1. Phthalate

2. Phthalates
•Mainly used as plasticizers
added to plastics.
•Human-made chemicals
used in the manufacture of
household and industrial
products such as children's
toys, infant-care and
personal-care products,
cosmetics, garden hoses,
raincoats, adhesives and
lubricants.

3. Who is at Risk?
• Everyone!
• Mainly infants and
toddlers due to their
mouthing behavior with
products containing
phthalates

4. Health Effects:
Immediate Health Effects
• If SWALLOWED, phthalates is Slightly
Toxic
• If ABSORBED THROUGH SKIN,
phthalates is Moderately Toxic
• If INHALED (SNIFFED OR BREATHED
IN), phthalates is Slightly Toxic
Long-term or Delayed Health
Effects
• This chemical is likely to cause cancer.
• Allergen
• Suspected Endocrine Disruptor = May
interfere with, mimic or block hormones
• Development Toxicant = Can interfere
with normal development of a fetus or
child
• Reproductive Toxicant = Can harm
reproductive system

5. Findings :
Phthalates have been shown to be
reproductive and developmental toxins and
may contribute to what is known as
• Testicular dysgenesis syndrome
-increasing incidence of birth defects of the male
reproductive tract such as undescended testis, and lower
sperm count
 While a lot of attention has been focused on the
"demasculation" of boys by phthalates, women are not
immune to their effects. Phthalates are implicated in
premature puberty in girls.
 Phthalates are endocrine (hormone) disruptors, meaning
they interfere with normal brain function
 Phthalates send signals in the body that could result in
Autism, Breast Cancer, Testicular cancer and reduced sperm
counts

6. •It causes malformation of vital organs and
skeletal structure.
Rat testis
Left = Unexposed
Center and right = DEHP exposure during
development
Rat seminal vesicle
Left = Unexposed
Right = DEHP exposure during
development

7. Findings
Prenatal exposure to phtlalates
can cause brain damage:
 Attention deficit hyperactivity disorder (
Adhd)- characterized by either significant
difficulties of inattention or hyperactivity and
impulsiveness or a combination of the two
 Oppositional Defiant Disorder(ODO)- an
ongoing pattern of anger guided
disobedience, hostilely defiant behavior
toward authority figures which goes beyond
the bounds of normal childhood behavior

8. Exposure Route For Chemical
poisoning -- Dimethyl Phthalate
•Inhalation
•eye
•skin
•ingestion
Symptoms of Chemical poisoning –
Dimethyl Phthalate
•Eye irritation •Coma
•Upper respiratory system irritation •Gastrointestinal irritation
•Abdominal pain •Nausea
•Diarrhea •Vomiting
•Oral burns •Paralysis
•Coughing •Unconsciousness
•CNS depression
•Reduced blood pressure
Treatment List for Chemical
poisoning -- Dimethyl
Phthalate
•Decontamination, symptomatic and supportive
measures