28. Paramecium Conjugation 1. Two paramecium individuals come in contact on their oral surface. 2. The micronuclei divide by meiosis to produce four haploid micronuclei. 3. Three micronuclei degenerate 4. The remaining micronucleus divides to form male and female pronuclei 5. Syngamy occurs 6. Male micronuclei are exchanged between conjugants. 7. Male and female pronuclei fuse and individuals separate 8. Old macronuclei are absorbed and replaced by new macronuclei