1. RHEUMATOID ARTHRITIS
PRESENTED BY: MUHAMMAD TAHIR HABIB
EMAIL: MRTAHIRHABIB@GMAIL.COM
DEPARTMENT OF FOOD SCIENCE AND TECHNOLOGY
UNIVERSITY OF AGRICULTURE, MULTAN
Muhammad Tahir Habib
Founder & CEO,
TipRicks Inc.
www.tipricks.tk
Cell: +92 308 477 4257
Email: tipricks@gmail.com
2. Introduction
Chronic autoimmune disease
Causes joints to swell and can result pain, stiffness, and
progressive loss of function.
Affects pairs of joints (both hands, both feet, etc.)
Permanent joint damage
Cause deformity of the joints and loss of function.
Patients face difficulty performing activities of daily
living
3. Cont…
Usually begins in middle age
Disease ratio women to men is 3:1
Affect 1% of all population
Effect other parts including the skin, lungs and eyes
4. Causes
Cause is unknown
Common in people who smoke and in people who are above a healthy weight.
Possible causes include:
Genetics
Female Hormones
Viruses or bacteria
9. Effects
40% of people may develop other conditions or disease.
Patient likely to have
Chest Pain
Eyes
Dry Mouth
Difficult Breathing
Bumpy Skin
Weakness in the Knees
Uneven stance in ankles
12. Diet Management
No specific “diet”
Researcher identified some food
Citrus Fruits
source of Vitamin C
Whole grains
higher in nutrients and fiber
13. Cont.…
Peas and beans
great source of protein
contain antioxidants
rich in folic acid, magnesium, iron, zinc and potassium
Olive Oil
contains a compound called oleocanthal
acts like ibuprofen
14. Cont.…
Fruits and Vegetables
rich in antioxidants
packed with vitamins and minerals
lower C-reactive protein (CRP)
Pomegranates
Research is under way on POMx
helpes lowering inflammation
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Notes de l'éditeur
-Rheumatoid arthritis (RA) is a chronic autoimmune disease.
-It causes joints to swell and can result in pain, stiffness, and progressive loss of function.
-RA often affects pairs of joints (both hands, both feet, etc.) And can effect more than one joint including wrists and hands other joints can be affected such as shoulders, elbows, knees, feet, and ankles.
-The inflammation of RA can cause permanent damage to the joints.
-In severe cases, it can cause deformity of the joints and loss of function.
-RA usually begins in middle age (80% cases occur between 30 and 55 years), but can start at any age.
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-Rheumatoid arthritis can also affect other parts of the body other than the joints including the skin,
lungs and eyes. Many people have dry eyes and mouth (“sicca” symptoms or Sjogren’s syndrome)
associated with the arthritis.
No one knows exactly why some people develop rheumatoid arthritis.
It is more common in people who smoke and in people who are above a healthy weight.
Research has found that there are many possible causes, including:
Genetics People with family members who have RA may be more likely to get it
Hormones Female hormones may play a role in the disease
Viruses or bacteria RA may be related to viruses or bacteria that you come in contact with during your
life
The white blood cells move into the joint
they release chemicals called cytokines which attacked the lining of the joint called synovial membrane
thick tissue called pannus grows inside the joint
-Over time that tissue invades and destroys the cartilage and bone inside the joint.
-Inflammation causes fluid buildup in the joint making it swell. Eventually the damage makes it hard to move the joint.
Up to 40% of people with RA may develop other conditions during the course of their disease. While RA affects the joints, people with RA may also be more likely to have the following conditions:
Chest Pain
You may develop chest pain if your lungs get damaged from log term inflammation.
Dry Eyes
RA can cause extremely dry eyes, that can further cause eye infection.
Dry Mouth
Chronic dry mouth can make I hard to eat and swallow. It can also lead to other disease (like gum
disease) and mouth infection.
Difficulty Breathing
The inflammation of RA can spread to lungs making it hard to breathe. Patient can also experience
coughing.
Bumpy Skin
Hardened skin bumps called nodules may form on your arms especially around the elbows
Weakness in the Knees
RA can cause notable stiffness and swelling in your knees. The pain is usually worse in the morning and
after standing up.
Uneven stance in ankles
When RA effects your ankles you may notice that its more difficult to walk evenly. Standing for long
periods of time may also be very painful.
-Constitutional Symptoms (Constitutional symptoms refers to a group of symptoms that can affect many different systems of the body. Examples include weight loss, fevers, headache etc.)
-Malaise (a general feeling of discomfort, illness, or unease whose exact cause is difficult to identify.)
While there is no specific “diet” that people with rheumatoid arthritis (RA), should follow, researchers have identified certain foods that can help control inflammation.`
Citrus Fruits
Oranges, grapefruits, and limes are great sources of vitamin C, which leads to a strong immune system that can help hold off inflammatory diseases like RA.
Whole grains
Oats, whole wheat, brown rice, quinoa and other whole grains may lower levels of CRP and reduce the risk of heart disease, which is elevated in people with RA. Whole grains are higher in nutrients and fiber than refined grains.
Peas and beans
These legumes are a great source of protein, which is important for muscle health – and people with RA are prone to muscle loss. What’s more, peas and beans are practically fat free, contain antioxidants, and some are rich in folic acid, magnesium, iron, zinc and potassium, all known for their heart and immune system benefits.
Olive Oil
Use olive oil instead of other oils and fats. In addition to healthy monounsaturated fat, it contains a compound called oleocanthal (natural phenolic compound found in olive oil) that reduces inflammation and acts like ibuprofen in alleviating pain. But eat it in moderation; as with all oils, it’s a fat that can lead to weight gain.
Fruits and Vegetables
Fruits and vegetables are rich in antioxidants, which help stabilize molecules called free radicals that can trigger inflammation and damage cells. They’re also packed with vitamins and minerals the body needs and in polyphenols, all of which may help lower C-reactive protein (CRP), a marker of inflammation. To get the greatest health benefits, eat several types of fresh or frozen fruits each day, but watch out for sugar content in frozen options. Eat a colorful variety of veggies to get the most nutrients.
Pomegranates
Research is under way on a pomegranate extract called POMx (powerful blend of all-natural polyphenol antioxidants made from the very same pomegranates). It helped lower inflammation and lessen joint damage in mice, but it needs more testing in humans.
Onion
Onions are packed with beneficial antioxidants. They may also reduce inflammation, heart disease risk and LDL, or “bad” cholesterol. Try them sautéed, grilled or raw in salads, stir-fries, whole-wheat pasta dishes or sandwiches.