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Cognitive
Performance: What
moves the needle?
Leon Wurfel

OptimOZ – www.optimoz.com.au
Introduction
•   Cognitive performance and why it is important to me
•   Tools to measure and optimise cognitive performance
•   The experiment:
    •   The “lab”
    •   Variables
    •   Method

•   Outcomes:
    •   Limitations
    •   What else did we learn?
    •   What actually “moved the needle”?

•   Questions/Discussion
Cognitive performance
•   Cognitive performance = making the most of your brain power = self
    improvement
•   How do you do everything at once?
    •   Succeed at your job
    •   Run a business
    •   Learn and develop
    •   Be a good partner

Got to make the most of things
•   Have gone from meditation – productivity techniques – QS/biohacking
    techniques
Cognitive performance
•   How do you measure it?
    •   Psychometric tests: IQ, Executive functioning etc
    •   Proxies for the above (i.e. online versions)
    •   QS techniques: dual n-back, free cell, Lumosity

•   How do you improve it?
    •   Supplements
    •   Nootropics
    •   Healthy lifestyle
    •   Training
The experiment – the lab
•   Online cognitive testing lab: Quantified mind (www.quantified-
    mind.com)
•   Can set up your own experiments and collaborate
•   Has an analytics engine to do all the stats work for you
The experiment – the method and
variables
•   Testing a range of cognitive   •   Tested for impacts of:
    functions:                         •   Modafinil
    •   Choice Reaction Time           •   Piracetam
    •   Color-Word (Inhibition)        •   BP Coffee
    •   Visual Matching                •   BP compliant diet
    •   Sorting                        •   General supplements
    •   Finger Tapping                 •   Upgraded aging
    •   Attentional Focus              •   Mindfulness (that day)
    •   Coding                         •   Mindfulness (day before)
    •   Self-Paced 3-Back              •   Creatine
                                       •   Binaural beats
                                       •   Super supplementing B vits
The experiment – the method
•   Aiming for 50 sessions (@~15 min each)


•   Started about 3 months ago


•   So far have completed 15 sessions (life gets in the way)


•   Going to keep the study going and see where it goes
Limitation #1 – Practice effects
•   A practice effect is where you get better due to better skill at the tests.
    This confounds the outcome of the experiment


•   Quantified-Mind stats engine takes care of all that for you


•   Or you can do your own regressions/residuals blah blah blah - YUK
(note that exporting data from quantified mind isn’t very user friendly)
Limitation #1 – Practice effects
Limitation #1 – Practice effects
Session                    1   2   3   4   5   6   7   8   9   10   11   12   13   14
Attentional Focus         507 509 507 536 502 502 572 490 497 577 565 527 547 546
Choice Reaction Time      569 553 569 571 602 635 617 527 507 587 625 603 567 585
Coding                    560 590 560 641 607 604 676 648 643 657 650 639 650 663
Color-Word (Inhibition)   609 591 609 606 612 624 603 623 613 602 632 631 619 633
Finger Tapping            599 362 599 559 543 612 584 580 607 586 623 607 603 640
Self-Paced 3-Back         550 494 550 570 568 561 556 579 592 590 602 603 593 623
Sorting                   605 562 605 615 611 613 620 617 623 632 641 620 621 609
Visual Matching           598 543 598 578 594 590 583 601 609 605 606 610 605 605
Limitation #2 – Sample size
•   Only 15 data points – is this enough to draw any conclusions from?
•   Exacerbated testing across so many variables
         Variable                   %
         Modafinil                      43%
         Piracetam                      86%
         BP Coffee                      79%
         BP compliant diet              43%
         General supplements            79%
         Upgraded aging                 57%
         Mindfulness (that day)         21%
         Mindfulness (day before)        7%
         Creatine                        0%
         Binaural beats                 36%
         B vits                         64%
Variable                   %
What else did we learn? Modafinil                                     43%
• Tracking your behaviour can tell     Piracetam                      86%
  you some surprising things           BP Coffee                      79%
                                       BP compliant diet              43%
   • Which behaviours are habits?
                                       General supplements            79%
   • What are confounding factors that Upgraded aging                 57%
     affect your behaviour
                                       Mindfulness (that day)         21%
                                       Mindfulness (day before)        7%
                                       Creatine                        0%
                                       Binaural beats                 36%
                                       B vits                         64%
What moved the needle?
•   Attentional focus?
What moved the needle?
•   Attentional focus?
What moved the needle?
•   Choice reaction time?
What moved the needle?
•   Choice reaction time?
What moved the needle?
•   Coding?
What moved the needle?
•   Coding?




•   Also a weak association with piracetam
What moved the needle?
•   Colour word inhibition?
What moved the needle?
•   Colour word inhibition?




•   Also a weak association with piracetam
What moved the needle?
•   Attentional focus?
What moved the needle?
•   Finger tapping?
What moved the needle?
•   Finger tapping?




•   Modafinil and BP compliant diet were weak associations
What moved the needle?
•   Self paced 3-back?
What moved the needle?
•   Self paced 3-back?




•   Piracetam has a weak association with increased performance
What moved the needle?
•   Sorting?




•   Modafinil and bi-naural beats had weak impacts on performance
Variable                   %
Conclusion                               Modafinil                      43%
•   B-vitamin “super                     Piracetam                      86%
    supplementation” and modafinil       BP Coffee                      79%
    had the most significant
    improvements                         BP compliant diet              43%
•   Piracetam, BP compliant diet, bi-    General supplements            79%
    naural beats have weak impacts
    that could warrant further           Upgraded aging                 57%
    investigation                        Mindfulness (that day)         21%
•   Experiment will continue in order    Mindfulness (day before)        7%
    to deliver more conclusive results
                                         Creatine                        0%
                                         Binaural beats                 36%
                                         B vits                         64%
Discussion/Questions

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Qs cognitive performance preso 130403

  • 1. Cognitive Performance: What moves the needle? Leon Wurfel OptimOZ – www.optimoz.com.au
  • 2. Introduction • Cognitive performance and why it is important to me • Tools to measure and optimise cognitive performance • The experiment: • The “lab” • Variables • Method • Outcomes: • Limitations • What else did we learn? • What actually “moved the needle”? • Questions/Discussion
  • 3. Cognitive performance • Cognitive performance = making the most of your brain power = self improvement • How do you do everything at once? • Succeed at your job • Run a business • Learn and develop • Be a good partner Got to make the most of things • Have gone from meditation – productivity techniques – QS/biohacking techniques
  • 4. Cognitive performance • How do you measure it? • Psychometric tests: IQ, Executive functioning etc • Proxies for the above (i.e. online versions) • QS techniques: dual n-back, free cell, Lumosity • How do you improve it? • Supplements • Nootropics • Healthy lifestyle • Training
  • 5. The experiment – the lab • Online cognitive testing lab: Quantified mind (www.quantified- mind.com) • Can set up your own experiments and collaborate • Has an analytics engine to do all the stats work for you
  • 6. The experiment – the method and variables • Testing a range of cognitive • Tested for impacts of: functions: • Modafinil • Choice Reaction Time • Piracetam • Color-Word (Inhibition) • BP Coffee • Visual Matching • BP compliant diet • Sorting • General supplements • Finger Tapping • Upgraded aging • Attentional Focus • Mindfulness (that day) • Coding • Mindfulness (day before) • Self-Paced 3-Back • Creatine • Binaural beats • Super supplementing B vits
  • 7. The experiment – the method • Aiming for 50 sessions (@~15 min each) • Started about 3 months ago • So far have completed 15 sessions (life gets in the way) • Going to keep the study going and see where it goes
  • 8. Limitation #1 – Practice effects • A practice effect is where you get better due to better skill at the tests. This confounds the outcome of the experiment • Quantified-Mind stats engine takes care of all that for you • Or you can do your own regressions/residuals blah blah blah - YUK (note that exporting data from quantified mind isn’t very user friendly)
  • 9. Limitation #1 – Practice effects
  • 10. Limitation #1 – Practice effects Session 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Attentional Focus 507 509 507 536 502 502 572 490 497 577 565 527 547 546 Choice Reaction Time 569 553 569 571 602 635 617 527 507 587 625 603 567 585 Coding 560 590 560 641 607 604 676 648 643 657 650 639 650 663 Color-Word (Inhibition) 609 591 609 606 612 624 603 623 613 602 632 631 619 633 Finger Tapping 599 362 599 559 543 612 584 580 607 586 623 607 603 640 Self-Paced 3-Back 550 494 550 570 568 561 556 579 592 590 602 603 593 623 Sorting 605 562 605 615 611 613 620 617 623 632 641 620 621 609 Visual Matching 598 543 598 578 594 590 583 601 609 605 606 610 605 605
  • 11. Limitation #2 – Sample size • Only 15 data points – is this enough to draw any conclusions from? • Exacerbated testing across so many variables Variable % Modafinil 43% Piracetam 86% BP Coffee 79% BP compliant diet 43% General supplements 79% Upgraded aging 57% Mindfulness (that day) 21% Mindfulness (day before) 7% Creatine 0% Binaural beats 36% B vits 64%
  • 12. Variable % What else did we learn? Modafinil 43% • Tracking your behaviour can tell Piracetam 86% you some surprising things BP Coffee 79% BP compliant diet 43% • Which behaviours are habits? General supplements 79% • What are confounding factors that Upgraded aging 57% affect your behaviour Mindfulness (that day) 21% Mindfulness (day before) 7% Creatine 0% Binaural beats 36% B vits 64%
  • 13. What moved the needle? • Attentional focus?
  • 14. What moved the needle? • Attentional focus?
  • 15. What moved the needle? • Choice reaction time?
  • 16. What moved the needle? • Choice reaction time?
  • 17. What moved the needle? • Coding?
  • 18. What moved the needle? • Coding? • Also a weak association with piracetam
  • 19. What moved the needle? • Colour word inhibition?
  • 20. What moved the needle? • Colour word inhibition? • Also a weak association with piracetam
  • 21. What moved the needle? • Attentional focus?
  • 22. What moved the needle? • Finger tapping?
  • 23. What moved the needle? • Finger tapping? • Modafinil and BP compliant diet were weak associations
  • 24. What moved the needle? • Self paced 3-back?
  • 25. What moved the needle? • Self paced 3-back? • Piracetam has a weak association with increased performance
  • 26. What moved the needle? • Sorting? • Modafinil and bi-naural beats had weak impacts on performance
  • 27. Variable % Conclusion Modafinil 43% • B-vitamin “super Piracetam 86% supplementation” and modafinil BP Coffee 79% had the most significant improvements BP compliant diet 43% • Piracetam, BP compliant diet, bi- General supplements 79% naural beats have weak impacts that could warrant further Upgraded aging 57% investigation Mindfulness (that day) 21% • Experiment will continue in order Mindfulness (day before) 7% to deliver more conclusive results Creatine 0% Binaural beats 36% B vits 64%