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Community-Based Therapeutic Care
  of Severe Acute Malnutrition in
     Oromiya Region, Ethiopia




         Presented By: Team 1
   Adam Scott, Angela Montesanti, Carol
   Combs, Samuel Gentle, Susie Harvey
                                          1
Ethiopia Health Statistics: At a Glance
•   Birth Rate: 43.66 births / 1,000 population (#7 highest in the world)
•   Infant Mortality Rate: 80.8 deaths / 1,000 live births (#18 highest in the world)
•   Total Fertility Rate: 6.12 children born / woman (#9 highest in the world)


                 General Information: Oromiya State
•   Population: 28 million people
•   86.2% population live in rural areas
•   95% of energy produced from hydroelectric power
•   Agriculture = 45% GDP; 85% total employment
•   “breadbasket of the Horn”
•   Oromo ethnic group = 32.1% total population of Ethiopia; Oromo language is the 3rd
    most common language in Africa
•   Oromos currently marginalized by national government because of their national
    liberation movement called Oromo Liberation Front (OLF)


                                                                                         2
Severe Acute Malnutrition
Severe Acute Malnutrition (SAM) is an urgent, life-threatening condition characterized
by one or several of the following:
     Visible severe wasting
     A Weight-for-height ratio below 3 standard deviations of the median WHO growth
     standards
     A MUAC <110mm
     Presence of nutritional edema
Children with SAM have a 9.4 fold higher rate of mortality compared to their non-
malnourished counterparts.




                                                                                          3
                           http://www.savethechildren.org.uk/en/9245.htm
Two Approaches

Inpatient Treatment                Community-based Management
• Hospital care for SAM has a      • Care for non-complicated
   significantly reduced             cases of SAM in the child’s
   mortality for children. With      community/home with the
   treatment including               use of RUTFs
   therapeutic diet and care       • Outcomes comparable to
   for any co-morbidities            inpatient care
• Limited usefulness due to        • Drawbacks:
   lack of facilities, man-power      – Complicated Cases
   and high cost                      – Education
                                      – Screening
                                                                   4
Location of Intervention




                           5
Arsi Negele
• Presence of Medicins Sans Frontieres (Doctors Without Borders)
• Lack of NGO involvement compared to similarly affected regions in the
  area
• High prevalence of severe malnutrition in children
• Proximity to the airport
• “A recent mass screening in Siraro, Shalla, Arsi Negele, Shashemene and
  Adaba in West Arsi zone through Enhanced Outreach Strategy (EOS) by the
  regional and zonal administration supported by UNICEF has revealed that
  out of 184,670 children screened, a total of 4,614 children (2.5 per cent)
  have been identified as severely malnourished. Response is ongoing
  accordingly.”




                                                                           6
Director
                                                       MD/MPH


                                                  Assistant Directors


                                                      Finance and       Awareness and
                                Medical Officer
                                                        Logistics       Public Relations
                                  CRNP/BSN
                                                         MBA                 MPH



                                   Recruiter




 Community       Community        Community           Community              RUTF
Health Worker   Health Worker    Health Worker       Health Worker        Production
     1                2                3                   4               Manager




  Women           Women            Women               Women
                                                                            Farmers
  worker(s)       worker(s)        worker(s)           worker(s)


                                                                                           7
Phases of Action

                                    Sustainability
                        Follow Up   (continuous)
              Action    (2 mos)
              (2 mos)
Preparation
(1-2 mos)

                                                     8
Phase I – Preparation
     Recruitment
     CHW Training
 Community Assessment
   Promotion Teams
     Local Teams
   Educate Mothers



                         9
Recruitment

   • Recruitment officer will
     seek out community
     health workers currently
     practicing in urban areas
     of Ethiopia
   • These individuals will be
     paid a salary and will be
     housed at our location

                                 10
Community Assessment
• During recruitment efforts, the recruitment
  officer will also be in charge of identifying
  suitable living arrangements for the CHWs, as
  well as storage facilities for supplies
• Proper locations for secondary screenings will
  also be necessary during this time



                                                   11
CHW Training
• CHWs will be taught about SAM, along with
  the necessary protocols with which to identify
  children who have SAM
  – MUAC < 110mm
  – Bipedal edema
• In addition, CHWs will be educated on other
  public health measures such as clean water
  and sanitation

                                                12
Promotion Team
• While recruitment and education initiatives
  are underway, a promotion team will be
  enlisted.
• The purpose of this team will be to begin to
  promote the large-scale secondary screening
  to come in the following weeks to evaluate
  children who meet SAM criteria


                                                 13
Local Teams
• Once adequately trained, CHWs will seek out
  community leaders and healers to form a local
  team of screeners and educators
• CHWs will be in charge of educating these
  locals, predominately women and mothers, to
  screen for SAM and to educate on public
  health issues


                                              14
Mothers in the Community
• After becoming proficient in methods of
  detecting and educating, these local teams
  will disperse into their respective
  neighborhoods and will begin teaching
  mothers there utilizing the Hearth Model
• These mothers will then be capable of
  recognizing SAM and knowing what to do and
  where to go

                                               15
PHASE II: Action




                   16
Education             Intervention Flow Chart

                  Complicated
                                    Referred
   1⁰ and 2⁰
                     SAM
Rapid screening
                  Uncomplicated                      Weekly
                                  Weekly Supply
                      SAM                            Checkup


                                                  education and check
                                                   for improvement

    Not SAM
                                                  Not improved within
                                                        3 weeks




Parents at home                                        Referred
   screening
  prevention                                                       17
At Home Screening

MUAC <110 mm      Yes      SAM:
     OR                 2 Screening
   edema


  No



   MUAC
 Surveillance
                                      18
2 Screening
                                              Non-
        Complicated              SAM       complicated




     1: Grade 3 pitting edema
                 OR
                                         1: MUAC < 110
2: MUAC <110 & Grade 1/2 edema
                 OR
                                               OR
   3: MUAC <110 & one of the
             following:
                                        2: MUAC 110 w/
             •Anorexia
                                        Grade 1/2 edema
        •Lower Respiratory
                                               AND:
          Tract Infection
                                            •Appetite
      •Severe palmar pallor
                                          •Clinically well
            •High fever
                                              •Alert
       •Severe dehydration
             •Not alert
                                                             19
2 Screening
– Non-complicated cases:
  • Weight assessment
  • Give weekly supply of prophylactic antibiotics, RUTF’s
    (purchased from local manufacturers), & food ration for
    family
  • Detailed instructional component
  • Set up weekly follow-up for monitoring




                                                          20
PHASE III: Follow Up




                       21
Monitoring
• Will consist of 4 procedures:
   –   Weekly recorded measurements
   –   Screening for potential complications
   –   Deferment to MSF for treatment of complicated SAM
   –   Providing the next week’s provisions
• Will occur at all 4 centers in Arsi Nigele 5 days a
  week (with an estimated child load of 300
  children/day)
• If fewer designated days are desired by mothers,
  we will accommodate them
                                                           22
Monitoring: Weekly Progress
1) Weight gain: WHO Standards of Weight Gain:




2) Pitting Edema:
         -reduction or disappearance
                                                23
Monitoring: Screening for
             Complications
• For those that are failing to improve,
  determine the etiology:
  – Inappropriate administration
  – Non-compliance
  – Underlying Infection
  – Missed complication




                                           24
Reporting and Outcome Evaluation
• Send out weekly progress
  reports to the Phil and Linda
  Bates Foundation, as well as
  local consensus agencies,
  UN, etc.
   – Weight changes
   – Presence and grade of edema
   – Complication rates
• Outcome evaluation
   – DALYs
   – Mortality & morbidity
     rates

                                   25
Phase IV: Sustainability




                           26
Local RUTF Production
• Use of locally grown crops to produce RUTF
• Crop growth will occur concurrently with
  purchased RUTF treatment
• Additional crops will be grown to fund RUTF
  components not immediately available




                                                27
Components of RUTF




• Sugar and oil are made locally within the region
• Peanuts are made in Addis Ababa
• Soy production will soon begin locally via an Indian manufacturer Ruchi Soya
 ***Due to the high cost of milk, soy products will be substituted




                                                                                 28
Local Production
    • Production specifics will reflect those
      outlined in Manary’s article in Food
      and Nutrition Bulletin
    • Quality control will be maintained
      based on the protocols outlined




Manary. 2006. Local production and provision of ready-to-use therapeutic food (RUTF) spread
for the treatment of severe childhood malnutrition. Food and Nutrition Bulletin, vol 27; 3.
                                                                                       29
Collaboration Efforts
• Doctors Without Borders:
  – Referral Clinic(s)


• GAVI government partnerships:
  – Incentive for families to participate (receive food AND
    vaccinations)
  – Share resource costs

• UNICEF/UN WFP:
  – Partnership for food distribution to families

                                                              30
$1.0 million Budget

$200,000
     Salaries (Director, ADs, CHWs, Local Outreach Workers)
 $300,000
   Treatment (RUTFs, supplemental medications/therapies, food for families)
 $200,000
   Transportation, Housing, Rent, Medical supplies, MUACs, Other
 $300,000
   Agriculture Sustainability measures (industrial mixers, seeds, etc)




                                                                              31
Benefits
       PHASE I:                           PHASE II:

      • Location                       • Cost effective

     • Replicable                        •Save lives

•Education of women                 •Community investment




      PHASE III:
                                          PHASE IV:
•Adequate monitoring
                                       • Sustainability
•Preventative measures
                                • Decreased incidence of SAM
• Increased compliance

                                                               32
Limitations
          PHASE I:                         PHASE II:

   • Lack of participation      • Opportunity costs to parents
                                  referred to clinical facilities
• Noncompliance to screening
        procedures                • Underlying complications




         PHASE III:                        PHASE IV:

 • Accuracy of outcome data    • RUTF Manufacturing: need to
                                  buy vitamin supplements

   • Long term follow up               • Transport costs

                                                                    33
References
•   World Health Organization. Management of severe malnutrition: a manual for physicians and other senior health workers. Geneva, 1999.

•   RE Black, LH Allen, ZA Bhutta et al. and for the Maternal and Child Undernutrition Study Group, Maternal and child undernutrition: global and
    regional exposures and health consequences, Lancet 371 (2008), pp. 243–260.

•   Bhutta Z, Ahmed T, Black RE, Cousens S, Dewey K, Giugliani E, Haider BA, Kirkwood B, Morris SS, Sachdev HPS, Shekar M, Maternal and Child
    Undernutrition Study Group: What works? Interventions for maternal and child undernutrition and survival. Lancet 2008, 371:417-440.

•   Bahwere P, Binns P, Collins S, Dent N, Guerrero S, Hallam A, Khara T, Lee J, Mollison S, Myatt M, Saboyo M, Sadler K, Walsh A: Community Based
    Therapeutic Care. A Field Manual. Oxford, Valid International; 2006.

•   Prudhon C, Prinzo Z, Briend A, Daelmans B, Mason J. Proceedings of the WHO, UNICEF, and SCN Informal Consultation on Community-Based
    Management of Severe Malnutrition in Children. Food and Nutrition Bulletin 2006; 27(3):S99-S108.

•   Nutrition Working Group, Child Survival Collaborations and Resources Group (CORE), Positive Deviance / Hearth: A Resource Guide for Sustainably
    Rehabilitating Malnourished Children, Washington, D.C: December 2002.

•   Humanitarian Bulletin. UN Office for Coordination of Humanitarian Affairs. 18 May 2009.

•   http://www.doctorswithoutborders.org/news/article.cfm?id=2727

•   http://www.gavialliance.org/resources/Ethiopia_GAVI_Alliance_country_fact_sheet_June_2008_ENG.pdf

•   http://www.unicef.org/infobycountry/files/ETHIOPIA_UNICEF_HAU_12_March_2009.pdf


•   World Health Organization. Management of the child with a serious infection or severe malnutrition: Guidelines for care at the first referral level in
    developing countries. 2000. Accessed February 19, 2010. http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.1.pdf


•   Collins, Steve, et Al., (2005). Key issues in the success of community-based management of sever malnutrition. Valid
    International Ltd.




                                                                                                                                                         34
Appendix




           35
36
37
38
DALY’s: Disability Adjusted Life Years
   • Measures overall disease burden
   • Combines mortality and morbidity into one measurement
   • DALY = YLL +YLD
        – YLL: years of life lost
             • YLL = N * L        N: # deaths
                                  L: Standard Life Expectancy
             • YLD = I * DW * L         I: Incidence Cases
                                       DW: Disability Weight ( 0 = perfect health
                                                                      1 = equivalent to
        Distribution Weights                                              death
                                                    -disease severity
           Wasting: 0.053                    L: avg duration of case until remission or
           Stunting: 0.002                      death
      Develop. Disability: 0.024
 Cretinism (Iodine Deficiency): 0.804
Corneal Scar (Vit. A deficiency): 0.277
Severe Iron deficiency anemia : 0.090
       Cognitive Impair.: 0.024
                                                          WHO & Global Burden of Disease 2004

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Team one case

  • 1. Community-Based Therapeutic Care of Severe Acute Malnutrition in Oromiya Region, Ethiopia Presented By: Team 1 Adam Scott, Angela Montesanti, Carol Combs, Samuel Gentle, Susie Harvey 1
  • 2. Ethiopia Health Statistics: At a Glance • Birth Rate: 43.66 births / 1,000 population (#7 highest in the world) • Infant Mortality Rate: 80.8 deaths / 1,000 live births (#18 highest in the world) • Total Fertility Rate: 6.12 children born / woman (#9 highest in the world) General Information: Oromiya State • Population: 28 million people • 86.2% population live in rural areas • 95% of energy produced from hydroelectric power • Agriculture = 45% GDP; 85% total employment • “breadbasket of the Horn” • Oromo ethnic group = 32.1% total population of Ethiopia; Oromo language is the 3rd most common language in Africa • Oromos currently marginalized by national government because of their national liberation movement called Oromo Liberation Front (OLF) 2
  • 3. Severe Acute Malnutrition Severe Acute Malnutrition (SAM) is an urgent, life-threatening condition characterized by one or several of the following: Visible severe wasting A Weight-for-height ratio below 3 standard deviations of the median WHO growth standards A MUAC <110mm Presence of nutritional edema Children with SAM have a 9.4 fold higher rate of mortality compared to their non- malnourished counterparts. 3 http://www.savethechildren.org.uk/en/9245.htm
  • 4. Two Approaches Inpatient Treatment Community-based Management • Hospital care for SAM has a • Care for non-complicated significantly reduced cases of SAM in the child’s mortality for children. With community/home with the treatment including use of RUTFs therapeutic diet and care • Outcomes comparable to for any co-morbidities inpatient care • Limited usefulness due to • Drawbacks: lack of facilities, man-power – Complicated Cases and high cost – Education – Screening 4
  • 6. Arsi Negele • Presence of Medicins Sans Frontieres (Doctors Without Borders) • Lack of NGO involvement compared to similarly affected regions in the area • High prevalence of severe malnutrition in children • Proximity to the airport • “A recent mass screening in Siraro, Shalla, Arsi Negele, Shashemene and Adaba in West Arsi zone through Enhanced Outreach Strategy (EOS) by the regional and zonal administration supported by UNICEF has revealed that out of 184,670 children screened, a total of 4,614 children (2.5 per cent) have been identified as severely malnourished. Response is ongoing accordingly.” 6
  • 7. Director MD/MPH Assistant Directors Finance and Awareness and Medical Officer Logistics Public Relations CRNP/BSN MBA MPH Recruiter Community Community Community Community RUTF Health Worker Health Worker Health Worker Health Worker Production 1 2 3 4 Manager Women Women Women Women Farmers worker(s) worker(s) worker(s) worker(s) 7
  • 8. Phases of Action Sustainability Follow Up (continuous) Action (2 mos) (2 mos) Preparation (1-2 mos) 8
  • 9. Phase I – Preparation  Recruitment  CHW Training  Community Assessment  Promotion Teams  Local Teams  Educate Mothers 9
  • 10. Recruitment • Recruitment officer will seek out community health workers currently practicing in urban areas of Ethiopia • These individuals will be paid a salary and will be housed at our location 10
  • 11. Community Assessment • During recruitment efforts, the recruitment officer will also be in charge of identifying suitable living arrangements for the CHWs, as well as storage facilities for supplies • Proper locations for secondary screenings will also be necessary during this time 11
  • 12. CHW Training • CHWs will be taught about SAM, along with the necessary protocols with which to identify children who have SAM – MUAC < 110mm – Bipedal edema • In addition, CHWs will be educated on other public health measures such as clean water and sanitation 12
  • 13. Promotion Team • While recruitment and education initiatives are underway, a promotion team will be enlisted. • The purpose of this team will be to begin to promote the large-scale secondary screening to come in the following weeks to evaluate children who meet SAM criteria 13
  • 14. Local Teams • Once adequately trained, CHWs will seek out community leaders and healers to form a local team of screeners and educators • CHWs will be in charge of educating these locals, predominately women and mothers, to screen for SAM and to educate on public health issues 14
  • 15. Mothers in the Community • After becoming proficient in methods of detecting and educating, these local teams will disperse into their respective neighborhoods and will begin teaching mothers there utilizing the Hearth Model • These mothers will then be capable of recognizing SAM and knowing what to do and where to go 15
  • 17. Education Intervention Flow Chart Complicated Referred 1⁰ and 2⁰ SAM Rapid screening Uncomplicated Weekly Weekly Supply SAM Checkup education and check for improvement Not SAM Not improved within 3 weeks Parents at home Referred screening prevention 17
  • 18. At Home Screening MUAC <110 mm Yes SAM: OR 2 Screening edema No MUAC Surveillance 18
  • 19. 2 Screening Non- Complicated SAM complicated 1: Grade 3 pitting edema OR 1: MUAC < 110 2: MUAC <110 & Grade 1/2 edema OR OR 3: MUAC <110 & one of the following: 2: MUAC 110 w/ •Anorexia Grade 1/2 edema •Lower Respiratory AND: Tract Infection •Appetite •Severe palmar pallor •Clinically well •High fever •Alert •Severe dehydration •Not alert 19
  • 20. 2 Screening – Non-complicated cases: • Weight assessment • Give weekly supply of prophylactic antibiotics, RUTF’s (purchased from local manufacturers), & food ration for family • Detailed instructional component • Set up weekly follow-up for monitoring 20
  • 22. Monitoring • Will consist of 4 procedures: – Weekly recorded measurements – Screening for potential complications – Deferment to MSF for treatment of complicated SAM – Providing the next week’s provisions • Will occur at all 4 centers in Arsi Nigele 5 days a week (with an estimated child load of 300 children/day) • If fewer designated days are desired by mothers, we will accommodate them 22
  • 23. Monitoring: Weekly Progress 1) Weight gain: WHO Standards of Weight Gain: 2) Pitting Edema: -reduction or disappearance 23
  • 24. Monitoring: Screening for Complications • For those that are failing to improve, determine the etiology: – Inappropriate administration – Non-compliance – Underlying Infection – Missed complication 24
  • 25. Reporting and Outcome Evaluation • Send out weekly progress reports to the Phil and Linda Bates Foundation, as well as local consensus agencies, UN, etc. – Weight changes – Presence and grade of edema – Complication rates • Outcome evaluation – DALYs – Mortality & morbidity rates 25
  • 27. Local RUTF Production • Use of locally grown crops to produce RUTF • Crop growth will occur concurrently with purchased RUTF treatment • Additional crops will be grown to fund RUTF components not immediately available 27
  • 28. Components of RUTF • Sugar and oil are made locally within the region • Peanuts are made in Addis Ababa • Soy production will soon begin locally via an Indian manufacturer Ruchi Soya ***Due to the high cost of milk, soy products will be substituted 28
  • 29. Local Production • Production specifics will reflect those outlined in Manary’s article in Food and Nutrition Bulletin • Quality control will be maintained based on the protocols outlined Manary. 2006. Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition. Food and Nutrition Bulletin, vol 27; 3. 29
  • 30. Collaboration Efforts • Doctors Without Borders: – Referral Clinic(s) • GAVI government partnerships: – Incentive for families to participate (receive food AND vaccinations) – Share resource costs • UNICEF/UN WFP: – Partnership for food distribution to families 30
  • 31. $1.0 million Budget $200,000 Salaries (Director, ADs, CHWs, Local Outreach Workers) $300,000 Treatment (RUTFs, supplemental medications/therapies, food for families) $200,000 Transportation, Housing, Rent, Medical supplies, MUACs, Other $300,000 Agriculture Sustainability measures (industrial mixers, seeds, etc) 31
  • 32. Benefits PHASE I: PHASE II: • Location • Cost effective • Replicable •Save lives •Education of women •Community investment PHASE III: PHASE IV: •Adequate monitoring • Sustainability •Preventative measures • Decreased incidence of SAM • Increased compliance 32
  • 33. Limitations PHASE I: PHASE II: • Lack of participation • Opportunity costs to parents referred to clinical facilities • Noncompliance to screening procedures • Underlying complications PHASE III: PHASE IV: • Accuracy of outcome data • RUTF Manufacturing: need to buy vitamin supplements • Long term follow up • Transport costs 33
  • 34. References • World Health Organization. Management of severe malnutrition: a manual for physicians and other senior health workers. Geneva, 1999. • RE Black, LH Allen, ZA Bhutta et al. and for the Maternal and Child Undernutrition Study Group, Maternal and child undernutrition: global and regional exposures and health consequences, Lancet 371 (2008), pp. 243–260. • Bhutta Z, Ahmed T, Black RE, Cousens S, Dewey K, Giugliani E, Haider BA, Kirkwood B, Morris SS, Sachdev HPS, Shekar M, Maternal and Child Undernutrition Study Group: What works? Interventions for maternal and child undernutrition and survival. Lancet 2008, 371:417-440. • Bahwere P, Binns P, Collins S, Dent N, Guerrero S, Hallam A, Khara T, Lee J, Mollison S, Myatt M, Saboyo M, Sadler K, Walsh A: Community Based Therapeutic Care. A Field Manual. Oxford, Valid International; 2006. • Prudhon C, Prinzo Z, Briend A, Daelmans B, Mason J. Proceedings of the WHO, UNICEF, and SCN Informal Consultation on Community-Based Management of Severe Malnutrition in Children. Food and Nutrition Bulletin 2006; 27(3):S99-S108. • Nutrition Working Group, Child Survival Collaborations and Resources Group (CORE), Positive Deviance / Hearth: A Resource Guide for Sustainably Rehabilitating Malnourished Children, Washington, D.C: December 2002. • Humanitarian Bulletin. UN Office for Coordination of Humanitarian Affairs. 18 May 2009. • http://www.doctorswithoutborders.org/news/article.cfm?id=2727 • http://www.gavialliance.org/resources/Ethiopia_GAVI_Alliance_country_fact_sheet_June_2008_ENG.pdf • http://www.unicef.org/infobycountry/files/ETHIOPIA_UNICEF_HAU_12_March_2009.pdf • World Health Organization. Management of the child with a serious infection or severe malnutrition: Guidelines for care at the first referral level in developing countries. 2000. Accessed February 19, 2010. http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.1.pdf • Collins, Steve, et Al., (2005). Key issues in the success of community-based management of sever malnutrition. Valid International Ltd. 34
  • 35. Appendix 35
  • 36. 36
  • 37. 37
  • 38. 38
  • 39. DALY’s: Disability Adjusted Life Years • Measures overall disease burden • Combines mortality and morbidity into one measurement • DALY = YLL +YLD – YLL: years of life lost • YLL = N * L N: # deaths L: Standard Life Expectancy • YLD = I * DW * L I: Incidence Cases DW: Disability Weight ( 0 = perfect health 1 = equivalent to Distribution Weights death -disease severity Wasting: 0.053 L: avg duration of case until remission or Stunting: 0.002 death Develop. Disability: 0.024 Cretinism (Iodine Deficiency): 0.804 Corneal Scar (Vit. A deficiency): 0.277 Severe Iron deficiency anemia : 0.090 Cognitive Impair.: 0.024 WHO & Global Burden of Disease 2004