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Fibreoptics
and
Cystoscopy
Dept of Urology
Govt Royapettah Hospital and Kilpauk Medical
College
Chennai
1
Moderators:
Professors:
• Prof. Dr. G. Sivasankar, M.S., M.Ch.,
• Prof. Dr. A. Senthilvel, M.S., M.Ch.,
Asst Professors:
• Dr. J. Sivabalan, M.S., M.Ch.,
• Dr. R. Bhargavi, M.S., M.Ch.,
• Dr. S. Raju, M.S., M.Ch.,
• Dr. K. Muthurathinam, M.S., M.Ch.,
• Dr. D. Tamilselvan, M.S., M.Ch.,
• Dr. K. Senthilkumar, M.S., M.Ch.
Dept Of Urology, KMC and GRH, Chennai 2
“No Aladdin’s cave was ever so beautiful or so full of surprises
as the human bladder.”
-John P Blandy, Operative Urology Textbook
Dept Of Urology, KMC and GRH, Chennai 3
Even though we take for granted the
present cystoscopy instruments, it is
only through the efforts of many
pioneers we enjoy them.
Our present day equipment is merely
a forerunner of what the future will
bring.
Dept Of Urology, KMC and GRH, Chennai 4
Cystoscopy-Evolution
Dept Of Urology, KMC and GRH, Chennai 5
First Generation Cystoscopes
• How to light a cave?
• How to see the light from
outside?
Dept Of Urology, KMC and GRH, Chennai 6
Phillip Bozzini- ‘Leichleiter’ or Guide light
1806
Dept Of Urology, KMC and GRH, Chennai 7
Bozzini Cystoscope-Optics
Dept Of Urology, KMC and GRH, Chennai 8
Vienna Faculty of Medicine-Perverse Curiosity
• Wax candle with chimney
• Shark skin
• Concave lens
Dept Of Urology, KMC and GRH, Chennai 9
Pierre Segalas –Urethro cystique-1826
Dept Of Urology, KMC and GRH, Chennai 10
John Dix Fisher - 1826
Dept Of Urology, KMC and GRH, Chennai 11
Antonie Desormeaux-1853
Dept Of Urology, KMC and GRH, Chennai 12
Desormaeux-Optics
• Kerosene Light
• Adjustable mirror
Dept Of Urology, KMC and GRH, Chennai 13
Desormaeux-Father of Cystoscopy
• First Endosurgery-
Urethral Papilloma
excision
• Coined the term
‘Endoscope’.
Dept Of Urology, KMC and GRH, Chennai 14
Second Generation Cystoscopes
• Advent of Electricity
• Intracorporeal Light sources
• Increased Field of vision
Dept Of Urology, KMC and GRH, Chennai 15
Maximilian Nitze-1877
Father of Modern Urology
“In order to light up
the Room, you have
to carry the light
inside”
Dept Of Urology, KMC and GRH, Chennai 16
Problems with 1st Gen Cystoscopes
• Poor Illumination – Use Bruck’s Platinum wire
• Minuteness of Image – Use Prisms and Lenses (in collaboration with
Joseph Leiter from Vienna)
Dept Of Urology, KMC and GRH, Chennai 17
Bruck’s Apparatus – Hot light source
When electricity is passed through a
platinum wire, it produced intense heat and
white glow, which can be used as light
source.
Dept Of Urology, KMC and GRH, Chennai 18
Nitze Cystoscope-With Platinum Wire
Dept Of Urology, KMC and GRH, Chennai 19
Nitze Endoscope – Minuteness of Image
Dept Of Urology, KMC and GRH, Chennai 20
Nitze-Leiter Cystoscope-1879
Dept Of Urology, KMC and GRH, Chennai 21
‘Box Phantom’ of Valentine
Dept Of Urology, KMC and GRH, Chennai 22
Problems with 2nd Gen Cystoscopes
• Heavy equipment
• Burns to the patient and the surgeon
• Platinum is easily fused
• Mirrored and inverted image
Dept Of Urology, KMC and GRH, Chennai 23
Third Generation Cystoscopes
• Cold light source
• Unmirrored erect image
Dept Of Urology, KMC and GRH, Chennai 24
Third generation Cystoscope-Cold Light
• In the Year 1878
• Electric current passed
through carbon fibre in
vacuum will produce
light.
• It will neither produce
much heat nor will burn
out.
Dept Of Urology, KMC and GRH, Chennai 25
Nitze-Leiter Cystoscope-1900s
Dept Of Urology, KMC and GRH, Chennai 26
Air cystoscopy-Howard Kelly-1892
Dept Of Urology, KMC and GRH, Chennai 27
Air distension cystoscopes-American Standard
Dept Of Urology, KMC and GRH, Chennai 28
Problems
• Irritates the bladder mucosa
• Urine collected during procedure cause air bubbles and false images
• Air embolism in rare cases
Any reason?
Early endoscopes had no way to instill water through separate channel
Sterlising urological instruments was difficult.
Getting sterile water for irrigation was very difficult.
Dept Of Urology, KMC and GRH, Chennai 29
Fourth Generation Cystoscope
• Hopkins Rod lens
• Fibre Optics
Dept Of Urology, KMC and GRH, Chennai 30
Harold Hopkins-SEFLOC glass lens
Dept Of Urology, KMC and GRH, Chennai 31
Hopkins Vs Older Lens systems
Dept Of Urology, KMC and GRH, Chennai 32
Total Internal Reflection
Dept Of Urology, KMC and GRH, Chennai 33
Optical Fibre Principle
Dept Of Urology, KMC and GRH, Chennai 34
Heinrich Lamm-1903-Medical Student
• Light can be bent as it pass through the glass
fibre.
• Bunch of glass fibres can be used to transmit
an image and reproduce again at a distance.
• Applied for patent but denied because of
poor image quality.
Dept Of Urology, KMC and GRH, Chennai 35
Hopkins and Narinder Kapany-1948
• Physicist Harold Hopkins and his graduate
student Narinder Kapany improved image
resolution by increasing the number of
fibers in a bundle and got patent for the
same.
• Father of Fibreoptics-Dr.Narinder Kapany
Dept Of Urology, KMC and GRH, Chennai 36
Combining Hopkins and Optic fibre –
Karl Storz – German Company with American Brain
Dept Of Urology, KMC and GRH, Chennai 37
Hopkins And Van Heel
Dept Of Urology, KMC and GRH, Chennai 38
Fifth Generation Cystoscope
• Video Imaging
Dept Of Urology, KMC and GRH, Chennai 39
Photoelectric effect
Dept Of Urology, KMC and GRH, Chennai 40
RGB and Photoelectric Effect
Dept Of Urology, KMC and GRH, Chennai 41
Charged Couple Device-CCD-1969
Dept Of Urology, KMC and GRH, Chennai 42
Recent Advances
• Narrow Band Imaging
• Photodynamic diagnosis/Blue light imaging
• Confocal Laser endomicroscopy
• Optical Coherence Tomography
Dept Of Urology, KMC and GRH, Chennai 43
Narrow Band Imaging
• This optical technology uses a CCD chip and a special filter.
• Basic Principles:
• Used primarily for identifying superficial lesions.
• Blue light has less penetration.
• Hemoglobin absorbs blue and light avidly.
• Malignancy are more vascular hence more hemoglobin.
Dept Of Urology, KMC and GRH, Chennai 44
Narrow Band Imaging Technique
Dept Of Urology, KMC and GRH, Chennai 45
Colour Coding
Dept Of Urology, KMC and GRH, Chennai 46
Narrow Band Imaging
Dept Of Urology, KMC and GRH, Chennai 47
Photodynamic diagnosis/Blue light imaging
• Based on the concept of Flourescence.
Dept Of Urology, KMC and GRH, Chennai 48
Flourescence Principle
Dept Of Urology, KMC and GRH, Chennai 49
Visible Light Spectrum
• Wavelengh of Blue higher
than Red.
• Blue is higher energy wave
and Red is lower energy.
Dept Of Urology, KMC and GRH, Chennai 50
Blue light Cystoscopy
• Amino levulinic acid is a fluorescent agent.
• It is absorbed by dysplastic tissue but not by normal tissue.
• If blue light is used for illumination, ALA will absorb blue and it will
emit red light.
• So against a blue background, the tumour will be red.
Dept Of Urology, KMC and GRH, Chennai 51
Blue light imaging
Dept Of Urology, KMC and GRH, Chennai 52
Confocal Laser Endomicroscopy
• Based on Flourescence.
• Flourescein dye is used and images are
taken 30 sec to 8 minutes after the
procedure.
• It permeates the lamina propria and
extracellular matrix.
• Architectural distortion noted.
• Also known as Optical Biopsy.
Dept Of Urology, KMC and GRH, Chennai 53
Confocal Laser Endomicroscopy
Dept Of Urology, KMC and GRH, Chennai 54
Optical Coherence Tomography (OCT)
• Non-invasive optical technique to see below the surface of tissues (up
to 1–3 mm).
• This technology is similar to ultrasound except that OCT provides
much higher resolution images.
• It measures reflected waves of near infrared light.
• Does not require direct contact with the tissues.
Dept Of Urology, KMC and GRH, Chennai 55
Resolution and Penetration-Comparison
Dept Of Urology, KMC and GRH, Chennai 56
Optical Coherence Tomography
• Lamina propria has a “bright, distinct
signal” while the muscularis had a
“darker, spindled appearance”.
• Muscle invasion can be detected
with OCT.
Dept Of Urology, KMC and GRH, Chennai 57
OCT-Limitations
• Steep learning curve for interpretation by the surgeon
• False positives that can occur with other conditions that disturb the
urothelial layers such as scarring or inflammation.
Dept Of Urology, KMC and GRH, Chennai 58
Rigid
Cystoscopy
Dept Of Urology, KMC and GRH, Chennai 59
Rigid Cystoscope Components
1. Cystoscope sheath
2. Cystoscope obturator
3. Bridge
4. Light cable
5. Telescope
Dept Of Urology, KMC and GRH, Chennai 60
Cystoscope Sheath
• All cystoscopes are made of stainless steel alloy.
• The cystoscope sheath is calibrated in French (Fr), this is considered
to be the outer circumference of the instrument in millimeters (mm).
Fr is same as Charriere (Ch).
Dept Of Urology, KMC and GRH, Chennai 61
Cystoscope Sheath
• Adult sheath-22 cms. Cross section-Oval
• No markings for distal 10cm, later marking every 1 cm for 13 cms.
• Useful for measuring Prostatic urethral length.
• Vesical end of 17Fr is different from all others.
Dept Of Urology, KMC and GRH, Chennai 62
Cystoscope Sheath
• At the level of inlet/outlet channel –Sheath size
• Behind sheath size, largest size of the catheter, two
of which can be passed simultaneously.
• Behind the above - single largest catheter, which
can be passed through the sheath.
• The above catheter size are the maximum size with
scope and Albarrans lever in situ.
• If simple bridge is used maximal permissible
catheter size will increase by 1 Fr.
Dept Of Urology, KMC and GRH, Chennai 63
Albarran’s Lever
• It is Bridge with a deflecting lever, which can be used to deflect the
ureteric catheter to align the catheter with the ureteric orifice.
• It has two channels through which two catheters can be passed
simultaneously.
Dept Of Urology, KMC and GRH, Chennai 64
Cystoscope Bridge
• Adult cystoscope bridges are universal and can fit into all sizes of
sheaths. Length of bridge is 6 cm.
• Telescope channel: It accommodates the telescope.
• Accessories’ channel: It is meant to pass the accessories such as
ureteric catheter, wires forceps, etc.
Dept Of Urology, KMC and GRH, Chennai 65
Obturators
• They are specific for a given sheath.
• Once attached to the sheath it makes the tip of the sheath smooth
thereby snuggly fitting to it.
• The length of the obturator is 26 cm.
Dept Of Urology, KMC and GRH, Chennai 66
Obturator-Parts
Vesical end knob: This helps in smooth atraumatic insertion of the
cystoscope.
Shaft: Connects the vesical end knob and the locking mechanism.
Locking mechanism: Zero (0) should correspond to zero (0) of the
sheath when locked.
Dept Of Urology, KMC and GRH, Chennai 67
Obturator-Differentiation
Dept Of Urology, KMC and GRH, Chennai 68
Telescopes
• The telescopes are classified depending on the viewing angle. They
are available as 0°, 30°, 70°, 120° and 12°.
• Straight forward telescopes (0°) is focused to view straight ahead, is
usually used for urethroscopy.
• Forward oblique telescopes (30°) best affords visualization of the base
and anterolateral aspect of the bladder, this is the most commonly
used telescope.
• Lateral telescope (70°) to view the bladder dome.
Dept Of Urology, KMC and GRH, Chennai 69
Telescope-Colour Coding
Dept Of Urology, KMC and GRH, Chennai 70
Positioning
• Lies flat with legs supported
on rests so that the thigh
makes an angle of 10 to 20
degrees with the horizontal.
• If the angle is steep, it is
difficult to examine trigone or
ureter catheterization.
• Supine with legs placed apart
on a padded rest is an
alternative.
Dept Of Urology, KMC and GRH, Chennai 71
Preparation
• Skin preparation can be done with
betadine or chlorhexidine solution.
• Urethra is gently injected with
anaesthetic lubricant gel.
• Penile clamp is applied
transversely proximal to the glans
penis.
Dept Of Urology, KMC and GRH, Chennai 72
Technique
• In introducing cystoscope, under direct
vision, with irrigation on flow, follow the
curve of the urethra, swinging the
instrument downwards round the bulbar
urethra.
• Force is never needed.
Dept Of Urology, KMC and GRH, Chennai 73
Physiological Narrowings
1. Internal Meatus
2. Navicular fossa to penile urethra
proper transition
3. Penile urethra
4. Bulbar urethra to membranous
urethra transition
Dept Of Urology, KMC and GRH, Chennai 74
Urethra Curvatures
1. Penoscrotal angle (Straighten the
Penis)
2. Curvature in the bulb (Swing the
scope downwards)
3. Ventral curvature of due to median
lobe (Inconsistent)
Dept Of Urology, KMC and GRH, Chennai 75
Anterior and Bulbar urethra
• Anterior urethra may have few
openings of urethral glands,
sometimes more prominent near
bulb.
• Bulbar urethra becomes wider,
shows helical submucosal rings
like the barrel of a rifle.
• Follow the roof of the urethra and
swing the urethroscope down
gently until the external sphinter
is seen.
Dept Of Urology, KMC and GRH, Chennai 76
External Sphincter
• External sphincter looks like the
anus, occluding the lumen.
• But it easily dilates before
advancing the endoscope.
• If the patient is frightened, it may
be difficult to relax.
• Ask the patient to breathe in and
out deeply or pretend to urinate.
Dept Of Urology, KMC and GRH, Chennai 77
Prostatic Urethra
• Normal prostatic urethra is red and
granular.
• Verumontanum is the salient feature
of prostatic urethra. It has a central pit
called Utriculus masculinus.
• Opening on either side of the utriculus
are the orifices of the ejaculatory
ducts.
• On the proximal end is the bladder
neck, once crossed, it reaches bladder.
Dept Of Urology, KMC and GRH, Chennai 78
Ureteric Orifices
• The cystoscope is advanced 2 cm inwards from the bladder neck and
then rotated 45 degrees first on one side and then on the other.
• Interureteric ridge is a useful landmark.
Dept Of Urology, KMC and GRH, Chennai 79
Flexible
Cystoscopy
Dept Of Urology, KMC and GRH, Chennai 80
Cross section Image
• Two light guide
• bundles
• One image guide bundle
• Working channel
Dept Of Urology, KMC and GRH, Chennai 81
Technique
• Supine position with legs apart.
• Penis cleaned with antiseptic solution.
• Anaesthetic jelly injected.
• Flexible endoscope is advanced while sterile water flows through it
under direct vision.
• As the external sphincter is approached, the tip is slightly bent up.
• Patient is asked to pretend to void.
• Sphincter relaxes and the scope slides into prostatic urethra.
Dept Of Urology, KMC and GRH, Chennai 82
Technique
• The scope is advanced after examining the prostatic urethra into the
bladder.
• All bladder walls are examined systematically.
• Finally, by curving the tip fully open itself, retrograde view of the
bladder neck can be achieved.
Dept Of Urology, KMC and GRH, Chennai 83
Advantages
• Ease in patient positioning resulting in better patient comfort.
• It is useful in manipulation across difficult curves and high bladder
necks and median lobes.
• The ability to flex the endoscope helps in complete visualization of
the bladder easily.
Dept Of Urology, KMC and GRH, Chennai 84
Thank You
Dept Of Urology, KMC and GRH, Chennai 85

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Uro instruments- cystoscopy & fibreoptics

  • 1. Fibreoptics and Cystoscopy Dept of Urology Govt Royapettah Hospital and Kilpauk Medical College Chennai 1
  • 2. Moderators: Professors: • Prof. Dr. G. Sivasankar, M.S., M.Ch., • Prof. Dr. A. Senthilvel, M.S., M.Ch., Asst Professors: • Dr. J. Sivabalan, M.S., M.Ch., • Dr. R. Bhargavi, M.S., M.Ch., • Dr. S. Raju, M.S., M.Ch., • Dr. K. Muthurathinam, M.S., M.Ch., • Dr. D. Tamilselvan, M.S., M.Ch., • Dr. K. Senthilkumar, M.S., M.Ch. Dept Of Urology, KMC and GRH, Chennai 2
  • 3. “No Aladdin’s cave was ever so beautiful or so full of surprises as the human bladder.” -John P Blandy, Operative Urology Textbook Dept Of Urology, KMC and GRH, Chennai 3
  • 4. Even though we take for granted the present cystoscopy instruments, it is only through the efforts of many pioneers we enjoy them. Our present day equipment is merely a forerunner of what the future will bring. Dept Of Urology, KMC and GRH, Chennai 4
  • 5. Cystoscopy-Evolution Dept Of Urology, KMC and GRH, Chennai 5
  • 6. First Generation Cystoscopes • How to light a cave? • How to see the light from outside? Dept Of Urology, KMC and GRH, Chennai 6
  • 7. Phillip Bozzini- ‘Leichleiter’ or Guide light 1806 Dept Of Urology, KMC and GRH, Chennai 7
  • 8. Bozzini Cystoscope-Optics Dept Of Urology, KMC and GRH, Chennai 8
  • 9. Vienna Faculty of Medicine-Perverse Curiosity • Wax candle with chimney • Shark skin • Concave lens Dept Of Urology, KMC and GRH, Chennai 9
  • 10. Pierre Segalas –Urethro cystique-1826 Dept Of Urology, KMC and GRH, Chennai 10
  • 11. John Dix Fisher - 1826 Dept Of Urology, KMC and GRH, Chennai 11
  • 12. Antonie Desormeaux-1853 Dept Of Urology, KMC and GRH, Chennai 12
  • 13. Desormaeux-Optics • Kerosene Light • Adjustable mirror Dept Of Urology, KMC and GRH, Chennai 13
  • 14. Desormaeux-Father of Cystoscopy • First Endosurgery- Urethral Papilloma excision • Coined the term ‘Endoscope’. Dept Of Urology, KMC and GRH, Chennai 14
  • 15. Second Generation Cystoscopes • Advent of Electricity • Intracorporeal Light sources • Increased Field of vision Dept Of Urology, KMC and GRH, Chennai 15
  • 16. Maximilian Nitze-1877 Father of Modern Urology “In order to light up the Room, you have to carry the light inside” Dept Of Urology, KMC and GRH, Chennai 16
  • 17. Problems with 1st Gen Cystoscopes • Poor Illumination – Use Bruck’s Platinum wire • Minuteness of Image – Use Prisms and Lenses (in collaboration with Joseph Leiter from Vienna) Dept Of Urology, KMC and GRH, Chennai 17
  • 18. Bruck’s Apparatus – Hot light source When electricity is passed through a platinum wire, it produced intense heat and white glow, which can be used as light source. Dept Of Urology, KMC and GRH, Chennai 18
  • 19. Nitze Cystoscope-With Platinum Wire Dept Of Urology, KMC and GRH, Chennai 19
  • 20. Nitze Endoscope – Minuteness of Image Dept Of Urology, KMC and GRH, Chennai 20
  • 21. Nitze-Leiter Cystoscope-1879 Dept Of Urology, KMC and GRH, Chennai 21
  • 22. ‘Box Phantom’ of Valentine Dept Of Urology, KMC and GRH, Chennai 22
  • 23. Problems with 2nd Gen Cystoscopes • Heavy equipment • Burns to the patient and the surgeon • Platinum is easily fused • Mirrored and inverted image Dept Of Urology, KMC and GRH, Chennai 23
  • 24. Third Generation Cystoscopes • Cold light source • Unmirrored erect image Dept Of Urology, KMC and GRH, Chennai 24
  • 25. Third generation Cystoscope-Cold Light • In the Year 1878 • Electric current passed through carbon fibre in vacuum will produce light. • It will neither produce much heat nor will burn out. Dept Of Urology, KMC and GRH, Chennai 25
  • 26. Nitze-Leiter Cystoscope-1900s Dept Of Urology, KMC and GRH, Chennai 26
  • 27. Air cystoscopy-Howard Kelly-1892 Dept Of Urology, KMC and GRH, Chennai 27
  • 28. Air distension cystoscopes-American Standard Dept Of Urology, KMC and GRH, Chennai 28
  • 29. Problems • Irritates the bladder mucosa • Urine collected during procedure cause air bubbles and false images • Air embolism in rare cases Any reason? Early endoscopes had no way to instill water through separate channel Sterlising urological instruments was difficult. Getting sterile water for irrigation was very difficult. Dept Of Urology, KMC and GRH, Chennai 29
  • 30. Fourth Generation Cystoscope • Hopkins Rod lens • Fibre Optics Dept Of Urology, KMC and GRH, Chennai 30
  • 31. Harold Hopkins-SEFLOC glass lens Dept Of Urology, KMC and GRH, Chennai 31
  • 32. Hopkins Vs Older Lens systems Dept Of Urology, KMC and GRH, Chennai 32
  • 33. Total Internal Reflection Dept Of Urology, KMC and GRH, Chennai 33
  • 34. Optical Fibre Principle Dept Of Urology, KMC and GRH, Chennai 34
  • 35. Heinrich Lamm-1903-Medical Student • Light can be bent as it pass through the glass fibre. • Bunch of glass fibres can be used to transmit an image and reproduce again at a distance. • Applied for patent but denied because of poor image quality. Dept Of Urology, KMC and GRH, Chennai 35
  • 36. Hopkins and Narinder Kapany-1948 • Physicist Harold Hopkins and his graduate student Narinder Kapany improved image resolution by increasing the number of fibers in a bundle and got patent for the same. • Father of Fibreoptics-Dr.Narinder Kapany Dept Of Urology, KMC and GRH, Chennai 36
  • 37. Combining Hopkins and Optic fibre – Karl Storz – German Company with American Brain Dept Of Urology, KMC and GRH, Chennai 37
  • 38. Hopkins And Van Heel Dept Of Urology, KMC and GRH, Chennai 38
  • 39. Fifth Generation Cystoscope • Video Imaging Dept Of Urology, KMC and GRH, Chennai 39
  • 40. Photoelectric effect Dept Of Urology, KMC and GRH, Chennai 40
  • 41. RGB and Photoelectric Effect Dept Of Urology, KMC and GRH, Chennai 41
  • 42. Charged Couple Device-CCD-1969 Dept Of Urology, KMC and GRH, Chennai 42
  • 43. Recent Advances • Narrow Band Imaging • Photodynamic diagnosis/Blue light imaging • Confocal Laser endomicroscopy • Optical Coherence Tomography Dept Of Urology, KMC and GRH, Chennai 43
  • 44. Narrow Band Imaging • This optical technology uses a CCD chip and a special filter. • Basic Principles: • Used primarily for identifying superficial lesions. • Blue light has less penetration. • Hemoglobin absorbs blue and light avidly. • Malignancy are more vascular hence more hemoglobin. Dept Of Urology, KMC and GRH, Chennai 44
  • 45. Narrow Band Imaging Technique Dept Of Urology, KMC and GRH, Chennai 45
  • 46. Colour Coding Dept Of Urology, KMC and GRH, Chennai 46
  • 47. Narrow Band Imaging Dept Of Urology, KMC and GRH, Chennai 47
  • 48. Photodynamic diagnosis/Blue light imaging • Based on the concept of Flourescence. Dept Of Urology, KMC and GRH, Chennai 48
  • 49. Flourescence Principle Dept Of Urology, KMC and GRH, Chennai 49
  • 50. Visible Light Spectrum • Wavelengh of Blue higher than Red. • Blue is higher energy wave and Red is lower energy. Dept Of Urology, KMC and GRH, Chennai 50
  • 51. Blue light Cystoscopy • Amino levulinic acid is a fluorescent agent. • It is absorbed by dysplastic tissue but not by normal tissue. • If blue light is used for illumination, ALA will absorb blue and it will emit red light. • So against a blue background, the tumour will be red. Dept Of Urology, KMC and GRH, Chennai 51
  • 52. Blue light imaging Dept Of Urology, KMC and GRH, Chennai 52
  • 53. Confocal Laser Endomicroscopy • Based on Flourescence. • Flourescein dye is used and images are taken 30 sec to 8 minutes after the procedure. • It permeates the lamina propria and extracellular matrix. • Architectural distortion noted. • Also known as Optical Biopsy. Dept Of Urology, KMC and GRH, Chennai 53
  • 54. Confocal Laser Endomicroscopy Dept Of Urology, KMC and GRH, Chennai 54
  • 55. Optical Coherence Tomography (OCT) • Non-invasive optical technique to see below the surface of tissues (up to 1–3 mm). • This technology is similar to ultrasound except that OCT provides much higher resolution images. • It measures reflected waves of near infrared light. • Does not require direct contact with the tissues. Dept Of Urology, KMC and GRH, Chennai 55
  • 56. Resolution and Penetration-Comparison Dept Of Urology, KMC and GRH, Chennai 56
  • 57. Optical Coherence Tomography • Lamina propria has a “bright, distinct signal” while the muscularis had a “darker, spindled appearance”. • Muscle invasion can be detected with OCT. Dept Of Urology, KMC and GRH, Chennai 57
  • 58. OCT-Limitations • Steep learning curve for interpretation by the surgeon • False positives that can occur with other conditions that disturb the urothelial layers such as scarring or inflammation. Dept Of Urology, KMC and GRH, Chennai 58
  • 59. Rigid Cystoscopy Dept Of Urology, KMC and GRH, Chennai 59
  • 60. Rigid Cystoscope Components 1. Cystoscope sheath 2. Cystoscope obturator 3. Bridge 4. Light cable 5. Telescope Dept Of Urology, KMC and GRH, Chennai 60
  • 61. Cystoscope Sheath • All cystoscopes are made of stainless steel alloy. • The cystoscope sheath is calibrated in French (Fr), this is considered to be the outer circumference of the instrument in millimeters (mm). Fr is same as Charriere (Ch). Dept Of Urology, KMC and GRH, Chennai 61
  • 62. Cystoscope Sheath • Adult sheath-22 cms. Cross section-Oval • No markings for distal 10cm, later marking every 1 cm for 13 cms. • Useful for measuring Prostatic urethral length. • Vesical end of 17Fr is different from all others. Dept Of Urology, KMC and GRH, Chennai 62
  • 63. Cystoscope Sheath • At the level of inlet/outlet channel –Sheath size • Behind sheath size, largest size of the catheter, two of which can be passed simultaneously. • Behind the above - single largest catheter, which can be passed through the sheath. • The above catheter size are the maximum size with scope and Albarrans lever in situ. • If simple bridge is used maximal permissible catheter size will increase by 1 Fr. Dept Of Urology, KMC and GRH, Chennai 63
  • 64. Albarran’s Lever • It is Bridge with a deflecting lever, which can be used to deflect the ureteric catheter to align the catheter with the ureteric orifice. • It has two channels through which two catheters can be passed simultaneously. Dept Of Urology, KMC and GRH, Chennai 64
  • 65. Cystoscope Bridge • Adult cystoscope bridges are universal and can fit into all sizes of sheaths. Length of bridge is 6 cm. • Telescope channel: It accommodates the telescope. • Accessories’ channel: It is meant to pass the accessories such as ureteric catheter, wires forceps, etc. Dept Of Urology, KMC and GRH, Chennai 65
  • 66. Obturators • They are specific for a given sheath. • Once attached to the sheath it makes the tip of the sheath smooth thereby snuggly fitting to it. • The length of the obturator is 26 cm. Dept Of Urology, KMC and GRH, Chennai 66
  • 67. Obturator-Parts Vesical end knob: This helps in smooth atraumatic insertion of the cystoscope. Shaft: Connects the vesical end knob and the locking mechanism. Locking mechanism: Zero (0) should correspond to zero (0) of the sheath when locked. Dept Of Urology, KMC and GRH, Chennai 67
  • 69. Telescopes • The telescopes are classified depending on the viewing angle. They are available as 0°, 30°, 70°, 120° and 12°. • Straight forward telescopes (0°) is focused to view straight ahead, is usually used for urethroscopy. • Forward oblique telescopes (30°) best affords visualization of the base and anterolateral aspect of the bladder, this is the most commonly used telescope. • Lateral telescope (70°) to view the bladder dome. Dept Of Urology, KMC and GRH, Chennai 69
  • 70. Telescope-Colour Coding Dept Of Urology, KMC and GRH, Chennai 70
  • 71. Positioning • Lies flat with legs supported on rests so that the thigh makes an angle of 10 to 20 degrees with the horizontal. • If the angle is steep, it is difficult to examine trigone or ureter catheterization. • Supine with legs placed apart on a padded rest is an alternative. Dept Of Urology, KMC and GRH, Chennai 71
  • 72. Preparation • Skin preparation can be done with betadine or chlorhexidine solution. • Urethra is gently injected with anaesthetic lubricant gel. • Penile clamp is applied transversely proximal to the glans penis. Dept Of Urology, KMC and GRH, Chennai 72
  • 73. Technique • In introducing cystoscope, under direct vision, with irrigation on flow, follow the curve of the urethra, swinging the instrument downwards round the bulbar urethra. • Force is never needed. Dept Of Urology, KMC and GRH, Chennai 73
  • 74. Physiological Narrowings 1. Internal Meatus 2. Navicular fossa to penile urethra proper transition 3. Penile urethra 4. Bulbar urethra to membranous urethra transition Dept Of Urology, KMC and GRH, Chennai 74
  • 75. Urethra Curvatures 1. Penoscrotal angle (Straighten the Penis) 2. Curvature in the bulb (Swing the scope downwards) 3. Ventral curvature of due to median lobe (Inconsistent) Dept Of Urology, KMC and GRH, Chennai 75
  • 76. Anterior and Bulbar urethra • Anterior urethra may have few openings of urethral glands, sometimes more prominent near bulb. • Bulbar urethra becomes wider, shows helical submucosal rings like the barrel of a rifle. • Follow the roof of the urethra and swing the urethroscope down gently until the external sphinter is seen. Dept Of Urology, KMC and GRH, Chennai 76
  • 77. External Sphincter • External sphincter looks like the anus, occluding the lumen. • But it easily dilates before advancing the endoscope. • If the patient is frightened, it may be difficult to relax. • Ask the patient to breathe in and out deeply or pretend to urinate. Dept Of Urology, KMC and GRH, Chennai 77
  • 78. Prostatic Urethra • Normal prostatic urethra is red and granular. • Verumontanum is the salient feature of prostatic urethra. It has a central pit called Utriculus masculinus. • Opening on either side of the utriculus are the orifices of the ejaculatory ducts. • On the proximal end is the bladder neck, once crossed, it reaches bladder. Dept Of Urology, KMC and GRH, Chennai 78
  • 79. Ureteric Orifices • The cystoscope is advanced 2 cm inwards from the bladder neck and then rotated 45 degrees first on one side and then on the other. • Interureteric ridge is a useful landmark. Dept Of Urology, KMC and GRH, Chennai 79
  • 80. Flexible Cystoscopy Dept Of Urology, KMC and GRH, Chennai 80
  • 81. Cross section Image • Two light guide • bundles • One image guide bundle • Working channel Dept Of Urology, KMC and GRH, Chennai 81
  • 82. Technique • Supine position with legs apart. • Penis cleaned with antiseptic solution. • Anaesthetic jelly injected. • Flexible endoscope is advanced while sterile water flows through it under direct vision. • As the external sphincter is approached, the tip is slightly bent up. • Patient is asked to pretend to void. • Sphincter relaxes and the scope slides into prostatic urethra. Dept Of Urology, KMC and GRH, Chennai 82
  • 83. Technique • The scope is advanced after examining the prostatic urethra into the bladder. • All bladder walls are examined systematically. • Finally, by curving the tip fully open itself, retrograde view of the bladder neck can be achieved. Dept Of Urology, KMC and GRH, Chennai 83
  • 84. Advantages • Ease in patient positioning resulting in better patient comfort. • It is useful in manipulation across difficult curves and high bladder necks and median lobes. • The ability to flex the endoscope helps in complete visualization of the bladder easily. Dept Of Urology, KMC and GRH, Chennai 84
  • 85. Thank You Dept Of Urology, KMC and GRH, Chennai 85