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MALARIA AND
              BARTONELLOSIS.
       MEDICAL
       ENGLISH



Vera Bances Paul.
Paredes Campos ligia
Segura Ríos Patricia.
Rodas Regalado Carlota.
Pisfil Colchado Carlos.
Pintado Coronel Edwin.
BARTONELLO
    SIS
         What is it?

   The human Bartonellosis "Peruvian wart" or "Carrion's disease" is
          an infectious disease caused by a bacterium Bartonella
   bacilliformis, which parasitizes red blood cells from human blood.
MALARIA



          What is it?



          infectious, serious and to
          sometimes fatal, produced by
          a
          parasite transmitted by the
          mosquito's Anopheles
of
MALARIA                            BARTONELLOSIS


Causative parasite: protozoa of        Causative parasite: proteobacteria
the genus Plasmodium                    Bartonella bacilliformis

-four species: Plasmodium vivax, P.
Ovale, P. Malariae and P.
Falciparum (the most deadly)




Vector of this disease : female        Main vector: female of the
mosquito of the genus Anopheles.        mosquito Lutzomyia verrucarum


TRANSMISSION ROUTES                    TRANSMISSION ROUTES
-Direct drive through the bite of a     ƒ - By the bite of the mosquito.
mosquito.                               ƒ - Transfusion with infected blood.
-Also be transmitted by blood
transfusions or by infected syringes.
COMMON SIGNS AND SYMPTOMS

      MALARIA                                  BARTONELLOSIS


                           FIRST STAGE      Acute phase: (Carrion's
  The classic symptoms                             disease




                         hemolytic anemia




         fever                                      jaundice
DIFFERENT SIGNS AND SYMPTOMS
                   MALARIA                 FIRST STAGE


       shivering             convulsions                 hemoglobinuria




 arthralgia ( joint pain)      vomiting                  retinal damage
DIFFERENT SIGNS AND SYMPTOMS
                                     Acute phase: (Carrion's
   BARTONELLOSIS             FIRST          disease
                             STAGE
         pallor                            malaise




   nonpainful hepatomegaly
                                     lymphadeopathy
COMMON SIGNS AND SYMPTOMS

    MALARIA                                           BARTONELLOSIS

                                           Chronic phase (or Peruvian wart
   Severe malaria     SECOND STAGE                 Peruvian Wart)


       Hepatomegaly                                  Splenomegaly



                                     normal spleen        enlarged spleen
DIFFERENT SIGNS AND SYMPTOMS
         MALARIA         SECOND STAGE


    severe headache       hypoglycemia




      renal failure
                        cerebral ischemia
DIFFERENT SIGNS AND SYMPTOMS
     BARTONELLOSIS                         Chronic phase (or Peruvian
                                              wart Peruvian Wart)
  "Peruvian warts" or "Peruvian
             wart".                               myalgias




                                  SECOND
                                   STAGE

            arthralgias
                                                 lymphadeopathy
What are the possible consequences?

             Malaria                    Bartonellosis


The consequences are often       If the infection is not
fatal, if not treated quickly.   treated, the mortality rate can
                                 be as high as 85%
What are the possible consequences?

          Malaria                       Bartonellosis


   Hemolytic anemia.                       Purple
                                      thrombocytopenic

The rupture of a large number     Complication           hematologic
of red blood cells will produce   recently reported that may occur
significant anemia.               with evolution favorable.
What are the possible consequences?

          Malaria                   Bartonellosis



Cerebral malaria, that usually   Complications have been
ends in a box coma.              reported neurological
What are the possible consequences?

               Malaria                           Bartonellosis



         Acute renal failure                     Acute hemolysis


                                              Associated with fever
Accentuated due to hemolysis, manifested
as a decrease in the amount of urine.




                                           Parasitized erythrocytes bartonellosis
Malaria treatment
Chloroquine                    500 mg orally 1 time a
                               week




                     Adults: 500 mg every 8 hours for 3-10 days.
 Quinine             Children: 8.2 mg / kg every 8 hours for 3 to
                     10 days.




                                      For travelers going to areas where it is
Alternative treatment                 known to occur Falciparum malaria, there
                                      are several options for malaria: mefloquine,
                                      atovaquone / proguanil and doxycycline.
 tetracycline or clindamycin
Bartonellosis treatment
     In general it is recommended to use:

•In addition to another antimicrobial
agent as a beta lactam.
•For the effective treatment of B.
                                             CHLORAMPHENICOL
bacilliformis and protect against any
secondary bacterial infection




The rifampin or                         CIPROFLOXACIN,
                                        STREPTOMYCIN,
streptomycin is used to
                                        TETRACYCLINE OR
treat chronic bartonellosis             ERYTHROMYCIN
Malaria diagnosis.

Examination of samples of
 peripheral blood.
Detection of parasite
 antigens.
Molecular techniques.
Serology.
Bartonellosis Diagnostics.

Reaction Polymerase Chain
Blood smears stained with
 Giemsa.
Agar cultures and Cell
 cultures.
Identification of the isolates.
Indirect fluorescent antibody
 test
Western blot
10   comparative diagnosis

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  • 1. MALARIA AND BARTONELLOSIS. MEDICAL ENGLISH Vera Bances Paul. Paredes Campos ligia Segura Ríos Patricia. Rodas Regalado Carlota. Pisfil Colchado Carlos. Pintado Coronel Edwin.
  • 2. BARTONELLO SIS What is it? The human Bartonellosis "Peruvian wart" or "Carrion's disease" is an infectious disease caused by a bacterium Bartonella bacilliformis, which parasitizes red blood cells from human blood.
  • 3. MALARIA What is it? infectious, serious and to sometimes fatal, produced by a parasite transmitted by the mosquito's Anopheles
  • 4. of
  • 5. MALARIA BARTONELLOSIS Causative parasite: protozoa of Causative parasite: proteobacteria the genus Plasmodium Bartonella bacilliformis -four species: Plasmodium vivax, P. Ovale, P. Malariae and P. Falciparum (the most deadly) Vector of this disease : female Main vector: female of the mosquito of the genus Anopheles. mosquito Lutzomyia verrucarum TRANSMISSION ROUTES TRANSMISSION ROUTES -Direct drive through the bite of a ƒ - By the bite of the mosquito. mosquito. ƒ - Transfusion with infected blood. -Also be transmitted by blood transfusions or by infected syringes.
  • 6. COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS FIRST STAGE Acute phase: (Carrion's The classic symptoms disease hemolytic anemia fever jaundice
  • 7. DIFFERENT SIGNS AND SYMPTOMS MALARIA FIRST STAGE shivering convulsions hemoglobinuria arthralgia ( joint pain) vomiting retinal damage
  • 8. DIFFERENT SIGNS AND SYMPTOMS Acute phase: (Carrion's BARTONELLOSIS FIRST disease STAGE pallor malaise nonpainful hepatomegaly lymphadeopathy
  • 9. COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS Chronic phase (or Peruvian wart Severe malaria SECOND STAGE Peruvian Wart) Hepatomegaly Splenomegaly normal spleen enlarged spleen
  • 10. DIFFERENT SIGNS AND SYMPTOMS MALARIA SECOND STAGE severe headache hypoglycemia renal failure cerebral ischemia
  • 11. DIFFERENT SIGNS AND SYMPTOMS BARTONELLOSIS Chronic phase (or Peruvian wart Peruvian Wart) "Peruvian warts" or "Peruvian wart". myalgias SECOND STAGE arthralgias lymphadeopathy
  • 12. What are the possible consequences? Malaria Bartonellosis The consequences are often If the infection is not fatal, if not treated quickly. treated, the mortality rate can be as high as 85%
  • 13. What are the possible consequences? Malaria Bartonellosis Hemolytic anemia. Purple thrombocytopenic The rupture of a large number Complication hematologic of red blood cells will produce recently reported that may occur significant anemia. with evolution favorable.
  • 14. What are the possible consequences? Malaria Bartonellosis Cerebral malaria, that usually Complications have been ends in a box coma. reported neurological
  • 15. What are the possible consequences? Malaria Bartonellosis Acute renal failure Acute hemolysis Associated with fever Accentuated due to hemolysis, manifested as a decrease in the amount of urine. Parasitized erythrocytes bartonellosis
  • 16. Malaria treatment Chloroquine 500 mg orally 1 time a week Adults: 500 mg every 8 hours for 3-10 days. Quinine Children: 8.2 mg / kg every 8 hours for 3 to 10 days. For travelers going to areas where it is Alternative treatment known to occur Falciparum malaria, there are several options for malaria: mefloquine, atovaquone / proguanil and doxycycline. tetracycline or clindamycin
  • 17. Bartonellosis treatment In general it is recommended to use: •In addition to another antimicrobial agent as a beta lactam. •For the effective treatment of B. CHLORAMPHENICOL bacilliformis and protect against any secondary bacterial infection The rifampin or CIPROFLOXACIN, STREPTOMYCIN, streptomycin is used to TETRACYCLINE OR treat chronic bartonellosis ERYTHROMYCIN
  • 18. Malaria diagnosis. Examination of samples of peripheral blood. Detection of parasite antigens. Molecular techniques. Serology.
  • 19. Bartonellosis Diagnostics. Reaction Polymerase Chain Blood smears stained with Giemsa. Agar cultures and Cell cultures. Identification of the isolates. Indirect fluorescent antibody test Western blot