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The Digital Health Chessboard:
                 Considerations for Start-ups
Healthcare Information & Media (“HIM”) Universe Defined

                                         Professional
                                                                                    HCIT Consulting Services
          DTP Advertising     Old CME                          New CME
                                                                            Clinical Collaboration
                      Prescribing Data                           Data Analytics
Physician Reference           Directories                                              Research Data
                                                             Practice Management
                                                                                        Management




                                               Spectrum
          Professional Journals                                     Smart Monitors
                            Digital Disease                 Lead-generation     Electronic Medical Records
                             Management                         Remote Monitoring

Content                      Information & Media Spectrum                                      Distribution


                                               Healthcare
                            Doctor Reviews
               Personal Health Magazines                      Tele-health/V-consults Appointment Scheduling
   Patient Education                                                           Electronic Health Records
                     Waiting Room Media
     DTC Advertising
                                                              Digital Health Management
                HC Social Networks
                                                                               Provider Collaboration
             Diagnostic Games/Awards                          UGC Publishing


                                            Consumer
                                              2
Elements of Sustainable Companies

   Clarity of Purpose: Summarize the company's business on the back of a business card.
   Large Markets: Address existing markets poised for rapid growth or change. A market on the
    path to a $1B potential allows for error and time for real margins to develop.
   Rich Customers: Target customers who will move fast and pay a premium for a unique offering.
   Focus: Customers will only buy a simple product with a singular value proposition.
   Pain Killers: Pick the one thing that is of burning importance to the customer then delight them
    with a compelling solution.
   Think Differently: Constantly challenge conventional wisdom. Take the contrarian route. Create
    novel solutions. Outwit the competition.
   Team DNA: A company’s DNA is set in the first 90 days. All team members are the smartest or
    most clever in their domain. "A" level founders attract an "A" level team.
   Agility: Stealth and speed will usually help beat-out large companies.
   Frugality: Focus spending on what's critical – headcount is a key metric. Spend only on the
    priorities and maximize profitability.
   Inferno: Start with only a little money. It forces discipline and focus. A huge market with
    customers yearning for a product developed by great engineers requires very little firepower.




                                               3
Raising Capital for Growth

              Do your homework upfront
Preparation      Know who your best investors are and at which stage they invest at, return
                  hurdles, etc.
                 Map out your business plan in as much detail as possible – be transparent
                 Identify all competitors – having no competition is not a good thing

              Approach the Investor Universe All at Once
                 Lock step discussions with investors is the quickest way to give away your
Value             negotiating leverage
                 Ask for as much money as you need to fund your entire plan (< 20% market
                  share), because the funding window may not be open in the future

              Ask for help – don’t go to Court without a Lawyer!
                 Try to find “Smart Money” – that can help scale a business
Partners         Incubators, venture investors initially and later on investment bankers
                 An Investment Banker’s role is to identify and communicate the underlying
                  value drivers in the business; bring awareness of the operating strategies of
                  each potential buyer; maintain assertive control of the auction process; have
                  hands-on management of due diligence; and enlist skillful negotiation
                 Strong advisors build venture credibility


                                        4
HIM Investments By Stage in Q1 2012

EARLY                          CORPORATE LIFECYCLE                               MATURE


Seed Deals                         Series A & B                               Series C & D

 # of Deals: 2                   # of Deals: 8                    # of Deals: 17
 Amount: $1.4M                   Amount: $75.5M                   Amount: $107.2M
 Typical Deal Size: <$1M         Typical Deal Size: $5M+          Typical Deal Size: $15M+



                   Early Stage Smart Money and Angels Sources
    http://rockhealth.com/
    http://www.healthboxaccelerator.com/
    http://www.blueprinthealth.org/
    http://www.startuphealth.com/
    http://www.remedysystems.com/
    http://angel.co/
    http://www.crunchbase.com/
    http://gust.com/funding-resource/california-healthcare-foundation/
    http://www.healthevolutionpartners.com/
    http://www.athenahealth.com/disruption/
                                         5
Methods for Valuing a Startup

 Cost-to-Duplicate
      •   Buy or build decision, ignores intangibles
 Market Multiple
 Discounted Cash Flow (“DCF”) – Market Potential
      •   <20% market share in 5-7 years
 Valuation by Stage

Est. Company Value          Stage of Development


$250,000 - $500,000         Has an exciting business idea or business plan


$500,000 - $1 million       Has a strong management team in place to execute on the plan


$1 million – $2 million     Has a final product or technology prototype


$2 million – $5 million     Has strategic alliances or partners, or signs of a customer base


$5 million and up           Has clear signs of revenue growth and obvious pathway to profitability


                                             6
Potential Buyer List: Investors in the HIM Space

                 Investors                              Recent HIM Investments                        Contact Information
Connecticut Innovations                 MyCare, Innovatient Solutions                         http://www.ctinnovations.com
Aberdare Ventures                       Jiff                                                  http://www.aberdare.com
Aeris Capital                           Jiff                                                  http://www.aeris-capital.com
BlueCross BlueShield Venture Partners   Change Healthcare                                     http://www.bcbsvp.com
Bluff Point Associates                  DocuTAP                                               http://bluffpt.com
Charter Life Sciences                   Health Fidelity                                       http://www.charterls.com
CHV Capital                             PerfectServe                                          http://chvcapital.com
Draper Triangle Ventures                OnShift                                               http://drapertriangle.com
Early Stage Partners                    OnShift                                               http://www.esplp.com
Easton Capital                          TigerText                                             http://www.eastoncapital.com
Emerald Stage2 Ventures                 Halfpenny Technologies                                http://www.s2vc.com
First Round Capital                     Truveris                                              http://www.firstround.com
Frontier Capital                        Healthx                                               http://www.frontiercapital.com
Galen Partners                          Sharecare                                             http://www.galen.com
Glengary                                OnShift                                               http://www.glengaryllc.com
HLM Venture Partners                    Silverlink Communications                             http://www.hlmvp.com
Insight Venture Partners                Kinnser Software                                      http://www.insightpartners.com
iRobot                                  InTouch Health                                        http://www.irobot.com
LORE Associates                         Halfpenny Technologies                                http://www.thresholdpartners.com
HLM Venture Partners                    MedVentive, RedBrick, AventuraHQ, Teladoc             http://www.hlmvp.com
Cardinal Partners                       Awarepoint Corporation, Teladoc, lifeIMAGE            http://www.cardinalpartners.com
Chrysalis Ventures                      Intervention Insights, meQuilibrium, MyHealthDIRECT   http://www.chrysalisventures.com
Founders Fund                           100Plus, Practice Fusion                              http://www.foundersfund.com
Innovation Endeavors                    HealthTap, PharmaSecure                               http://innovationendeavors.com
Kleiner Perkins Caufield & Byers        RedBrick, Teladoc, Awarepoint Corporation             http://www.kpcb.com
CHV Capital                             MedVentive                                            http://chvcapital.com
Versant Ventures                        Advanced ICU Care, RedBrick                           http://www.versantventures.com



                                                          7
Buyer Hot Buttons


                                          Barriers to Entry

                      Growth Rate &                               Market Size &
                         Outlook                                     Share

       Intellectual
                                                                                  Competition
        Property



 Audience Capture                             Value                                  Management
                                              Drivers
   Multi-Channel                                                                  Business Model
    Distribution                                                                     Maturity


             Geographic                                                    Potential for
              Markets                                                      Acquisitions

                                                           Customer
                             Brand Strength
                                                          Concentration




                                              8
Writing a Business Plan – Pitching Potential Investors
   Presentation: 15-20 slides with a lot of information in as few words as possible.
   Company Purpose: Define the company/business in a single declarative sentence.
   Problem: Describe the pain of the customer (or the customer’s customer). Outline how the
    customer addresses the issue today.
   Solution: Demonstrate your company’s value proposition to make the customer’s life better.
   Why Now
     • Set-up the historical evolution of your category.
     • Define recent trends that make your solution possible.
   Market Size: Calculate the size of market
     • Top down (e.g. analyst projections, externally reported)
     • Bottoms up (e.g. calculate users/usage/rev$)
   Competition: List competitors, competitive advantages
   Product
     • Product line-up (form factor, functionality, features, architecture, intellectual property)
     • Development growth/investment roadmap (keep market share under 20%)
   Business Model
     • Revenue model (unit economic analysis), pricing
     • Average account size and/or lifetime value, customer/pipeline list
     • Sales & distribution model
   Team: Founders, Management, Board of Directors, Board of Advisors
   Financials: P&L, balance sheet, cash flow, cap table, sources & uses

                                               9
Software Revenue Models

 Software as a service (SaaS) is a software application delivery model in
   which customers pay to access and use software functionality over a
   network through a hosted, web-native platform operated by the software
   vendor (either independently or through a third-party).




                                   10
The Dynamics of the Sales Process
                                                          Key Factors
                Valuation – Closing – Probability – Confidentiality – Business Disruption – Negotiating Leverage



     Negotiated Approach                                      Targeted Auction                                     Broad Auction
    A carefully selected group of buyers are           A limited group of highly qualified buyers are   Indications of interest are solicited from a broad
prioritized according to their acquisition interest      contacted and offered the opportunity to         spectrum of potential buyers with the goal of
   & ability, and are contacted one at a time                      evaluate the Company                       creating a highly competitive auction


Advantages                                            Advantages                                        Advantages
 Highest degree of confidentiality                    Promotes competition among a select              Creates maximum competition
 Best control over information                         group of prequalified buyers                     Asserts pressure on buyers to submit
 Seller can terminate process easily                  Confines information distribution to a            fully financed bids
                                                        relatively small group                           Maximizes likelihood that all viable
 Minimal possibility for information to
  leak outside small group                             Some flexibility to cancel the process            buyers will be contacted
                                                        without contaminating the market                 Most likely to achieve the full value of
 Least business disruption
                                                       Effective approach when there are                 the asset
 Leaves opportunity to conduct                         clearly identifiable buyers
  another transaction process at a later                                                                 Provides early insight on buyer
  date                                                 Allows for a faster time-schedule than            perspectives on value, structure and
                                                        a broad auction                                   issues


Concerns                                                                                                Concerns
 Lack of competition typically will not                                                                 Information is broadly distributed
  result in the highest value being                                                                      Can attract tire-kickers
  achieved
                                                                                                         More difficult to unwind the process;
 Negotiating position is weak                                                                            risk of contaminating the market
 Can take a long period of time                                                                         Significant interaction between
 Process lacks urgency                                                                                   greater number of buyers and the
                                                                                                          Company
                                                                                                         Two-step approach extends process

                                                                      11
Targeted Auction Process Overview

      Preparation                 Marketing                           Selling                    Closing

      2 – 4 weeks                 1 – 3 weeks                      4 – 6 weeks                4 – 5 weeks
     Initiation Phase        Qualification & Outreach           Demonstrate Value               Execution

 Review sequence and        Finalize prospective           Receive and analyze        Select winning bidder
  timing                      buyers list                     indications of interest    Facilitate confirmatory
 Complete internal due      Contact potential buyers       Select second round         due diligence
  diligence                   and negotiate CAs               participants               Negotiate and finalize
 Develop financial model    Distribute information         Conduct management          terms of Purchase
                              memorandums                     presentations               Agreement
 Gather market data
                             Assemble data room             Manage data room           Sign Agreement
 Refine positioning and
                                                              access
  investment                 Conduct listen-only                                        Closing
  considerations              management                     Facilitate buyer due
                              presentation                    diligence
 Compile buyers list
                             Prepare and rehearse           Manage interactions
                              management                      between management &
                              presentations                   buyers
                                                             Finalize draft Purchase
                                                              Agreement
                                                             Solicit final bids
                                                             Evaluate bids and/or
                                                              contract mark-ups


                                                       12
Advice to Potential Sellers

                          Determine key objectives to be achieved in a transaction, such as strategic and access-to-
    Understand             capital advantages
   Sale Objectives        Agree on importance of buyer characteristics like tax status, commitment to seller’s mission,
                           market position and reputation


  Manage Internal         Involve only critical staff required for due diligence, decision making; limit morale impact
  Communication           Minimize market disruption and buyer leverage with limited external communication


                          Compile internal information on financial, operational, legal, and market matters
   Perform Rigorous
                          Resolve any identified contractual or regulatory issues (e.g. assignability of contracts, etc.)
Internal Due Diligence
                          Define key value drivers and prepare supporting evidence

                          Take advantage of higher pricing environments and natural market cyclicality
  Time Market Entry
                          Negotiate from the strongest financial position through early market entry

   Move Quickly &         Avoid the potential of negative changes to organizational profile and local/national market
     Decisively           Hire a transaction advisor when ready to actively pursue options

                          Maintain leverage with a dynamic, systematic simultaneous buyer search; avoid sequential
                           exploration
  Involve Multiple        Run an iterative bidding process to identify highest bids, best terms and best strategic fits
  Potential Buyers        Negotiate comprehensive terms with multiple bidders to avoid re-trades
                          Explore breakup fees for bidders demanding exclusivity




                                                   13
Stay In Touch!


Lora Lindsey
Healthcare Information & Media

Passionate about connecting People and Ideas
in Health Information & Media (HIM)™




Email         LLindsey03@gsb.columbia.edu
Mobile        646.734.8375
Skype         Lora.Lindsey1
Twitter       @HIMBanker
LinkedIn      www.linkedin.com/pub/lora-lindsey/0/185/225
Pinterest     www.pinterest.com/HIMBanker
Crunchbase    www.crunchbase.com/

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Considerations for HIM Start-Ups 2012

  • 1. The Digital Health Chessboard: Considerations for Start-ups
  • 2. Healthcare Information & Media (“HIM”) Universe Defined Professional HCIT Consulting Services DTP Advertising Old CME New CME Clinical Collaboration Prescribing Data Data Analytics Physician Reference Directories Research Data Practice Management Management Spectrum Professional Journals Smart Monitors Digital Disease Lead-generation Electronic Medical Records Management Remote Monitoring Content Information & Media Spectrum Distribution Healthcare Doctor Reviews Personal Health Magazines Tele-health/V-consults Appointment Scheduling Patient Education Electronic Health Records Waiting Room Media DTC Advertising Digital Health Management HC Social Networks Provider Collaboration Diagnostic Games/Awards UGC Publishing Consumer 2
  • 3. Elements of Sustainable Companies  Clarity of Purpose: Summarize the company's business on the back of a business card.  Large Markets: Address existing markets poised for rapid growth or change. A market on the path to a $1B potential allows for error and time for real margins to develop.  Rich Customers: Target customers who will move fast and pay a premium for a unique offering.  Focus: Customers will only buy a simple product with a singular value proposition.  Pain Killers: Pick the one thing that is of burning importance to the customer then delight them with a compelling solution.  Think Differently: Constantly challenge conventional wisdom. Take the contrarian route. Create novel solutions. Outwit the competition.  Team DNA: A company’s DNA is set in the first 90 days. All team members are the smartest or most clever in their domain. "A" level founders attract an "A" level team.  Agility: Stealth and speed will usually help beat-out large companies.  Frugality: Focus spending on what's critical – headcount is a key metric. Spend only on the priorities and maximize profitability.  Inferno: Start with only a little money. It forces discipline and focus. A huge market with customers yearning for a product developed by great engineers requires very little firepower. 3
  • 4. Raising Capital for Growth Do your homework upfront Preparation  Know who your best investors are and at which stage they invest at, return hurdles, etc.  Map out your business plan in as much detail as possible – be transparent  Identify all competitors – having no competition is not a good thing Approach the Investor Universe All at Once  Lock step discussions with investors is the quickest way to give away your Value negotiating leverage  Ask for as much money as you need to fund your entire plan (< 20% market share), because the funding window may not be open in the future Ask for help – don’t go to Court without a Lawyer!  Try to find “Smart Money” – that can help scale a business Partners  Incubators, venture investors initially and later on investment bankers  An Investment Banker’s role is to identify and communicate the underlying value drivers in the business; bring awareness of the operating strategies of each potential buyer; maintain assertive control of the auction process; have hands-on management of due diligence; and enlist skillful negotiation  Strong advisors build venture credibility 4
  • 5. HIM Investments By Stage in Q1 2012 EARLY CORPORATE LIFECYCLE MATURE Seed Deals Series A & B Series C & D  # of Deals: 2  # of Deals: 8  # of Deals: 17  Amount: $1.4M  Amount: $75.5M  Amount: $107.2M  Typical Deal Size: <$1M  Typical Deal Size: $5M+  Typical Deal Size: $15M+ Early Stage Smart Money and Angels Sources  http://rockhealth.com/  http://www.healthboxaccelerator.com/  http://www.blueprinthealth.org/  http://www.startuphealth.com/  http://www.remedysystems.com/  http://angel.co/  http://www.crunchbase.com/  http://gust.com/funding-resource/california-healthcare-foundation/  http://www.healthevolutionpartners.com/  http://www.athenahealth.com/disruption/ 5
  • 6. Methods for Valuing a Startup  Cost-to-Duplicate • Buy or build decision, ignores intangibles  Market Multiple  Discounted Cash Flow (“DCF”) – Market Potential • <20% market share in 5-7 years  Valuation by Stage Est. Company Value Stage of Development $250,000 - $500,000 Has an exciting business idea or business plan $500,000 - $1 million Has a strong management team in place to execute on the plan $1 million – $2 million Has a final product or technology prototype $2 million – $5 million Has strategic alliances or partners, or signs of a customer base $5 million and up Has clear signs of revenue growth and obvious pathway to profitability 6
  • 7. Potential Buyer List: Investors in the HIM Space Investors Recent HIM Investments Contact Information Connecticut Innovations MyCare, Innovatient Solutions http://www.ctinnovations.com Aberdare Ventures Jiff http://www.aberdare.com Aeris Capital Jiff http://www.aeris-capital.com BlueCross BlueShield Venture Partners Change Healthcare http://www.bcbsvp.com Bluff Point Associates DocuTAP http://bluffpt.com Charter Life Sciences Health Fidelity http://www.charterls.com CHV Capital PerfectServe http://chvcapital.com Draper Triangle Ventures OnShift http://drapertriangle.com Early Stage Partners OnShift http://www.esplp.com Easton Capital TigerText http://www.eastoncapital.com Emerald Stage2 Ventures Halfpenny Technologies http://www.s2vc.com First Round Capital Truveris http://www.firstround.com Frontier Capital Healthx http://www.frontiercapital.com Galen Partners Sharecare http://www.galen.com Glengary OnShift http://www.glengaryllc.com HLM Venture Partners Silverlink Communications http://www.hlmvp.com Insight Venture Partners Kinnser Software http://www.insightpartners.com iRobot InTouch Health http://www.irobot.com LORE Associates Halfpenny Technologies http://www.thresholdpartners.com HLM Venture Partners MedVentive, RedBrick, AventuraHQ, Teladoc http://www.hlmvp.com Cardinal Partners Awarepoint Corporation, Teladoc, lifeIMAGE http://www.cardinalpartners.com Chrysalis Ventures Intervention Insights, meQuilibrium, MyHealthDIRECT http://www.chrysalisventures.com Founders Fund 100Plus, Practice Fusion http://www.foundersfund.com Innovation Endeavors HealthTap, PharmaSecure http://innovationendeavors.com Kleiner Perkins Caufield & Byers RedBrick, Teladoc, Awarepoint Corporation http://www.kpcb.com CHV Capital MedVentive http://chvcapital.com Versant Ventures Advanced ICU Care, RedBrick http://www.versantventures.com 7
  • 8. Buyer Hot Buttons Barriers to Entry Growth Rate & Market Size & Outlook Share Intellectual Competition Property Audience Capture Value Management Drivers Multi-Channel Business Model Distribution Maturity Geographic Potential for Markets Acquisitions Customer Brand Strength Concentration 8
  • 9. Writing a Business Plan – Pitching Potential Investors  Presentation: 15-20 slides with a lot of information in as few words as possible.  Company Purpose: Define the company/business in a single declarative sentence.  Problem: Describe the pain of the customer (or the customer’s customer). Outline how the customer addresses the issue today.  Solution: Demonstrate your company’s value proposition to make the customer’s life better.  Why Now • Set-up the historical evolution of your category. • Define recent trends that make your solution possible.  Market Size: Calculate the size of market • Top down (e.g. analyst projections, externally reported) • Bottoms up (e.g. calculate users/usage/rev$)  Competition: List competitors, competitive advantages  Product • Product line-up (form factor, functionality, features, architecture, intellectual property) • Development growth/investment roadmap (keep market share under 20%)  Business Model • Revenue model (unit economic analysis), pricing • Average account size and/or lifetime value, customer/pipeline list • Sales & distribution model  Team: Founders, Management, Board of Directors, Board of Advisors  Financials: P&L, balance sheet, cash flow, cap table, sources & uses 9
  • 10. Software Revenue Models  Software as a service (SaaS) is a software application delivery model in which customers pay to access and use software functionality over a network through a hosted, web-native platform operated by the software vendor (either independently or through a third-party). 10
  • 11. The Dynamics of the Sales Process Key Factors Valuation – Closing – Probability – Confidentiality – Business Disruption – Negotiating Leverage Negotiated Approach Targeted Auction Broad Auction A carefully selected group of buyers are A limited group of highly qualified buyers are Indications of interest are solicited from a broad prioritized according to their acquisition interest contacted and offered the opportunity to spectrum of potential buyers with the goal of & ability, and are contacted one at a time evaluate the Company creating a highly competitive auction Advantages Advantages Advantages  Highest degree of confidentiality  Promotes competition among a select  Creates maximum competition  Best control over information group of prequalified buyers  Asserts pressure on buyers to submit  Seller can terminate process easily  Confines information distribution to a fully financed bids relatively small group  Maximizes likelihood that all viable  Minimal possibility for information to leak outside small group  Some flexibility to cancel the process buyers will be contacted without contaminating the market  Most likely to achieve the full value of  Least business disruption  Effective approach when there are the asset  Leaves opportunity to conduct clearly identifiable buyers another transaction process at a later  Provides early insight on buyer date  Allows for a faster time-schedule than perspectives on value, structure and a broad auction issues Concerns Concerns  Lack of competition typically will not  Information is broadly distributed result in the highest value being  Can attract tire-kickers achieved  More difficult to unwind the process;  Negotiating position is weak risk of contaminating the market  Can take a long period of time  Significant interaction between  Process lacks urgency greater number of buyers and the Company  Two-step approach extends process 11
  • 12. Targeted Auction Process Overview Preparation Marketing Selling Closing 2 – 4 weeks 1 – 3 weeks 4 – 6 weeks 4 – 5 weeks Initiation Phase Qualification & Outreach Demonstrate Value Execution  Review sequence and  Finalize prospective  Receive and analyze  Select winning bidder timing buyers list indications of interest  Facilitate confirmatory  Complete internal due  Contact potential buyers  Select second round due diligence diligence and negotiate CAs participants  Negotiate and finalize  Develop financial model  Distribute information  Conduct management terms of Purchase memorandums presentations Agreement  Gather market data  Assemble data room  Manage data room  Sign Agreement  Refine positioning and access investment  Conduct listen-only  Closing considerations management  Facilitate buyer due presentation diligence  Compile buyers list  Prepare and rehearse  Manage interactions management between management & presentations buyers  Finalize draft Purchase Agreement  Solicit final bids  Evaluate bids and/or contract mark-ups 12
  • 13. Advice to Potential Sellers  Determine key objectives to be achieved in a transaction, such as strategic and access-to- Understand capital advantages Sale Objectives  Agree on importance of buyer characteristics like tax status, commitment to seller’s mission, market position and reputation Manage Internal  Involve only critical staff required for due diligence, decision making; limit morale impact Communication  Minimize market disruption and buyer leverage with limited external communication  Compile internal information on financial, operational, legal, and market matters Perform Rigorous  Resolve any identified contractual or regulatory issues (e.g. assignability of contracts, etc.) Internal Due Diligence  Define key value drivers and prepare supporting evidence  Take advantage of higher pricing environments and natural market cyclicality Time Market Entry  Negotiate from the strongest financial position through early market entry Move Quickly &  Avoid the potential of negative changes to organizational profile and local/national market Decisively  Hire a transaction advisor when ready to actively pursue options  Maintain leverage with a dynamic, systematic simultaneous buyer search; avoid sequential exploration Involve Multiple  Run an iterative bidding process to identify highest bids, best terms and best strategic fits Potential Buyers  Negotiate comprehensive terms with multiple bidders to avoid re-trades  Explore breakup fees for bidders demanding exclusivity 13
  • 14. Stay In Touch! Lora Lindsey Healthcare Information & Media Passionate about connecting People and Ideas in Health Information & Media (HIM)™ Email LLindsey03@gsb.columbia.edu Mobile 646.734.8375 Skype Lora.Lindsey1 Twitter @HIMBanker LinkedIn www.linkedin.com/pub/lora-lindsey/0/185/225 Pinterest www.pinterest.com/HIMBanker Crunchbase www.crunchbase.com/