17. Major Levator Ani Defects : Case-Control Study of Pelvic Organ Prolapse Prolapse N=151 Normal N=134 Levator Ani Defects OR 7.3 DeLancey, et al. 2002, 2007
36. Genetics familiar transmission Pifarotti, IUGA 2008 Controls 90 Cases 124 P OR (CI) Mothers with POP (n/%) 12 (13%) 31 (25%) 0.039 2.2 (1.0-4.5) Sisters with POP (n/%) 3 (3%) 21 (17%) 0.002 5.9(1.7-20.5) All relatives with POP (n/%) 14 (16%) 43 (35%) 0.002 2.9 (1.5-5.7)
37.
38.
39. Conclusion Pelvic floor dysfunction, is a multifactorial and extremely common disorder in which genetic, endocrine and environmental factors may predispose to different clinical conditions including urinary incontinence, anal incontinence and pelvic organ prolapse.