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Forensic Science

T. Trimpe 2006 http://sciencespot.net/
What makes up our blood?
• RED BLOOD CELLS (Erythrocytes) – The most abundant
  cells in our blood; they are produced in the bone marrow and
  contain a protein called hemoglobin that carries oxygen to our
  cells.
• WHITE BLOOD CELLS (Leukocytes) – They are part of
  the immune system and destroy infectious agents called
  pathogens.
• PLASMA – This is the yellowish liquid portion of blood that
  contains electrolytes, nutrients and vitamins, hormones,
  clotting factors, and proteins such as antibodies to fight
  infection.
• PLATELETS (Thrombocytes) – The clotting factors that are
  carried in the plasma; they clot together in a process called
  coagulation to seal a wound and prevent a loss of blood.
Blood Facts
The average adult has about FIVE liters of blood inside of
their body, which makes up 7-8% of their body weight.
Blood is living tissue that carries oxygen and nutrients to
all parts of the body, and carries carbon dioxide and other
waste products back to the lungs, kidneys and liver for
disposal. It also fights against infection and helps heal
wounds, so we can stay healthy.
There are about one billion red blood cells in two to three
drops of blood. For every 600 red blood cells, there are
about 40 platelets and one white cell.

                http://www.bloodbankofalaska.org/about_blood/index.html
Genetics of Blood Types
• Your blood type is established before you are BORN,
  by specific GENES inherited from your parents.

• You inherit one gene from your MOTHER and one
  from your FATHER.

• These genes determine your blood type by causing
  proteins called AGGLUTINOGENS to exist on the
  surface of all of your red blood cells.
What are blood types?
                                                                               Blood Types
There are 3 alleles or genes for blood                                     AA or AO = Type A
type: A, B, & O. Since we have 2 genes,                                    BB or BO = Type B
there are 6 possible combinations.                                           OO = Type O
                                                                             AB = Type AB




                 http://learn.genetics.utah.edu/units/basics/blood/types.cfm
How common is your blood type?


                           46.1%

                           38.8%

                           11.1%

                           3.9%
Blood Transfusions
A blood transfusion is a procedure in which blood is given to a patient through an
intravenous (IV) line in one of the blood vessels. Blood transfusions are done to replace
blood lost during surgery or a serious injury. A transfusion also may be done if a person’s
body can't make blood properly because of an illness.


Who can give you blood?                                             Universal Donor

People with TYPE O blood are called
Universal Donors, because they can give
blood to any blood type.

People with TYPE AB blood are called
Universal Recipients, because they can
receive any blood type.

Rh +  Can receive + or -
Rh -  Can only receive -
                                                                     Universal Recipient
Rh Factors
• Scientists sometimes study Rhesus monkeys
  to learn more about the human anatomy
  because there are certain similarities between
  the two species. While studying Rhesus
  monkeys, a certain blood protein was
  discovered. This protein is also present in the
  blood of some people. Other people, however,
  do not have the protein.
• The presence of the protein, or lack of it, is
  referred to as the Rh (for Rhesus) factor.              A+ A-
• If your blood does contain the protein, your
  blood is said to be Rh positive (Rh+). If your
                                                          B+ B-
  blood does not contain the protein, your blood         AB+ AB-
  is said to be Rh negative (Rh-).                        O+ O-
                http://www.fi.edu/biosci/blood/rh.html
Blood Evidence
• Blood samples – Can be analyzed to determine blood
  type and DNA, which can be matched to possible
  suspects.

• Blood droplets – Can be analyzed to give clues to the
  location of a crime, movement of a victim, and type of
  weapon.

• Blood spatter – Can be analyzed to determine
  patterns that give investigators clues to how a crime
  might have happened.
Microscopic
                Views
Bird Blood                   Fish Blood




               Horse Blood

Cat Blood                    Frog Blood




               Human Blood
Dog Blood                    Snake Blood

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Bloodbasics

  • 1. Forensic Science T. Trimpe 2006 http://sciencespot.net/
  • 2. What makes up our blood? • RED BLOOD CELLS (Erythrocytes) – The most abundant cells in our blood; they are produced in the bone marrow and contain a protein called hemoglobin that carries oxygen to our cells. • WHITE BLOOD CELLS (Leukocytes) – They are part of the immune system and destroy infectious agents called pathogens. • PLASMA – This is the yellowish liquid portion of blood that contains electrolytes, nutrients and vitamins, hormones, clotting factors, and proteins such as antibodies to fight infection. • PLATELETS (Thrombocytes) – The clotting factors that are carried in the plasma; they clot together in a process called coagulation to seal a wound and prevent a loss of blood.
  • 3. Blood Facts The average adult has about FIVE liters of blood inside of their body, which makes up 7-8% of their body weight. Blood is living tissue that carries oxygen and nutrients to all parts of the body, and carries carbon dioxide and other waste products back to the lungs, kidneys and liver for disposal. It also fights against infection and helps heal wounds, so we can stay healthy. There are about one billion red blood cells in two to three drops of blood. For every 600 red blood cells, there are about 40 platelets and one white cell. http://www.bloodbankofalaska.org/about_blood/index.html
  • 4. Genetics of Blood Types • Your blood type is established before you are BORN, by specific GENES inherited from your parents. • You inherit one gene from your MOTHER and one from your FATHER. • These genes determine your blood type by causing proteins called AGGLUTINOGENS to exist on the surface of all of your red blood cells.
  • 5. What are blood types? Blood Types There are 3 alleles or genes for blood AA or AO = Type A type: A, B, & O. Since we have 2 genes, BB or BO = Type B there are 6 possible combinations. OO = Type O AB = Type AB http://learn.genetics.utah.edu/units/basics/blood/types.cfm
  • 6. How common is your blood type? 46.1% 38.8% 11.1% 3.9%
  • 7. Blood Transfusions A blood transfusion is a procedure in which blood is given to a patient through an intravenous (IV) line in one of the blood vessels. Blood transfusions are done to replace blood lost during surgery or a serious injury. A transfusion also may be done if a person’s body can't make blood properly because of an illness. Who can give you blood? Universal Donor People with TYPE O blood are called Universal Donors, because they can give blood to any blood type. People with TYPE AB blood are called Universal Recipients, because they can receive any blood type. Rh +  Can receive + or - Rh -  Can only receive - Universal Recipient
  • 8. Rh Factors • Scientists sometimes study Rhesus monkeys to learn more about the human anatomy because there are certain similarities between the two species. While studying Rhesus monkeys, a certain blood protein was discovered. This protein is also present in the blood of some people. Other people, however, do not have the protein. • The presence of the protein, or lack of it, is referred to as the Rh (for Rhesus) factor. A+ A- • If your blood does contain the protein, your blood is said to be Rh positive (Rh+). If your B+ B- blood does not contain the protein, your blood AB+ AB- is said to be Rh negative (Rh-). O+ O- http://www.fi.edu/biosci/blood/rh.html
  • 9. Blood Evidence • Blood samples – Can be analyzed to determine blood type and DNA, which can be matched to possible suspects. • Blood droplets – Can be analyzed to give clues to the location of a crime, movement of a victim, and type of weapon. • Blood spatter – Can be analyzed to determine patterns that give investigators clues to how a crime might have happened.
  • 10. Microscopic Views Bird Blood Fish Blood Horse Blood Cat Blood Frog Blood Human Blood Dog Blood Snake Blood