Best of 5 Bio-Technology Comapnies In India.pdf

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Bio-Tech
Upcoming Advances
in Bio-Tech Landscape
Vol. 05
Issue 05
2022
Leveraging Innovation to Provide the Best
Safety First
Five ways Businesses
can safeguard themselves
using Bio-Tech
Dr. Vinodkumar Patil,
Founder
Best of
5Bio
Technology
Companies
In India
DynaBiotech
Urja Bio System Pvt. Ltd
Ensuring the Sustainable
Future of Renewable Energy
SPECIAL PROFILE

THE VISTAS
OF EVOLUTION
Editor’s Note

hat do stone-washed jeans and in-house
Wconception tests all have one thing in common
with bread, cheese, and wine? They all are
precise examples of manipulating living organisms to
generate new products with new methods. This is an
innovation that biotechnology has enabled in the last few
decades.
Since the dawn of civilization, humans have been using
biotechnology to create new products. Just like the people
of Egypt who utilized yeasts to bake leavened cheese, the
people of China developed and arrayed agitation techniques
in brewing beverages; moreover, the Aztecs utilized
Spirulina algae to bake cakes.
Today—biotechnology is being used in various sectors like
agriculture, clinical applications, bioremediation, and
forensics—it is being a prominent player where DNA
sequencing is a customary practice. All these innovations
include genetic engineering, diagnostics, and assays,
reflecting the importance of synthetic biology in the up-to-
date biotechnological advancements.
The primary reason why biotechnology is spreading its
wings, is being looked at as the science of the future and is
one of the leading industries in the dynamic era of
advancements—Genetic manipulation—the answer is quite
simple.
Biotechnology is becoming a major engine for modern
competitiveness in the twenty-first century. Emerging
policymakers are looking at it as a key technology towards
expanding the horizons eventually. Biotechnology is
undoubtedly a paradigmatic knowledge-based economic
activity, a knowledge-driven sector consisting of working
knowledge in creating values and decoding genomics.
For the eminent companies in this sector, there is no
arguing that the biotech industry has entered a new era with
perpetual advancements. On the brighter side, the biotech
market is now more informed and demands proof of
effectiveness in the form of improved outcomes along with
scientific developments.
The companies in this transcending niche are now among
the most innovative and crucial monetary drivers in the
contemporary industry economical sector. Comprehending
these vital fundamentals, Insights Success embraces the
journey of a few of the prominent companies in its latest
edition, 'Best of 5 Bio-Technology Companies In India,'
that are empowering perpetual innovations and augmenting
the modern industry through impeccable services.
Flip through the pages and explore the horizons of
advancements, Have a delightful read!
Abhishek Joshi
Deputy Editor
abhishek.joshi@insightssuccess.com

C o v e r S t o r y
DynaBiotech

A r t i c l e s
14
32
C O N T E N T
22 Bio-Tech
Upcoming Advances
in Bio-Tech Landscape
Safety First
Five ways Businesses
can safeguard themselves
using Bio-Tech
18
26
Leading a New Global Era of Biotechnology
Nirav Biosolutions
Private Limited
URJA BIO SYSTEM PVT LTD
Ensuring the Sustainable Future of Renewable Energy
S p e c i a l P r o ﬁ l e
P r o ﬁ l e s

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Featuring Brief
Company Name
Vinodkumar Patil,
Founder
Dyna Biotech oﬀers expertise in Automation Solutions with
manufacturing facilities in four continents and is at the forefront
of manufacturing, validation, installation and services for a wide
range of Biotechnology and Biopharma equipments.
Dyna Biotech
Amol Shah,
Managing Director
M J Biopharm is a growing multi-national conglomerate with a
presence in Pharmaceuticals, Biotechnological, Flavours,
Fragrances, Agro Chemicals and Speciality Chemicals Industries.
M J Biopharm
Pvt. Ltd.
Mrs Vaishali Sharma,
CEO
Nirav BioSolutions Pvt. Ltd. is a Life Science company and has
signed a collaboration with the Institute of Professional
Education and Research to develop a programme in pharmacy for
aspiring students.
Nirav Biosolutions
Pvt. Ltd.
Mr Gajanan Patil,
Managing Director
Urja Bio System Pvt. Ltd. specializes in designing and executing
turnkey projects in solid waste management and conversion of solid
waste into energy (in the form of electricity and heat) and organic
fertilizer from the residue.
Urja Bio System
Pvt. Ltd.
Best of
5Bio
Technology
Companies
In India

“
Dyna Biotech’s
omnipotent strategy
supports advancement
in all areas of development.”
DynaBiotech

C
O
V
E
R
S
T
O
R
Y
Dr. Vinodkumar Patil,
Founder

the booming bio-equipment manufacturing market.
Dyna Biotech is now the industry leader in the
production, installation, validation, automation, and
support of a wide range of biopharmaceutical and
biotechnology equipment, with a broad, configurable
product line. With innovation, customisation, and
great customer service it has ushered in a paradigm
shift in the biopharmaceutical and biotechnology
sectors in India and beyond.
The Visionary Leader
Dr. Vinodkumar Patil is a multitasker with experience
in microbiology as well as engineering. He is also
well-versed in biotechnology as a result of his
diversified professional experience. He was really
enthusiastic about starting his own manufacturing
business. He was motivated to create Dyna Biotech
after working with top-tier biotech and pharmaceutical
companies throughout the world for more than two
decades.
Dr. Vinodkumar’s goal was to pave the road for young
aspirants and provide them with job chances. He
wants to transform India's biotechnology sector and
give it international respect.
Providing the Best
Dyna Biotech has been able to get requests from
overseas at a consistent pace, has built a new setup,
and has designed new products for a variety of
industries throughout the years. It has developed
business in countries such as Turkey, Germany,
Taiwan, South Korea, Bangladesh, and others, where
they provide a wide range of fermenter, bioreactor,
and pressure vessel equipment. Dyna Biotech has
established an international sales, marketing, and
service office in Bangkok, Thailand, as well as a Pan
India service office in Hyderabad, to suit the demands
of the worldwide market for biotech equipment.
Dyna Biotech has established itself as a source of
high-quality technologies and premium equipment at a
reasonable price. It is widening horizons in the health
care and veterinary sectors by building the best
product variety, which is having a significant and good
impact on APIs, vaccines, pharmaceutical products,
drinks, food, and dairy landscapes, among others.
Dyna Biotech uses a client-specific methodology to
monitor every stage of design, manufacture,
installation, commissioning, automation, integration,
and validation. These specific customer requirements
Every day, biopharmaceuticals are transforming
medicine and saving the lives of thousands of
people. Biopharmaceuticals are among the
most impressive achievements of modern science.
These medications are progressively being employed
in almost every realm of the medical sector, and they
have shown to be one of the most successful clinical
therapy methods for a variety of illnesses, including
cancer and metabolic disorders.
Currently, there are noteworthy developments in the
biopharmaceutical fields. While new
biopharmaceuticals and drug development methods
are found and developed, the advancement and
development of biotechnology is the driving force
behind this progress. Biopharmaceutical innovation,
on the other hand, comes up against multiple hurdles
from various directions in order to invent and market
newly produced biodrugs.
This did not, however, deter biopharmaceutical
companies, researchers in related fields, and
pharmacists from continuing their noble work and
innovating even further, because biopharmaceutics is
one of the most important approaches to shaping and
improving healthcare, extending healthy productive
longevity, and reducing the spread of severe diseases.
Furthermore, biopharmaceutical innovation is a
critical component of development and effective
leadership in expanding industrial output; such
innovation is a driver of economic growth and assures
the country’s competitiveness in the global market.
And a company keeping up with every trend in this
industry is Dyna Biotech. With Dr. Vinodkumar
Patil, Founder, leading the way of Dyna, it is
reaching uncharted heights of success.
The Great Beginnings
Dr. Vinodkumar Patil founded the company in Pune in
April 2013. During his 27 years of engagement with
global Pharma giants such as Sartorius, B. Braun
Biotech, Lupin Ltd, Serum Institute, and Shantha
Biotech as a microbiologist, Dr. Patil obtained
significant insights into the industry’s needs.
Dr. Patil’s education, technical skills, and
entrepreneurial drive formed the groundwork for
Dyna Biotech, a dynamic company. With bioreactors
and fermenters, it began as a modest attempt to join
Best of 5 Bio Technology Companies In India

on shifting market trends and promptly
responds to them.
Dyna Biotech’s ingenuity and
excellence have won awards all
around the world. Dr.
Vinodkumar Patil has
received numerous
awards over the
are taken into account when developing progressive
customised solutions. The firm has established itself as
the market leader in the speciality of highly-
specialised bioreactor production and automated
customised fermenters.
The Gems of Dyna
The firm is continually attempting to create and
maintain a perfect balance between the functionality
and cost of its goods while maintaining high
international quality standards. The influence of its
management policies and practises, as well as
excellent execution and deft innovation and resource
management, has been lauded and rewarded with
great success.
Dyna Biotech has a skilled team of over 300
people, including 150 engineers, biotech,
pharmaceutical, and microbiology
specialists. This dedicated group
supports and directs a variety of
operations aimed at improving
product quality, effectiveness,
efficiency, and estimate. It
also keeps a close eye

years, including the Doctor of Philosophy (Science
and Biotechnology), Business Excellence Award,
Company of the Year Award 2020, Adarsh Udyojag
Award, Industry Young Academic Entrepreneur
Award, Certificate of Excellence from CEO Magazine,
and so on.
Dyna Biotech has risen to prominence in society by
creating both direct and indirect job possibilities. It
sees itself as an important part of society, hence
corporate social responsibility is crucial. Dyna
Biotech has been involved in programmes such as
mass tree planting on desolate lands, roadsides,
railway stations, and public common places over the
past few years. It is also linked to charitable initiatives
for the State Police Department and the
underprivileged. The biggest reward for Dyna Biotech
is the opportunity to serve the country.
Future Endeavours
Dyna Biotech has a large and devoted customer base
in Germany, the United States, Thailand, South Korea,
Bangladesh, Taiwan, and Turkey. The company’s
long-term strategy is to grow its international market
network. The firm has opened international sales and
service offices in Bangkok, Thailand and London, UK
which run by a team of highly-skilled people, solely
for this purpose.
Dyna Biotech is certain that supplying the worldwide
market is the best way to generate more foreign cash
for the country’s growth. As a result, the organisation
is dedicated to the growth and development of both
the international and national communities.

Mr Gajanan Rustumrao Pa l,
Managing Director
URJA BIO SYSTEM PVT LTD
Ensuring the Sustainable Future of Renewable Energy
“
By converting
wet biodegradable
waste into Biogas
and Biogas to power
and Biogas to
Bio-CNG,
Urja Bio System
helping Mother
Earth to reduce
the greenhouse
gas emission and
produce Value-added
Manure to improve
soil fertility.
“
“
“
14 | May 2022 | www.insightssuccess.in

“
“Urja Bio System
has already reached
in 18 states of India
and in the countries
like Zambia, Tanzania,
Gambia and also going
to expand in Bangladesh
and Sri Lanka as well.
“
“
Best of 5 Biotechnology Companies In India

W
e cannot let health go out
of our focus. A
community of healthy
individuals makes a healthy society.
And a healthy society is the
prerequisite of a healthy nation.
The nation with a mission to become a
‘Vishwa-Guru’ must make sure that
each of its citizens remains healthy and
leads a healthful lifestyle. That is the
core vision it must never lose focus of.
This vision promulgates the philosophy
of supporting human life in a
responsible way. A healthy life leads to
a happy and prosperous lifestyle. A
true visionary observes that the future
is nothing but a manifestation of our
constant efforts to improve it in the
present time.
MJ Group was born from the above-
stated philosophy of one such
visionary Founder – Mr Jashubhai
Shah. He predicted the positive shift in
the economic power of developing
nations and the need for new age
medicines for lifestyle diseases, such
as diabetes.
In our search of the Best
Biotechnology companies in India,
fortunately, we met with Mr. Amol
Shah, Managing Director of M.J.
Biopharm Pvt Ltd., a pharma and
biotech arm of the three-decades-old
and growing multinational
conglomerate.
A Trust Built with Time
Mr Amol Shah is also managing the
entire MJ group, which has nurtured
the rich heritage and philosophy of its
founder, prioritizing people's well-
being above everything else.
He revealed that the group started its
biotech operations by collaborating
with Eli-Lilly of USA and became the
first in the industry to manufacture
recombinant human insulin
formulations in India.
He further highlights the company’s
continued independent journey in
diabetes care. He also points out their
significant contribution by setting up a
fully dedicated biotech facility to
manufacture insulin drug substances
through the bacterial fermentation
route.
Moving Forward Together
Congruent with the vision of the
founder of the company, MJ started
with the challenge of registering the
company with various institutions in
India. The purpose was to provide
high-quality domestic insulin at an
economical price. Over a period of
three years, the company has emerged
as one of the main suppliers to several
institutions around the country.
Mr Shah is very proud of the
company’s achievement of becoming a
preferred supplier of Insulin to the
prestigious ‘Pradhan Mantri Bharatiya
Janaushadhi Pariyojna’ (PMBJP)
scheme. The scheme ensured the
availability of medicines at prices
lower than MRP to the common Indian
citizens.
MJ continues to provide Insulin at
preferred prices to the various
institution. It is to fulfil the company’s
vision, of making India self-reliant in
meeting the requirement of Insulin, for
the diabetic population of India.
Overcoming the Turbulent Times
According to Mr Shah, the government
of India had taken a bold step of
declaring a nationwide lockdown to
arrest the spread of the COVID-19
pandemic. And he further opines that
the lockdown, whilst essential to
ensure the larger safety of the Indian
citizen, severely restricted the mobility
of individuals.

However, he says “Pharmaceutical
manufacturing, logistics and associated
supply chain were exempted from this
lockdown. Biotech and pharma
companies have strongly rallied, to
ensure smooth delivery of the essential
products during the lockdown.” He is
satisﬁed that they have demonstrated
the innovative and creative side of the
industry, by being the earlier ones to
develop the crucial vaccine to deal
with the COVID-19 pandemic.
Best of 5 Bio-Technology Companies In India

He strongly believes that the current
pandemic has shown resilience and
capabilities of the pharmaceutical
industry in India, to weather any storm,
and the industry has come out with
flying colours.
Unmatched efficiency
Today, MJ Biopharm is one of the
largest manufacturers of human Insulin
for supplies in India and Mr Shah is
aware that millions of patients are
counting on the company to provide
them with this life saving product. “We
had made a promise to our customers
and doctors and now it was up to us, to
ensure that we do not break this
promise.” Mr Shah says
compassionately.
Telling about their strict measures
taken during the pandemic, Mr Shah
states that they took necessary
precautions to ensure a safe and
hygienic work environment, including
making special transport arrangements
to ensure safe distancing in transit for
all our employees reporting to work.
They also arranged for vaccination of
all employees of the company to
ensure their safety, whilst they were
daily exposing themselves to the
dangers of COVID-19.
Further, along with the regular
sanitisation program, adequate stocks
were kept of hand sanitisers, face
masks and gloves, as well as proper
food arrangement at the factory
premise, etc. to ensure the well-being
of MJ group’s employees.
Embracing Tech-novation
As per Mr Shah, Artificial Intelligence
(AI), Machine Learning (ML), and
Deep Learning are taking the
healthcare industry by storm. He
knows that some healthcare and
technology innovators are
collaborating and trying to change the
current reality by experimenting with
these concepts.
He is also happy that these concepts
are turning into reality and pointing the
way for the future growth of the
industry. He believes that they are the
practical tools that can help companies
improve the standard of care, identify
the risks earlier in many cases and
improve the overall quality of life.
“The best metaphor I found describing
AI in healthcare in one of the articles,
that said, that the question is not ‘if’
but ‘when’ AI will revolutionize the
healthcare,” he remarks.
He provides real-life examples, like
companies such as Moderna and
BioNTech that have revolutionised
vaccine development by developing
mRNA technology. And he hopes that
based on this extraordinary impact,
improvements to the healthcare system
can have for so many people and its
potential to save lives and money.
He further mentions that healthcare has
become a key industry for investment
and efforts for AI and machine
learning. He informs that several start-
ups and smaller organisations have
begun their efforts to create tools to aid
healthcare.
Building a Better Future
The last year has been challenging to
the Indian economy due to the ongoing
pandemic and MJ group was also
affected in some ways. However, it has
made all the efforts to ensure that it
retains its strong position in the market
in the years to come. And to counter
such future challenges, the company
has developed end-to-end capabilities
ranging from biopharmaceutical
process development to drug substance
and drug product manufacturing on a
large scale and continues to invest in
this avenue.
Company’s expansion project in Pune
is targeted for completion in 2022,
resulting in additional capacities with a
focus to enter regulated markets and
bring economies of scale. The state-of-
the-art manufacturing facility will have
a capacity of 25 million vials and will
be EUGMP compliant.
The company has also made significant
investments in R&D and regulatory
practices, to create a robust product
pipeline.
MJ Group has a healthy pool of PhD’s
now heading its many departments.
With new products under development,
it is also working on the model of Tech
Transfer License to be the early ones
for offering new products. It is further
partnering with companies developing
software solutions to enhance the life
of diabetic patients.
Finally, on the marketing front, Mr.
Shah says that their focus area is “To
continue collaboration with strong
marketing partners across territories for
our entire product range and invest in
novel delivery systems, to be in line
with the changes happening around the
globe.”

Upcoming
Advances in
Bio-Tech
Landscape
The technological developments have helped
numerous sectors of the industry in achieving
higher levels of purpose, quality, speed, experience,
safety, cost, and satisfaction. Similarly, technological
progress in the field of healthcare and life sciences has
reached different milestones in numerous dimensions.
The developments have aided in identifying, analysing, and
controlling newer challenges in disease management and
eradication, improving health, better handling and
managing numerous ailments towards a healthy life.
The progress made in biosciences has been far-reaching and
taken medical functioning from a higher perspective.
Identifying the various categories of developments, the
researchers are contributing to is interesting. Some of the
promising developments are elaborated as follows
• COVID 19 Testing
Recently, Jeremy Edwards, director of the Computational
Genomics and Technology (CGaT) Laboratory at The
University of New Mexico, and his other colleagues
developed a chip that makes genome sequencing for viruses
like COVID-19 much easier and faster.
Eventually, they were able to identify 95 percent of each
sample's genome with an efficiency of more than 99.9%.
Edwards, who is a professor in the UNM Department of
Chemistry and Chemical Biology, even stated that this new
chip would allow for faster and more accurate tracing of
COVID and other viruses, including new variants.
• Gene Manipulation
Researchers have identified that the specific human
endogenous retroviruses or HERVs, which are found
throughout our genome, are activated and severely impair
brain development. Biotechnology developments have
helped in a better understanding of the HERV process.
Researchers produced human endogenous retroviruses in
human stem cells and created neurons using CRISPR
technology. These viral components have triggered specific
genes linked to brain development, including traditional
development factors.
• Gene Sequencing
Genome Sequencing that determines the whole set of
genetic material has developed phenomenally. The
researchers sequenced 3219 patients where 750 genes
revealed to have dangerous mutations, with 17 new disease
genes were uncovered. Patients with hereditary metabolic
illnesses, uncommon epilepsies, and primary
immunological deficiencies have benefited from
personalized treatment in some situations.
Bio-Tech

Karolinska Institutet and Karolinska University Hospital,
this technique has also led to the discovery of other
previously undiscovered disease genes, opening new
avenues for further investigation of pathogenic pathways.
• Vaccine Development
Many synthetic biologists have identified a new approach to
increase the manufacturing yields of protein-based
vaccinations, perhaps increasing access to life-saving
medicines. Recently, a significant contribution was made to
the development of COVID-19 vaccines by Dr Katalin
Karikó. She showed that altering nucleosides, which are the
building blocks of messenger RNA (mRNA), makes it safe
for use in vaccines against pathogenic agents.
With her discoveries on the stabilizing impact of altering
nucleosides, scientists constructed mRNA vaccines for
COVID-19, developed by Pfizer and Moderna. In clinical
testing, the vaccines showed 94 percent effectiveness in
avoiding symptomatic sickness and are used across the
United States to help stop the pandemic.
• Synthetic DNA
Professor Kurt Gothelf's group has developed a distinct way
to produce the volatile building blocks instantly before they
are to be used, thereby making DNA production more
efficient. The DNA sequences produced need an automated
method for chemical production. They created an operative
technology that enables the manufacturing of
phosphoramidites to be mechanized and integrated into the
DNA synthesis system, eliminating the need for manual
synthesis.
Nucleosides are flushed via a resin in the method of
creating phosphoramidites, which could be fully
incorporated into an automated process in the DNA
synthesis equipment. The resin guarantees that the
nucleosides are quickly phosphorylated, resulting in the
conversion of nucleosides to phosphoramidites, resulting in
DNA synthesis.
• Biosensors
To improve and speed up the COVID-19 testing, KAUST
scientists merged state-of-the-art bioelectronics equipment,
materials science engineering, and synthetic biology protein
design. This new biosensor technology can be successful in
delivering very precise results. A combination of
electrochemical biosensors with designed protein structures,
this diagnostic allows clinicians to detect virus bits rapidly
and precisely, something that was previously only
achievable with slower genetic procedures.
The complete system may operate on unprocessed blood at
the point of care, eliminating the need for time-consuming
sample collection. Primarily, human saliva and blood
samples treated with portions of protein from the
coronaviruses that cause MERS and COVID-19 were used
to fine-tune the test.
• 4D Printing and Tissue Engineering
Researcher Eben Alsberg formed new 4D materials
structured on gelatin-like hydrogels that alternate shape in
reaction to water and are cell-compatible and recyclable,
making them ideal choices for enhanced tissue engineering.
The hydrogels may also maintain very high cell densities,
allowing for a dense seeding of cells.
In addition, they also discovered that the system could be
calibrated to control the time and degree of the shape
alteration. The researchers implanted bone marrow stem
cells at a very high density in the hydrogel without
destroying them is significant progress in bioengineering.
Hydrogel's 4D bioprinting helps to form novel
configurations for more complex 4D constructions.
Creating a World of Possibilities
The technological developments in the numerous
biosciences sectors have aided the researchers in reaching
impressive benchmarks in conformity, analysis, and control
over the progress in medical research.
All the dimensions of internal weakness, possible external
causes, and individual vulnerability due to gene research
have reached an important milestone in numerous disease
prevention, recovery sequences coupled with medication,
and the creation of suitable growth environments. It is an
excellent sign of the progress of medical research, which
can contribute to creating a healthy, stronger, and agile
global society.
-Kedar Borgaonkar

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We help our
customers accelerate
life sciences research,
solve complex
challenges, improve
success, and increase
lab productivity.
Mrs Vaishali Sharma,
CEO

Leading a New Global Era of Biotechnology
Nirav Biosolutions
Private Limited
In the modern era, biotechnology has become the
foundation of global healthcare. Although prior to the
pandemic, the industry was moving at a constant pace-
thriving to keep up with the expectations. However, new
diseases and viruses were becoming regular, while only a
handful of people with scientific insights and interest were
willing to invest in the R&D of the healthcare and life
sciences.
That was also in mostly foreign countries and not in India.
These foreign companies would establish their regional
office in the country. Still, they would struggle to get
precise professional talent and students keen on taking up
medical R&D as their future career. All this happened when
everybody understood that R&D is the backbone of the
entire life science, healthcare, and biotechnology industry.
While working at two giant pharmaceutical companies,
initially as a Professional Service Officer at Pfizer and as a
Regional Manager of the west zone at Millipore, Pravin
Sharma observed this for almost eight years before being
ready to provide a solution for sure in the form of Nirav
Biosolutions Pvt Ltd, a Life Science company
incorporated in 2012. Soon, his wife, Mrs Vaishali
Sharma, joined him and the company as a CEO.
A Purposeful Innovation
Vaishali shares, “Incorporated in March 2012, we have
completed ten years of serving life science. We help our
customers accelerate life sciences research, solve complex
challenges, improve success, and increase lab
productivity. Through our premier, we offer an unmatched
combination of innovative technologies, purchasing
convenience and comprehensive services. We provide
scientists and engineers with best-in-class lab materials,
technologies and services.”
The founders clearly envision adding value to its esteemed
clients in Life Science Research. Strategically every
initiative was driven with a clear thought to bridge gaps and
provide a solution to researchers.
Initially, Nirav started as a biotech trading company with a
small team of technically competent people who could
understand applications in life science and provide
appropriate solutions.
Vaishali adds, “Within one year of inception, we found
ourselves a favourite among Biotech Product Manufacturers
who believed in our technical capabilities. We have the
privilege of working with some of the best brands in the
industry like Thermo Fisher Scientific, Invitrogen, BD
Bioscience, and Pall Lifesciences in the early phase of our
business.”
Turnaround and Turnover
To begin with, Nirav Biosolutions worked for customers in
the peripheries of Pune. Still, soon it was given an
opportunity to work with some elite customers in Pune like
CSIR-NCL, ICMR-NIV and NCCS among the central
government institutes and Lupin Limited, Gennova
Biopharmaceuticals and Emcure among the Pharma sectors.
Although it grew at a decent pace in the initial years, it was
not taking up big projects because of the financial
limitations of the organization. The first big project it took
up was in 2016, when it set up a functional Genomics Lab
at Chitale Dairy for their Buffalo breading program.
Best of 5 Bio-Technology Companies In India

The value of the project was 25% of Nirav's annual
turnover then.
Vaishali puts, “This project was a turnaround in our
thought process, and handling such big projects became a
routine activity for us.”
A Strategic Leap of Invention
By 2017 Nirav Biosolutions was ready to take a second leap
in terms of starting up a wet lab with the name Institute of
Applied Biology Research and Development (IABRD).
This lab has three primary objectives.
· To train master's students who wish to pursue a
career in R&D or QC in Biopharma and Pharma
Drug discovery, we wanted to do something for the
young generation because students don't have the
practical experience they need to get a job.
Vaishali adds, "We started the lab with the purpose
in mind of contributing toward better
employability."
· To support the research activities of Universities
and Academic institutes to work in the Applied
side of Biology.
· To provide a contract research lab which works on
Invitro studies at the cellular and molecular level
for new drug targets by the Biopharma/Pharma
companies and International CROs.
Fighting From the Front
Vaishali remembers, “Our real metal was tested during the
recent COVID-19 pandemic, where within complete
lockdown and unavailability of any commercially
approved testing kit.”
ICMR-NIV was at the epicentre of testing COVID samples
ﬂowing across the country. This was the most
challenging/demanding/emotional time of my life with
small kids and old in-laws at home, and no team member
was available. Vaishali states, “Fortunately, we – Mr Pravin
Sharma, my husband (also my business partner), and I had
to arrange the required raw material for manufacturing
COVID-19 testing kits with no logistic support.”
They travelled from the airport to the airport of
Bangalore, Pune Mumbai, with the thought process of
contributing towards the pandemic. It was the most
challenging time on the people, product availability, and
ﬁnancial sides. They worked 24×7 to support NIV. They

had to handle five times their turnover in one year, and they
clocked their first 100 Cr plus turnover that year.
However, Vaishali says proudly, “Rather than the turnover,
what was more satisfying was that we could serve the
nation when it was most needed. We are thankful to ICMR-
NIV and our principal client Thermo Fisher Scientific for
trusting in us.”
Discipline, Integrity and Positivity
Recently Nirav Biosolutions celebrated its 10th anniversary
in a new office space. Vaishali feels, "With a humble
beginning from a 330 Sq. ft office to a 3000 sq. ft. it is a
fulfilling journey." Even for IABRD, the new lab is
designed to be GLP compliant; this setup needs to work in
the drug discovery domain offering its services to Pharma
and Biopharma customers looking for discovery service
partners. Also, it will give students the experience of
training in a GLP-compliant lab.
Vaishali reveals, “Our Vision is to be a leading Solution
Provider in the life science industry for the betterment of
the Planet. As per our mission statement, we plan to take
the brand globally.”
With the Government initiative of Start-up and Make in
India, many Biotech startups are coming up. And with its
strengths being Marketing and Sales, Nirav Biosolutions
would like to take these brands to the international market.
"We have already started building capabilities around this
and are associated with many start-ups," says Vaishali.
Ritualistic Continuous Improvement
According to Vaishali, from the business perspective,
COVID-19 has made the world realise the promise that
Biotechnology holds, whether diagnostics or vaccines.
Secondly, it has made the Biotech Industry and
International Regulatory Authorities realise that they were
really moving at a very sluggish pace. They have the
capability of developing health care solutions at a much
faster rate.
The coming years will be for therapeutic antibodies,
vaccines, POC (point of care) solutions, molecular
diagnostics and Biosimilar.
Vaishali states, “A lot of basic research has happened in our
country over a few decades, and there are many aspiring
scientists who are coming up with their innovations in
healthcare with the support of the Government initiative
under BIRAC.” This is definitely going to boost the
industry.
Putting Down the Pandemic
About their pandemic experience and overcoming it,
Vaishali says, “During the pandemic, we had to be on the
front foot as we were the only leading suppliers to ICMR,
NIV, which was the epicentre of all the diagnostics during
the first wave when no kits were available.
As a policy, we provide opportunities to freshers from rural
parts. Post Lockdown announcement, our team had to be
mobilized to their hometown as no PGs were working.”
Most of the activity involved physical involvement in
arranging COVID testing reagents and delivering them to
ICMR-NIV; Nirav Biosolutions had to operate with
logistics support.
“However, teams were kept engaged in online training and
motivational talks from our side. We also kept them updated
about what was happening at the ground level,” reveals
Vaishali.
Value Adding Tech-Knowledge
Vaishali's opinion on biotech companies' need to align their
offerings with technologies like AI and ML, especially
when catering to the ever-evolving healthcare needs, is
cautiously optimistic. She says that having AI and ML in
the Biotech manufacturing process can bring in a lot of
automation and reduce error, thereby improving
productivity.
It is a personal belief that the same should not be applied in
diagnostics and treatment because it can never replace
clinical findings. Also, AI and ML will play a very limiting
role in the Research and Development of new therapies as
biological systems are complex and do not function like a
machine.
However, AI and ML can assist in both healthcare and R&D
to capture data, reproduce it for future reference, and
provide some analytics which can guide Clinicians and
Scientists to take decisions, but it cannot become SOP.

Encouraging Individual Initiatives
As an established industry leader, Vaishali's advice to
budding entrepreneurs and enthusiasts aspiring to venture
into the healthcare services industry is precise. As per her
experience, healthcare needs will be ever-increasing with
the population. Also, the preventive health check is
increasing with growing healthcare awareness and
insurance support. Lastly, post-pandemic Biotechnology
will proliferate in areas like immunisation, therapeutic
antibodies, biosimilar and POC devices. So, all budding
entrepreneurs should be focusing on this area.
The other central area where Biotechnology can serve is in
the sustainability of resources on the planet for the survival
of life on the earth. So, Biofuel, Biofertilizers, and
Livestock Management are a few other areas to focus on. “I
recommend doing a personal and industry SWOT analysis
before venturing into the industry,” suggest Vaishali.
Building Enduring Relationships
Vaishali's vision of further strengthening Nirav
Biosolutions' stronghold in 2022 and beyond is meticulous.
She says, “By 2027 we,
· Intend to Develop bio clusters in rural India
· Reach PAN India
· 20% Revenue from Exports
· Contributing to drug discovery and clinical
research area
· Establish a Service Organization to Serve the
Customers Better
· Build and Start Facilities for Manufacturing.”
So, the year 2022 would be the foundation year for Nirav's
next five years' plans. It is infusing experienced team
members and doubling the team size. It has already
increased its infrastructure and built up a GLP-compliant
lab.
Vaishali says, “We are working on setting up systems and
processes like CRM and ERP on the cloud. We are
collaborating with new principals and OEM
manufacturers to reach out to at least three states by the
end of the financial year 2022.
For this, we are looking for an association with some
business with whom we can establish synergy and work
together.”
Expanding the Vision of Vishwaguru
Nirav Biosolutions is working in rural areas, taking
seminars and providing hands-on training on advanced
technologies to students because Vaishali and the team
Nirav believes in providing equal opportunities to all.
The biotechnology industry in India is going to grow at a
supersonic speed. For that, the workforce will be needed.
“we want to increase the employability of students from the
rural areas. It is also our dream to engage, encourage and
enable 25000 biologists by giving them an experience of
advanced applied biological research by 2025, helping
them reach their full potential,” says Vaishali.
Finally, she concludes, “Our present and future purpose is
to enrich and accelerate research in Applied Biology for
the betterment of mankind through high-quality scientific
tools, expertise and experience of developing innovative
solutions.”

Five Ways
Businessescan
safeguard
themselves
using
Bio-Tech
Biotechnology is an amazing science which has been used
for thousands of years in its applications in agriculture, food
preparation, food preservation, creating of medicines,
beautification, decoration and many more applications. It is
basically the understanding of basic bio elements in various
forms that, when combined with other substances, can form
useful combinations for multiple usages.
The tasty pickle in our kitchen is preserved easily for
months together with the use of table salt and oil, which act
as natural preservatives making the pickle last for many
months.
Here are some simple and feasible tips on using
biotechnology to safeguard our businesses and focus on the
main work.
• Natural Pesticides
As we talk about the problem of numerous pests in insects,
rodents, birds and even animals, avoid jumping on chemical
pesticides with toxic elements. There are multiple organic
elements from nature which are effective repellent
properties. Plants like Neem, and Eucalyptus oil have
medicinal properties which repel insects. Burning bay
leaves can keep mosquitoes at bay.
Onion and Garlic spray is an effective pesticide that can be
sprayed on vegetable plants, fruit trees and flowering plants
to ward off mealy bugs, ants, and moths.
Rats can be destructive in every form by damaging
important documents, electrical wires, essential wooden
tools, and accessories. Simple use of Peppermint oil, Garlic

Safety First

bulb, onion slices, hot pepper flakes, and ammonia spray
can be used to ward off the rats.
Planting Bougainvillea flowering plants on the farm's
boundary can protect the planted fruits and flowering plants
from the thorns and bitter taste of the leaves.
• Use of Organic Consumables
Organizations should choose to use natural and organic
consumables to be used in their premises for various
applications of floor cleaners (salt and neem), soaps,
handwash, room fresheners and storage accessories. The
first aid kit should have natural healing agents like Aloe
vera gel, turmeric powder, clove oil, coconut oil and
Thymol seeds.
• Organic Kitchens
The corporate company kitchens to implement an organic
approach towards their functioning. Menus to include fresh
vegetables, salads, fruits, nuts, and beans. Healthy
beverages include green teas, Black coffee, and
Mint/Clove/Lemongrass teas. Fresh juices of different
fruits, lemon, ginger, and Indian gooseberry, to be provided.
Companies should ensure that employees get fresh, clean,
nutritious, organic food for a safe and healthy lifestyle.
The natural disposal of dry and wet waste creates organic
fertilizers like Compost or earthworm fertilizers.
• Healthy Practices, Eco-friendly Initiatives
People management activities should include Yoga, Zumba,
use of natural commutes like bicycles, staircases, etc., to
help develop good healthy habits for employees.
The organizations should encourage the activities of tree
plantations, organic farming, planning initiatives to
conserve and build our organic ecosystem, simple cooking
without fire, and many more.
• Building Energy Efficient Buildings
Companies have identified the importance of natural ways
of functioning and are adopting to develop natural energy
efficient premises. Use solar panels for PV power
generation and solar panels to heat water in company
kitchens.
The structure is planned smartly with the correct provision
for ventilation, light management, and heat control during
the daytime. Vertical gardening with the systematic use of
creeper plants and potted bushes has helped convert modern
business houses into smart ecosystems. The roofing
solutions too have natural elements to support light and
allow plenty of ventilation through the tilted glass windows
and façade structures.
The parking area can be transformed into natural green
parking by smartly horizontally planting bushes and
creepers to cover the designated area, creating a remarkable
share for the vehicles.
Green Shield for Dynamic Future
We are all a part of this nature. However, we live. Still, the
nature has a governing role in our life and work. It would
be simple to understand its importance and include the
organic way of life in every sphere. As the world braces
together to fight climate change, we can transform the
efforts through effective, lasting, and simple organic and
natural practices.
Many countries, including Japan, have implemented the
natural means in various aspects of their lives. It is time we
should wake up and make these slight changes to contribute
towards a healthy and sustainable future. We owe this
planet to our future generations, so let us take responsible
steps towards building an organic world of harmony with
mother nature.
-Kedar Borgaonkar

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