1. © 2008 AUTONOM HEALTH ®
Apnoe Screening

2. © 2008 AUTONOM HEALTH ®
Atmung Herzvektor

3. © 2008 AUTONOM HEALTH ®
Das EDR Signal – ECG Derived Respiration
ZOOM
EDR
Herzfrequenz

4. © 2008 AUTONOM HEALTH ®
Apnoe Screening
Automated detection of obstructive sleep apnoea at different time scales using the
electrocardiogram
Philip de Chazal, Thomas Penzel and Conor Heneghan
Physiological Measurement 25 (2004) 967-983

5. © 2008 AUTONOM HEALTH ®
• 10 Hz Resampling
• FIR Filter fg = 1 Hz
High-Resolution EDR
EDR Basics

6. © 2008 AUTONOM HEALTH ®
Quantifizierung der Atmungstätigkeit
Hilbert Transformation
H(EDR) = abs(EDR * 1/(π*t))
Vogelperspektive

7. © 2008 AUTONOM HEALTH ®
Respiration Activity Overview

8. © 2008 AUTONOM HEALTH ®
Apnoe Screening

9. © 2008 AUTONOM HEALTH ®
Obstruktive Schlaf Apnoe
OSA has been associated with several
cardiovascular diseases, most notably
hypertension, ischemic heart disease,
heart failure, stroke, cardiac arrhythmias,
and pulmonary hypertension.
Sleep-Disordered Breathing and Cardiovascular Disease
Robert Wolk, MD, PhD; Tomas Kara, MD; Virend K. Somers, MD, PhD
(Circulation. 2003;108:9-12)

10. © 2008 AUTONOM HEALTH ®
“Traditional” Holter
Arrhythmias
Holter
Recording
treat
Arrhythmias

11. © 2008 AUTONOM HEALTH ®
Arrhythmias
Holter
Recording
treat
Arrhythmias
?
treat
Cause of
Arrhythmia
”Beyond” Holter

12. © 2008 AUTONOM HEALTH ®
OSA as Cause of Arrhythmias
Arrhythmias
OSA
treat
OSA/SAS
Medilog AR
Advanced Holter
Recording

13. © 2008 AUTONOM HEALTH ®
OSA  Arrhythmien
• Sinus arrest
• SA Block
• AV Block
Pausen,
Bardykardie

14. © 2008 AUTONOM HEALTH ®
Arrhythmia Apnea

15. © 2008 AUTONOM HEALTH ®
Regulation ?