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It is a disorder characterized by
                   It is a disorder characterized by



             changes in mood ranging from mania to
              changes in mood ranging from mania to
                          depression
                          depression



a    feeling     of     comfort,             an overwhelming feeling of
stimulation and exaggerated                  sadness, anxiety, low self-
grandeur in which a person                   esteem, which can include
loses touch with reality                     suicidal thoughts and attempts
Mood within normal, which implies the
absence of depressed or elevated mood.




A patient with this disorder but is in
remission.
determining the level of
neurocognitive impairment

                in

 patients whose persists
   bipolar disorder in
        remission
Patients
        Patients                   The control group
                                   The control group
       (n = 63)
        (n = 63)                        (n = 63)
                                         (n = 63)



   54 bipolar I disorders     They have no current and past
9 type II bipolar disorders        psychiatric illness.


 5 with rapid cycling
Patients excluded:

      Patients taking corticosteroids or
antihypertensive drugs

Defining euthymic patients

       Score 7 or less on the scale:

        The Hamilton Depression Scale or Beck
        The Young Mania Scale or Altman
The radioimmunoassay test


                   confirmed that the patients
                  were eucortisolaemic
Patients with bipolar disorder
Patients with bipolar disorder
performed significantly lower
performed significantly lower
compared to healthy subjects.
compared to healthy subjects.
no significant   associated with     less
 differences       the further     affected
                  deterioration
large       intermediate   reduced effect
magnitude of   magnitude of
  effect           effect
large       reduced magnitude    middle and lower      significant
magnitude of        of effect       effect compared        degree of
  effect                            with memory and      heterogeneity
                                   executive functions
This study confirms earlier findings of:

Impaired executive
 functioning



                 Response inhibition
This study confirms earlier findings of:
     Is associated with poor
      psychosocial functioning
• For clinicians, these results reinforce
  the importance of assessing cognitive
  function in patients with bipolar
  disorder
The development of the treat is
important to reduce disability due to
chronic mental illnesses
Psiquiatria

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Psiquiatria

  • 1.
  • 2.
  • 3. It is a disorder characterized by It is a disorder characterized by changes in mood ranging from mania to changes in mood ranging from mania to depression depression a feeling of comfort, an overwhelming feeling of stimulation and exaggerated sadness, anxiety, low self- grandeur in which a person esteem, which can include loses touch with reality suicidal thoughts and attempts
  • 4. Mood within normal, which implies the absence of depressed or elevated mood. A patient with this disorder but is in remission.
  • 5. determining the level of neurocognitive impairment in patients whose persists bipolar disorder in remission
  • 6. Patients Patients The control group The control group (n = 63) (n = 63) (n = 63) (n = 63) 54 bipolar I disorders They have no current and past 9 type II bipolar disorders psychiatric illness. 5 with rapid cycling
  • 7. Patients excluded: Patients taking corticosteroids or antihypertensive drugs Defining euthymic patients Score 7 or less on the scale:  The Hamilton Depression Scale or Beck  The Young Mania Scale or Altman
  • 8. The radioimmunoassay test confirmed that the patients were eucortisolaemic
  • 9.
  • 10.
  • 11. Patients with bipolar disorder Patients with bipolar disorder performed significantly lower performed significantly lower compared to healthy subjects. compared to healthy subjects.
  • 12. no significant associated with less differences the further affected deterioration
  • 13. large intermediate reduced effect magnitude of magnitude of effect effect
  • 14. large reduced magnitude middle and lower significant magnitude of of effect effect compared degree of effect with memory and heterogeneity executive functions
  • 15. This study confirms earlier findings of: Impaired executive functioning Response inhibition
  • 16. This study confirms earlier findings of: Is associated with poor psychosocial functioning
  • 17. • For clinicians, these results reinforce the importance of assessing cognitive function in patients with bipolar disorder
  • 18. The development of the treat is important to reduce disability due to chronic mental illnesses