Presentation by Bioptigen at OIS@ASRS 2016. Participant: Eric Buckland, CEO - Bioptigen Powered by: Healthegy For more ophthalmology innovation Visit us at www.ois.net

1. Bioptigen
Eric Buckland
Co-Founder and CEO
EnFocus OCT
The Future of Surgical Imaging

2. Optical Coherence Tomography
… because Images Matter
 Founded 2004
 Duke University (Joe Izatt)
 2006 First 510(k) Dual Retina/Cornea OCT
 2012 First 510(k) Pediatric Handheld OCT
 2015 First 510(k) Surgical Retrofit OCT
 East Coast Angel Funded
 Brien Holden Vision Institute
 NEI SBIR (2 Phase II, 1 FastTrack)
 50+ Patents
 Frost & Sullivan Awards 2007 & 2015
Bioptigen Acquired by Leica Microsystems June 2015
… because Images Matter
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3. Envisu C2300 Accelerates Intrasurgical OCT
Pre
Post
Images courtesy Dr. Justis Ehlers
Pre
Post
*Cleveland Clinic PIONEER Study

4. EnFocus – made great by design
OCT
Objectiive
Oculars
 Maximum Scan Range
 Coaxial and Telecentric
 Latency-Free Imaging
 OCT Focus and DoF
Resolution: < 4 mm
Depth: 2.5 mm
ENFOCUS Ultra HD OCT ENFOCUS Ultra Deep OCT
Resolution: < 9 mm
Depth: 11 mm
*Depth and resolution as measured in tissue

5. EnFocus 4400 Ultra Deep
Full Depth Anterior Imaging
Images courtesy Dr. Mathew Kurian, Narayana Nethralaya

6. EnFocus 4400 Ultra Deep
Retinal Stem Cell Research
Images courtesy Dr. Juan Amaral, NEI NEI Stem Cell Research, porcine models

7. 7
EnFocus 2300 High Definition
Macular Hole Buckle Placement
Images courtesy Dr. Barbara Parolini, Brescia

8. A. Prepare cornea
B. Prepare donor tissue
C. Place donor tissue
D. Smooth, remove air
E. EVALUATE
A B
C D E
EnFocus 2300 High Definition
DSAEK Cornea Transplant

9. What Will You Do
Differently …
With Your Surgical Field
EnFocus ?