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Sheffield
Healthcare
Gateway.

             Dr. James Lapworth
                  Business Manager
                        September 2012
Overview
• The University of Sheffield track record
• What is Sheffield Healthcare Gateway?
      • Team
      • Web portal
• How can we help?
• Case studies


21/02/2013 © The University of Sheffield
The University in Numbers

•   25,000 students
•   6,000 staff
•   £450m p.a. turnover
•   £100m p.a. research income
•   Top 10 UK research
    establishment
•   Top 100 Globally


•   Times Higher Ed. University of
    the Year (Nov 2011)
Rich Heritage:
           5 Nobel Prize winners



Lord Florey     Sir Harry Kroto     Dr Richard   Sir Hans Krebs Lord Porter
Medicine/       Chemistry           Roberts      Medicine/        Chemistry
Physiology                          Medicine/    Physiology
                  “Buckminster-     Physiology                       “Free
 “Penicillin”    fullerene (C60)”                  “Kreb’s Cycle”   Radicals”
                                     “Introns”
Knowledge Exchange – a serious business

£50m - Collaborative and Contract Research
£2.6m - Consultancy
£1.4m - Services and Testing
£2.2m - CPD
£4m - Regeneration and Development


Over £60m 2010-2011*
*HEBCI return 2010-2011
What is Sheffield Healthcare
Gateway?
• “A new centre dedicated to supporting health-related Knowledge
  Exchange activities across the University”
• Aiming to:
     • Increase knowledge transfer activity of health-related
       researchers
     • Build long-term partnerships with Industry
• Strong links with:
     • Sheffield Teaching Hospitals, Medilink networks, NHS research
       networks, KTNs
• Work closely with:
     • Commercial and Knowledge Exchange teams across the
       University (SEG, SSG, KTA, R&IS and Fusion IP)
  21/02/2013 © The University of Sheffield
How can we help business?
• Providing a responsive access point into the university
• Identifying expertise, skills and facilities which are
  relevant to a company’s needs
• Facilitating introductions and initial meetings
• Identifying sources of collaborative grant funding and
  coordinating applications
• Ongoing project management and relationship
  management support



21/02/2013 © The University of Sheffield
How can we help academics?
• Identifying potential new IP (with Fusion IP)
• Proof of concept funding: identifying funds, help with
  applications and project management support
• Identifying and liaising with potential collaborators
• Signposting and guidance through University processes
• Organising events to promote and support commercial
  activities
• Faculty Innovation Fund to support new interactions with
  Industry

21/02/2013 © The University of Sheffield
Building on Past Successes
“The Sheffield Health Innovation Centre (SHIC) at
University of Sheffield is providing a valuable solution to
this perennial problem by acting as a portal through
which collaboration with local businesses is channelled.
The work of the SHIC should be supported and
integrated into any future healthcare initiatives in the
city-region.’

                                           Breeze Report (2011) to Sheffield City Region LEP
                                            Re. challenges to accessing University expertise.



21/02/2013 © The University of Sheffield
Gateway Team




 Prof Richard Ross                         Dr Martin Whitaker      Dr Sue Smith
Faculty Lead for Innovation                  Business Manager      Business Manager




  Dr James Lapworth                         Ms Karen Booth      Mrs Lindsey Crowson
       Business Manager                      Business Manager    Gateway Administrator


21/02/2013 © The University of Sheffield
http://www.shef.ac.uk/shg
http://www.shef.ac.uk/shg
http://www.shef.ac.uk/shg
Faculty Innovation Fund:
• Available only to FMDH academics
• A “light touch”, rolling call for short-term
  pump-priming activities aiming to
  stimulate:
              •     1 consultancy project with industry, or;
              •     1 collaborative R&D contract with industry, or;
              •     1 industrial CASE Studentship with industry, or;
              •     1 patent application, leading to a license or
                    spinout opportunity

21/02/2013 © The University of Sheffield
Med-Tech Industry day, June 2012




 Speakers:
 • Prof Keith Burnett (University Vice Chancellor)
 • Dr Zahid Latif (Technology Strategy Board)
 • Dr Mehdi Tavakoli (Healthtech & Medicines KTN)
 • Dr Beken (Materials KTN)
 • Philippa Hedley (Sheffield City Region LEP)
 • + 5 technology presentations highlighting projects with industry partners
21/02/2013 © The University of Sheffield
Med-Tech Industry day, June 2012
137 Delegates - Industry (55); Academia (55); NHS (14);
Other (13) (map)

“A fantastic way to find out what's
going on nationally and locally in field
of Med Tech. Great way to network.”

“A superb event with an excellent range
of exhibitors and attendees.”


              *Feedback from Industry delegates



 21/02/2013 © The University of Sheffield
Publicity and Media




                      © The University of Sheffield 13 Jan 2011
Case Studies
“True” collaborative R&D:
     Co-development of rapid manufacturing processes
     for soft tissue prosthetics with Fripp Design Ltd.
     (AMP, Catcliffe)




        University                     White Rose         Wellcome
        Knowledge                    Health Innovation   Translational
     Transfer Funding                  Partnership          Award
          (£10k)                          (£40K)           (£510k)



21/02/2013 © The University of Sheffield
The University of Sheffield as a
                   “Virtual R&D Lab”:
           New product development with Ceramisys Ltd.                                (Sheffield)




                                                                 Technology
                      University
                                            EPSRC Industrial   Strategy Board   EPSRC Industrial
                      Knowledge
                                              Case award        Collaborative    Case award 2
                   Transfer Funding
                                                (£66K)              R&D             (£67K)
                        (£6k)
                                                                  (£880k)



© The University of Sheffield 13 Jan 2011
Innovative spin-outs:
  New “physiological hormone replacement” therapies
  addressing major clinical needs

• Diurnal ltd. – founded 2004
• Addressing clinical and patient
  needs in: adrenal insufficiency,
   rheumatoid arthritis, hypogonadism
   and hypothyroidism
• Recently completed successful
  phase 1 clinical trial (see link)


http://shg.sheffield.ac.uk/news/universityofsheffieldspinoutcompanydiurnala1.aspx
 21/02/2013 © The University of Sheffield
“Digital & Connected
                                       Healthcare”
        New assistive technologies to support self-management.




                heart failure, stroke, chronic pain…
                http://www.bbc.co.uk/news/health-11837457
© The University of Sheffield 13 Jan 2011
Technologies for Assisted
      Living:
       VIVOCA – “allows people              MAAVIS – “allows greatly
       with severe speech disability        simplified access to media,
       to communicate via a                 communications and the
       speech synthesiser.”                 web.”




© The University of Sheffield 13 Jan 2011
                                             http://maavis.fullmeasure.co.uk/
Oral Disease & Neuroscience:
      Oral mucosal model – “a               Mechanisms and models
      3D tissue model of the                of pain – ability to compare
      mucous membranes found                healthy vs diseased human
      in the mouth.”                        tissue




         Moharamzadeh K, et al (2009)           Rodd HD & Boissonade FM (2000)
         J Periodontol. 80(5):769-75.           Eur J Oral Sci. 108:467-474.


© The University of Sheffield 13 Jan 2011
Dr James Lapworth– Contacts

                    james.lapworth@sheffield.ac.uk


                    @JWLapworth


                    www.linkedin.com/in/jameslapworth


21/02/2013 © The University of Sheffield

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Sheffield Healthcare Gateway - Sept 2012

  • 1. Sheffield Healthcare Gateway. Dr. James Lapworth Business Manager September 2012
  • 2. Overview • The University of Sheffield track record • What is Sheffield Healthcare Gateway? • Team • Web portal • How can we help? • Case studies 21/02/2013 © The University of Sheffield
  • 3. The University in Numbers • 25,000 students • 6,000 staff • £450m p.a. turnover • £100m p.a. research income • Top 10 UK research establishment • Top 100 Globally • Times Higher Ed. University of the Year (Nov 2011)
  • 4. Rich Heritage: 5 Nobel Prize winners Lord Florey Sir Harry Kroto Dr Richard Sir Hans Krebs Lord Porter Medicine/ Chemistry Roberts Medicine/ Chemistry Physiology Medicine/ Physiology “Buckminster- Physiology “Free “Penicillin” fullerene (C60)” “Kreb’s Cycle” Radicals” “Introns”
  • 5. Knowledge Exchange – a serious business £50m - Collaborative and Contract Research £2.6m - Consultancy £1.4m - Services and Testing £2.2m - CPD £4m - Regeneration and Development Over £60m 2010-2011* *HEBCI return 2010-2011
  • 6. What is Sheffield Healthcare Gateway? • “A new centre dedicated to supporting health-related Knowledge Exchange activities across the University” • Aiming to: • Increase knowledge transfer activity of health-related researchers • Build long-term partnerships with Industry • Strong links with: • Sheffield Teaching Hospitals, Medilink networks, NHS research networks, KTNs • Work closely with: • Commercial and Knowledge Exchange teams across the University (SEG, SSG, KTA, R&IS and Fusion IP) 21/02/2013 © The University of Sheffield
  • 7. How can we help business? • Providing a responsive access point into the university • Identifying expertise, skills and facilities which are relevant to a company’s needs • Facilitating introductions and initial meetings • Identifying sources of collaborative grant funding and coordinating applications • Ongoing project management and relationship management support 21/02/2013 © The University of Sheffield
  • 8. How can we help academics? • Identifying potential new IP (with Fusion IP) • Proof of concept funding: identifying funds, help with applications and project management support • Identifying and liaising with potential collaborators • Signposting and guidance through University processes • Organising events to promote and support commercial activities • Faculty Innovation Fund to support new interactions with Industry 21/02/2013 © The University of Sheffield
  • 9. Building on Past Successes “The Sheffield Health Innovation Centre (SHIC) at University of Sheffield is providing a valuable solution to this perennial problem by acting as a portal through which collaboration with local businesses is channelled. The work of the SHIC should be supported and integrated into any future healthcare initiatives in the city-region.’ Breeze Report (2011) to Sheffield City Region LEP Re. challenges to accessing University expertise. 21/02/2013 © The University of Sheffield
  • 10. Gateway Team Prof Richard Ross Dr Martin Whitaker Dr Sue Smith Faculty Lead for Innovation Business Manager Business Manager Dr James Lapworth Ms Karen Booth Mrs Lindsey Crowson Business Manager Business Manager Gateway Administrator 21/02/2013 © The University of Sheffield
  • 14. Faculty Innovation Fund: • Available only to FMDH academics • A “light touch”, rolling call for short-term pump-priming activities aiming to stimulate: • 1 consultancy project with industry, or; • 1 collaborative R&D contract with industry, or; • 1 industrial CASE Studentship with industry, or; • 1 patent application, leading to a license or spinout opportunity 21/02/2013 © The University of Sheffield
  • 15. Med-Tech Industry day, June 2012 Speakers: • Prof Keith Burnett (University Vice Chancellor) • Dr Zahid Latif (Technology Strategy Board) • Dr Mehdi Tavakoli (Healthtech & Medicines KTN) • Dr Beken (Materials KTN) • Philippa Hedley (Sheffield City Region LEP) • + 5 technology presentations highlighting projects with industry partners 21/02/2013 © The University of Sheffield
  • 16. Med-Tech Industry day, June 2012 137 Delegates - Industry (55); Academia (55); NHS (14); Other (13) (map) “A fantastic way to find out what's going on nationally and locally in field of Med Tech. Great way to network.” “A superb event with an excellent range of exhibitors and attendees.” *Feedback from Industry delegates 21/02/2013 © The University of Sheffield
  • 17. Publicity and Media © The University of Sheffield 13 Jan 2011
  • 19. “True” collaborative R&D: Co-development of rapid manufacturing processes for soft tissue prosthetics with Fripp Design Ltd. (AMP, Catcliffe) University White Rose Wellcome Knowledge Health Innovation Translational Transfer Funding Partnership Award (£10k) (£40K) (£510k) 21/02/2013 © The University of Sheffield
  • 20. The University of Sheffield as a “Virtual R&D Lab”: New product development with Ceramisys Ltd. (Sheffield) Technology University EPSRC Industrial Strategy Board EPSRC Industrial Knowledge Case award Collaborative Case award 2 Transfer Funding (£66K) R&D (£67K) (£6k) (£880k) © The University of Sheffield 13 Jan 2011
  • 21. Innovative spin-outs: New “physiological hormone replacement” therapies addressing major clinical needs • Diurnal ltd. – founded 2004 • Addressing clinical and patient needs in: adrenal insufficiency, rheumatoid arthritis, hypogonadism and hypothyroidism • Recently completed successful phase 1 clinical trial (see link) http://shg.sheffield.ac.uk/news/universityofsheffieldspinoutcompanydiurnala1.aspx 21/02/2013 © The University of Sheffield
  • 22. “Digital & Connected Healthcare” New assistive technologies to support self-management. heart failure, stroke, chronic pain… http://www.bbc.co.uk/news/health-11837457 © The University of Sheffield 13 Jan 2011
  • 23. Technologies for Assisted Living: VIVOCA – “allows people MAAVIS – “allows greatly with severe speech disability simplified access to media, to communicate via a communications and the speech synthesiser.” web.” © The University of Sheffield 13 Jan 2011 http://maavis.fullmeasure.co.uk/
  • 24. Oral Disease & Neuroscience: Oral mucosal model – “a Mechanisms and models 3D tissue model of the of pain – ability to compare mucous membranes found healthy vs diseased human in the mouth.” tissue Moharamzadeh K, et al (2009) Rodd HD & Boissonade FM (2000) J Periodontol. 80(5):769-75. Eur J Oral Sci. 108:467-474. © The University of Sheffield 13 Jan 2011
  • 25. Dr James Lapworth– Contacts james.lapworth@sheffield.ac.uk @JWLapworth www.linkedin.com/in/jameslapworth 21/02/2013 © The University of Sheffield