1. MALARIA AND
BARTONELLOSIS.
MEDICAL
ENGLISH
Vera Bances Paul.
Paredes Campos ligia
Segura Ríos Patricia.
Rodas Regalado Carlota.
Pisfil Colchado Carlos.
Pintado Coronel Edwin.
2. BARTONELLO
SIS
What is it?
The human Bartonellosis "Peruvian wart" or "Carrion's disease" is
an infectious disease caused by a bacterium Bartonella
bacilliformis, which parasitizes red blood cells from human blood.
3. MALARIA
What is it?
infectious, serious and to
sometimes fatal, produced by
a
parasite transmitted by the
mosquito's Anopheles
5. MALARIA BARTONELLOSIS
Causative parasite: protozoa of Causative parasite: proteobacteria
the genus Plasmodium Bartonella bacilliformis
-four species: Plasmodium vivax, P.
Ovale, P. Malariae and P.
Falciparum (the most deadly)
Vector of this disease : female Main vector: female of the
mosquito of the genus Anopheles. mosquito Lutzomyia verrucarum
TRANSMISSION ROUTES TRANSMISSION ROUTES
-Direct drive through the bite of a ƒ - By the bite of the mosquito.
mosquito. ƒ - Transfusion with infected blood.
-Also be transmitted by blood
transfusions or by infected syringes.
6. COMMON SIGNS AND SYMPTOMS
MALARIA BARTONELLOSIS
FIRST STAGE Acute phase: (Carrion's
The classic symptoms disease
hemolytic anemia
fever jaundice
7. DIFFERENT SIGNS AND SYMPTOMS
MALARIA FIRST STAGE
shivering convulsions hemoglobinuria
arthralgia ( joint pain) vomiting retinal damage
8. DIFFERENT SIGNS AND SYMPTOMS
Acute phase: (Carrion's
BARTONELLOSIS FIRST disease
STAGE
pallor malaise
nonpainful hepatomegaly
lymphadeopathy
9. COMMON SIGNS AND SYMPTOMS
MALARIA BARTONELLOSIS
Chronic phase (or Peruvian wart
Severe malaria SECOND STAGE Peruvian Wart)
Hepatomegaly Splenomegaly
normal spleen enlarged spleen
10. DIFFERENT SIGNS AND SYMPTOMS
MALARIA SECOND STAGE
severe headache hypoglycemia
renal failure
cerebral ischemia
11. DIFFERENT SIGNS AND SYMPTOMS
BARTONELLOSIS Chronic phase (or Peruvian
wart Peruvian Wart)
"Peruvian warts" or "Peruvian
wart". myalgias
SECOND
STAGE
arthralgias
lymphadeopathy
12. What are the possible consequences?
Malaria Bartonellosis
The consequences are often If the infection is not
fatal, if not treated quickly. treated, the mortality rate can
be as high as 85%
13. What are the possible consequences?
Malaria Bartonellosis
Hemolytic anemia. Purple
thrombocytopenic
The rupture of a large number Complication hematologic
of red blood cells will produce recently reported that may occur
significant anemia. with evolution favorable.
14. What are the possible consequences?
Malaria Bartonellosis
Cerebral malaria, that usually Complications have been
ends in a box coma. reported neurological
15. What are the possible consequences?
Malaria Bartonellosis
Acute renal failure Acute hemolysis
Associated with fever
Accentuated due to hemolysis, manifested
as a decrease in the amount of urine.
Parasitized erythrocytes bartonellosis
16. Malaria treatment
Chloroquine 500 mg orally 1 time a
week
Adults: 500 mg every 8 hours for 3-10 days.
Quinine Children: 8.2 mg / kg every 8 hours for 3 to
10 days.
For travelers going to areas where it is
Alternative treatment known to occur Falciparum malaria, there
are several options for malaria: mefloquine,
atovaquone / proguanil and doxycycline.
tetracycline or clindamycin
17. Bartonellosis treatment
In general it is recommended to use:
•In addition to another antimicrobial
agent as a beta lactam.
•For the effective treatment of B.
CHLORAMPHENICOL
bacilliformis and protect against any
secondary bacterial infection
The rifampin or CIPROFLOXACIN,
STREPTOMYCIN,
streptomycin is used to
TETRACYCLINE OR
treat chronic bartonellosis ERYTHROMYCIN
19. Bartonellosis Diagnostics.
Reaction Polymerase Chain
Blood smears stained with
Giemsa.
Agar cultures and Cell
cultures.
Identification of the isolates.
Indirect fluorescent antibody
test
Western blot