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SYSTEMIC LUPUS The “classic” autoimmune disease
Statistics ,[object Object],[object Object],[object Object]
Many Organ Systems Involved ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Kidney ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Kidney ,[object Object],[object Object]
Kidney Involvement When: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Both Kidneys Always Involved ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Best Way To Access: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Markers of inflammation or immune function: ,[object Object],[object Object],[object Object],[object Object]
Kidney biopsy is the best way to diagnosis and determine treatment of Lupus Nephritis. It tells the degree of inflammation  and scarring present .
WHO Classifications - biopsy VI  Scarred V  Memberanous IV  Diffuse Proliferative III  Focal Proliferative II  Mesangial I  Normal
If no scarring, then treat all: ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Treatments ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treat Before Scarring ,[object Object],[object Object],[object Object]
How to Determine Which Medication to Administer ,[object Object],[object Object],[object Object],[object Object]
Lupus has become a very treatable disease. Only good studies can make it more treatable.
 
THANK YOU Remember, being involved in good studies will help lupus therapy for  you  and everyone.

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Your Kidneys Matter: Lupus and the Damage It Can Do

  • 1. SYSTEMIC LUPUS The “classic” autoimmune disease
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Kidney biopsy is the best way to diagnosis and determine treatment of Lupus Nephritis. It tells the degree of inflammation and scarring present .
  • 12. WHO Classifications - biopsy VI Scarred V Memberanous IV Diffuse Proliferative III Focal Proliferative II Mesangial I Normal
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20. Lupus has become a very treatable disease. Only good studies can make it more treatable.
  • 21.  
  • 22. THANK YOU Remember, being involved in good studies will help lupus therapy for you and everyone.