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LUMINEX
    CORPORATION
    First Quarter 2011
    Results of Operations
    May 9, 2011


    Patrick J. Balthrop, President and Chief Executive Officer
    Harriss T. Currie, Vice President and Chief Financial Officer




1                                                                   Leading. Innovating. Growing.
Safe Harbor
    Certain statements made during the course of this presentation may not be purely historical and consequently may
    be forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including
    but not limited to: statements made regarding our partners’ commitment to, expansion of, and end-customer
    demand for our technology; long-term demand for and quarterly variability in bulk orders of consumables; volatility
    in consumables revenue and distribution and growth of such revenue during 2011 and beyond; the market launch
    of xTAG GPP, its technical capabilities, and the anticipated market size, demand and regulatory approvals therefor;
    our system and assay product pipeline and anticipated timelines for regulatory approvals and market release,
    including for our RVP FAST and NeoPlex 4 assays; our collaboration with Partners HealthCare and its ability to
    accelerate the development and commercialization of novel assays to address unmet clinical needs; the full
    commercial launch of our MAGPIX instrument, including expected market demand and future distribution therefor;
    future R&D and SG&A expenditures, variability thereof, and long-term targets therefor; our commitment to deliver
    revenue growth and manage operating costs; the strength of our balance sheet and sustainable levels of days
    sales outstanding; the markets we and our partners are targeting and their expected growth; our partnership model
    and the ability of our partners and our installed base to drive future growth in demand for our technology; the
    ability of our technology to enhance productivity and efficiency; our strategic outlook and growth plan for our
    business for 2011 and beyond; our long term financial targets; operational trends, including those related to sales
    of consumables, royalty revenues and inventory levels; our business outlook and projections about revenues, cash
    flow, system shipments, expenses and market conditions, and their anticipated impact on Luminex; information
    regarding development, timing and performance of new products; and, any statements of the plans, strategies and
    objectives of management for future operations. These forward looking statements speak only as of the date hereof
    and are based on our current beliefs and expectations and are subject to known or unknown risks and
    uncertainties some of which are beyond the company’s control that could cause actual results or plans to differ
    materially and adversely from those anticipated in the forward looking statements. Factors that could cause or
    contribute to such differences are detailed in our press release or in our annual, quarterly, or other filings with the
    Securities and Exchange Commission. We undertake no obligation to update these forward looking statements.
    Also, certain non-GAAP financial measures as defined by SEC Regulation G, may be covered in this presentation.
    To the extent that any non-GAAP financial measures are covered, a presentation of and reconciliation to the most
    directly comparable GAAP financial measures will be included in this presentation and/or be available on our
    website at www.luminexcorp.com in accordance with Regulation G.




2                                                                                              Leading. Innovating. Growing.
Agenda

         1Q11 Highlights

         1Q11 Financial Review

         2011 Guidance Update

         Q&A



3                                Leading. Innovating. Growing.
1Q11 Highlights
    Employees and office in Tokyo are safe; experienced minimal disruption


    •   Consolidated 1Q revenue of         •   In May, received CE Mark for
        $43.3M (+30% Y/Y):                     our xTAG® GPP assay
        •   Consumables of $15.0M (+53%)
                                           •   Collaboration with Partners
        •   Assay sales of $9.6M (+25%)        HealthCare in Boston
    •   Consolidated gross margin of       •   In April, received the Medical
        71%, +250bps Y/Y                       Design Excellence Award for
    •   Operating income of 19% of             MAGPIX ®
        consolidated revenue               •   Third consecutive year on
    •   Net income of $4.5M, or $0.11          Forbes’ list of the 25 fastest-
        per fully diluted share                growing technology companies



4                                                             Leading. Innovating. Growing.
Record 1Q Consumables

         5-YR CAGR = +28%



                                                 88%




5                           Leading. Innovating. Growing.
xTAG® GPP Gains CE Mark
                                        •   xTAG Gastrointestinal
                                            Pathogen Panel (GPP) CE
                                            Mark received in May
    NeoPlex4™ CE Mark RVP-FAST US IVD
                                        •   Value Proposition of GPP:
                                             •   Targets 15 pathogens
                                                 (viruses, parasites, toxins
                                                 and bacteria)
                                             •   Strong clinical results
                                                 (sensitivity/specificity)
    Meningitis CE Mark
                                        •   Substantial market
                                            opportunity ~ $150M WW

                                        •   Synergies with RVP and
    Flock Monitor - USDA   Fungal ASR       current EU installed base


6                                                        Leading. Innovating. Growing.
Collaboration with Partners HealthCare
    •   Partners HealthCare is a premier
        integrated health system and one of
        the nation's leading biomedical
        research organizations                  "Luminex's xMAP technology provides an ideal
                                                platform for Partners HealthCare to translate novel
                                                biomarker discoveries into cutting-edge tests and
    •   Collaboration enables Partners          accelerate adoption of new molecular tests to provide
        HealthCare Center for Personalized      the best clinical care for patients."
        Genetic Medicine (PCPGM) to develop
        novel molecular diagnostic assays                                Dr. Heidi Rehm, Director
                                                     PCPGM's Laboratory for Molecular Medicine at
        based on biomarkers discovered within                                 Partners HealthCare
        Partners HealthCare entities

    •   These innovative molecular diagnostic
        tests will operate on Luminex's
        proprietary xMAP® platform




7                                                                        Leading. Innovating. Growing.
MAGPIX® Limited Launch Update
    •   Solid early uptake –
        113 units to date

    •   Compact system offers




                                     Price and throughput
        single or multiplex (up to                             LX 200™
        50 analytes per well)
                                                                   Immunoassay Research Market Facts
        capabilities
                                                                                       North America market: ~ $400M
                                                                                        Customer mix: Academia (40%)
    •   Protein and nucleic acid
                                                                                    

                                                                                       ~135,000 US researchers
        applications                                                                   39% of ELISA users interested in
                                                                                        multiplexing in next 12 months*
                                                               MAGPIX®
    •   Cost advantages over
        ELISA
                                                            * Source: Biocompare Immunoassays 2008 – An End User Survey

    •   Initial target market:
        Immunoassay research                                    Potential Installations

8                                                                                               Leading. Innovating. Growing.
Agenda

         1Q11 Highlights

         1Q11 Financial Review

         2011 Guidance Update

         Q&A



9                                Leading. Innovating. Growing.
1Q11 Income Statement
     ($ in thousands - except per share amounts)   1Q 2011      1Q 2010           Variance
     Revenue                                       $ 43,275     $ 33,252          $ 10,023
     Gross Margin %                                      71%          68%                   3%
     Operating Expenses                                22,434       19,028             (3,406)
     Operating Profit                                   8,294        3,748              4,546
     Operating Profit %                                  19%          11%                   8%

     Net Income:                                   $    4,461   $    1,875        $     2,586
     EPS, basic                                    $     0.11   $     0.05        $       0.06
     EPS, diluted                                  $     0.11   $     0.05        $       0.06



10                                                                     Leading. Innovating. Growing.
1Q11 Segment Results
     ($ in thousands - except per share amounts)
                                                   1Q 2011       1Q 2010          Variance
 Revenue
  Technology & Strategic Partnerships              $   31,935    $   25,216      $     6,719
  Assays & Related Products                            11,340         8,036            3,304
  Total Revenue                                        43,275        33,252           10,023

 Operating Income (Loss)
  Technology & Strategic Partnerships                   8,656         4,296             4,360
  Assays & Related Products                              (362)         (548)              186
  Total Operating Income                           $    8,294    $    3,748      $      4,546

     Total Operating Margin                              19%           11%                  8%




11                                                                    Leading. Innovating. Growing.
1Q11 Revenue Distribution
                       (1)            (2)
 Segment       Sales         Growth         % of Sales                   Highlights
 Systems        $7.7           15%              18%      197 multiplexing analyzers, includes 38 MAGPIX

 Consumables   $15.0           53%              35%      19 bulk orders total $13.3M range: $105K - $9M

 Royalties      $7.3           24%              17%      Overall adoption of xMAP; 1Q minimum payments

 Assays         $9.6           25%              22%      CF and RVP Franchises ~ 88% of assay revenue

 Other          $3.8           16%              8%       Service and maintenance on growing installed base

                                                                                             Footnotes:
                                                                                             (1) Dollars in millions
                                                                                             (2)Year-over-year




12                                                                                Leading. Innovating. Growing.
Potential for Operating Leverage
     Research and Development ($M)              Sales, General and Administrative
     ($ in millions)                            (% of Total Revenue)

                       17.5%   16.5%   of Rev




      •     Focus on driving growth             •    Continued focus on
            through significant                      operating leverage,
            continued investment in R&D              particularly in G&A



13                                                                     Leading. Innovating. Growing.
Strong Balance Sheet
     ($ in millions)
                           3/31/11    12/31/10          12/31/09

     Cash & Investments    $ 129.2    $ 123.9            $ 119.6

     Accounts Receivable   $   14.4   $   20.9           $    22.1

     DSO                        30         47                   53

     Inventory             $   25.5   $   24.9           $    17.5

     Inventory Turns            0.5        0.5                 0.8

     Total Assets          $ 265.4    $ 265.8            $ 248.0

     Current Ratio             11.5        8.7                 7.2

     Days Payable               35         56                   62




14                                               Leading. Innovating. Growing.
Cash & Investment Flow
 ($ in millions)




                                 + 11.2

                                                      - 1.2
                                                                         - 2.0                   + 0.5           129.2

                                                                                        - 3.3
              123.9




      Footnotes:
      (1) OCF excludes the excess income tax benefit from employee stock-based awards

15                                                                                              Leading. Innovating. Growing.
2011 Guidance Reiterated
     •   2011 revenue guidance of $163-$170M
     •   Reiteration of 2011 guidance based on our expectation:
         •   1H11 consumable sales (in $) likely to be greater than 2H11
         •   Limited contribution from new assays (e.g. qBead, GPP, CYP2D6)
         •   Normal-to-light Influenza-Like-Illness (ILI) season




16                                                          Leading. Innovating. Growing.
Long Term Financial Targets
     •   Long-term Compounded Annual Revenue Growth of 20+ Percent
     •   All Metrics Except Revenue Growth Expressed in Percent of Annual Revenue



                                                                                                 Long Term
         Metric                                    2007    2008    2009    2010   1Q11             Targets
         Revenue                                  100%    100%    100%    100%    100%

         Revenue Growth (YoY)                      42%     39%     16%     17%    30%                   20+%

         Gross Profit                              61%     68%     67%     68%    71%             65% - 75%

         R&D Expense                               21%     18%     17%     17%    18%                    15%

         Pretax Income (Loss)                     (3)%      4%     6%*      8%    19%             25% - 35%

     *Adjusted for the settlement of litigation




17                                                                                       Leading. Innovating. Growing.
2011 Starting Out Strong…

                                               Near-Term Catalysts
                                               Additional MAGPIX distribution,
                                             Investor event (July 25) at AACC

                                        Strong Financial Position
                                             Record 1Q revenue; +30% Y/Y
                                       Cash on the balance sheet of $129.2M


                                         Robust Product Pipeline
          GPP CE Mark (Rec’d), RVP Fast in 2011, NeoPlex4 CE Mark at YE11


                      Leveraging Partners to Drive Adoption
       Strong 1Q consumable revenue growth (+53%) driven by our top partners




18                                                        Leading. Innovating. Growing.
Agenda

          Corporate Overview

          Recent Highlights

          Financial Review

          Q&A



19                             Leading. Innovating. Growing.

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Luminex Q1 2011 Earnings Call

  • 1. LUMINEX CORPORATION First Quarter 2011 Results of Operations May 9, 2011 Patrick J. Balthrop, President and Chief Executive Officer Harriss T. Currie, Vice President and Chief Financial Officer 1 Leading. Innovating. Growing.
  • 2. Safe Harbor Certain statements made during the course of this presentation may not be purely historical and consequently may be forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including but not limited to: statements made regarding our partners’ commitment to, expansion of, and end-customer demand for our technology; long-term demand for and quarterly variability in bulk orders of consumables; volatility in consumables revenue and distribution and growth of such revenue during 2011 and beyond; the market launch of xTAG GPP, its technical capabilities, and the anticipated market size, demand and regulatory approvals therefor; our system and assay product pipeline and anticipated timelines for regulatory approvals and market release, including for our RVP FAST and NeoPlex 4 assays; our collaboration with Partners HealthCare and its ability to accelerate the development and commercialization of novel assays to address unmet clinical needs; the full commercial launch of our MAGPIX instrument, including expected market demand and future distribution therefor; future R&D and SG&A expenditures, variability thereof, and long-term targets therefor; our commitment to deliver revenue growth and manage operating costs; the strength of our balance sheet and sustainable levels of days sales outstanding; the markets we and our partners are targeting and their expected growth; our partnership model and the ability of our partners and our installed base to drive future growth in demand for our technology; the ability of our technology to enhance productivity and efficiency; our strategic outlook and growth plan for our business for 2011 and beyond; our long term financial targets; operational trends, including those related to sales of consumables, royalty revenues and inventory levels; our business outlook and projections about revenues, cash flow, system shipments, expenses and market conditions, and their anticipated impact on Luminex; information regarding development, timing and performance of new products; and, any statements of the plans, strategies and objectives of management for future operations. These forward looking statements speak only as of the date hereof and are based on our current beliefs and expectations and are subject to known or unknown risks and uncertainties some of which are beyond the company’s control that could cause actual results or plans to differ materially and adversely from those anticipated in the forward looking statements. Factors that could cause or contribute to such differences are detailed in our press release or in our annual, quarterly, or other filings with the Securities and Exchange Commission. We undertake no obligation to update these forward looking statements. Also, certain non-GAAP financial measures as defined by SEC Regulation G, may be covered in this presentation. To the extent that any non-GAAP financial measures are covered, a presentation of and reconciliation to the most directly comparable GAAP financial measures will be included in this presentation and/or be available on our website at www.luminexcorp.com in accordance with Regulation G. 2 Leading. Innovating. Growing.
  • 3. Agenda 1Q11 Highlights 1Q11 Financial Review 2011 Guidance Update Q&A 3 Leading. Innovating. Growing.
  • 4. 1Q11 Highlights Employees and office in Tokyo are safe; experienced minimal disruption • Consolidated 1Q revenue of • In May, received CE Mark for $43.3M (+30% Y/Y): our xTAG® GPP assay • Consumables of $15.0M (+53%) • Collaboration with Partners • Assay sales of $9.6M (+25%) HealthCare in Boston • Consolidated gross margin of • In April, received the Medical 71%, +250bps Y/Y Design Excellence Award for • Operating income of 19% of MAGPIX ® consolidated revenue • Third consecutive year on • Net income of $4.5M, or $0.11 Forbes’ list of the 25 fastest- per fully diluted share growing technology companies 4 Leading. Innovating. Growing.
  • 5. Record 1Q Consumables 5-YR CAGR = +28% 88% 5 Leading. Innovating. Growing.
  • 6. xTAG® GPP Gains CE Mark • xTAG Gastrointestinal Pathogen Panel (GPP) CE Mark received in May NeoPlex4™ CE Mark RVP-FAST US IVD • Value Proposition of GPP: • Targets 15 pathogens (viruses, parasites, toxins and bacteria) • Strong clinical results (sensitivity/specificity) Meningitis CE Mark • Substantial market opportunity ~ $150M WW • Synergies with RVP and Flock Monitor - USDA Fungal ASR current EU installed base 6 Leading. Innovating. Growing.
  • 7. Collaboration with Partners HealthCare • Partners HealthCare is a premier integrated health system and one of the nation's leading biomedical research organizations "Luminex's xMAP technology provides an ideal platform for Partners HealthCare to translate novel biomarker discoveries into cutting-edge tests and • Collaboration enables Partners accelerate adoption of new molecular tests to provide HealthCare Center for Personalized the best clinical care for patients." Genetic Medicine (PCPGM) to develop novel molecular diagnostic assays Dr. Heidi Rehm, Director PCPGM's Laboratory for Molecular Medicine at based on biomarkers discovered within Partners HealthCare Partners HealthCare entities • These innovative molecular diagnostic tests will operate on Luminex's proprietary xMAP® platform 7 Leading. Innovating. Growing.
  • 8. MAGPIX® Limited Launch Update • Solid early uptake – 113 units to date • Compact system offers Price and throughput single or multiplex (up to LX 200™ 50 analytes per well) Immunoassay Research Market Facts capabilities  North America market: ~ $400M Customer mix: Academia (40%) • Protein and nucleic acid   ~135,000 US researchers applications  39% of ELISA users interested in multiplexing in next 12 months* MAGPIX® • Cost advantages over ELISA * Source: Biocompare Immunoassays 2008 – An End User Survey • Initial target market: Immunoassay research Potential Installations 8 Leading. Innovating. Growing.
  • 9. Agenda 1Q11 Highlights 1Q11 Financial Review 2011 Guidance Update Q&A 9 Leading. Innovating. Growing.
  • 10. 1Q11 Income Statement ($ in thousands - except per share amounts) 1Q 2011 1Q 2010 Variance Revenue $ 43,275 $ 33,252 $ 10,023 Gross Margin % 71% 68% 3% Operating Expenses 22,434 19,028 (3,406) Operating Profit 8,294 3,748 4,546 Operating Profit % 19% 11% 8% Net Income: $ 4,461 $ 1,875 $ 2,586 EPS, basic $ 0.11 $ 0.05 $ 0.06 EPS, diluted $ 0.11 $ 0.05 $ 0.06 10 Leading. Innovating. Growing.
  • 11. 1Q11 Segment Results ($ in thousands - except per share amounts) 1Q 2011 1Q 2010 Variance Revenue Technology & Strategic Partnerships $ 31,935 $ 25,216 $ 6,719 Assays & Related Products 11,340 8,036 3,304 Total Revenue 43,275 33,252 10,023 Operating Income (Loss) Technology & Strategic Partnerships 8,656 4,296 4,360 Assays & Related Products (362) (548) 186 Total Operating Income $ 8,294 $ 3,748 $ 4,546 Total Operating Margin 19% 11% 8% 11 Leading. Innovating. Growing.
  • 12. 1Q11 Revenue Distribution (1) (2) Segment Sales Growth % of Sales Highlights Systems $7.7 15% 18% 197 multiplexing analyzers, includes 38 MAGPIX Consumables $15.0 53% 35% 19 bulk orders total $13.3M range: $105K - $9M Royalties $7.3 24% 17% Overall adoption of xMAP; 1Q minimum payments Assays $9.6 25% 22% CF and RVP Franchises ~ 88% of assay revenue Other $3.8 16% 8% Service and maintenance on growing installed base Footnotes: (1) Dollars in millions (2)Year-over-year 12 Leading. Innovating. Growing.
  • 13. Potential for Operating Leverage Research and Development ($M) Sales, General and Administrative ($ in millions) (% of Total Revenue) 17.5% 16.5% of Rev • Focus on driving growth • Continued focus on through significant operating leverage, continued investment in R&D particularly in G&A 13 Leading. Innovating. Growing.
  • 14. Strong Balance Sheet ($ in millions) 3/31/11 12/31/10 12/31/09 Cash & Investments $ 129.2 $ 123.9 $ 119.6 Accounts Receivable $ 14.4 $ 20.9 $ 22.1 DSO 30 47 53 Inventory $ 25.5 $ 24.9 $ 17.5 Inventory Turns 0.5 0.5 0.8 Total Assets $ 265.4 $ 265.8 $ 248.0 Current Ratio 11.5 8.7 7.2 Days Payable 35 56 62 14 Leading. Innovating. Growing.
  • 15. Cash & Investment Flow ($ in millions) + 11.2 - 1.2 - 2.0 + 0.5 129.2 - 3.3 123.9 Footnotes: (1) OCF excludes the excess income tax benefit from employee stock-based awards 15 Leading. Innovating. Growing.
  • 16. 2011 Guidance Reiterated • 2011 revenue guidance of $163-$170M • Reiteration of 2011 guidance based on our expectation: • 1H11 consumable sales (in $) likely to be greater than 2H11 • Limited contribution from new assays (e.g. qBead, GPP, CYP2D6) • Normal-to-light Influenza-Like-Illness (ILI) season 16 Leading. Innovating. Growing.
  • 17. Long Term Financial Targets • Long-term Compounded Annual Revenue Growth of 20+ Percent • All Metrics Except Revenue Growth Expressed in Percent of Annual Revenue Long Term Metric 2007 2008 2009 2010 1Q11 Targets Revenue 100% 100% 100% 100% 100% Revenue Growth (YoY) 42% 39% 16% 17% 30% 20+% Gross Profit 61% 68% 67% 68% 71% 65% - 75% R&D Expense 21% 18% 17% 17% 18% 15% Pretax Income (Loss) (3)% 4% 6%* 8% 19% 25% - 35% *Adjusted for the settlement of litigation 17 Leading. Innovating. Growing.
  • 18. 2011 Starting Out Strong… Near-Term Catalysts Additional MAGPIX distribution, Investor event (July 25) at AACC Strong Financial Position Record 1Q revenue; +30% Y/Y Cash on the balance sheet of $129.2M Robust Product Pipeline GPP CE Mark (Rec’d), RVP Fast in 2011, NeoPlex4 CE Mark at YE11 Leveraging Partners to Drive Adoption Strong 1Q consumable revenue growth (+53%) driven by our top partners 18 Leading. Innovating. Growing.
  • 19. Agenda Corporate Overview Recent Highlights Financial Review Q&A 19 Leading. Innovating. Growing.