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Dietary Management
pinal Cord Injury
Colonel Hana K. Mudabber
Head of Clinical Nutrition Department
S of
Coordination of Care
 Optimal care of SCI patient requires a
multidisciplinary approach in all aspects
of patient care including nutrition
SCI : Interdisciplinary Team
Others
Role of the Clinical Dietitian
 Participate in the interdisciplinary team by
providing care for Neurotrauma patients in all
aspects of patient care:
1. Acute phase
2. Rehabilitation phase
3. Community setting (After Discharge)
Nutrition Management
in the Acute Phase
Nutritional needs change frequently after SCI
Stress response
Sepsis
Fever
Infection
Surgery
Nutritional assessments need to be frequent,
with ongoing diet alterations made to keep up
with the patients' changing needs
Caloric and protein needs
in the acute phase
Management of Hypermetabolism
Algorithm content developed by John Anderson, PhD, and Sanford C. Garner, PhD, 2000. Updated by Maion F. Winkler and Ainsley Malone, 2002.
SCI: Nutrition Assessment in the
Acute Care Setting
Nutrition assessment should be conducted within
the first 48 hours post-injury to determine
Nutrient needs
Provide nutrition support recommendations
Early nutrition support is associated with improved patient
outcomes
Identify conditions that may predispose the patient to
nutrition-related complications
SCIInflammation
Malnutrition
Loss of muscle
mass
Loss of activity
Acute Illness & Nutritional Status
After injury: weight loss due to loss of muscle
or lean body tissue
Complications with Loss
of Lean Body Mass
% Loss Total LBM Complications Associated Mortality
%
10 Decreased immunity,
Increased infections
10
20 Decreased healing,
weakness, infection
30
30 Too weak to sit,
pressure ulcers,
pneumonia, no
healing
50
40 Death, usually from
pneumonia
100
What is the best route of delivery:
Enteral vs. Parenteral
Enteral Nutrition (EN):
Enteral nutrition is a treatment
option when oral nutrition is
unsafe
due to aspiration risk
or when the
patient can no
longer meet nutritional needs
with an oral diet.
Enteral Nutritional Support
Continuous EN
Better tolerated than
bolus/intermittent EN in ICU
setting
Limit interruptions!
Unnecessary for certain
procedures—NPO at midnight
should not be automatic
Low rate of gastric residuals
Benefits - EN
Supports gut integrity
Modulate stress and immune response
Lower risk of infection than Parenteral
Nutrition (PN)
Reduction in hospital LOS
 catabolism
Improve the nutritional status (meet protein,
energy and micronutrient requirements)
 Infection
Lower cost
Quicker return of cognitive function
(Taylor, et. al)
Risks of EN
Feeding when gut perfusion poor can lead to
gut ischemia
Feeding intolerance in critical illness
May not reach nutritional goals as quickly as
PN
Parenteral Nutrition
Benefits
Fewer interruptions in feeding
Nutrition goals reached quickly
Least desirable
Increased risk of infection
Increased cost
Increased risk of mortality
SCI: Energy Needs in the Acute Phase
Indirect calorimetry is considered to be the 'gold
standard' and the only accurate and clinically feasible
method of measuring energy expenditure in critically ill
hypermetabolic patients
It is called “indirect” because the caloric burn rate is
calculated from a measurement of oxygen uptake.
Used in both mechanically ventilated
and spontaneously breathing patients
(ventilated patients most accurate)
Equipment is expensive and not readily
available in the medical facilities
SCI: Assessment: Energy Needs in the
Acute Phase using Predictive Equations
If Indirect Calorimetry is not available, the
clinical dietitian may estimate energy
needs with the Harris-Benedict formula
using admission weight
an injury factor of 1.2
an activity factor of 1.1
Harris-Benedict Formula
Basal Energy Expenditure
Male: BEE = 66.67 + 13.75W + 5H - 6.76A
Female: BEE = 665.1 + 9.56W +1.85H -4.68A
H= height in centimeters
W= weight in kg
 A= age in years.
SCI: Calculations of Energy Needs
Harris-Benedict Formula
Energy Needs = [BEE]) X (activity factor) X (injury factor)
an injury factor of 1.2
an activity factor of 1.1
SCI: Protein Needs in Acute Phase
2.0 g/kg of ideal body weight/day to minimize -ve
nitrogen balance that occurs during the acute
phase
Status Estimated Requirements
Normal (RDA) 0.8-1.0 g/kg/day
Moderately stress 1.0-2.0 g/kg/day
Severely stressed 2.0-3.0 g/kg/day
Blackburn's General Guide for Protein Needs Based on Stress level
SCI: Monitoring and Evaluation of
Protein Intake in Acute Care Setting:
Overfeeding
0 – 4 weeks post-injury : the clinical dietitian
should monitor the patient's protein intake to
ensure that the patient does not consume more
than 2.0g/kg of body weight/day to achieve +ve
nitrogen balance without any excessive nutrition
support that may result in overload and
metabolic complications
Nutrition Management
in the Rehabilitation Setting
SCI: Goals of Nutrition Assessment in
the Rehabilitation Setting
Implementing an individualized
therapeutic nutrition plan for the patient
Improving transition into the community
setting
SCI: Energy Needs
Patients with SCI have reduced metabolic activity due to
denervated muscle
Actual energy needs are at least 10% below predicted
needs
22.7 kcal/ kg body weight for patients with quadriplegia
27.9 kcal/ kg for those with paraplegia
Example:
Patient weight 70 kg x 22.7 ≅ 1600 kcal/day energy needs for
patient with quadriplegia
SCI: Protein Needs
in the Rehabilitation Setting
(0.8 to 1.0) g/kg/day for maintenance of
protein status in the absence of
pressure ulcers or infection
Example:
Patient weight 70 kg x1 = 70 /day protein
needs for patient with SCI
Community Setting
After Discharge
SCI: Nutrition Assessment
in the Community Setting
Should be conducted as part of the annual
medical exam
Developing and implementing an individualized
therapeutic nutrition plan necessary to identify
secondary SCI conditions related to nutrition
Secondary SCI Conditions
Related to Nutrition
1. Metabolic Syndrome
2. Overweight and Obesity
3. Lipid Abnormalities
4. Pressure Ulcers
5. Bowel Problems
6. Urinary Tract Infections
1. Metabolic Syndrome
 Metabolic Syndrome is not a single disease
but a group of health problems that is
believed to arise due to a combination of
1. Genetic factors
2. Lifestyle factors including overeating
3. Lack of physical activity
Symptoms of Metabolic Syndrome
1. Waist Circumference greater than
102 cm for men and 88 cm for
women (in SCI population it is likely
a different estimation)
2. Triglyceride level ≥150 mg/dL
3. HDL < 40 mg/dL in men
and <50 mg/dL in women
4. Blood pressure > 130/85 mmHg
5. Blood sugar > 110 mg/dL
Dietary Recommendations to Prevent
Metabolic Syndrome & Overweight/Obesity
Limiting Fat Intake
Choosing fat free or low fat dairy products
Choosing lean meats and skinless poultry and fish
Reducing Saturated Fat and Trans Fat
These are the fats that are solid at room temp
Animal fats
Shortening
Palm and coconut oil
Dietary Recommendations to Prevent
Metabolic Syndrome & Overweight/Obesity
Eating less cholesterol
Cholesterol is in foods from animal origin
reducing the amount of saturated (animal fat)
Increasing fruit and vegetable intake
Limiting empty calories
Choosing water or diet beverages over regular soda &
reducing the amount of sweets & sugars & alcohol
For the general population overweight and
obesity can be categorized by using BMI
BMI<18.5- Underweight
BMI 18.5-24.9- Normal Weight
BMI 25-29.9- Overweight
BMI 30-39.9- Obese
BMI >40- Extreme Obese
2. Overweight and Obesity
SCI: Assessment of Body Composition: BMI
and skinfold measurements
The clinical dietitian should not use
the following to measure
body composition in
persons with SCI:
 body mass index (BMI)
Skinfold measurements
These methods may not provide
reliable results since they
were developed based
on able-
bodied persons.
SCI: Estimation of Ideal Body Weight
Quadraplegia or (Tetraplagia):
Reduction of 10% to 15% (7-9) kg
lower than table weight
Paraplegia:
Reduction of 5% to 10%
(4.5-7) kg lower than table weight
Estimation of Ideal Body Weight
The clinical dietitian should estimate ideal
body weight for persons with SCI by
adjusting the Metropolitan Life Insurance
tables for individuals of equivalent height
and weight
Height (m)
Frame Size
Medium Large
Para Tetra Para Tetra
1.57 49 46.5 54.5 52
1.60 51 49 57 55
1.62 54.5 52 60 58
1.65 57 55 63.5 61
1.67 60 58 66 64
1.70 62 60 69 67
1.72 65 63 72 69
1.75 68.5 66 75 73
1.77 75 68 78.5 76
1.80 73.5 71 81 78.5
1.83 76 74 85 82
1.86 79 77 87 85
1.88 81 79 90 88
1.91 84 82 93.5 91
1.93 86.5 85 96 94
1.96 90 88 99 97
1.98 92 90 102 99.5
S
C
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M
E
N
W
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G
H
T
T
A
B
L
E
S
S
C
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W
O
M
E
N
W
E
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H
T
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A
B
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S
Height (m)
Frame Size
Medium Large
Para Tetra Para Tetra
1.47 36 34 40 38
1.5 38.5 36 43.5 41
1.52 41 39 45 43
1.55 43.5 41 48.5 46
1.57 45 43 46 48
1.60 47 45 53.5 51
1.62 50 48 55.5 53
1.65 52 49 57.5 55
1.67 54.5 52 60.5 58
1.70 56 54 63 61
1.72 59.5 57 65 63
1.75 61 59 68 66
1.77 63.5 61 70 68
1.78 66 64 73.5 71
1.83 68.5 66 75 73
SCI: Assessment of Body Composition:
BIA and DEXA
 Assessment of body composition for medically
stable SCI patients by using
Bio-electric Impedance Analysis (BIA)
Dual-Energy X-Ray Absorptiometry (DEXA)
Persons with SCI have significantly higher fat
mass and lower lean mass than persons without
SCI
(BIA)
Bioelectric impedance Analysis
(DEXA)
Dual-Energy X-Ray Absorptiometry
What’s the difference between weight &
body fat in terms of health risks?
Weight measurement alone cannot accurately
determine a person’s body fat % and the
resulting health risks
 New evidence indicates that fat loss, not weight
loss can extend lifespan
Level of Body Fat % for General Health
Adult Male Adult Female
Age Excellent Good Average Poor Age Excellent Good Average Poor
19-24 10.8% 14.9% 19.0% 23.3% 19-24 18.9% 22.1% 25.0% 29.6%
25-29 12.8% 16.5% 20.3% 24.4% 25-29 18.9% 22.0% 25.4% 29.8%
30-34 14.5% 18.0% 21.5% 25.2% 30-34 19.7% 22.7% 26.4% 30.5%
35-39 16.1% 19.4% 22.6% 26.1% 35-39 21.0% 24.0% 27.7% 31.5%
40-44 17.5% 20.5% 23.6% 26.9% 40-44 22.6% 25.6% 29.3% 32.8%
45-49 18.6% 21.5% 24.5% 27.6% 45-49 24.3% 27.3% 30.9% 34.1%
50-54 19.4% 22.7% 25.6% 28.7% 50-54 26.6% 29.7% 33.1% 36.2%
54-59 20.2% 23.2% 26.2% 29.3% 54-59 27.4% 30.7% 34.0% 37.3%
60 20.3% 23.5% 26.7% 29.8% 60 27.6% 31.0% 34.4% 38.0%
Example
Patient: 30 years old male
BMI= 17.9 Underweight
Average % fat assessed: 28.2%
This would make this patient obese because in
this age group the amount of fat that is
considered acceptable is 18-25%, making this
seemingly underweight patient obese
SCI: Risks Associated Overweight & Obesity
The SCI patients is at a higher risk of associated
comorbidities
Diabetes
Metabolic syndrome
Cardiovascular disease
Lower levels of spontaneous physical activity and a
lower thermic effect of food result in decreased energy
expenditure and energy needs.
What is the Thermic Effect of Food?
It is a reference to the increase in metabolic rate (i.e. the
rate at which your body burns calories) that occurs after
ingestion of food.
Energy expenditure (i.e. calories) to digest, absorb, and
store the nutrients; accounts for 5 to 10 % of the energy
content of the food ingested.
Example
500 calorie meal, 50 calories (or 10%) would be expected
to be burned due to the thermic effect of food, a net
calorie consumption of 500 - 50 = 450 calories.
Influence of Body Composition on the
Thermic Effect of Food
Lean people have a thermic effect of food
2 to 3 X greater than obese or people with
higher body fat %, during rest, after
exercise, and during exercise.
Segal KR, Gutin B, Albu J, Pi-Sunyer FX. Thermic effects of food and exercise in lean and obese men of similar lean
body mass. Am J Physiol. 1987 Jan;252(1 Pt 1):E110-7.
SCI: Wheel Chairs & Energy Needs
Compared to ultralight wheelchairs and pushrim-
activated, power-assisted wheelchairs; The use of
a manual standard wheelchair increases:
Energy needs
 heart rate
Oxygen consumption and ventilation, especially as
speed and resistance levels increase
SCI: Nutrition Education
Regarding Physical Activity
physical activity should be encouraged as part
of a comprehensive weight management
program for overweight or obese SCI patients
Physical Activity for SCI Patients
Swimming
Electrical stimulation exercise
Body weight supported
Treadmill training
3. Lipid Abnormalities
SCI patients are at higher risk of cardiovascular
conditions.
Cardioprotective diet should be
provided if total cholesterol
levels > 200mg/dL
SCI: Factors Related to Lipid Abnormalities
Age
Ethnicity
Gender
Time since injury
Level of injury
Activity level
Dietary habits
Smoking behavior
Alcohol intake
Overweight or obese status
ModifiableNon-Modifiable
SCI: Nutrition Screening for Lipid
Abnormalities
Screening for lipid abnormalities is recommended for all
persons with SCI in order to reduce morbidity and
mortality.
 Up to 30% deaths from CHD
due to an unhealthy diet
 36% due to inactivity
NHF (2006)
 Up to 30% deaths from CHD
due to an unhealthy diet
 36% due to inactivity
NHF (2006)
4. Pressure Ulcers
Patients who are at the
greatest risk of developing
pressure ulcers
Nonambulatory
Compromised nutritional
status
Pressure ulcers are
secondary to the decrease
in oxygen supplied to at-
risk areas (eg, coccyx,
elbows, heels)
Modifiable
SCI: Nutrition Prescription for SCI
Persons with Pressure Ulcers
A nutrition prescription should be formulated as part of
the nutrition intervention for persons with (SCI) and
pressure ulcers
Energy
Protein
Fluid
Micronutrient requirements
Additional energy and protein is needed for optimal
healing of pressure ulcers
Fluid and micronutrient needs will vary depending on the
person's status.
Nutritional Assessment
The Clinical Dietitian should assess for:
 Anthropometrics
Skin integrity
Dietary intake
Lifestyle factors
Biochemical indices
SCI: Biochemical Parameters Associated
with Prevention of Pressure Ulcers
laboratory indices associated with the risk of
pressure ulcers
albumin, Prealbumin, Zinc, vitamin A and vitamin C
Biochemical parameters as close to normal as
possible or within the normal range are
associated with reduced risk of pressure ulcers.
Serum Albumin
Hypoalbuminemia, has been associated with the
development and progression of pressure ulcers.
 Nutritional intervention needs to include adequate
protein and adequate calories to spare protein for
wound healing.
The goal is a serum albumin of greater than 3.5 g/dL
The amount of protein and number of calories need
to increase as the stage of the ulcer increases
SCI: Assessment: Energy Needs with
Pressure Ulcers
SCI patients with pressure ulcers have higher
energy needs
Additional energy is needed for optimal healing
30 – 40 kcal/kg of body weight/day
Harris-Benedict x Stress Factor
1.2 for stage II ulcer
1.5 for stage III and IV ulcers
SCI: Assessment: Protein Needs with
Pressure Ulcers
The clinical dietitian should calculate
protein needs as follows:
(1.2 - 1.5)g of protein/kg body weight/day
(Stage II pressure ulcers)
(1.5 - 2.0)g of protein/kg body weight/day
(Stage III and IV pressure ulcers).
Arginine
Dietary supplementation with arginine has been shown
to enhance protein metabolism, helping to decrease
muscle loss, and collagen synthesis, which helps to
increase the strength of the wound
Increased protein demand for normally nonessential amino
acids, becomes essential (conditionally essential)
Increases IGF-1 (Insulin Like Growth Factor) level
hormone that promotes wound healing
Studies suggest +ve outcomes in post-op surgical
wounds.
L-Arginine is also effective in healing chronic ulcers in
people with diabetes (ultimately helping to reduce leg
amputations)
When and How to Use Arginine
Should NOT be first line of defense
Consider for non-healing wounds after calorie
and protein needs met
Therapeutic dose to promote healing is ~9
grams/day
Side effects
L-Arginine supplementation can cause diarrhea.
Gradual increase of daily dose may help
tolerance.
Glutamine
Functions
Regulates amino acid homeostasis
Preferred energy source for rapidly
multiplying cells of intestinal mucosa and
immune system
May stabilize the intestinal barrier, reducing
risk of bacterial translocation and systemic
inflammatory response [Neu 2002]
Clinical trials of supplementation suggest benefit
but remain inconclusive.
How and When to Use Glutamine
This is NOT first line of defense
Indications are for patients with GI
impairment and Immune deficiencies
Provide 15-30g/day or 0.57 gm/kg wt
ß-Hydroxy-ß-methyl-butyrate (HMB)
Substance derived from breakdown of amino
acid leucine
Function
Anti-catablic agent
Used for reduction of muscle tissue
breakdown
Lack of clinical trials available
Some Products are marketed for wound healing
Contains 7 gm arginine, 7 gm glutamine, 1.5
g HMB per packet
SCI: Fluid Needs with Pressure Ulcers
The clinical dietitian should assess hydration
status to determine fluid needs.
evaluation of parameters such as input and output
urine color
skin turgor
BUN
serum sodium
Fluid Needs with Pressure Ulcers
Normal requirement: (30 – 40)ml/kg
Minimum of 1 ml/kcal/day
(10 – 15) ml per kg additional fluids
may be required with the use of air
fluidized beds set at a high temp.
(more than 31º to 34ºC
Fluid loss also includes evaporation
from open wounds, wound drainage
and fever
SCI: Nutrition Support & Pressure Ulcers
Implementing aggressive nutrition support
measures for SCI patients at risk of
pressure ulcer development may include
(Enteral and Parenteral Nutrition)
Improved nutrition intake, body weight and
biochemical parameters are associated with
reduced risk of pressure ulcer development
SCI: Micronutrients & Wound Healing
Daily vitamin and mineral supplement
should not be more than 100% of the
RDA.
 When supplementing greater than the Tolerable
Upper Intake Level (UL); the dietitian should re-
evaluate the need for micronutrient
supplementation every 7 to 10 days.
Vitamin A
Stimulates differentiation in fibroblasts and
collagen synthesis to quicken healing
Vitamin A deficiency results in impaired wound
healing and alteration in immune function that
may increase wound infections.
Recommendations for amount of Vitamin A is
(10,000 IU to 50,000 IU /day)
10,000 IU IV for moderate-severely injured patients
or malnourished patients for a limit of 10 days.
Vitamin A & Steroids
For patients receiving steroids, 10,000 IU
to 15,000 IU for one week has been
recommended to counteract the anti-
inflammatory effects of steroids
Steroids adversely affect all phases of
wound healing and increase risk of
infection[Ross 2002]
Vitamin A supplementation should be
implemented cautiously because of
potential toxicity
Vitamin C
Necessary for collagen synthesis
Enhances immune function
 Depressed levels found in elderly, smokers,
and certain cancers [Ross 2002]
Vitamin C deficiency has been associated with
delayed wound healing
High doses of Vitamin C for healing chronic
wounds is recommended
(100 to 200)mg/day of Vitamin C for Stage I and II
pressure ulcers
(1,000 to 2,000) mg/day of Vitamin C for Stage III
and IV pressure ulcers
Zinc
Zinc deficiency is associated with delayed wound healing
due to a decrease in collagen protein synthesis and
impaired immune competence.
(50mg elemental Zinc) twice/day is recommended as a
standard adult oral replacement (minimal daily
requirements is 15 mg/d)
High-dose supplementation of zinc
should be limited to (2-3) weeks
Dosage should be individualized
according to zinc status and metabolic
demands.
Iron
Anemia assessed by hemoglobin and
hematocrit levels
If low hemoglobin concentration is due
to iron deficiency anemia, it may be a
factor in tissue hypoxia and impaired
wound healing.
Supplementation should be provided
as indicated to correct iron deficiency
anemia.
There are 58 studies about curcumin &
wound healing in the PubMed until this
date 30/6/2011
Recent Researches
A search of PubMed on the
internet reveals some 58
scientific and technical
papers referenced to
curcumin and wound healing
Curcumin & Wound-healing
Dermal wound healing processes with curcumin incorporated collagen films
Gopinath D.etal Biomaterials. 2004 May;25(10):1911-7
Protective effects of curcumin against oxidative damage on skin cells in
vitro: its implication for wound healing
Phan TTetal J Trauma. 2001 Nov;51(5):927-31
Enhancement of wound healing by curcumin in animals
Sidhu G Setal , Wound Repair Regen. 1998 Mar-Apr;6(2):167-77
Inhibitory effect o fcurcuminon PMA-induced increase in ODC m RNA in
mouse epidermis Lu
YP…Conney AH, Carcinogenesis. 1993 Feb;14(2):293-7
Inhibitory effect of dietary curcuminon skin carcinogenesisin mice
LimtrakulP., CancerLett. 1997 Jun 24;116(2):197-203
Turmeric and curcuminas topical agents in cancer therapy
KuttanR.,Tumori. 1987 Feb 28;73(1):29-31
5. Neurogenic Bowel
The Clinical Dietitian should prescribe for SCI
patient with neurogenic bowel an initial fiber
intake of 15g/day, with gradual increases
up to 30g/day of fiber, as tolerated from a
variety of sources.
Excessive fiber may result in unacceptable
Flatulence
Significant increase in stool volume
Painful abdominal distension
5. Neurogenic Bowel
Fiber intake > 20g/day may be
associated with undesirable
prolonged intestinal transit times
resulting in excessive fluid
reabsorption and the formation
of hardened stools
Transit TimeTransit Time
Constipation
Juices, especially those high in sorbitol,
can help relieve constipation.
Juices that are Good for Chronic
Constipation
Sorbitol is a natural fruit sugar that is
poorly absorbed by the intestines, so
it stays in the intestinal tract and
makes the stools more liquid
Prune juice
Prune juice contains 6.1 g of
sorbitol /100-g serving
Prune juice and other prune
products have long been used to
relieve constipation due to their
laxative effect
An added benefit of prune juice
over many other fruit juices is that
it does not cause a spike in blood
sugar, which can be dangerous for
diabetics.
Baylor College of Medicine
Pear Juice
One 8-oz glass of pear juice
can contain as much as 7 g of
sorbitol.
As few as 10 g of sorbitol can
cause diarrhea in children
(it is best to offer a child
only a small amount to assist
in chronic constipation relief)
Baylor College of Medicine
Apple Juice
Apple juice is naturally high in
sorbitol
It is a mild juice that can cause
gas in some individuals
it is often one of the first
juices given to babies who have constipation
It is suggested to give babies 2 oz of apple juice
twice per day for constipation
Constipation
 Foods (such as dairy products, white potatoes,
white bread and bananas) can contribute to
constipation
 Foods (such as excess amounts of fruit, caffeine,
or spicy foods and warm fluids with lemon juice)
may soften the stool or cause diarrhea
Constipation
 Drinking water and eating high-fiber foods such as
fruits, vegetables, whole grains and legumes may
help to soften and make the stool bulkier, which
stimulates movement of the bowel
 Peristalsis can be stimulated with vegetables, fruits
(especially dried fruits)
 Dried fruits are the ideal substitute for candies
SCI: Fluid & Neurogenic Bowel:
Estimating Fluid Needs to Promote Optimal Stool Consistency
1 ml fluid/kcal estimated energy needs + 500 ml
Example
 1500 fluid/kcal estimated energy needs+ 500 ml= 2000
ml fluid Needs/day
30-40ml/kg body weight + 500 ml
Example
 40 x 55 kg body weight + 500 ml = 2700 ml fluid
needs/day
SCI: Fluid & Neurogenic Bowel:
6. Urinary Tract Infections
The Clinical Dietitian may recommend
that cranberry juice be included in the
diet to reduce urinary tract infections
Consumption of one cup (250ml)
cranberry juice, 3 times/day, may be
associated with a reduced urinary tract
biofilm load
Cranberry juice contains hippuric acid
and another substances that seems to
prevent adherence of bacteria to
urinary tract epithelial
SCI: Cranberry Extract Supplements
The Clinical Dietitian should not
recommend cranberry extract
supplements to promote urologic
health (prevention of urinary tract
infections, urologic stones, etc.) with
SCI patients
 Cranberry extract supplements,
ingested in tablet or capsule form, are
not effective in prolonging the UTI-free
period or decreasing bacteriuria or
WBC count in persons with SCI
patients
Food
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HANA SCI

  • 1. Dietary Management pinal Cord Injury Colonel Hana K. Mudabber Head of Clinical Nutrition Department S of
  • 2. Coordination of Care  Optimal care of SCI patient requires a multidisciplinary approach in all aspects of patient care including nutrition
  • 4. Role of the Clinical Dietitian  Participate in the interdisciplinary team by providing care for Neurotrauma patients in all aspects of patient care: 1. Acute phase 2. Rehabilitation phase 3. Community setting (After Discharge)
  • 6. Nutritional needs change frequently after SCI Stress response Sepsis Fever Infection Surgery Nutritional assessments need to be frequent, with ongoing diet alterations made to keep up with the patients' changing needs Caloric and protein needs in the acute phase
  • 7. Management of Hypermetabolism Algorithm content developed by John Anderson, PhD, and Sanford C. Garner, PhD, 2000. Updated by Maion F. Winkler and Ainsley Malone, 2002.
  • 8. SCI: Nutrition Assessment in the Acute Care Setting Nutrition assessment should be conducted within the first 48 hours post-injury to determine Nutrient needs Provide nutrition support recommendations Early nutrition support is associated with improved patient outcomes Identify conditions that may predispose the patient to nutrition-related complications
  • 9. SCIInflammation Malnutrition Loss of muscle mass Loss of activity Acute Illness & Nutritional Status After injury: weight loss due to loss of muscle or lean body tissue
  • 10. Complications with Loss of Lean Body Mass % Loss Total LBM Complications Associated Mortality % 10 Decreased immunity, Increased infections 10 20 Decreased healing, weakness, infection 30 30 Too weak to sit, pressure ulcers, pneumonia, no healing 50 40 Death, usually from pneumonia 100
  • 11. What is the best route of delivery: Enteral vs. Parenteral Enteral Nutrition (EN): Enteral nutrition is a treatment option when oral nutrition is unsafe due to aspiration risk or when the patient can no longer meet nutritional needs with an oral diet.
  • 12. Enteral Nutritional Support Continuous EN Better tolerated than bolus/intermittent EN in ICU setting Limit interruptions! Unnecessary for certain procedures—NPO at midnight should not be automatic Low rate of gastric residuals
  • 13. Benefits - EN Supports gut integrity Modulate stress and immune response Lower risk of infection than Parenteral Nutrition (PN) Reduction in hospital LOS  catabolism Improve the nutritional status (meet protein, energy and micronutrient requirements)  Infection Lower cost Quicker return of cognitive function (Taylor, et. al)
  • 14. Risks of EN Feeding when gut perfusion poor can lead to gut ischemia Feeding intolerance in critical illness May not reach nutritional goals as quickly as PN
  • 15. Parenteral Nutrition Benefits Fewer interruptions in feeding Nutrition goals reached quickly Least desirable Increased risk of infection Increased cost Increased risk of mortality
  • 16. SCI: Energy Needs in the Acute Phase Indirect calorimetry is considered to be the 'gold standard' and the only accurate and clinically feasible method of measuring energy expenditure in critically ill hypermetabolic patients It is called “indirect” because the caloric burn rate is calculated from a measurement of oxygen uptake. Used in both mechanically ventilated and spontaneously breathing patients (ventilated patients most accurate) Equipment is expensive and not readily available in the medical facilities
  • 17. SCI: Assessment: Energy Needs in the Acute Phase using Predictive Equations If Indirect Calorimetry is not available, the clinical dietitian may estimate energy needs with the Harris-Benedict formula using admission weight an injury factor of 1.2 an activity factor of 1.1
  • 18. Harris-Benedict Formula Basal Energy Expenditure Male: BEE = 66.67 + 13.75W + 5H - 6.76A Female: BEE = 665.1 + 9.56W +1.85H -4.68A H= height in centimeters W= weight in kg  A= age in years.
  • 19. SCI: Calculations of Energy Needs Harris-Benedict Formula Energy Needs = [BEE]) X (activity factor) X (injury factor) an injury factor of 1.2 an activity factor of 1.1
  • 20. SCI: Protein Needs in Acute Phase 2.0 g/kg of ideal body weight/day to minimize -ve nitrogen balance that occurs during the acute phase Status Estimated Requirements Normal (RDA) 0.8-1.0 g/kg/day Moderately stress 1.0-2.0 g/kg/day Severely stressed 2.0-3.0 g/kg/day Blackburn's General Guide for Protein Needs Based on Stress level
  • 21. SCI: Monitoring and Evaluation of Protein Intake in Acute Care Setting: Overfeeding 0 – 4 weeks post-injury : the clinical dietitian should monitor the patient's protein intake to ensure that the patient does not consume more than 2.0g/kg of body weight/day to achieve +ve nitrogen balance without any excessive nutrition support that may result in overload and metabolic complications
  • 22. Nutrition Management in the Rehabilitation Setting
  • 23. SCI: Goals of Nutrition Assessment in the Rehabilitation Setting Implementing an individualized therapeutic nutrition plan for the patient Improving transition into the community setting
  • 24. SCI: Energy Needs Patients with SCI have reduced metabolic activity due to denervated muscle Actual energy needs are at least 10% below predicted needs 22.7 kcal/ kg body weight for patients with quadriplegia 27.9 kcal/ kg for those with paraplegia Example: Patient weight 70 kg x 22.7 ≅ 1600 kcal/day energy needs for patient with quadriplegia
  • 25. SCI: Protein Needs in the Rehabilitation Setting (0.8 to 1.0) g/kg/day for maintenance of protein status in the absence of pressure ulcers or infection Example: Patient weight 70 kg x1 = 70 /day protein needs for patient with SCI
  • 27. SCI: Nutrition Assessment in the Community Setting Should be conducted as part of the annual medical exam Developing and implementing an individualized therapeutic nutrition plan necessary to identify secondary SCI conditions related to nutrition
  • 28. Secondary SCI Conditions Related to Nutrition 1. Metabolic Syndrome 2. Overweight and Obesity 3. Lipid Abnormalities 4. Pressure Ulcers 5. Bowel Problems 6. Urinary Tract Infections
  • 29. 1. Metabolic Syndrome  Metabolic Syndrome is not a single disease but a group of health problems that is believed to arise due to a combination of 1. Genetic factors 2. Lifestyle factors including overeating 3. Lack of physical activity
  • 30. Symptoms of Metabolic Syndrome 1. Waist Circumference greater than 102 cm for men and 88 cm for women (in SCI population it is likely a different estimation) 2. Triglyceride level ≥150 mg/dL 3. HDL < 40 mg/dL in men and <50 mg/dL in women 4. Blood pressure > 130/85 mmHg 5. Blood sugar > 110 mg/dL
  • 31. Dietary Recommendations to Prevent Metabolic Syndrome & Overweight/Obesity Limiting Fat Intake Choosing fat free or low fat dairy products Choosing lean meats and skinless poultry and fish Reducing Saturated Fat and Trans Fat These are the fats that are solid at room temp Animal fats Shortening Palm and coconut oil
  • 32. Dietary Recommendations to Prevent Metabolic Syndrome & Overweight/Obesity Eating less cholesterol Cholesterol is in foods from animal origin reducing the amount of saturated (animal fat) Increasing fruit and vegetable intake Limiting empty calories Choosing water or diet beverages over regular soda & reducing the amount of sweets & sugars & alcohol
  • 33. For the general population overweight and obesity can be categorized by using BMI BMI<18.5- Underweight BMI 18.5-24.9- Normal Weight BMI 25-29.9- Overweight BMI 30-39.9- Obese BMI >40- Extreme Obese 2. Overweight and Obesity
  • 34. SCI: Assessment of Body Composition: BMI and skinfold measurements The clinical dietitian should not use the following to measure body composition in persons with SCI:  body mass index (BMI) Skinfold measurements These methods may not provide reliable results since they were developed based on able- bodied persons.
  • 35.
  • 36. SCI: Estimation of Ideal Body Weight Quadraplegia or (Tetraplagia): Reduction of 10% to 15% (7-9) kg lower than table weight Paraplegia: Reduction of 5% to 10% (4.5-7) kg lower than table weight
  • 37. Estimation of Ideal Body Weight The clinical dietitian should estimate ideal body weight for persons with SCI by adjusting the Metropolitan Life Insurance tables for individuals of equivalent height and weight
  • 38. Height (m) Frame Size Medium Large Para Tetra Para Tetra 1.57 49 46.5 54.5 52 1.60 51 49 57 55 1.62 54.5 52 60 58 1.65 57 55 63.5 61 1.67 60 58 66 64 1.70 62 60 69 67 1.72 65 63 72 69 1.75 68.5 66 75 73 1.77 75 68 78.5 76 1.80 73.5 71 81 78.5 1.83 76 74 85 82 1.86 79 77 87 85 1.88 81 79 90 88 1.91 84 82 93.5 91 1.93 86.5 85 96 94 1.96 90 88 99 97 1.98 92 90 102 99.5 S C I M E N W E I G H T T A B L E S
  • 39. S C I W O M E N W E I G H T T A B L E S Height (m) Frame Size Medium Large Para Tetra Para Tetra 1.47 36 34 40 38 1.5 38.5 36 43.5 41 1.52 41 39 45 43 1.55 43.5 41 48.5 46 1.57 45 43 46 48 1.60 47 45 53.5 51 1.62 50 48 55.5 53 1.65 52 49 57.5 55 1.67 54.5 52 60.5 58 1.70 56 54 63 61 1.72 59.5 57 65 63 1.75 61 59 68 66 1.77 63.5 61 70 68 1.78 66 64 73.5 71 1.83 68.5 66 75 73
  • 40. SCI: Assessment of Body Composition: BIA and DEXA  Assessment of body composition for medically stable SCI patients by using Bio-electric Impedance Analysis (BIA) Dual-Energy X-Ray Absorptiometry (DEXA) Persons with SCI have significantly higher fat mass and lower lean mass than persons without SCI
  • 42. What’s the difference between weight & body fat in terms of health risks? Weight measurement alone cannot accurately determine a person’s body fat % and the resulting health risks  New evidence indicates that fat loss, not weight loss can extend lifespan
  • 43. Level of Body Fat % for General Health Adult Male Adult Female Age Excellent Good Average Poor Age Excellent Good Average Poor 19-24 10.8% 14.9% 19.0% 23.3% 19-24 18.9% 22.1% 25.0% 29.6% 25-29 12.8% 16.5% 20.3% 24.4% 25-29 18.9% 22.0% 25.4% 29.8% 30-34 14.5% 18.0% 21.5% 25.2% 30-34 19.7% 22.7% 26.4% 30.5% 35-39 16.1% 19.4% 22.6% 26.1% 35-39 21.0% 24.0% 27.7% 31.5% 40-44 17.5% 20.5% 23.6% 26.9% 40-44 22.6% 25.6% 29.3% 32.8% 45-49 18.6% 21.5% 24.5% 27.6% 45-49 24.3% 27.3% 30.9% 34.1% 50-54 19.4% 22.7% 25.6% 28.7% 50-54 26.6% 29.7% 33.1% 36.2% 54-59 20.2% 23.2% 26.2% 29.3% 54-59 27.4% 30.7% 34.0% 37.3% 60 20.3% 23.5% 26.7% 29.8% 60 27.6% 31.0% 34.4% 38.0%
  • 44. Example Patient: 30 years old male BMI= 17.9 Underweight Average % fat assessed: 28.2% This would make this patient obese because in this age group the amount of fat that is considered acceptable is 18-25%, making this seemingly underweight patient obese
  • 45. SCI: Risks Associated Overweight & Obesity The SCI patients is at a higher risk of associated comorbidities Diabetes Metabolic syndrome Cardiovascular disease Lower levels of spontaneous physical activity and a lower thermic effect of food result in decreased energy expenditure and energy needs.
  • 46. What is the Thermic Effect of Food? It is a reference to the increase in metabolic rate (i.e. the rate at which your body burns calories) that occurs after ingestion of food. Energy expenditure (i.e. calories) to digest, absorb, and store the nutrients; accounts for 5 to 10 % of the energy content of the food ingested. Example 500 calorie meal, 50 calories (or 10%) would be expected to be burned due to the thermic effect of food, a net calorie consumption of 500 - 50 = 450 calories.
  • 47. Influence of Body Composition on the Thermic Effect of Food Lean people have a thermic effect of food 2 to 3 X greater than obese or people with higher body fat %, during rest, after exercise, and during exercise. Segal KR, Gutin B, Albu J, Pi-Sunyer FX. Thermic effects of food and exercise in lean and obese men of similar lean body mass. Am J Physiol. 1987 Jan;252(1 Pt 1):E110-7.
  • 48. SCI: Wheel Chairs & Energy Needs Compared to ultralight wheelchairs and pushrim- activated, power-assisted wheelchairs; The use of a manual standard wheelchair increases: Energy needs  heart rate Oxygen consumption and ventilation, especially as speed and resistance levels increase
  • 49. SCI: Nutrition Education Regarding Physical Activity physical activity should be encouraged as part of a comprehensive weight management program for overweight or obese SCI patients
  • 50. Physical Activity for SCI Patients Swimming Electrical stimulation exercise Body weight supported Treadmill training
  • 51. 3. Lipid Abnormalities SCI patients are at higher risk of cardiovascular conditions. Cardioprotective diet should be provided if total cholesterol levels > 200mg/dL
  • 52. SCI: Factors Related to Lipid Abnormalities Age Ethnicity Gender Time since injury Level of injury Activity level Dietary habits Smoking behavior Alcohol intake Overweight or obese status ModifiableNon-Modifiable
  • 53. SCI: Nutrition Screening for Lipid Abnormalities Screening for lipid abnormalities is recommended for all persons with SCI in order to reduce morbidity and mortality.  Up to 30% deaths from CHD due to an unhealthy diet  36% due to inactivity NHF (2006)  Up to 30% deaths from CHD due to an unhealthy diet  36% due to inactivity NHF (2006)
  • 54. 4. Pressure Ulcers Patients who are at the greatest risk of developing pressure ulcers Nonambulatory Compromised nutritional status Pressure ulcers are secondary to the decrease in oxygen supplied to at- risk areas (eg, coccyx, elbows, heels) Modifiable
  • 55. SCI: Nutrition Prescription for SCI Persons with Pressure Ulcers A nutrition prescription should be formulated as part of the nutrition intervention for persons with (SCI) and pressure ulcers Energy Protein Fluid Micronutrient requirements Additional energy and protein is needed for optimal healing of pressure ulcers Fluid and micronutrient needs will vary depending on the person's status.
  • 56. Nutritional Assessment The Clinical Dietitian should assess for:  Anthropometrics Skin integrity Dietary intake Lifestyle factors Biochemical indices
  • 57. SCI: Biochemical Parameters Associated with Prevention of Pressure Ulcers laboratory indices associated with the risk of pressure ulcers albumin, Prealbumin, Zinc, vitamin A and vitamin C Biochemical parameters as close to normal as possible or within the normal range are associated with reduced risk of pressure ulcers.
  • 58. Serum Albumin Hypoalbuminemia, has been associated with the development and progression of pressure ulcers.  Nutritional intervention needs to include adequate protein and adequate calories to spare protein for wound healing. The goal is a serum albumin of greater than 3.5 g/dL The amount of protein and number of calories need to increase as the stage of the ulcer increases
  • 59. SCI: Assessment: Energy Needs with Pressure Ulcers SCI patients with pressure ulcers have higher energy needs Additional energy is needed for optimal healing 30 – 40 kcal/kg of body weight/day Harris-Benedict x Stress Factor 1.2 for stage II ulcer 1.5 for stage III and IV ulcers
  • 60. SCI: Assessment: Protein Needs with Pressure Ulcers The clinical dietitian should calculate protein needs as follows: (1.2 - 1.5)g of protein/kg body weight/day (Stage II pressure ulcers) (1.5 - 2.0)g of protein/kg body weight/day (Stage III and IV pressure ulcers).
  • 61. Arginine Dietary supplementation with arginine has been shown to enhance protein metabolism, helping to decrease muscle loss, and collagen synthesis, which helps to increase the strength of the wound Increased protein demand for normally nonessential amino acids, becomes essential (conditionally essential) Increases IGF-1 (Insulin Like Growth Factor) level hormone that promotes wound healing Studies suggest +ve outcomes in post-op surgical wounds. L-Arginine is also effective in healing chronic ulcers in people with diabetes (ultimately helping to reduce leg amputations)
  • 62. When and How to Use Arginine Should NOT be first line of defense Consider for non-healing wounds after calorie and protein needs met Therapeutic dose to promote healing is ~9 grams/day
  • 63. Side effects L-Arginine supplementation can cause diarrhea. Gradual increase of daily dose may help tolerance.
  • 64. Glutamine Functions Regulates amino acid homeostasis Preferred energy source for rapidly multiplying cells of intestinal mucosa and immune system May stabilize the intestinal barrier, reducing risk of bacterial translocation and systemic inflammatory response [Neu 2002] Clinical trials of supplementation suggest benefit but remain inconclusive.
  • 65. How and When to Use Glutamine This is NOT first line of defense Indications are for patients with GI impairment and Immune deficiencies Provide 15-30g/day or 0.57 gm/kg wt
  • 66. ß-Hydroxy-ß-methyl-butyrate (HMB) Substance derived from breakdown of amino acid leucine Function Anti-catablic agent Used for reduction of muscle tissue breakdown Lack of clinical trials available Some Products are marketed for wound healing Contains 7 gm arginine, 7 gm glutamine, 1.5 g HMB per packet
  • 67. SCI: Fluid Needs with Pressure Ulcers The clinical dietitian should assess hydration status to determine fluid needs. evaluation of parameters such as input and output urine color skin turgor BUN serum sodium
  • 68. Fluid Needs with Pressure Ulcers Normal requirement: (30 – 40)ml/kg Minimum of 1 ml/kcal/day (10 – 15) ml per kg additional fluids may be required with the use of air fluidized beds set at a high temp. (more than 31º to 34ºC Fluid loss also includes evaporation from open wounds, wound drainage and fever
  • 69. SCI: Nutrition Support & Pressure Ulcers Implementing aggressive nutrition support measures for SCI patients at risk of pressure ulcer development may include (Enteral and Parenteral Nutrition) Improved nutrition intake, body weight and biochemical parameters are associated with reduced risk of pressure ulcer development
  • 70. SCI: Micronutrients & Wound Healing Daily vitamin and mineral supplement should not be more than 100% of the RDA.  When supplementing greater than the Tolerable Upper Intake Level (UL); the dietitian should re- evaluate the need for micronutrient supplementation every 7 to 10 days.
  • 71. Vitamin A Stimulates differentiation in fibroblasts and collagen synthesis to quicken healing Vitamin A deficiency results in impaired wound healing and alteration in immune function that may increase wound infections. Recommendations for amount of Vitamin A is (10,000 IU to 50,000 IU /day) 10,000 IU IV for moderate-severely injured patients or malnourished patients for a limit of 10 days.
  • 72. Vitamin A & Steroids For patients receiving steroids, 10,000 IU to 15,000 IU for one week has been recommended to counteract the anti- inflammatory effects of steroids Steroids adversely affect all phases of wound healing and increase risk of infection[Ross 2002] Vitamin A supplementation should be implemented cautiously because of potential toxicity
  • 73. Vitamin C Necessary for collagen synthesis Enhances immune function  Depressed levels found in elderly, smokers, and certain cancers [Ross 2002] Vitamin C deficiency has been associated with delayed wound healing High doses of Vitamin C for healing chronic wounds is recommended (100 to 200)mg/day of Vitamin C for Stage I and II pressure ulcers (1,000 to 2,000) mg/day of Vitamin C for Stage III and IV pressure ulcers
  • 74. Zinc Zinc deficiency is associated with delayed wound healing due to a decrease in collagen protein synthesis and impaired immune competence. (50mg elemental Zinc) twice/day is recommended as a standard adult oral replacement (minimal daily requirements is 15 mg/d) High-dose supplementation of zinc should be limited to (2-3) weeks Dosage should be individualized according to zinc status and metabolic demands.
  • 75. Iron Anemia assessed by hemoglobin and hematocrit levels If low hemoglobin concentration is due to iron deficiency anemia, it may be a factor in tissue hypoxia and impaired wound healing. Supplementation should be provided as indicated to correct iron deficiency anemia. There are 58 studies about curcumin & wound healing in the PubMed until this date 30/6/2011
  • 76. Recent Researches A search of PubMed on the internet reveals some 58 scientific and technical papers referenced to curcumin and wound healing
  • 77. Curcumin & Wound-healing Dermal wound healing processes with curcumin incorporated collagen films Gopinath D.etal Biomaterials. 2004 May;25(10):1911-7 Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing Phan TTetal J Trauma. 2001 Nov;51(5):927-31 Enhancement of wound healing by curcumin in animals Sidhu G Setal , Wound Repair Regen. 1998 Mar-Apr;6(2):167-77 Inhibitory effect o fcurcuminon PMA-induced increase in ODC m RNA in mouse epidermis Lu YP…Conney AH, Carcinogenesis. 1993 Feb;14(2):293-7 Inhibitory effect of dietary curcuminon skin carcinogenesisin mice LimtrakulP., CancerLett. 1997 Jun 24;116(2):197-203 Turmeric and curcuminas topical agents in cancer therapy KuttanR.,Tumori. 1987 Feb 28;73(1):29-31
  • 78. 5. Neurogenic Bowel The Clinical Dietitian should prescribe for SCI patient with neurogenic bowel an initial fiber intake of 15g/day, with gradual increases up to 30g/day of fiber, as tolerated from a variety of sources. Excessive fiber may result in unacceptable Flatulence Significant increase in stool volume Painful abdominal distension
  • 79. 5. Neurogenic Bowel Fiber intake > 20g/day may be associated with undesirable prolonged intestinal transit times resulting in excessive fluid reabsorption and the formation of hardened stools Transit TimeTransit Time
  • 80.
  • 81.
  • 82. Constipation Juices, especially those high in sorbitol, can help relieve constipation.
  • 83. Juices that are Good for Chronic Constipation Sorbitol is a natural fruit sugar that is poorly absorbed by the intestines, so it stays in the intestinal tract and makes the stools more liquid
  • 84. Prune juice Prune juice contains 6.1 g of sorbitol /100-g serving Prune juice and other prune products have long been used to relieve constipation due to their laxative effect An added benefit of prune juice over many other fruit juices is that it does not cause a spike in blood sugar, which can be dangerous for diabetics. Baylor College of Medicine
  • 85. Pear Juice One 8-oz glass of pear juice can contain as much as 7 g of sorbitol. As few as 10 g of sorbitol can cause diarrhea in children (it is best to offer a child only a small amount to assist in chronic constipation relief) Baylor College of Medicine
  • 86. Apple Juice Apple juice is naturally high in sorbitol It is a mild juice that can cause gas in some individuals it is often one of the first juices given to babies who have constipation It is suggested to give babies 2 oz of apple juice twice per day for constipation
  • 87. Constipation  Foods (such as dairy products, white potatoes, white bread and bananas) can contribute to constipation  Foods (such as excess amounts of fruit, caffeine, or spicy foods and warm fluids with lemon juice) may soften the stool or cause diarrhea
  • 88. Constipation  Drinking water and eating high-fiber foods such as fruits, vegetables, whole grains and legumes may help to soften and make the stool bulkier, which stimulates movement of the bowel  Peristalsis can be stimulated with vegetables, fruits (especially dried fruits)  Dried fruits are the ideal substitute for candies
  • 89. SCI: Fluid & Neurogenic Bowel: Estimating Fluid Needs to Promote Optimal Stool Consistency 1 ml fluid/kcal estimated energy needs + 500 ml Example  1500 fluid/kcal estimated energy needs+ 500 ml= 2000 ml fluid Needs/day 30-40ml/kg body weight + 500 ml Example  40 x 55 kg body weight + 500 ml = 2700 ml fluid needs/day
  • 90. SCI: Fluid & Neurogenic Bowel:
  • 91. 6. Urinary Tract Infections The Clinical Dietitian may recommend that cranberry juice be included in the diet to reduce urinary tract infections Consumption of one cup (250ml) cranberry juice, 3 times/day, may be associated with a reduced urinary tract biofilm load Cranberry juice contains hippuric acid and another substances that seems to prevent adherence of bacteria to urinary tract epithelial
  • 92. SCI: Cranberry Extract Supplements The Clinical Dietitian should not recommend cranberry extract supplements to promote urologic health (prevention of urinary tract infections, urologic stones, etc.) with SCI patients  Cranberry extract supplements, ingested in tablet or capsule form, are not effective in prolonging the UTI-free period or decreasing bacteriuria or WBC count in persons with SCI patients
  • 94.
  • 95.

Notes de l'éditeur

  1. How much nutritional needs change has not been well studied in SCI patients but we do know that they change. Today, specifically I am going to focus on calories because for the most part protein and fluid needs stay about the same. However, I will mention that if you are increasing protein in your diet you need to increase fluid (water) at the same time because of the damage that high protein diets can do to your kidneys. Metabolism is a complicated chemical process so I am going to explain it in simple terms that all of us will remember. The amount of calories that a person burns in a day is affected by how active that person is, the amount of fat and muscle in their body, and their basal metabolic rate, which is how many calories we are burning while we are at rest.
  2. Indirect calorimetry relies on the fact that burning 1 calorie (Kilocalorie) requires 208.06 milliliters of oxygen. Because of this very direct relationship between caloric burn and oxygen consumed, measurements of oxygen uptake (VO2) and caloric burn rate are virtually interchangeable. Oxygen uptake requires a precise measurement of the volume of expired air and of the concentration of oxygen in the expired air.
  3. These are some of the problems that I mentioned on the last slide that we are particularly concerned about. I am not going to go into great detail about any of the secondary conditions related to SCI and nutrition. However, I am going to highlight the words listed in red related to the metabolic syndrome because this is something many of you may be unfamiliar with.
  4. Metabolic syndrome which puts you at greater risk for cardiovascular disease, other heart disease, diabetes and other complications.
  5. Metabolic syndrome which puts you at greater risk for cardiovascular disease, other heart disease, diabetes and other complications.
  6. Removing the skin cuts the amount of fat in half!!
  7. Removing the skin cuts the amount of fat in half!!
  8. to 10 % of the energy content of the food ingested. This would mean, for example, that if you eat a 400 calorie meal, you can reasonably expect somewhere between 20 to 40 calories to be burned in the process of digesting, absorbing, and storing the nutrients from the meal. Or, as another example, if you eat 2000 calories per day, roughly 100 to 200 calories will be burned each day as a result of the thermic effect of food.
  9. to 10 % of the energy content of the food ingested. This would mean, for example, that if you eat a 400 calorie meal, you can reasonably expect somewhere between 20 to 40 calories to be burned in the process of digesting, absorbing, and storing the nutrients from the meal. Or, as another example, if you eat 2000 calories per day, roughly 100 to 200 calories will be burned each day as a result of the thermic effect of food.
  10. to 10 % of the energy content of the food ingested. This would mean, for example, that if you eat a 400 calorie meal, you can reasonably expect somewhere between 20 to 40 calories to be burned in the process of digesting, absorbing, and storing the nutrients from the meal. Or, as another example, if you eat 2000 calories per day, roughly 100 to 200 calories will be burned each day as a result of the thermic effect of food.
  11. Figure 20.4: The Spinal Cord.