Basic understanding of primordial germ cells

1. Primordial germ cells
PGC
NAME : JAYARAM C
CLASS : I-M.SC,
ROLL.NO: 12

2. CONTENTS
✓ Introduction
✓ History of PGC
✓ Morphology,histology of pgc
✓ Origin of primordial germ cells
✓ PGC in different chordates
✓ Transportation of primordial germ cells
✓ Application of primordial germ cells
✓ Ongoing research
✓ Referance
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3. INTRODUCTION
➢ Pgcs destined to develop into gametes.
➢ Gametes and pgc constitute the germplasm.
➢ Germplasm is paramount,somatoplasm ceases to exist
with the death of animals.
➢ Succeeding generation
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4. Morphology
Morphology
Histology
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All most similar
SHAPE: Oval shape,depentupon
species
SIZE :10 - 20 µm diameter,

5. ORIGIN OF PRIMORDIAL GERM CELLS
germplasm
sperm ovum
❑ Embryo gamets
❑ PGC inside embryo
❑
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PGC recognized early embryonic stage

6. 19/11/18PGC
6Primordial germ cells
Germinal epithelial origin Extragonadal origin
•Waldeyer (1870)
•PGC germinal epithilial of gonad
Germ cellls arise out side
Early period of embryonic
development and then
migrate
Gonads

7. 19/11/18PGC
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PGC IN DIFFERENT CHORDATES

8. PETROMYZON
)
In petromyzon,the PGC
arise from coelomic
epithelium
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9. FISHES
PGC
endoderm
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10. AMPHIBIANS
urodele amphibian
PGC
Postero-ventral part of the
lateral mesoderm
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11. Reptiles and birds
PGC Endoderm
of extra embryonic part
of the blastoderm
Anterior to the head
region of the embryo
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12. Mammals
PGC Endoderm
Mouse caudalregion
Human
endoderm of yolk sac
in the victinity of
allantoic stalk.
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13. TRANSPORTATION OF PGC
PGC orginate outside,they move to reach gonads.
they transported into two types
1-By blood stream in chick embryo.
2-By amoeboid movement in human embryo.
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14. ENTIRE PROCESS OF PGC
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PGC
GAMETES
EMBRYO
Inside embryo present in
(PGC)

15. ONGOING RESEARCH
ZIBRA FISH regenaration
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16. 19/11/18PGC
16Referance& source
TEXT BOOK;
✓ An Introduction to Embryology Paperback – 2012
by B.I. Balinsky (Author),
✓Textbook of Clinical Embryology Paperback – 1 Jul 2017
by Vishram Singh(Author)
Image source://www.bing.com/image
www.google.com/image
Artical referance: Primordial Germ Cells: Current Knowledge and
Perspectives
www.ncbi.nlm.nih.gov › … › Stem Cell Int › v.2016; 2016

17. “
”
Think globally, act locally
THANKYOU
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