging to different groups viz. ,organochlorine , organophosphate and synthetic pyrethyroid are used for
     public health sprays.

 •   You will be amazed to find An.culicifacies has developed resistance to all group of insecticides used so far in public health
     program.



     Dengue Existed then it Exists Now !
USE OF INSECTICIDES
    MAJOR PROBLEMS

1        Resistance



         Escalation in costs of development of new insecticide molecules
2



3        Associated hazards of human concern



4        Pesticide residues


         Despite the fact that governments across the world spend millions of dollars on vector control the reality is that the
5        problem is still not under control. Disease, morbidity and mortality rate continue to rise. Below poverty line people
         suffer the most due to non-affordability of personal repellents

         A major issue faced by the world is the resistance developed by these vectors to insecticides. Continuous and
6        prolonged use of chemicals make the new generations immune to the insecticide resulting in higher concentrations
         being used which further damages the environment besides being harmful and toxic to humans.




    Safe even for Infants ! You can actually drink it !
Health Hazards
Use Natural
  •    A survey carried out by the National Institute of Malaria Research, New Delhi, covering both
       users and medical practitioners in urban and rural areas in nine states of India found out:

  •    Mosquito repellents widely used in the country are harmful to health and suggests their use be
       avoided or discouraged

  •    11.8 % of the users of Synthetic Pyrethroids across all age groups and both sexes, "complained
       of a variety of acute toxicity effects either soon after or within a few hours of use of repellents of
       those using DEET-based cream”

  •    11.4 % reported skin reaction and itching.

  •    “Although symptoms disappear shortly after withdrawal, those who do not suffer acute toxicity and
       continue to use these repellents for extended periods may suffer neurotoxic and immunotoxic
       hazards”


Would you choose what‟s harmful for the mosquitoes, flies & you or only mosquitoes & flies ? Choose NOMOS !
Vector Control Market Failures


Challenges to providing new Vector insecticides:           Depletion of the Vector Control Arsenal
                                                           (adulticide)

         No new public health insecticides have                    The arsenal of safe and cost effective public
   1     been developed for mainstream vector control        2     health insecticide is being depleted by
         in last four decades.                                     restrictions for various reasons eg insecticide
                                                                   resistance, unacceptable side effects and non
                The small market for public health                 recognition.
                pesticides, contraction of agro
                chemical industry and loss of                      Resistance Issue
                commercial public health expertise
                have contributed to commercial                     Lack of suitable insecticides for Vector
                disengagement. As a result there is a              control in the Industry project portfolio.
                paucity of insecticide choices for
                public health use.                                            No contact action to mosquitoes
                Cost/Time to Develop a New                                    within the new class of
                Insecticide in Vector control                                 insecticides, (Fiproles, CNIs, etc.)
                € 70 m in a market of € 20 m                                  Fast KD, low tox, low rate, good
                Crop Protection Needed                                        residuality target profile needed.




Man is the biggest destroyer that exists on the planet !
Benefits of Nomos



✓    1     Administration de-burdened of control activities


✓    2     Long lasting non-toxic solution


✓    3     No resistance developed by insects

           Refreshed air
✓    4


✓    5     No expenses on insect repellants


✓    6     Less disease incidences




    Alexander the great conquered the world but died of a mosquito Bite !
Emergence of Solution


         Isha Life gone back to mother nature for vector control
✓   1    remedies.
         Product in the form of essential oils, extracted, purified and
✓   2    combined.

✓   3    Efficacious patented formulation

         International innovative Technology developed in India
✓   4

         Environment Sanitizing using natural essential oils which are
✓   5
         non-toxic and safe

✓   6    Does not harm any other mammal/ invertebrates.




To live a mosquito free life ! Choose what is natural !
Key Differentiators
       Chemical Based Insecticides Vs Envirofriendly Sanitizer




                         Chemical Insecticide                Nomos


         • Toxicity

         • Efficacy        Temporary

         • Solutions        Limited Areas            Cities,Institutions,Homes

         • ROI




Changing the dimensions of vector control- Nomos !
The Technology
Why Nomos ?

 Insects use receptors to identify food sources, mates and to be generally aware of the
 environment; insects typically have approximately 65 different olfactory receptors

 Five key receptor genes were isolated from American cockroach, fruit fly and mosquito

             Olfactory receptor genes (chemoreceptor genes) that are odor sensing
             Novel biogenic amine receptor genes that are neurotransmitters

 The genes were incorporated into model cells that mimic receptors in insects

 A screening process was developed using calcium ion and cAMP assays to quantitatively determine
     effectiveness of insecticides on model cells




     Completely Nontoxic !
The Technology
Why Nomos ?

 •   Receptors detect specific molecules that stimulate the insect to action
     (food, mating, etc) These volatile molecules bind temporarily to the receptor

 •   Natural plant essential oils contain molecules that may have a similar structure but
     bind permanently to the receptor

      – Cause the insect to be repelled (or at higher concentrations killed)

 •   Technology utilizes cloned insect chemo-receptor

      – Chosen receptors not found in mammals, focused toxicity on insects




     Completely Nontoxic !
NOMOS
     Clear Advantage Over Chemical Based Insecticides



             Mosquito free life




                Advantage
                 Nomos




                                         Our pledge to eradicate India of
               Deaths from               Mosquitoes Related death by 2017 and
             Dengue / Malaria
                                         the World of this scourge by 2020.



Nature is the manifestation of harmonic balance of existence- we pledge to make it liveable !
Nomos
Commercial Applications



 Vedic Bio Source realized the importance of reducing the „man-mosquito-contact‟ and
 developed a totally „Natural, Non-Toxic, Child Safe‟ vector/mosquito control cream based
 solution – NoMos Mosquito Repellent Cream. The cream offers protection from deadly
 disease causing mosquitoes such as; Aedes mosquito – which causes Dengue &
 Chikungunya and Anopheles mosquito – which causes Malaria.

 For use in Megacities, Houses, Village, Airports, Hospitals, Group
  Housing, Farms, Ships.



 Click on the box see Nomos Application




    Alexander the great conquered the world but died of a mosquito Bite !
Nomos
Commercial Applications

 Future products
 Vedic Bio Source will shortly be introducing various other naturally safe household & personal
 application products which are currently in various stages of development & registration. Such
 products will include:

   •   Hot & Cold vaporizer
   •   Anti Cockroach spray
   •   Anti Fly spray
   •   Head & Body Lice shampoo & cream
   •   Disinfectant floor wash
   •   Mosquito Repellent Incense Stick (Agarbatti)
   •   Skin illumination Anti-aging serum
   •   Antiseptic cream




 Would you choose what‟s harmful for the mosquitoes, flies & you or only mosquitoes & flies ? Choose NOMOS !
Nomos Products
   Consumer Durables / Home Solutions




Room Sanitizer        Perfume                      Cream                        Spray                    Nomos cream



      Synthetic chemical products have been the primary means for control of mosquito in homes and industries, and for
      personal health, but these products are often compromised by the development of mosquito resistance, environmental
      concerns, and adverse health effects in humans and animals. Vedic Bio Source‟s products are designed to overcome
      these issues.
Available Solution For Commerce




                                                       For Mega townships

                                                       For Premium Facilities
                                                        Hotels, Hospitals, Farm
                                                        Houses, Bungalows, Group Houses, Home
                                                        Securities

                                                       Travel With Nomos

                                                       Sanitizers Sprays

                                                       Home Sanitizer




   Man is the biggest destroyer that exists on the planet !
Our Evangelist Clients
Across the Country

                                                               Projects Undertaken



                                                                   Nagpur
                                   text
                                                                   Mumbai

                                                                   Bangalore

                                                                   Kerala

                                                                   Lakshadweep

                                                                   Badlapur
                                   text




    Man is the biggest destroyer that exists on the planet !
Contact US


                      Prime Options
                      The Marketing Genie !




                      Mail : [inquiry@primeoptions.in]
                      M : [+91-9717500111]
                            [+91-7827684048]
                      L    : [+91-124-4205699]
                      F    : [+91-124-4379086]




             THANK YOU!

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Nomos

  • 1. NOMOS Environmental Sanitizer VEDIC BIO SOURCE NOMOS Redefining Vector Control
  • 2. Introduction • Human development till date has always been enthroned upon the exclusivity of purpose and in the course the other related ecological aspects has always been down played upon. • The devastating result we are facing when nature is trying to balance the imbalances we created. • Use of chemicals is one major aspect which created a huge imbalance in the ecology to the extent that the existing species are mutating to a highly resistant and dangerous form posing serious threat to man kind. Alexander the great conquered the world but died of a mosquito Bite !
  • 3. Nature carries within her self all the solution of any problem • On these line of thinking four ex-army officers with a scientific research oriented approach ventured into vector borne disease control and environmental sanitation control solution in 2006. • ISHA LIFE NOMOS was started with this endeavor to find : • Eco-Friendly • Non-Toxic • Non-Polluting • Natural Vector Control Solution Mosquitoes & Flies develop resistance to chemical based insecticides not to Nomos !
  • 4. According to WHO and NVBDCP • Malaria kills over 1.2 million people annually • Dengue fever together with hemorrhagic fever is worlds fastest growing vector born disease. • Nearly half of the worlds population is infected with at least one type of vector born pathogen (CIESIN,2007; WHO,2004a) • Over the past 30yrs – following decades during which many mosquito born human illness were controlled in many areas through the use of habitat modification and pesticides ,Malaria and Dengue fever have re-emerged in Asia and Africa and emerged in Europe (Gubler,1998,2007;Roos,2007;Yergolkar et al. ,2006) . • According to national drug policy on malaria (2010) P.falciparum which causes 50% of the total malaria cases is resistant to chloroquine which is the main drug for first line treatment. • In second line treatment artemisinine based mono-therapy has been put off and combined therapy (ACT) has been made compulsory Patented ! Efficacious ! Safe!
  • 5. ISSUES 1 Disease burden due to vectors continue to rise. 2 New emerging diseases unfold due to vectors ✓ 3 Lack of pharmacological solutions 4 Resistance developed in vectors 5 Increased percentage use of chemicals 6 Environmental issues due to the use of chemicals Mosquitoes & Flies develop resistance to chemical based insecticides!
  • 6. ISSUES • If we look at the history of vector control in India : The preDDT era included use of larvivorous fish oils and paris green in breeding sites. • In 1944 DDT was introduced and tried in Assam Burma front in allied army camps of second world war with excellent results. • Henceforth in 1953 National Malaria Control Programe(NMCP) was launched and riding on the success of it National Malaria Eradication Programe(NMEP) was launched in 1958. • A set back to this program with resurgence of malaria happened in 1966 as An.culicifacies became resistant to DDT and HCH. • Malathion and organophosphate insecticide was introduced in 1969 in Gujarat and Maharashtra and with in four years the species became resistant. • In 1980 synthetic PYRETHROIDS, Deltamethrin was introduced and in the last decade of 20th century , Cyfluthrin and Lambda Cyhalothrin were introduced. • Presently, insecticides belonging to different groups viz. ,organochlorine , organophosphate and synthetic pyrethyroid are used for public health sprays. • You will be amazed to find An.culicifacies has developed resistance to all group of insecticides used so far in public health program. Dengue Existed then it Exists Now !
  • 7. USE OF INSECTICIDES MAJOR PROBLEMS 1 Resistance Escalation in costs of development of new insecticide molecules 2 3 Associated hazards of human concern 4 Pesticide residues Despite the fact that governments across the world spend millions of dollars on vector control the reality is that the 5 problem is still not under control. Disease, morbidity and mortality rate continue to rise. Below poverty line people suffer the most due to non-affordability of personal repellents A major issue faced by the world is the resistance developed by these vectors to insecticides. Continuous and 6 prolonged use of chemicals make the new generations immune to the insecticide resulting in higher concentrations being used which further damages the environment besides being harmful and toxic to humans. Safe even for Infants ! You can actually drink it !
  • 8. Health Hazards Use Natural • A survey carried out by the National Institute of Malaria Research, New Delhi, covering both users and medical practitioners in urban and rural areas in nine states of India found out: • Mosquito repellents widely used in the country are harmful to health and suggests their use be avoided or discouraged • 11.8 % of the users of Synthetic Pyrethroids across all age groups and both sexes, "complained of a variety of acute toxicity effects either soon after or within a few hours of use of repellents of those using DEET-based cream” • 11.4 % reported skin reaction and itching. • “Although symptoms disappear shortly after withdrawal, those who do not suffer acute toxicity and continue to use these repellents for extended periods may suffer neurotoxic and immunotoxic hazards” Would you choose what‟s harmful for the mosquitoes, flies & you or only mosquitoes & flies ? Choose NOMOS !
  • 9. Vector Control Market Failures Challenges to providing new Vector insecticides: Depletion of the Vector Control Arsenal (adulticide) No new public health insecticides have The arsenal of safe and cost effective public 1 been developed for mainstream vector control 2 health insecticide is being depleted by in last four decades. restrictions for various reasons eg insecticide resistance, unacceptable side effects and non The small market for public health recognition. pesticides, contraction of agro chemical industry and loss of Resistance Issue commercial public health expertise have contributed to commercial Lack of suitable insecticides for Vector disengagement. As a result there is a control in the Industry project portfolio. paucity of insecticide choices for public health use. No contact action to mosquitoes Cost/Time to Develop a New within the new class of Insecticide in Vector control insecticides, (Fiproles, CNIs, etc.) € 70 m in a market of € 20 m Fast KD, low tox, low rate, good Crop Protection Needed residuality target profile needed. Man is the biggest destroyer that exists on the planet !
  • 10. Benefits of Nomos ✓ 1 Administration de-burdened of control activities ✓ 2 Long lasting non-toxic solution ✓ 3 No resistance developed by insects Refreshed air ✓ 4 ✓ 5 No expenses on insect repellants ✓ 6 Less disease incidences Alexander the great conquered the world but died of a mosquito Bite !
  • 11. Emergence of Solution Isha Life gone back to mother nature for vector control ✓ 1 remedies. Product in the form of essential oils, extracted, purified and ✓ 2 combined. ✓ 3 Efficacious patented formulation International innovative Technology developed in India ✓ 4 Environment Sanitizing using natural essential oils which are ✓ 5 non-toxic and safe ✓ 6 Does not harm any other mammal/ invertebrates. To live a mosquito free life ! Choose what is natural !
  • 12. Key Differentiators Chemical Based Insecticides Vs Envirofriendly Sanitizer Chemical Insecticide Nomos • Toxicity • Efficacy Temporary • Solutions Limited Areas Cities,Institutions,Homes • ROI Changing the dimensions of vector control- Nomos !
  • 13. The Technology Why Nomos ? Insects use receptors to identify food sources, mates and to be generally aware of the environment; insects typically have approximately 65 different olfactory receptors Five key receptor genes were isolated from American cockroach, fruit fly and mosquito Olfactory receptor genes (chemoreceptor genes) that are odor sensing Novel biogenic amine receptor genes that are neurotransmitters The genes were incorporated into model cells that mimic receptors in insects A screening process was developed using calcium ion and cAMP assays to quantitatively determine effectiveness of insecticides on model cells Completely Nontoxic !
  • 14. The Technology Why Nomos ? • Receptors detect specific molecules that stimulate the insect to action (food, mating, etc) These volatile molecules bind temporarily to the receptor • Natural plant essential oils contain molecules that may have a similar structure but bind permanently to the receptor – Cause the insect to be repelled (or at higher concentrations killed) • Technology utilizes cloned insect chemo-receptor – Chosen receptors not found in mammals, focused toxicity on insects Completely Nontoxic !
  • 15. NOMOS Clear Advantage Over Chemical Based Insecticides Mosquito free life Advantage Nomos Our pledge to eradicate India of Deaths from Mosquitoes Related death by 2017 and Dengue / Malaria the World of this scourge by 2020. Nature is the manifestation of harmonic balance of existence- we pledge to make it liveable !
  • 16. Nomos Commercial Applications Vedic Bio Source realized the importance of reducing the „man-mosquito-contact‟ and developed a totally „Natural, Non-Toxic, Child Safe‟ vector/mosquito control cream based solution – NoMos Mosquito Repellent Cream. The cream offers protection from deadly disease causing mosquitoes such as; Aedes mosquito – which causes Dengue & Chikungunya and Anopheles mosquito – which causes Malaria. For use in Megacities, Houses, Village, Airports, Hospitals, Group Housing, Farms, Ships. Click on the box see Nomos Application Alexander the great conquered the world but died of a mosquito Bite !
  • 17. Nomos Commercial Applications Future products Vedic Bio Source will shortly be introducing various other naturally safe household & personal application products which are currently in various stages of development & registration. Such products will include: • Hot & Cold vaporizer • Anti Cockroach spray • Anti Fly spray • Head & Body Lice shampoo & cream • Disinfectant floor wash • Mosquito Repellent Incense Stick (Agarbatti) • Skin illumination Anti-aging serum • Antiseptic cream Would you choose what‟s harmful for the mosquitoes, flies & you or only mosquitoes & flies ? Choose NOMOS !
  • 18. Nomos Products Consumer Durables / Home Solutions Room Sanitizer Perfume Cream Spray Nomos cream Synthetic chemical products have been the primary means for control of mosquito in homes and industries, and for personal health, but these products are often compromised by the development of mosquito resistance, environmental concerns, and adverse health effects in humans and animals. Vedic Bio Source‟s products are designed to overcome these issues.
  • 19. Available Solution For Commerce  For Mega townships  For Premium Facilities Hotels, Hospitals, Farm Houses, Bungalows, Group Houses, Home Securities  Travel With Nomos  Sanitizers Sprays  Home Sanitizer Man is the biggest destroyer that exists on the planet !
  • 20. Our Evangelist Clients Across the Country Projects Undertaken  Nagpur text  Mumbai  Bangalore  Kerala  Lakshadweep  Badlapur text Man is the biggest destroyer that exists on the planet !
  • 21. Contact US Prime Options The Marketing Genie ! Mail : [inquiry@primeoptions.in] M : [+91-9717500111] [+91-7827684048] L : [+91-124-4205699] F : [+91-124-4379086] THANK YOU!